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The map label for this gene is cbf2 [H]

Identifier: 21244891

GI number: 21244891

Start: 4907609

End: 4908571

Strand: Reverse

Name: cbf2 [H]

Synonym: XAC4174

Alternate gene names: 21244891

Gene position: 4908571-4907609 (Counterclockwise)

Preceding gene: 21244892

Following gene: 21244890

Centisome position: 94.84

GC content: 66.46

Gene sequence:

>963_bases
ATGCATCTGGTTGGCCCACGGGCCGAACCCGACGGCGGCGCTGACCGCCGTCGGTTCTTGTCTAACGGAGGTTGTCTCAT
GGTTTCCCCACGTGTGTTGCCTGCCGCGCTAGCGGCGAGCCTGATCTTCTGCGTGGCAGCGGCGCAGGCCGCCACTGCCG
CATCCGATGTCCGCAGCAACCAGGCAACGGTGCTGCAGATCGGCAAACAATCGCTCGATGCGCAGGAGTACCGCGCGCTT
GCGCTGGCCGGCTTGCCACAGGATTTCAATCCGGCCAGTGCGGCCGACCCGGAATGTGTGCGCGAATTCGCCGATCGCCT
GTTGCTGGTGGAGCAGGCCCGGCGTGCGCATTTGCAGGACGACCCGGTCGTGGCCGCGCGTATACGTCAGGCGACCGATG
CGATCCTGGCCAAGGCCGTGCAGACGCGTGCGCGCGAAAGCGCGCAGATCGATGCTGCGCAGATCAAGGCGCAATTCGAT
GCGCATCCACACGATTACGATGAAGTGCACTTGAGCCATGTGTTCGTGGCGTTGAAGCCGCAGGGCGAGGCGCGGCGTGG
GACGCCCCTGACCGATGCTCAGGCGCTTGCCCGGGCGCAGCGCCTCAAGCAACAGCTGGAGTCCGGCACACCGTTTGCCG
AACTGGCGATGCGGCAGTCCGACGATGCCAGTACTGCGGCCGAGGGCGGCGAACTGTCGCCGATGTTTCTGCGCAATGTG
GCGGACGCGTTTGTCGCGCCGGTGCAGGACCTGGCGGTGGGGCAGGTGTCGGTGCCGGTACGTGGCCCGGAGGGTTACCA
CCTGATCCGTGTCGATGCGCGGCGACCGGCAACCCTGGACAGCGCACGCGGACAGATCGAGGTGCAATTGCGCGACCAGG
CGGCTGCCAACGCATTGGAGCAATTGCGTCAGGCCAATCCGGTGCGCTTCGATCGCGCCGCGCTGGAAGCGGCGCTGCGT
TGA

Upstream 100 bases:

>100_bases
GGATTTCATTACGCGCGACGAGGACTTTCGCCTGATCACCACCGATGACCCGAAGGGCGCCATCGCTTATCTGCGTGCGC
GCGGCAAGCACGAATAATGG

Downstream 100 bases:

>100_bases
GGCGCCGGGCGCGATGACACGCCGACTGCAAACGACGCATGGGGCAGGCGATCGATCGACCTGGCCATGGCCGGGCACGG
TTGCTGCGATCGTGCTGATG

Product: peptidyl-prolyl cis-trans isomerase

Products: Isomerized Proline [C]

Alternate protein names: Major antigen peb4A [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MHLVGPRAEPDGGADRRRFLSNGGCLMVSPRVLPAALAASLIFCVAAAQAATAASDVRSNQATVLQIGKQSLDAQEYRAL
ALAGLPQDFNPASAADPECVREFADRLLLVEQARRAHLQDDPVVAARIRQATDAILAKAVQTRARESAQIDAAQIKAQFD
AHPHDYDEVHLSHVFVALKPQGEARRGTPLTDAQALARAQRLKQQLESGTPFAELAMRQSDDASTAAEGGELSPMFLRNV
ADAFVAPVQDLAVGQVSVPVRGPEGYHLIRVDARRPATLDSARGQIEVQLRDQAAANALEQLRQANPVRFDRAALEAALR

Sequences:

>Translated_320_residues
MHLVGPRAEPDGGADRRRFLSNGGCLMVSPRVLPAALAASLIFCVAAAQAATAASDVRSNQATVLQIGKQSLDAQEYRAL
ALAGLPQDFNPASAADPECVREFADRLLLVEQARRAHLQDDPVVAARIRQATDAILAKAVQTRARESAQIDAAQIKAQFD
AHPHDYDEVHLSHVFVALKPQGEARRGTPLTDAQALARAQRLKQQLESGTPFAELAMRQSDDASTAAEGGELSPMFLRNV
ADAFVAPVQDLAVGQVSVPVRGPEGYHLIRVDARRPATLDSARGQIEVQLRDQAAANALEQLRQANPVRFDRAALEAALR
>Mature_320_residues
MHLVGPRAEPDGGADRRRFLSNGGCLMVSPRVLPAALAASLIFCVAAAQAATAASDVRSNQATVLQIGKQSLDAQEYRAL
ALAGLPQDFNPASAADPECVREFADRLLLVEQARRAHLQDDPVVAARIRQATDAILAKAVQTRARESAQIDAAQIKAQFD
AHPHDYDEVHLSHVFVALKPQGEARRGTPLTDAQALARAQRLKQQLESGTPFAELAMRQSDDASTAAEGGELSPMFLRNV
ADAFVAPVQDLAVGQVSVPVRGPEGYHLIRVDARRPATLDSARGQIEVQLRDQAAANALEQLRQANPVRFDRAALEAALR

Specific function: Assist In The Folding Of Extracytoplasmic Proteins. Essential For The Survival Of E.Coli In Stationary Phase. [C]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

None

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: 5.2.1.8 [C]

Molecular weight: Translated: 34359; Mature: 34359

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLVGPRAEPDGGADRRRFLSNGGCLMVSPRVLPAALAASLIFCVAAAQAATAASDVRSN
CCCCCCCCCCCCCHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QATVLQIGKQSLDAQEYRALALAGLPQDFNPASAADPECVREFADRLLLVEQARRAHLQD
CHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
DPVVAARIRQATDAILAKAVQTRARESAQIDAAQIKAQFDAHPHDYDEVHLSHVFVALKP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHEEEEEEEEEECC
QGEARRGTPLTDAQALARAQRLKQQLESGTPFAELAMRQSDDASTAAEGGELSPMFLRNV
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHCCCCCCCHHHHHHH
ADAFVAPVQDLAVGQVSVPVRGPEGYHLIRVDARRPATLDSARGQIEVQLRDQAAANALE
HHHHHHHHHHHCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCCEEEEEEHHHHHHHHHH
QLRQANPVRFDRAALEAALR
HHHHCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MHLVGPRAEPDGGADRRRFLSNGGCLMVSPRVLPAALAASLIFCVAAAQAATAASDVRSN
CCCCCCCCCCCCCHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QATVLQIGKQSLDAQEYRALALAGLPQDFNPASAADPECVREFADRLLLVEQARRAHLQD
CHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
DPVVAARIRQATDAILAKAVQTRARESAQIDAAQIKAQFDAHPHDYDEVHLSHVFVALKP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHEEEEEEEEEECC
QGEARRGTPLTDAQALARAQRLKQQLESGTPFAELAMRQSDDASTAAEGGELSPMFLRNV
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHCCCCCCCHHHHHHH
ADAFVAPVQDLAVGQVSVPVRGPEGYHLIRVDARRPATLDSARGQIEVQLRDQAAANALE
HHHHHHHHHHHCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCCEEEEEEHHHHHHHHHH
QLRQANPVRFDRAALEAALR
HHHHCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proline Imidic Peptide Bonds In Oligopeptides [C]

Specific reaction: Cis-Trans Isomerization Of Proline Imidic Peptide Bonds In Oligopeptides. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10688204 [H]