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The map label for this gene is argS [H]

Identifier: 21244635

GI number: 21244635

Start: 4601625

End: 4603334

Strand: Direct

Name: argS [H]

Synonym: XAC3916

Alternate gene names: 21244635

Gene position: 4601625-4603334 (Clockwise)

Preceding gene: 21244634

Following gene: 21244636

Centisome position: 88.91

GC content: 65.44

Gene sequence:

>1710_bases
TTGGTTCCAAGCAGATCCCACGTGAAAGCCCTACTCCGCGCACTGATCGGCCAAGGCATTGAAGCCTTGCGCGCCAATGG
CACCCTGCCCGCCGACACCCTGCCGCCGGATTTTGTGGTCGAGCGACCCAAGACCCGCGAGCACGGCGACTTCGCCACCA
ACGCCGCGATGCTGCTGGCCAAGGCTGCGCGCAGCAATCCGCGCGCACTGGCGCAGGCGCTGCTGGCGGCCCTGCCGGCC
AGCGACGACGTGGCCAAGGTGGAAATCGCCGGTCCGGGCTTCATCAATTTCCACCTGGCCCCCACCGCGTATCAGCGCGA
AGTGGCGCATGTGATCAAGCAAGGCCACGACTACGGACGCGGCCTGGCCGGCAACGGCCGTTCGGTGGGCGTGGAATACG
TCTCGGCCAACCCGACCGGCCCGCTGCATGTCGGCCACGGCCGTGCCGCGGCGATCGGCGACAGCCTGGCGCGCGTGCTC
GATGCCAACGGCTGGAACGTCAAGCGCGAGTTCTACTACAACGATGCCGGCGTGCAGATCGAGAACCTGGCGCTGTCGGT
ACAGGCACGTGCGCAGGGGCTCACCCCCGACAGCGACGGCTGGCCGGAAAACGGCTACCGCGGCGACTACATCGCCGATG
TGGCCAATGCCTACCTGGCCGGCGACACCGTCGATCTGGAAGGCCATCTGGTCACCGGCACCAAGGATCCGGCCGATCTC
GAATCGATCCGCCGCTTCGCGGTGGCGTACCTGCGTAACGAGCAGAACCACGACCTGGCTGCGTTCCGGGTCGATTTCGA
CATCTACTTCCTGGAAAGCTCGCTGTACAAGGACGGCAAGGTCGAAGAAGCGGTGCAGAAGCTGATCGCCTCCGGCCACA
CCTACGAGGAAGGCGGCGCGCTGTGGCTGAAGTCCACCGACTTCGGCGACGACAAGGACCGCGTCATGCGCAAGTCCGAC
GGCACCTACACCTATTTCGTGCCGGACGTGGCCTATCACCTGACCAAGTGGCAACGCGGCTACGAACGCGCCATCACCGA
ACTGGGCGCCGACCACCACGGCTCGCTGACGCGCGTGCGCGCCGGCCTGCAGGCGATGGAGCTGGGCATCCCGCAGGGTT
GGCCGGAATACGTGCTGCACCAGATGGTCACGGTGATGCGCGGCGGCGAAGAAGTGAAACTGTCCAAGCGTGCCGGCAGC
TACGTCACCCTGCGCGACCTCATCGAAGAAACCAGCGCCGATGCGGTGCGCTGGTTCCTGATCGCGCGCAAGCCCGATTC
GCAGCTGACCTTCGATATCGACCTGGCGCGGGCGCAGAGCAACGACAACCCGGTGTTCTACGTGCAGTACGCCCATGCGC
GGGTATGCAGCGTGCTGCGCCAGGCGCAGGAAAAGGGCTACAAGTACGACCAAGCCCATGGTCTGGCCGAGCTCGCATGC
CTGGACGACGAACACTCGCTGGCGGTGATGCTGGAGCTGTCGCGTTACCCGGAAGTGGTGGAAATCGCCGGTCAGGCGTT
GGAGCCGTACCAGATCGCGCAATACCTGCGTGAATTGGCGCACGCCTTCCACACGTGGTATCACAACAGCAAGGTGCTGG
TGGACGCTGCCGCCGAGCGCGACGCCAAGCTCACCCTGGCGGTCGCCACCCAACAGGTGCTGGCCAATGGCCTGGAACTG
CTCGGCGTCAGCGCTCCGGAAAAGATGTAA

Upstream 100 bases:

>100_bases
GGTGTCGTTCGCCGAACGCGGCTGGCTGGAATGAGCAGTGGTGCGCTGACCTGAACCATTGCTCGGACCCTGCGGCACGC
GGTCGGGTAAAATCGCTGGT

Downstream 100 bases:

>100_bases
ACAGGCGGTAGCTCCCGGGCGCCATCGCAGGCAGCAGCGTAGCGCATGGCACTGCGGTAGGCGCCGGCCTGCCACCTCGG
GCGCTGATGGCGCTCACCGG

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 569; Mature: 569

Protein sequence:

>569_residues
MVPSRSHVKALLRALIGQGIEALRANGTLPADTLPPDFVVERPKTREHGDFATNAAMLLAKAARSNPRALAQALLAALPA
SDDVAKVEIAGPGFINFHLAPTAYQREVAHVIKQGHDYGRGLAGNGRSVGVEYVSANPTGPLHVGHGRAAAIGDSLARVL
DANGWNVKREFYYNDAGVQIENLALSVQARAQGLTPDSDGWPENGYRGDYIADVANAYLAGDTVDLEGHLVTGTKDPADL
ESIRRFAVAYLRNEQNHDLAAFRVDFDIYFLESSLYKDGKVEEAVQKLIASGHTYEEGGALWLKSTDFGDDKDRVMRKSD
GTYTYFVPDVAYHLTKWQRGYERAITELGADHHGSLTRVRAGLQAMELGIPQGWPEYVLHQMVTVMRGGEEVKLSKRAGS
YVTLRDLIEETSADAVRWFLIARKPDSQLTFDIDLARAQSNDNPVFYVQYAHARVCSVLRQAQEKGYKYDQAHGLAELAC
LDDEHSLAVMLELSRYPEVVEIAGQALEPYQIAQYLRELAHAFHTWYHNSKVLVDAAAERDAKLTLAVATQQVLANGLEL
LGVSAPEKM

Sequences:

>Translated_569_residues
MVPSRSHVKALLRALIGQGIEALRANGTLPADTLPPDFVVERPKTREHGDFATNAAMLLAKAARSNPRALAQALLAALPA
SDDVAKVEIAGPGFINFHLAPTAYQREVAHVIKQGHDYGRGLAGNGRSVGVEYVSANPTGPLHVGHGRAAAIGDSLARVL
DANGWNVKREFYYNDAGVQIENLALSVQARAQGLTPDSDGWPENGYRGDYIADVANAYLAGDTVDLEGHLVTGTKDPADL
ESIRRFAVAYLRNEQNHDLAAFRVDFDIYFLESSLYKDGKVEEAVQKLIASGHTYEEGGALWLKSTDFGDDKDRVMRKSD
GTYTYFVPDVAYHLTKWQRGYERAITELGADHHGSLTRVRAGLQAMELGIPQGWPEYVLHQMVTVMRGGEEVKLSKRAGS
YVTLRDLIEETSADAVRWFLIARKPDSQLTFDIDLARAQSNDNPVFYVQYAHARVCSVLRQAQEKGYKYDQAHGLAELAC
LDDEHSLAVMLELSRYPEVVEIAGQALEPYQIAQYLRELAHAFHTWYHNSKVLVDAAAERDAKLTLAVATQQVLANGLEL
LGVSAPEKM
>Mature_569_residues
MVPSRSHVKALLRALIGQGIEALRANGTLPADTLPPDFVVERPKTREHGDFATNAAMLLAKAARSNPRALAQALLAALPA
SDDVAKVEIAGPGFINFHLAPTAYQREVAHVIKQGHDYGRGLAGNGRSVGVEYVSANPTGPLHVGHGRAAAIGDSLARVL
DANGWNVKREFYYNDAGVQIENLALSVQARAQGLTPDSDGWPENGYRGDYIADVANAYLAGDTVDLEGHLVTGTKDPADL
ESIRRFAVAYLRNEQNHDLAAFRVDFDIYFLESSLYKDGKVEEAVQKLIASGHTYEEGGALWLKSTDFGDDKDRVMRKSD
GTYTYFVPDVAYHLTKWQRGYERAITELGADHHGSLTRVRAGLQAMELGIPQGWPEYVLHQMVTVMRGGEEVKLSKRAGS
YVTLRDLIEETSADAVRWFLIARKPDSQLTFDIDLARAQSNDNPVFYVQYAHARVCSVLRQAQEKGYKYDQAHGLAELAC
LDDEHSLAVMLELSRYPEVVEIAGQALEPYQIAQYLRELAHAFHTWYHNSKVLVDAAAERDAKLTLAVATQQVLANGLEL
LGVSAPEKM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=635, Percent_Identity=23.9370078740157, Blast_Score=110, Evalue=5e-24,
Organism=Escherichia coli, GI1788184, Length=603, Percent_Identity=26.2023217247098, Blast_Score=126, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI71985061, Length=638, Percent_Identity=22.7272727272727, Blast_Score=103, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI71985068, Length=598, Percent_Identity=22.742474916388, Blast_Score=92, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6320548, Length=604, Percent_Identity=25, Blast_Score=127, Evalue=6e-30,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 62563; Mature: 62563

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPSRSHVKALLRALIGQGIEALRANGTLPADTLPPDFVVERPKTREHGDFATNAAMLLA
CCCCHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHH
KAARSNPRALAQALLAALPASDDVAKVEIAGPGFINFHLAPTAYQREVAHVIKQGHDYGR
HHHCCCHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEEECCHHHHHHHHHHHHCCCCCCC
GLAGNGRSVGVEYVSANPTGPLHVGHGRAAAIGDSLARVLDANGWNVKREFYYNDAGVQI
CCCCCCCEEEEEEEECCCCCCEEECCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEE
ENLALSVQARAQGLTPDSDGWPENGYRGDYIADVANAYLAGDTVDLEGHLVTGTKDPADL
EEEEEEEEHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEECCCEEEECCCCCHHH
ESIRRFAVAYLRNEQNHDLAAFRVDFDIYFLESSLYKDGKVEEAVQKLIASGHTYEEGGA
HHHHHHHHHHHHCCCCCCEEEEEEEEEEEEEEHHHCCCCCHHHHHHHHHHCCCCCCCCCE
LWLKSTDFGDDKDRVMRKSDGTYTYFVPDVAYHLTKWQRGYERAITELGADHHGSLTRVR
EEEECCCCCCCHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
AGLQAMELGIPQGWPEYVLHQMVTVMRGGEEVKLSKRAGSYVTLRDLIEETSADAVRWFL
HHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEHHHHHHHHCCCCEEEEEE
IARKPDSQLTFDIDLARAQSNDNPVFYVQYAHARVCSVLRQAQEKGYKYDQAHGLAELAC
EEECCCCCEEEEEEEEECCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCHHHCCCEEEEE
LDDEHSLAVMLELSRYPEVVEIAGQALEPYQIAQYLRELAHAFHTWYHNSKVLVDAAAER
ECCCCCEEEEEEEHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCC
DAKLTLAVATQQVLANGLELLGVSAPEKM
CCEEEEHHHHHHHHHCCHHEEECCCCCCC
>Mature Secondary Structure
MVPSRSHVKALLRALIGQGIEALRANGTLPADTLPPDFVVERPKTREHGDFATNAAMLLA
CCCCHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHH
KAARSNPRALAQALLAALPASDDVAKVEIAGPGFINFHLAPTAYQREVAHVIKQGHDYGR
HHHCCCHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEEECCHHHHHHHHHHHHCCCCCCC
GLAGNGRSVGVEYVSANPTGPLHVGHGRAAAIGDSLARVLDANGWNVKREFYYNDAGVQI
CCCCCCCEEEEEEEECCCCCCEEECCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEE
ENLALSVQARAQGLTPDSDGWPENGYRGDYIADVANAYLAGDTVDLEGHLVTGTKDPADL
EEEEEEEEHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEECCCEEEECCCCCHHH
ESIRRFAVAYLRNEQNHDLAAFRVDFDIYFLESSLYKDGKVEEAVQKLIASGHTYEEGGA
HHHHHHHHHHHHCCCCCCEEEEEEEEEEEEEEHHHCCCCCHHHHHHHHHHCCCCCCCCCE
LWLKSTDFGDDKDRVMRKSDGTYTYFVPDVAYHLTKWQRGYERAITELGADHHGSLTRVR
EEEECCCCCCCHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
AGLQAMELGIPQGWPEYVLHQMVTVMRGGEEVKLSKRAGSYVTLRDLIEETSADAVRWFL
HHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEHHHHHHHHCCCCEEEEEE
IARKPDSQLTFDIDLARAQSNDNPVFYVQYAHARVCSVLRQAQEKGYKYDQAHGLAELAC
EEECCCCCEEEEEEEEECCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCHHHCCCEEEEE
LDDEHSLAVMLELSRYPEVVEIAGQALEPYQIAQYLRELAHAFHTWYHNSKVLVDAAAER
ECCCCCEEEEEEEHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCC
DAKLTLAVATQQVLANGLELLGVSAPEKM
CCEEEEHHHHHHHHHCCHHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]