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The map label for this gene is czcC [H]

Identifier: 21244879

GI number: 21244879

Start: 4894548

End: 4895819

Strand: Reverse

Name: czcC [H]

Synonym: XAC4162

Alternate gene names: 21244879

Gene position: 4895819-4894548 (Counterclockwise)

Preceding gene: 21244880

Following gene: 21244878

Centisome position: 94.6

GC content: 71.62

Gene sequence:

>1272_bases
ATGTGGTTGCGACTGACGGCGCTTGCCGTCTTCGCGGTGGTGCCGTGCGCCAAGGCGCAGGACCTGCCGCCCAAACCCGC
GCTGACGCTGGACGACGCCATTGCGCGCGTCGCCCGCCAGCACCCCGATCTGCGCCTGGCCGATGGCCAACGCGCAGCCC
TCACCGCCGAAGCCGAGCGCGACGCGCTGCGTCCGCCGTTGCGCGTCGGCGCCGAACTGGAAAACGTCTTCGGCACCGGT
CCCACCCGCGCGCTGGACCAGGCCGAACTCACCGTCACCCTGGCCGGCGTGCTGGAACGCGGCGGCAAGCTCGACGCGCG
CCGCACCCTGGCGCAAGCGCGTCTCGATGCGCTGGCACCGCAACGCGCCCTGGCCCGGCTCGACGTCTTGGCCGAGGTGG
CGCGGCGTTACCTGGCCATCGGCATGGCCGCGCAGCGGCACGCGGCGGCGCTGGAACTGCTGATCCAGCGCCAGCGCACC
GTCAGCGCTGCGCGCCAACGGCTGCAGGCCGGCGCATCGCCCGAATCGGTGCTGCTGACCGCCCAGGCGCTGCAGGCGCG
CGCAGAACTCGAACGCGACCGCGCCCAGCAGGAACTGCACGCGGCACGCCGCCAGTTGGCCGTGCTGTGGGGCGAGCGCA
CGCCGCAGTTCGGCGCGATCACCGGCGACCCGCTGCAGCTGCCGGCGATTCCCGAGTTCGAGGTGCTGGCACAACTGCTC
GATGCCACGCCGGAACTGGCGCGCTTGAACGGCGAGCAGCGCGTGCGCGAAGCCCGTGTGCGGCTGGCGCGCAGCCAGGC
GCGCCCGGATCTGGACTGGCAGGTGGGCGTGCGCCGGCTCGAAGGCAATGACGCCACTGCGTTGCTCGGCAGCGTCTGGC
TGCCATTGGGTAGCGCTGCACGCGCGCAACCGGAGATTCGCGCTGCCGAAGCCGAGCTGGCGTTGCTGGATATCGAACGC
CAATCGCAGGCGTTGGTGCTCTACGCAACCCTGGCCGATGCGCATGGCCGCTACCGCGCTGCGCAGCTGGAAGTGACGCG
CATGCGCGAGGATGTACTGCCCGCGCTCGCACGCGCCGATGCCGCCGCCGAGCGCGCCTATCGTGCTGGCGCCACCAGTT
ATCTGGACTGGGCGCAGCTGCAGGCGCAACGCAGCGAGGCACGTCGGCAGCAACTGGCTGCTGCGTCGGAAGCGCAGACC
GCGTTGATCGAAATCCAGCGCCTGACCGGGCAGCCGTTCGTACGCGATCCTGCTGCGCAGGTGACGCCATGA

Upstream 100 bases:

>100_bases
TCGCATCTGAGCGAGACCGGATTGCGTCCTCCGATCGCGGCCTGATGCATCGCCGGCAGCTGCCGGCCTGTCCATCGATC
CCGATTCCGGAGACACCCTC

Downstream 100 bases:

>100_bases
ACGCGGTTTCCGTATTGCGTTGTCGTGCCGTGTGCACGTGCCCGCTTGAATCTGCCGCATCCGCATCCGCATCCGCATCC
GCATCCGCGCCCAGTGCTCG

Product: cation efflux system protein

Products: NA

Alternate protein names: Cation efflux system protein CzcC [H]

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MWLRLTALAVFAVVPCAKAQDLPPKPALTLDDAIARVARQHPDLRLADGQRAALTAEAERDALRPPLRVGAELENVFGTG
PTRALDQAELTVTLAGVLERGGKLDARRTLAQARLDALAPQRALARLDVLAEVARRYLAIGMAAQRHAAALELLIQRQRT
VSAARQRLQAGASPESVLLTAQALQARAELERDRAQQELHAARRQLAVLWGERTPQFGAITGDPLQLPAIPEFEVLAQLL
DATPELARLNGEQRVREARVRLARSQARPDLDWQVGVRRLEGNDATALLGSVWLPLGSAARAQPEIRAAEAELALLDIER
QSQALVLYATLADAHGRYRAAQLEVTRMREDVLPALARADAAAERAYRAGATSYLDWAQLQAQRSEARRQQLAAASEAQT
ALIEIQRLTGQPFVRDPAAQVTP

Sequences:

>Translated_423_residues
MWLRLTALAVFAVVPCAKAQDLPPKPALTLDDAIARVARQHPDLRLADGQRAALTAEAERDALRPPLRVGAELENVFGTG
PTRALDQAELTVTLAGVLERGGKLDARRTLAQARLDALAPQRALARLDVLAEVARRYLAIGMAAQRHAAALELLIQRQRT
VSAARQRLQAGASPESVLLTAQALQARAELERDRAQQELHAARRQLAVLWGERTPQFGAITGDPLQLPAIPEFEVLAQLL
DATPELARLNGEQRVREARVRLARSQARPDLDWQVGVRRLEGNDATALLGSVWLPLGSAARAQPEIRAAEAELALLDIER
QSQALVLYATLADAHGRYRAAQLEVTRMREDVLPALARADAAAERAYRAGATSYLDWAQLQAQRSEARRQQLAAASEAQT
ALIEIQRLTGQPFVRDPAAQVTP
>Mature_423_residues
MWLRLTALAVFAVVPCAKAQDLPPKPALTLDDAIARVARQHPDLRLADGQRAALTAEAERDALRPPLRVGAELENVFGTG
PTRALDQAELTVTLAGVLERGGKLDARRTLAQARLDALAPQRALARLDVLAEVARRYLAIGMAAQRHAAALELLIQRQRT
VSAARQRLQAGASPESVLLTAQALQARAELERDRAQQELHAARRQLAVLWGERTPQFGAITGDPLQLPAIPEFEVLAQLL
DATPELARLNGEQRVREARVRLARSQARPDLDWQVGVRRLEGNDATALLGSVWLPLGSAARAQPEIRAAEAELALLDIER
QSQALVLYATLADAHGRYRAAQLEVTRMREDVLPALARADAAAERAYRAGATSYLDWAQLQAQRSEARRQQLAAASEAQT
ALIEIQRLTGQPFVRDPAAQVTP

Specific function: CzcC protein appears to modify the specificity of the system, perhaps by acting on the CzcB protein. When the CzcC protein is added to CzcA and CzcB, the efflux system gains specificity for cadmium and cobalt [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 46108; Mature: 46108

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWLRLTALAVFAVVPCAKAQDLPPKPALTLDDAIARVARQHPDLRLADGQRAALTAEAER
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEECCCCCCEEECHHHH
DALRPPLRVGAELENVFGTGPTRALDQAELTVTLAGVLERGGKLDARRTLAQARLDALAP
HHCCCCHHHCCHHHHHCCCCCCCHHCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCH
QRALARLDVLAEVARRYLAIGMAAQRHAAALELLIQRQRTVSAARQRLQAGASPESVLLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
AQALQARAELERDRAQQELHAARRQLAVLWGERTPQFGAITGDPLQLPAIPEFEVLAQLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
DATPELARLNGEQRVREARVRLARSQARPDLDWQVGVRRLEGNDATALLGSVWLPLGSAA
HCCHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHCCCCCC
RAQPEIRAAEAELALLDIERQSQALVLYATLADAHGRYRAAQLEVTRMREDVLPALARAD
CCCCCHHHHHHHEEEEEECCCCCEEEEEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
AAAERAYRAGATSYLDWAQLQAQRSEARRQQLAAASEAQTALIEIQRLTGQPFVRDPAAQ
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
VTP
CCC
>Mature Secondary Structure
MWLRLTALAVFAVVPCAKAQDLPPKPALTLDDAIARVARQHPDLRLADGQRAALTAEAER
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEECCCCCCEEECHHHH
DALRPPLRVGAELENVFGTGPTRALDQAELTVTLAGVLERGGKLDARRTLAQARLDALAP
HHCCCCHHHCCHHHHHCCCCCCCHHCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCH
QRALARLDVLAEVARRYLAIGMAAQRHAAALELLIQRQRTVSAARQRLQAGASPESVLLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
AQALQARAELERDRAQQELHAARRQLAVLWGERTPQFGAITGDPLQLPAIPEFEVLAQLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
DATPELARLNGEQRVREARVRLARSQARPDLDWQVGVRRLEGNDATALLGSVWLPLGSAA
HCCHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHCCCCCC
RAQPEIRAAEAELALLDIERQSQALVLYATLADAHGRYRAAQLEVTRMREDVLPALARAD
CCCCCHHHHHHHEEEEEECCCCCEEEEEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
AAAERAYRAGATSYLDWAQLQAQRSEARRQQLAAASEAQTALIEIQRLTGQPFVRDPAAQ
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
VTP
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2678100; 7766206 [H]