BacMap

Definition	Xanthomonas axonopodis pv. citri str. 306 chromosome, complete genome.
Accession	NC_003919
Length	5,175,554

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The map label for this gene is sdh [H]

Identifier: 21244638

GI number: 21244638

Start: 4604976

End: 4605731

Strand: Direct

Name: sdh [H]

Synonym: XAC3919

Alternate gene names: 21244638

Gene position: 4604976-4605731 (Clockwise)

Preceding gene: 21244637

Following gene: 21244643

Centisome position: 88.98

GC content: 67.33

Gene sequence:

>756_bases
ATGTCCAAGACCGTCCTGATCACTGGTGCTACCTCCGGATTCGGCAGCGCCGCCGTGCGCCGCTTCGCTGCAGCCGGCTG
GAAGGTCATCGCCACCGGCCGGCGCGCCGAACGCCTGCAGGCGCTGGCCGCTGAACTGCCGGCCGGGCAGGTCCACACCG
CCGCGTTCGACATGCGCGATGCACGCGCCTTGTCGGACGCGATCGACGCAGTGCCGGCCGCATTCGCCGATATCGACGTG
CTGGTCAACAACGCCGGCCTGGCGCTGGGCACCGCACCGGCGCAGCAGGCCGACCTGGCGCAGTGGCAGCAGATGATCGA
CACCAATGTCACTGCGCTGGTCACGCTCACCCACCGCCTGCTGCCGGCGTTGATCGCGCGCCGCGGCGCCATCATCAACA
TCGCCTCGGTCGCGGCAACCTACCCATATACCGGCGGCAACGTCTACGGCGGTACCAAGGCCTTCGTGCAGCAGTTTTCG
CTGGGCCTGCGCTCTGATCTGCACGGCACCGGCGTGCGCGTGACCTCGATCGAACCGGGCATGGCCGAGACCGAATTCAC
CCTGGTGCGCACCGGGGGCAACCAGGCGGCGTCGGATACGCTATACCGTGGCGCCACCCCGATGACGGCAGAAGACATCG
CCGAACAGATCTTCTATGTCGCCAGCCTGCCGGCGCATTTGAATATCAACCGCCTGGAAATCATGCCGGTGACCCAGTCC
TTTGCGGGGTTCCAGGTGGCGCGCGACGCGCAGTGA

Upstream 100 bases:

>100_bases
CTGACCGAACAGCTGCTGCGTGCACGGCATGCCGCAATGGCGAACCCGCGGCCTGCTCACTGAATCTGGTTCCCGCCCCC
CTGTCCTCCTGGAGTTCCTC

Downstream 100 bases:

>100_bases
GGCGTTGCACTGAAGCCAGGGCTGGGGCGGTGCGCGCGCAGTGCGCCAGCCATACATCCCGCTGCGCCGCGTAGCCCTAC
CGAGTATCGAAAAGCCGCGC

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MSKTVLITGATSGFGSAAVRRFAAAGWKVIATGRRAERLQALAAELPAGQVHTAAFDMRDARALSDAIDAVPAAFADIDV
LVNNAGLALGTAPAQQADLAQWQQMIDTNVTALVTLTHRLLPALIARRGAIINIASVAATYPYTGGNVYGGTKAFVQQFS
LGLRSDLHGTGVRVTSIEPGMAETEFTLVRTGGNQAASDTLYRGATPMTAEDIAEQIFYVASLPAHLNINRLEIMPVTQS
FAGFQVARDAQ

Sequences:

>Translated_251_residues
MSKTVLITGATSGFGSAAVRRFAAAGWKVIATGRRAERLQALAAELPAGQVHTAAFDMRDARALSDAIDAVPAAFADIDV
LVNNAGLALGTAPAQQADLAQWQQMIDTNVTALVTLTHRLLPALIARRGAIINIASVAATYPYTGGNVYGGTKAFVQQFS
LGLRSDLHGTGVRVTSIEPGMAETEFTLVRTGGNQAASDTLYRGATPMTAEDIAEQIFYVASLPAHLNINRLEIMPVTQS
FAGFQVARDAQ
>Mature_250_residues
SKTVLITGATSGFGSAAVRRFAAAGWKVIATGRRAERLQALAAELPAGQVHTAAFDMRDARALSDAIDAVPAAFADIDVL
VNNAGLALGTAPAQQADLAQWQQMIDTNVTALVTLTHRLLPALIARRGAIINIASVAATYPYTGGNVYGGTKAFVQQFSL
GLRSDLHGTGVRVTSIEPGMAETEFTLVRTGGNQAASDTLYRGATPMTAEDIAEQIFYVASLPAHLNINRLEIMPVTQSF
AGFQVARDAQ

Specific function: Catalyzes the oxidation of the hydroxyl group of serine to form 2-aminomalonate semialdehyde which is spontaneously converted into 2-aminoacetaldehyde and CO(2). Also acts on D- serine, L-glycerate, D-glycerate and 2-methyl-DL-serine. Does not act on O-me

COG id: COG4221

COG function: function code R; Short-chain alcohol dehydrogenase of unknown specificity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI109715829, Length=245, Percent_Identity=29.3877551020408, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI20149619, Length=194, Percent_Identity=34.020618556701, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI40548397, Length=187, Percent_Identity=31.5508021390374, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI214010158, Length=187, Percent_Identity=31.5508021390374, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI214010156, Length=187, Percent_Identity=31.5508021390374, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI22758144, Length=187, Percent_Identity=31.5508021390374, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI150247226, Length=190, Percent_Identity=33.1578947368421, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI7705855, Length=195, Percent_Identity=28.7179487179487, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI157739938, Length=205, Percent_Identity=26.3414634146341, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI22507405, Length=185, Percent_Identity=29.1891891891892, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI7657478, Length=191, Percent_Identity=30.8900523560209, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI4557649, Length=191, Percent_Identity=28.2722513089005, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI19743808, Length=190, Percent_Identity=28.4210526315789, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI50726952, Length=188, Percent_Identity=32.9787234042553, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI5031737, Length=200, Percent_Identity=29, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI33667109, Length=201, Percent_Identity=29.3532338308458, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI119392083, Length=187, Percent_Identity=28.8770053475936, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4504503, Length=185, Percent_Identity=27.5675675675676, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI7705925, Length=186, Percent_Identity=27.9569892473118, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI226371731, Length=188, Percent_Identity=27.1276595744681, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI44680136, Length=224, Percent_Identity=24.1071428571429, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI44680133, Length=224, Percent_Identity=24.1071428571429, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI17738292, Length=224, Percent_Identity=24.1071428571429, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI66933014, Length=230, Percent_Identity=31.304347826087, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1787820, Length=246, Percent_Identity=53.2520325203252, Blast_Score=269, Evalue=2e-73,
Organism=Escherichia coli, GI1787335, Length=186, Percent_Identity=31.1827956989247, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786701, Length=202, Percent_Identity=30.1980198019802, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI87082100, Length=188, Percent_Identity=33.5106382978723, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1786812, Length=245, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082160, Length=196, Percent_Identity=30.1020408163265, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1790717, Length=193, Percent_Identity=26.9430051813472, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=242, Percent_Identity=34.297520661157, Blast_Score=110, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17562990, Length=242, Percent_Identity=33.8842975206612, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17560332, Length=243, Percent_Identity=30.8641975308642, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71994604, Length=230, Percent_Identity=29.5652173913043, Blast_Score=101, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71994600, Length=231, Percent_Identity=28.5714285714286, Blast_Score=100, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17562904, Length=201, Percent_Identity=32.8358208955224, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17562910, Length=193, Percent_Identity=31.0880829015544, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17562908, Length=193, Percent_Identity=32.6424870466321, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17563726, Length=242, Percent_Identity=31.404958677686, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17559104, Length=198, Percent_Identity=31.3131313131313, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17565030, Length=214, Percent_Identity=30.3738317757009, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI193204405, Length=194, Percent_Identity=33.5051546391753, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17560220, Length=195, Percent_Identity=34.3589743589744, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17562906, Length=198, Percent_Identity=29.7979797979798, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17538480, Length=239, Percent_Identity=29.7071129707113, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17538486, Length=199, Percent_Identity=29.6482412060301, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI72000259, Length=241, Percent_Identity=29.8755186721992, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17551412, Length=209, Percent_Identity=27.7511961722488, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17544670, Length=247, Percent_Identity=27.1255060728745, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17531453, Length=216, Percent_Identity=27.7777777777778, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17560676, Length=190, Percent_Identity=27.8947368421053, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17555706, Length=194, Percent_Identity=27.319587628866, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI25152911, Length=202, Percent_Identity=27.2277227722772, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115534694, Length=190, Percent_Identity=29.4736842105263, Blast_Score=64, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI115534660, Length=184, Percent_Identity=22.8260869565217, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=247, Percent_Identity=38.8663967611336, Blast_Score=168, Evalue=6e-43,
Organism=Saccharomyces cerevisiae, GI6322227, Length=232, Percent_Identity=27.5862068965517, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6322067, Length=230, Percent_Identity=26.0869565217391, Blast_Score=73, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6322226, Length=186, Percent_Identity=23.6559139784946, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI116007236, Length=251, Percent_Identity=32.2709163346614, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24641232, Length=256, Percent_Identity=30.078125, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI23397609, Length=233, Percent_Identity=31.3304721030043, Blast_Score=104, Evalue=4e-23,
Organism=Drosophila melanogaster, GI21357041, Length=198, Percent_Identity=35.8585858585859, Blast_Score=100, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24641388, Length=258, Percent_Identity=29.4573643410853, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI116007234, Length=255, Percent_Identity=30.9803921568627, Blast_Score=97, Evalue=9e-21,
Organism=Drosophila melanogaster, GI28571526, Length=187, Percent_Identity=33.1550802139037, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24644339, Length=191, Percent_Identity=33.5078534031414, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24648693, Length=256, Percent_Identity=29.296875, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI21355889, Length=256, Percent_Identity=29.296875, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24640442, Length=210, Percent_Identity=29.0476190476191, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24643142, Length=185, Percent_Identity=32.972972972973, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI21358495, Length=229, Percent_Identity=28.3842794759825, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI28571387, Length=256, Percent_Identity=27.734375, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI116007238, Length=185, Percent_Identity=31.8918918918919, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24648944, Length=236, Percent_Identity=26.6949152542373, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI281364494, Length=261, Percent_Identity=23.7547892720307, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24663911, Length=255, Percent_Identity=25.0980392156863, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28574402, Length=188, Percent_Identity=29.7872340425532, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24584744, Length=188, Percent_Identity=29.7872340425532, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24584748, Length=196, Percent_Identity=26.530612244898, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI161076933, Length=196, Percent_Identity=26.530612244898, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24584752, Length=185, Percent_Identity=28.1081081081081, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI116007232, Length=188, Percent_Identity=29.7872340425532, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.276 [H]

Molecular weight: Translated: 26400; Mature: 26269

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTVLITGATSGFGSAAVRRFAAAGWKVIATGRRAERLQALAAELPAGQVHTAAFDMRD
CCCEEEEEECCCCCHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHCCCCCEEHHHHHHHH
ARALSDAIDAVPAAFADIDVLVNNAGLALGTAPAQQADLAQWQQMIDTNVTALVTLTHRL
HHHHHHHHHHHHHHHHHHEEEEECCCEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHH
LPALIARRGAIINIASVAATYPYTGGNVYGGTKAFVQQFSLGLRSDLHGTGVRVTSIEPG
HHHHHHHCCCEEEEHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCC
MAETEFTLVRTGGNQAASDTLYRGATPMTAEDIAEQIFYVASLPAHLNINRLEIMPVTQS
CCCCEEEEEEECCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCC
FAGFQVARDAQ
CCCCEECCCCC
>Mature Secondary Structure 
SKTVLITGATSGFGSAAVRRFAAAGWKVIATGRRAERLQALAAELPAGQVHTAAFDMRD
CCEEEEEECCCCCHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHCCCCCEEHHHHHHHH
ARALSDAIDAVPAAFADIDVLVNNAGLALGTAPAQQADLAQWQQMIDTNVTALVTLTHRL
HHHHHHHHHHHHHHHHHHEEEEECCCEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHH
LPALIARRGAIINIASVAATYPYTGGNVYGGTKAFVQQFSLGLRSDLHGTGVRVTSIEPG
HHHHHHHCCCEEEEHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCC
MAETEFTLVRTGGNQAASDTLYRGATPMTAEDIAEQIFYVASLPAHLNINRLEIMPVTQS
CCCCEEEEEEECCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCC
FAGFQVARDAQ
CCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]