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The map label for this gene is fldY [H]

Identifier: 21244871

GI number: 21244871

Start: 4883920

End: 4885227

Strand: Reverse

Name: fldY [H]

Synonym: XAC4154

Alternate gene names: 21244871

Gene position: 4885227-4883920 (Counterclockwise)

Preceding gene: 21244875

Following gene: 21244870

Centisome position: 94.39

GC content: 71.48

Gene sequence:

>1308_bases
ATGCAGCCGAGCCCGGAACCGAATCTGCGTCACCTTTACGCGCTGGTCGTGGTGCACCAGGCCGGAAGCGTCAGCGCGGC
GGCGCCGCGGGTGAATTTGTCGCAGCCGGCCCTGACCCAGGCCGTGGCGCGATTGGAGCAGCAACTGGGCGTGCGCCTGT
TCGACCGGCACCCAGGCGGCATGTCGGCCACCGAGGCTGCCGGGTTGCTGGTGCCGCGTATCGAGCGGGTGCTGGCGCAT
CTGGGCCGGGGGATCGGGGTCGCGCGTCGCGCGCTGCGCCTGCCGGCGCGCGCTGGCCTGGAGCGGCGGGTGTCGCTGGG
CCAGCTGCAGGCCCTGGTGGCGGTGGATGTGGCAGGCAGTTACGCGTTGGCGGCGGTGCGCGCCGGCGTTTCGCAGCCGG
CGATCTATCGCGCGGTGCAAGCGCTGGCCGATGTGATCGAAGTGCCGCTGACGGTACGCCGCGGCAAGACCATGCAGCCC
ACGCCGGTGGCGCTGCGGCTGTTGCGGCAGGTGCGGCTGGCGCTGGCCGAGTTGCGCGCCGGTCTGGACGAGGTGGCCGC
ATTGCGTTCGCAGCACGCCGGCCGCCTCACCCTGGGGGTGATGCCGCTGGCGCGCGCGATTCTGTTGCCGCAGGTGCTGG
CGCGGTTTGCGCATGCGCACCCGGGCGCCAGCGTCCAGGTGGTGGAGGGCCCGTACGAGCAATTGCTGGCGCATCTGCGC
GAGGGTGGCCTGGATCTGTTGATCGGTGCGCTGCGCGACCCGTTGCCGGTACGCGATGTGCTGCAGGAGCCGCTGTTCGA
CGACGAACCGGTGATCGTGGCGCGTAGCGGCCACCCCTTGGCCGGGCAGGGCTACGCGTTTGCGCAACTGCGCGATTATC
CCTGGGTGATCGCCGCCGCCGGCACGCCGGTGCGCGCGCGCTGGGAGCAGCTGTTCGGCGACCACCAGCTGGAGCCGCCG
CCGGTGCGCATCGAATGCGGCGCCGAACTGACCGTGCGTGGCCTGCTGCTGGAGGGCGACTGGTTGACCTTGATGTCGCG
CGACCAGTTCCTGTTCGAGCGCCGCGCCGGCCTGCTGGAGGAGATCGGCAGCGCCGGGCCGCTGCTGCGCCGGCAGATCG
GCATGACCACGCGCAGCGACTGGTATCCCACCCGGATGCAGTCGGCCTTCGTGCAGACGTTGCGGCAGGTCTGCGCCGAA
CGCGTGCAGCCTGCCGATGCCCAGGGCGGGCCGTTTCGCTATTGCCCCGCTGCCTGTGCGCAGCCGCCGTTGCGTTTACG
CGCGGCCAAGTCAGAATCGGGTTCCTGA

Upstream 100 bases:

>100_bases
CATCCATCCTCGTTAAGAATGCGCCGAGTCTGGCCGGGCAGAGCCAGCTGGCTCAAGATTCATTTGAGGTATGCATATTG
GTTTTGCTTATAGTTAGAGC

Downstream 100 bases:

>100_bases
TGAAGACGGACCACTGATGTTGCCCGATTGGGTCACAGGCACTTGGCTGCTGGCACTGGACTGGGCGATCCGCCTGGCCG
CACTGCTCTGGATTCCCGCC

Product: transcriptional regulator

Products: NA

Alternate protein names: Pca operon transcriptional activator [H]

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MQPSPEPNLRHLYALVVVHQAGSVSAAAPRVNLSQPALTQAVARLEQQLGVRLFDRHPGGMSATEAAGLLVPRIERVLAH
LGRGIGVARRALRLPARAGLERRVSLGQLQALVAVDVAGSYALAAVRAGVSQPAIYRAVQALADVIEVPLTVRRGKTMQP
TPVALRLLRQVRLALAELRAGLDEVAALRSQHAGRLTLGVMPLARAILLPQVLARFAHAHPGASVQVVEGPYEQLLAHLR
EGGLDLLIGALRDPLPVRDVLQEPLFDDEPVIVARSGHPLAGQGYAFAQLRDYPWVIAAAGTPVRARWEQLFGDHQLEPP
PVRIECGAELTVRGLLLEGDWLTLMSRDQFLFERRAGLLEEIGSAGPLLRRQIGMTTRSDWYPTRMQSAFVQTLRQVCAE
RVQPADAQGGPFRYCPAACAQPPLRLRAAKSESGS

Sequences:

>Translated_435_residues
MQPSPEPNLRHLYALVVVHQAGSVSAAAPRVNLSQPALTQAVARLEQQLGVRLFDRHPGGMSATEAAGLLVPRIERVLAH
LGRGIGVARRALRLPARAGLERRVSLGQLQALVAVDVAGSYALAAVRAGVSQPAIYRAVQALADVIEVPLTVRRGKTMQP
TPVALRLLRQVRLALAELRAGLDEVAALRSQHAGRLTLGVMPLARAILLPQVLARFAHAHPGASVQVVEGPYEQLLAHLR
EGGLDLLIGALRDPLPVRDVLQEPLFDDEPVIVARSGHPLAGQGYAFAQLRDYPWVIAAAGTPVRARWEQLFGDHQLEPP
PVRIECGAELTVRGLLLEGDWLTLMSRDQFLFERRAGLLEEIGSAGPLLRRQIGMTTRSDWYPTRMQSAFVQTLRQVCAE
RVQPADAQGGPFRYCPAACAQPPLRLRAAKSESGS
>Mature_435_residues
MQPSPEPNLRHLYALVVVHQAGSVSAAAPRVNLSQPALTQAVARLEQQLGVRLFDRHPGGMSATEAAGLLVPRIERVLAH
LGRGIGVARRALRLPARAGLERRVSLGQLQALVAVDVAGSYALAAVRAGVSQPAIYRAVQALADVIEVPLTVRRGKTMQP
TPVALRLLRQVRLALAELRAGLDEVAALRSQHAGRLTLGVMPLARAILLPQVLARFAHAHPGASVQVVEGPYEQLLAHLR
EGGLDLLIGALRDPLPVRDVLQEPLFDDEPVIVARSGHPLAGQGYAFAQLRDYPWVIAAAGTPVRARWEQLFGDHQLEPP
PVRIECGAELTVRGLLLEGDWLTLMSRDQFLFERRAGLLEEIGSAGPLLRRQIGMTTRSDWYPTRMQSAFVQTLRQVCAE
RVQPADAQGGPFRYCPAACAQPPLRLRAAKSESGS

Specific function: Activates transcription of the pcaDCHGB operon for the catabolism of the phenolic compound protocatechuate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787601, Length=243, Percent_Identity=28.8065843621399, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI1789506, Length=233, Percent_Identity=24.4635193133047, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI87081904, Length=288, Percent_Identity=26.0416666666667, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788481, Length=270, Percent_Identity=25.9259259259259, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI157672245, Length=297, Percent_Identity=26.9360269360269, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788887, Length=297, Percent_Identity=26.9360269360269, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR012787
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 47120; Mature: 47120

Theoretical pI: Translated: 10.37; Mature: 10.37

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPSPEPNLRHLYALVVVHQAGSVSAAAPRVNLSQPALTQAVARLEQQLGVRLFDRHPGG
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCC
MSATEAAGLLVPRIERVLAHLGRGIGVARRALRLPARAGLERRVSLGQLQALVAVDVAGS
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHCHHHHHHHHHHHHHHHHHCCCH
YALAAVRAGVSQPAIYRAVQALADVIEVPLTVRRGKTMQPTPVALRLLRQVRLALAELRA
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
GLDEVAALRSQHAGRLTLGVMPLARAILLPQVLARFAHAHPGASVQVVEGPYEQLLAHLR
CHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHH
EGGLDLLIGALRDPLPVRDVLQEPLFDDEPVIVARSGHPLAGQGYAFAQLRDYPWVIAAA
HCCHHHHHHHHCCCCCHHHHHHCCCCCCCCEEEEECCCCCCCCCEEEEECCCCCEEEEEC
GTPVRARWEQLFGDHQLEPPPVRIECGAELTVRGLLLEGDWLTLMSRDQFLFERRAGLLE
CCCHHHHHHHHHCCCCCCCCCEEEECCCCEEEEEEEEECCEEEEHHHHHHHHHHHHHHHH
EIGSAGPLLRRQIGMTTRSDWYPTRMQSAFVQTLRQVCAERVQPADAQGGPFRYCPAACA
HHCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHC
QPPLRLRAAKSESGS
CCCCEEEECCCCCCC
>Mature Secondary Structure
MQPSPEPNLRHLYALVVVHQAGSVSAAAPRVNLSQPALTQAVARLEQQLGVRLFDRHPGG
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCC
MSATEAAGLLVPRIERVLAHLGRGIGVARRALRLPARAGLERRVSLGQLQALVAVDVAGS
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHCHHHHHHHHHHHHHHHHHCCCH
YALAAVRAGVSQPAIYRAVQALADVIEVPLTVRRGKTMQPTPVALRLLRQVRLALAELRA
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
GLDEVAALRSQHAGRLTLGVMPLARAILLPQVLARFAHAHPGASVQVVEGPYEQLLAHLR
CHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHH
EGGLDLLIGALRDPLPVRDVLQEPLFDDEPVIVARSGHPLAGQGYAFAQLRDYPWVIAAA
HCCHHHHHHHHCCCCCHHHHHHCCCCCCCCEEEEECCCCCCCCCEEEEECCCCCEEEEEC
GTPVRARWEQLFGDHQLEPPPVRIECGAELTVRGLLLEGDWLTLMSRDQFLFERRAGLLE
CCCHHHHHHHHHCCCCCCCCCEEEECCCCEEEEEEEEECCEEEEHHHHHHHHHHHHHHHH
EIGSAGPLLRRQIGMTTRSDWYPTRMQSAFVQTLRQVCAERVQPADAQGGPFRYCPAACA
HHCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHC
QPPLRLRAAKSESGS
CCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]