Click here to switch to the map view.

The map label for this gene is entF [H]

Identifier: 21244641

GI number: 21244641

Start: 4608476

End: 4612474

Strand: Reverse

Name: entF [H]

Synonym: XAC3922

Alternate gene names: 21244641

Gene position: 4612474-4608476 (Counterclockwise)

Preceding gene: 77748748

Following gene: 21244640

Centisome position: 89.12

GC content: 65.79

Gene sequence:

>3999_bases
ATGCACGCTGACGCCTCTCCCGTTTTTCCCCTGACCAAGGCGCAACGTGGCCTTTGGGTGGCCAACAAGTTGCACACCGA
CAATACCTTGATGTTGGCCGAAGTACTGGAAATGTTCGGCCCGCTCAATCCCCAGGTGCTGATCCGCGCCAGCATGCAGC
TGACGCACGAGTTCGATACGCTGCGCCTGTGTATCGTCGAGCGCGAGGGCGTGCCTTCGCAGGTGGTCTTGCCCGAGTAC
AACGGCACGATTCCATACTTCGACGTCAGCTCAGATCCTGCTCCGCGTAATGCCGCCGAACATTGGATCGACGAAGAAAT
CCGCAAGCCGGAAGATCTGCAGAACGGACCGCTGTGGCATTGCGCGGTGTTCCGTCTTGGCGAAGATCATCATCTATGGG
TGCAATGTGTGAGCCATCTGGTGATGGACGGCTATTGCGCGTCGGTCATGATGCAGCGCATGGCCGTGCTCTATAACGCC
TACGTGGCCGACATGGAGCCGGAGCCTGCGCAGTACGGTAGTGCACTGTCGCTGCTCGAAATGGAACAGCACTATCGCAA
CTCCGATCGGTTCCAGCGCGATCGCGAATACTGGATGCAGCAGTTGGCCGATCTGCCGCCGCCGGCGACGCTGGCGCGGC
CGGGCAATCAGCTGTCCACCGGGCTATTGCGTGGCACCGGGCAGTTCTCGCCGCAGCAGGTGGTGCGTTTGCGCGCGCTG
GGCAAGGAGTACGGCGCCAGCCTGCCGCAGATGCTGATTTCGCTGATCGCGGCGTACTACTACCGCTGCACCGGTGCCGA
GGACCTGGTGCTGGCGATGCCGGTCACCGGCCGCATCAACGCGCGCTACCGGCAAACCGCAGGCCTGGTGGCCAACGTCA
TTTCACTGCGCCTGAAGATGGATCCGCAGCAGCCCATCCATACCTTGTTCGCGCAGGTATCCTCGGTGGTGCGGAACGCC
TTGCGCCATCAGCAATATCGCTTCGAGGACGTGCGCCGCGATCTGGGCATGTTCGGGATGGAGCAGAAGTTCGCACGCCT
GGCGGTGAACATCGAGCCCTTCGACTACGCCTTGCGCTTCGGCGAGGCGTACGCGGTGCCGCACAACCTTTCCAACGGCC
CGGCCGACGACCTCACCATCTTCTGCTACGAACGCGGCGATGGGGCAGCGGTGCGTTTCGATCTGGATGCCAACCCGGCG
TTATACGACAGCGACGAACTGGCCGAACACTGCCGCCGTCTGACCCATCTGGCCGATGCGGTACTGGCCGATCCGGAATG
CGCGCTGGGCCAGGTCGATGTGCTCGGCGATAGCGAGCGCCGGCGTTTGCTGCACACCTGGAACAACACCGCAGCGCCGC
TGCCGGAGCCGGCCACGCTGTTGCACGGGATGCTGCAACGCGCCGAGTTGATGCCTGCGGCCGTGGTGGCGCAATACGAC
AACCGCACGCTCGACTATGCCACGTTGTGCGAACTTGCCTCGCGCATCGCCGCGCAATGGGTGGCCGATGGCGTGGGCCC
TGGCGATGTGGTCGCGGTGGCGCTGCCGCGCAGCGAACAATTGTTGGTGGCGTTGCTGGCGGTGATGTGGAGCGGTGCGG
CGTACCTGCCGCTGGATCCGGAGAGCCCGGCCGCGCGCAACCGCCAGATGCTCAACGATTCCGGTGCCACCGGCCTGGTC
TGCGAGCCGGCACTGTGCGAGCGCTATCTGCTCGATGGCATGGTCTGGCTGGATCCGCGCCCGGCCGTGTTGCCGGAGGC
GATCGCACCGCTGGCGACGCCCGACGGCACCGCGTACGTGCTGTACACCTCCGGCTCCACCGGTGCGCCCAAGGGCGTGG
AGATCAGCCATCGCAACCTGTTCAATTTCCTGCATGCGATGGAGCACGAGCTGGCATTGCGTCCGCGCGATCGTGTGCTG
GCAGTCACCACCATCACCTTCGATATCGCCGGGCTGGAGCTGTACCTGCCGTTGCTGGTGGGCGCGCGCGTGGTCATTGC
ACCGGCCGGTATCAGCCACGACCCGCGCGGCCTGTCGCGGTTGATCGCCGACGAACACATCAGCGTGGTGCAGGCCACGC
CATCGCTGTGGCGCATCCTGCTGGCCAATGAGGATCTGGTGCTGGATCGCATCCACGCGCTGATCGGCGGCGAGGCGTTG
GTGCCGGAACTGGCCACGCAATTGCTCAGCCGGGTGGGGCGCCTGACCCAGTTGTACGGGCCCACCGAAACCACGATCTG
GTCGACCATCATGCCGTTGCAGCTGACCGATGCCGCCGCACCGCCGATCGGCAGGCCGCTGCTCAATACGCGCGTCTATG
TGCTGGATGCGCAGCGTCAACCGCTGCCGACCGGTGCGATCGGCGAGCTGTATATCGGCGGCGCGGGCGTGGCCAAGGGC
TATCGCGGCAAGCGCCAGCTGACCAGCGAGCGTTTCATGCGCGACCCGTTCGCCGACGACGGCAGCAGCATGTACCGCAC
CGGCGACCGCGTGCGTCAACGCAGCGATGGCCTGCTGGAATTCATCGGGCGCGCCGATGCGCAGCTGAAGATCCGCGGAC
ATCGGGTGGAGCCGGCCGAAATCGAAAGCGCCTTGCTGCTGCATTCGCAGGTGGCGCAGGCGGTGGTGGTGGGCCACAGC
GATGGCGAGCATGCCTTGCAGCTGCTGGCTTATGTGGTGGGCAAGCACGGCAACGCGCCATCGGTCGAGCTGCTACGCGC
GCATCTGCAGCAGCGCCTGCCGGCATCGATGATTCCTACCCTGTGGGTGCCGCTGGAGGCGTTGCCGCTGACCCCCAACG
GCAAGCTGGATCGGCGCGCATTACCGGCGCCTGGCGCCTTGCCGCAACGCGCGCACCTGGCGCCGCGCGATGCGCTCGAA
CGCCAGTTGGCAACGATGCTGCAGGAGGTGCTGGGCATCGAGGTGGTGGGCGTAGACGACAACTTCTTCGAGCTTGGCGG
CGATTCGCTGCGTGCGGCGGAAATGACCGCGCGTTTCCCGCAGATGTTCGGGGTGGAACTGCCGCTGGGCACGTTGTTCC
ATGCACCGACGATCGCCGGCCTGGCCGAGGTGATCAAGCGCAGCGCACACACGCCCAACGACCCGTTGAGCGTGCTGCTG
CCGCTGCGCGCCGGCACCGCCGGCACCACGCCGCTGTTCTGCATCCATCCGGTCATCGGCCTGGGCTGGTCGTATCTCAC
CTTGCTGGGTCAGCTGGATCCGCAGTGGCCGGTGTATGCGCTGCAATCGCCGGGCTTGAGCGACCCGCAGCACCGTCCGG
AGAGCATCGAGGCGATCGCGCGCGATTACCTGGCGCATCTGCGCAGCGTGCAACCCAAGGGGCCGTACCGTCTGCTGGGC
TGGTCGCTGGGCGGTTTGATCGCGCACGCCATCACGGCCGAATTGCATGCGCTGGGCGAAGAGGTCGAGTTGCTGGTCAT
GCTCGACAGTTACCCGCATCTGGAACAGGCCGCATCGCTGTCGGAATCGGAGAACGTACGCGCCTCGGTGCACGCGTTGG
CCCTGCATCTGGCGCCGGGCCAGCCGATGCCGACCACGGTCGCCGAGCTTGCCAGCCTGTTGTGCGATCACTACGGGCTG
AACGAGTTGCCTGCGGTGCGGCAGTTGCTGGAGCAACGTCCCACCTTGCTGGACGATCTGGGCGCCCTCACCCAGCATCA
CCTGCACCTGGCGCGGCGTCATCGGCCCAGGCAGCTGGACCAGGATGTGGTCTTTGTCGAAGCGAGCGTGCGCATGAGCT
CCGGCGGCGACGATGCGCTGTGGGTGGATTACCGTCCCCAGGCGTGGCACCCGTACGTGCGCAACCTGCAGCTGCACGCT
CTGGACAGCGACCACCATTCGATGCTCTCGCCGACGCATTCGGCCACGCTCAGCACCTTGCTGCACGCGGCCACCGCAGA
GGCCGCGCGGGCTGAACAGCCTGTAGGGCAGACCGGCCGTAGTGCGGTCGCCGGCGACGGAGTGACCGAATATGCCTGA

Upstream 100 bases:

>100_bases
CCCTCGTTTCTTAAGGCCAGATGCTGATTCGGCGTCCATTGACCGCATAACGGTTGGGGGGCGTCGACGGACTGCGCGCC
ACATCAGAAGGATGCACGCA

Downstream 100 bases:

>100_bases
GTCCAGAGCCGATCCGTTACGCCAGCGCCCGGTGGTGATCGCCACCCTTGGCACGCATGGGGACGTGCGCCCGATCATTG
CGCTGGCGCTTGGCCTGCAG

Product: ATP-dependent serine activating enzyme

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: NA

Number of amino acids: Translated: 1332; Mature: 1332

Protein sequence:

>1332_residues
MHADASPVFPLTKAQRGLWVANKLHTDNTLMLAEVLEMFGPLNPQVLIRASMQLTHEFDTLRLCIVEREGVPSQVVLPEY
NGTIPYFDVSSDPAPRNAAEHWIDEEIRKPEDLQNGPLWHCAVFRLGEDHHLWVQCVSHLVMDGYCASVMMQRMAVLYNA
YVADMEPEPAQYGSALSLLEMEQHYRNSDRFQRDREYWMQQLADLPPPATLARPGNQLSTGLLRGTGQFSPQQVVRLRAL
GKEYGASLPQMLISLIAAYYYRCTGAEDLVLAMPVTGRINARYRQTAGLVANVISLRLKMDPQQPIHTLFAQVSSVVRNA
LRHQQYRFEDVRRDLGMFGMEQKFARLAVNIEPFDYALRFGEAYAVPHNLSNGPADDLTIFCYERGDGAAVRFDLDANPA
LYDSDELAEHCRRLTHLADAVLADPECALGQVDVLGDSERRRLLHTWNNTAAPLPEPATLLHGMLQRAELMPAAVVAQYD
NRTLDYATLCELASRIAAQWVADGVGPGDVVAVALPRSEQLLVALLAVMWSGAAYLPLDPESPAARNRQMLNDSGATGLV
CEPALCERYLLDGMVWLDPRPAVLPEAIAPLATPDGTAYVLYTSGSTGAPKGVEISHRNLFNFLHAMEHELALRPRDRVL
AVTTITFDIAGLELYLPLLVGARVVIAPAGISHDPRGLSRLIADEHISVVQATPSLWRILLANEDLVLDRIHALIGGEAL
VPELATQLLSRVGRLTQLYGPTETTIWSTIMPLQLTDAAAPPIGRPLLNTRVYVLDAQRQPLPTGAIGELYIGGAGVAKG
YRGKRQLTSERFMRDPFADDGSSMYRTGDRVRQRSDGLLEFIGRADAQLKIRGHRVEPAEIESALLLHSQVAQAVVVGHS
DGEHALQLLAYVVGKHGNAPSVELLRAHLQQRLPASMIPTLWVPLEALPLTPNGKLDRRALPAPGALPQRAHLAPRDALE
RQLATMLQEVLGIEVVGVDDNFFELGGDSLRAAEMTARFPQMFGVELPLGTLFHAPTIAGLAEVIKRSAHTPNDPLSVLL
PLRAGTAGTTPLFCIHPVIGLGWSYLTLLGQLDPQWPVYALQSPGLSDPQHRPESIEAIARDYLAHLRSVQPKGPYRLLG
WSLGGLIAHAITAELHALGEEVELLVMLDSYPHLEQAASLSESENVRASVHALALHLAPGQPMPTTVAELASLLCDHYGL
NELPAVRQLLEQRPTLLDDLGALTQHHLHLARRHRPRQLDQDVVFVEASVRMSSGGDDALWVDYRPQAWHPYVRNLQLHA
LDSDHHSMLSPTHSATLSTLLHAATAEAARAEQPVGQTGRSAVAGDGVTEYA

Sequences:

>Translated_1332_residues
MHADASPVFPLTKAQRGLWVANKLHTDNTLMLAEVLEMFGPLNPQVLIRASMQLTHEFDTLRLCIVEREGVPSQVVLPEY
NGTIPYFDVSSDPAPRNAAEHWIDEEIRKPEDLQNGPLWHCAVFRLGEDHHLWVQCVSHLVMDGYCASVMMQRMAVLYNA
YVADMEPEPAQYGSALSLLEMEQHYRNSDRFQRDREYWMQQLADLPPPATLARPGNQLSTGLLRGTGQFSPQQVVRLRAL
GKEYGASLPQMLISLIAAYYYRCTGAEDLVLAMPVTGRINARYRQTAGLVANVISLRLKMDPQQPIHTLFAQVSSVVRNA
LRHQQYRFEDVRRDLGMFGMEQKFARLAVNIEPFDYALRFGEAYAVPHNLSNGPADDLTIFCYERGDGAAVRFDLDANPA
LYDSDELAEHCRRLTHLADAVLADPECALGQVDVLGDSERRRLLHTWNNTAAPLPEPATLLHGMLQRAELMPAAVVAQYD
NRTLDYATLCELASRIAAQWVADGVGPGDVVAVALPRSEQLLVALLAVMWSGAAYLPLDPESPAARNRQMLNDSGATGLV
CEPALCERYLLDGMVWLDPRPAVLPEAIAPLATPDGTAYVLYTSGSTGAPKGVEISHRNLFNFLHAMEHELALRPRDRVL
AVTTITFDIAGLELYLPLLVGARVVIAPAGISHDPRGLSRLIADEHISVVQATPSLWRILLANEDLVLDRIHALIGGEAL
VPELATQLLSRVGRLTQLYGPTETTIWSTIMPLQLTDAAAPPIGRPLLNTRVYVLDAQRQPLPTGAIGELYIGGAGVAKG
YRGKRQLTSERFMRDPFADDGSSMYRTGDRVRQRSDGLLEFIGRADAQLKIRGHRVEPAEIESALLLHSQVAQAVVVGHS
DGEHALQLLAYVVGKHGNAPSVELLRAHLQQRLPASMIPTLWVPLEALPLTPNGKLDRRALPAPGALPQRAHLAPRDALE
RQLATMLQEVLGIEVVGVDDNFFELGGDSLRAAEMTARFPQMFGVELPLGTLFHAPTIAGLAEVIKRSAHTPNDPLSVLL
PLRAGTAGTTPLFCIHPVIGLGWSYLTLLGQLDPQWPVYALQSPGLSDPQHRPESIEAIARDYLAHLRSVQPKGPYRLLG
WSLGGLIAHAITAELHALGEEVELLVMLDSYPHLEQAASLSESENVRASVHALALHLAPGQPMPTTVAELASLLCDHYGL
NELPAVRQLLEQRPTLLDDLGALTQHHLHLARRHRPRQLDQDVVFVEASVRMSSGGDDALWVDYRPQAWHPYVRNLQLHA
LDSDHHSMLSPTHSATLSTLLHAATAEAARAEQPVGQTGRSAVAGDGVTEYA
>Mature_1332_residues
MHADASPVFPLTKAQRGLWVANKLHTDNTLMLAEVLEMFGPLNPQVLIRASMQLTHEFDTLRLCIVEREGVPSQVVLPEY
NGTIPYFDVSSDPAPRNAAEHWIDEEIRKPEDLQNGPLWHCAVFRLGEDHHLWVQCVSHLVMDGYCASVMMQRMAVLYNA
YVADMEPEPAQYGSALSLLEMEQHYRNSDRFQRDREYWMQQLADLPPPATLARPGNQLSTGLLRGTGQFSPQQVVRLRAL
GKEYGASLPQMLISLIAAYYYRCTGAEDLVLAMPVTGRINARYRQTAGLVANVISLRLKMDPQQPIHTLFAQVSSVVRNA
LRHQQYRFEDVRRDLGMFGMEQKFARLAVNIEPFDYALRFGEAYAVPHNLSNGPADDLTIFCYERGDGAAVRFDLDANPA
LYDSDELAEHCRRLTHLADAVLADPECALGQVDVLGDSERRRLLHTWNNTAAPLPEPATLLHGMLQRAELMPAAVVAQYD
NRTLDYATLCELASRIAAQWVADGVGPGDVVAVALPRSEQLLVALLAVMWSGAAYLPLDPESPAARNRQMLNDSGATGLV
CEPALCERYLLDGMVWLDPRPAVLPEAIAPLATPDGTAYVLYTSGSTGAPKGVEISHRNLFNFLHAMEHELALRPRDRVL
AVTTITFDIAGLELYLPLLVGARVVIAPAGISHDPRGLSRLIADEHISVVQATPSLWRILLANEDLVLDRIHALIGGEAL
VPELATQLLSRVGRLTQLYGPTETTIWSTIMPLQLTDAAAPPIGRPLLNTRVYVLDAQRQPLPTGAIGELYIGGAGVAKG
YRGKRQLTSERFMRDPFADDGSSMYRTGDRVRQRSDGLLEFIGRADAQLKIRGHRVEPAEIESALLLHSQVAQAVVVGHS
DGEHALQLLAYVVGKHGNAPSVELLRAHLQQRLPASMIPTLWVPLEALPLTPNGKLDRRALPAPGALPQRAHLAPRDALE
RQLATMLQEVLGIEVVGVDDNFFELGGDSLRAAEMTARFPQMFGVELPLGTLFHAPTIAGLAEVIKRSAHTPNDPLSVLL
PLRAGTAGTTPLFCIHPVIGLGWSYLTLLGQLDPQWPVYALQSPGLSDPQHRPESIEAIARDYLAHLRSVQPKGPYRLLG
WSLGGLIAHAITAELHALGEEVELLVMLDSYPHLEQAASLSESENVRASVHALALHLAPGQPMPTTVAELASLLCDHYGL
NELPAVRQLLEQRPTLLDDLGALTQHHLHLARRHRPRQLDQDVVFVEASVRMSSGGDDALWVDYRPQAWHPYVRNLQLHA
LDSDHHSMLSPTHSATLSTLLHAATAEAARAEQPVGQTGRSAVAGDGVTEYA

Specific function: Specifically adenylates threonine and glycine, and loads them onto their corresponding peptidyl carrier domains [H]

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 acyl carrier domain [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=463, Percent_Identity=28.0777537796976, Blast_Score=130, Evalue=6e-30,
Organism=Homo sapiens, GI156151445, Length=525, Percent_Identity=24, Blast_Score=103, Evalue=2e-21,
Organism=Homo sapiens, GI115511026, Length=515, Percent_Identity=24.6601941747573, Blast_Score=93, Evalue=1e-18,
Organism=Homo sapiens, GI38505220, Length=481, Percent_Identity=25.3638253638254, Blast_Score=91, Evalue=1e-17,
Organism=Homo sapiens, GI187761345, Length=478, Percent_Identity=25.3138075313808, Blast_Score=89, Evalue=3e-17,
Organism=Homo sapiens, GI187761343, Length=478, Percent_Identity=25.3138075313808, Blast_Score=89, Evalue=3e-17,
Organism=Homo sapiens, GI122937307, Length=359, Percent_Identity=27.0194986072423, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI157311624, Length=478, Percent_Identity=23.8493723849372, Blast_Score=84, Evalue=1e-15,
Organism=Homo sapiens, GI157311622, Length=478, Percent_Identity=23.8493723849372, Blast_Score=84, Evalue=1e-15,
Organism=Homo sapiens, GI42544132, Length=360, Percent_Identity=24.1666666666667, Blast_Score=80, Evalue=1e-14,
Organism=Homo sapiens, GI58082049, Length=482, Percent_Identity=24.0663900414938, Blast_Score=80, Evalue=2e-14,
Organism=Escherichia coli, GI1786801, Length=1193, Percent_Identity=31.4333612740989, Blast_Score=485, Evalue=1e-138,
Organism=Escherichia coli, GI1790505, Length=367, Percent_Identity=28.8828337874659, Blast_Score=110, Evalue=5e-25,
Organism=Escherichia coli, GI145693145, Length=532, Percent_Identity=26.6917293233083, Blast_Score=104, Evalue=4e-23,
Organism=Escherichia coli, GI1788107, Length=514, Percent_Identity=24.124513618677, Blast_Score=98, Evalue=3e-21,
Organism=Escherichia coli, GI221142682, Length=490, Percent_Identity=24.8979591836735, Blast_Score=97, Evalue=6e-21,
Organism=Escherichia coli, GI1786810, Length=518, Percent_Identity=24.9034749034749, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17550940, Length=1047, Percent_Identity=22.3495702005731, Blast_Score=167, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI17556356, Length=555, Percent_Identity=25.9459459459459, Blast_Score=163, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI32564420, Length=416, Percent_Identity=24.0384615384615, Blast_Score=100, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI32564422, Length=416, Percent_Identity=24.0384615384615, Blast_Score=100, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17557194, Length=500, Percent_Identity=24.4, Blast_Score=95, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17531443, Length=523, Percent_Identity=25.0478011472275, Blast_Score=94, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17538037, Length=510, Percent_Identity=24.5098039215686, Blast_Score=92, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17560308, Length=360, Percent_Identity=24.7222222222222, Blast_Score=87, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71982997, Length=542, Percent_Identity=26.9372693726937, Blast_Score=84, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71983001, Length=542, Percent_Identity=26.9372693726937, Blast_Score=84, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71994690, Length=364, Percent_Identity=21.978021978022, Blast_Score=79, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71994694, Length=364, Percent_Identity=21.978021978022, Blast_Score=79, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71994703, Length=364, Percent_Identity=21.978021978022, Blast_Score=78, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17559526, Length=362, Percent_Identity=24.0331491712707, Blast_Score=69, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319591, Length=957, Percent_Identity=24.0334378265413, Blast_Score=214, Evalue=7e-56,
Organism=Saccharomyces cerevisiae, GI6319699, Length=393, Percent_Identity=24.9363867684478, Blast_Score=94, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6319264, Length=374, Percent_Identity=25.1336898395722, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24648676, Length=604, Percent_Identity=30.6291390728477, Blast_Score=195, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24581924, Length=525, Percent_Identity=24, Blast_Score=116, Evalue=1e-25,
Organism=Drosophila melanogaster, GI21355181, Length=484, Percent_Identity=25.8264462809917, Blast_Score=87, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24582852, Length=376, Percent_Identity=24.468085106383, Blast_Score=75, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24653035, Length=503, Percent_Identity=22.6640159045726, Blast_Score=73, Evalue=1e-12,
Organism=Drosophila melanogaster, GI18859661, Length=363, Percent_Identity=23.1404958677686, Blast_Score=70, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding; PF00975 Thioesterase [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 146299; Mature: 146299

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHADASPVFPLTKAQRGLWVANKLHTDNTLMLAEVLEMFGPLNPQVLIRASMQLTHEFDT
CCCCCCCCCCHHHHCCCEEEEHEECCCCHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHCE
LRLCIVEREGVPSQVVLPEYNGTIPYFDVSSDPAPRNAAEHWIDEEIRKPEDLQNGPLWH
EEEEEEECCCCCCEEEEECCCCCCCEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEE
CAVFRLGEDHHLWVQCVSHLVMDGYCASVMMQRMAVLYNAYVADMEPEPAQYGSALSLLE
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
MEQHYRNSDRFQRDREYWMQQLADLPPPATLARPGNQLSTGLLRGTGQFSPQQVVRLRAL
HHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHH
GKEYGASLPQMLISLIAAYYYRCTGAEDLVLAMPVTGRINARYRQTAGLVANVISLRLKM
HHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHEEC
DPQQPIHTLFAQVSSVVRNALRHQQYRFEDVRRDLGMFGMEQKFARLAVNIEPFDYALRF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHEECCCCHHHHHHH
GEAYAVPHNLSNGPADDLTIFCYERGDGAAVRFDLDANPALYDSDELAEHCRRLTHLADA
CCEEECCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
VLADPECALGQVDVLGDSERRRLLHTWNNTAAPLPEPATLLHGMLQRAELMPAAVVAQYD
HHCCCCCCCCCEEECCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHCC
NRTLDYATLCELASRIAAQWVADGVGPGDVVAVALPRSEQLLVALLAVMWSGAAYLPLDP
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEECCCC
ESPAARNRQMLNDSGATGLVCEPALCERYLLDGMVWLDPRPAVLPEAIAPLATPDGTAYV
CCCCHHHHHHHCCCCCCCEEECHHHHHHHHHCCEEEECCCCCCCHHHHCCCCCCCCCEEE
LYTSGSTGAPKGVEISHRNLFNFLHAMEHELALRPRDRVLAVTTITFDIAGLELYLPLLV
EEECCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEHHHHHHHHHHHH
GARVVIAPAGISHDPRGLSRLIADEHISVVQATPSLWRILLANEDLVLDRIHALIGGEAL
CCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHCCCHH
VPELATQLLSRVGRLTQLYGPTETTIWSTIMPLQLTDAAAPPIGRPLLNTRVYVLDAQRQ
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCEEECCCCCCCCCCCHHCCEEEEEECCCC
PLPTGAIGELYIGGAGVAKGYRGKRQLTSERFMRDPFADDGSSMYRTGDRVRQRSDGLLE
CCCCCCCCCEEECCCHHHCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCHHHH
FIGRADAQLKIRGHRVEPAEIESALLLHSQVAQAVVVGHSDGEHALQLLAYVVGKHGNAP
HHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHCCCCCC
SVELLRAHLQQRLPASMIPTLWVPLEALPLTPNGKLDRRALPAPGALPQRAHLAPRDALE
HHHHHHHHHHHCCCHHHCCHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
RQLATMLQEVLGIEVVGVDDNFFELGGDSLRAAEMTARFPQMFGVELPLGTLFHAPTIAG
HHHHHHHHHHHCEEEEECCCCHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHCHHHHH
LAEVIKRSAHTPNDPLSVLLPLRAGTAGTTPLFCIHPVIGLGWSYLTLLGQLDPQWPVYA
HHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHCCHHHHHHHHCCCCCCCEEE
LQSPGLSDPQHRPESIEAIARDYLAHLRSVQPKGPYRLLGWSLGGLIAHAITAELHALGE
ECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCC
EVELLVMLDSYPHLEQAASLSESENVRASVHALALHLAPGQPMPTTVAELASLLCDHYGL
CEEEEEEECCCCCHHHHHCCCCCCCHHHEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCC
NELPAVRQLLEQRPTLLDDLGALTQHHLHLARRHRPRQLDQDVVFVEASVRMSSGGDDAL
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCCCCEE
WVDYRPQAWHPYVRNLQLHALDSDHHSMLSPTHSATLSTLLHAATAEAARAEQPVGQTGR
EEECCCCCCCHHHHCEEEEEECCCCHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SAVAGDGVTEYA
CCCCCCCCCCCC
>Mature Secondary Structure
MHADASPVFPLTKAQRGLWVANKLHTDNTLMLAEVLEMFGPLNPQVLIRASMQLTHEFDT
CCCCCCCCCCHHHHCCCEEEEHEECCCCHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHCE
LRLCIVEREGVPSQVVLPEYNGTIPYFDVSSDPAPRNAAEHWIDEEIRKPEDLQNGPLWH
EEEEEEECCCCCCEEEEECCCCCCCEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEE
CAVFRLGEDHHLWVQCVSHLVMDGYCASVMMQRMAVLYNAYVADMEPEPAQYGSALSLLE
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
MEQHYRNSDRFQRDREYWMQQLADLPPPATLARPGNQLSTGLLRGTGQFSPQQVVRLRAL
HHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHH
GKEYGASLPQMLISLIAAYYYRCTGAEDLVLAMPVTGRINARYRQTAGLVANVISLRLKM
HHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHEEC
DPQQPIHTLFAQVSSVVRNALRHQQYRFEDVRRDLGMFGMEQKFARLAVNIEPFDYALRF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHEECCCCHHHHHHH
GEAYAVPHNLSNGPADDLTIFCYERGDGAAVRFDLDANPALYDSDELAEHCRRLTHLADA
CCEEECCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
VLADPECALGQVDVLGDSERRRLLHTWNNTAAPLPEPATLLHGMLQRAELMPAAVVAQYD
HHCCCCCCCCCEEECCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHCC
NRTLDYATLCELASRIAAQWVADGVGPGDVVAVALPRSEQLLVALLAVMWSGAAYLPLDP
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEECCCC
ESPAARNRQMLNDSGATGLVCEPALCERYLLDGMVWLDPRPAVLPEAIAPLATPDGTAYV
CCCCHHHHHHHCCCCCCCEEECHHHHHHHHHCCEEEECCCCCCCHHHHCCCCCCCCCEEE
LYTSGSTGAPKGVEISHRNLFNFLHAMEHELALRPRDRVLAVTTITFDIAGLELYLPLLV
EEECCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEHHHHHHHHHHHH
GARVVIAPAGISHDPRGLSRLIADEHISVVQATPSLWRILLANEDLVLDRIHALIGGEAL
CCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHCCCHH
VPELATQLLSRVGRLTQLYGPTETTIWSTIMPLQLTDAAAPPIGRPLLNTRVYVLDAQRQ
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCEEECCCCCCCCCCCHHCCEEEEEECCCC
PLPTGAIGELYIGGAGVAKGYRGKRQLTSERFMRDPFADDGSSMYRTGDRVRQRSDGLLE
CCCCCCCCCEEECCCHHHCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCHHHH
FIGRADAQLKIRGHRVEPAEIESALLLHSQVAQAVVVGHSDGEHALQLLAYVVGKHGNAP
HHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHCCCCCC
SVELLRAHLQQRLPASMIPTLWVPLEALPLTPNGKLDRRALPAPGALPQRAHLAPRDALE
HHHHHHHHHHHCCCHHHCCHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
RQLATMLQEVLGIEVVGVDDNFFELGGDSLRAAEMTARFPQMFGVELPLGTLFHAPTIAG
HHHHHHHHHHHCEEEEECCCCHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHCHHHHH
LAEVIKRSAHTPNDPLSVLLPLRAGTAGTTPLFCIHPVIGLGWSYLTLLGQLDPQWPVYA
HHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHCCHHHHHHHHCCCCCCCEEE
LQSPGLSDPQHRPESIEAIARDYLAHLRSVQPKGPYRLLGWSLGGLIAHAITAELHALGE
ECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCC
EVELLVMLDSYPHLEQAASLSESENVRASVHALALHLAPGQPMPTTVAELASLLCDHYGL
CEEEEEEECCCCCHHHHHCCCCCCCHHHEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCC
NELPAVRQLLEQRPTLLDDLGALTQHHLHLARRHRPRQLDQDVVFVEASVRMSSGGDDAL
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCCCCEE
WVDYRPQAWHPYVRNLQLHALDSDHHSMLSPTHSATLSTLLHAATAEAARAEQPVGQTGR
EEECCCCCCCHHHHCEEEEEECCCCHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SAVAGDGVTEYA
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11112781; 9384377; 10568751; 8550523 [H]