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The map label for this gene is gcp [H]

Identifier: 21244595

GI number: 21244595

Start: 4554865

End: 4555923

Strand: Reverse

Name: gcp [H]

Synonym: XAC3871

Alternate gene names: 21244595

Gene position: 4555923-4554865 (Counterclockwise)

Preceding gene: 21244603

Following gene: 21244594

Centisome position: 88.03

GC content: 69.97

Gene sequence:

>1059_bases
GTGAAAGTTCTTGGGATCGAATCATCGTGCGATGAGACCGGCGTAGCGGTCTACGACACCGAATTATCCGGCGTGCCGGC
GCTGCGCGCGCATGCGGTCTACAGCCAGATCGCGCTGCATGCCGAATACGGCGGCGTGGTACCGGAGCTTGCCAGCCGCG
ACCATGTGCGCAAGCTGCTGCCGCTGATCCGCCAGACCCTGGGCGAGGCCGGGCTGCGCATCGACGAACTGGATGGTGTG
GCCTACACCGCGGGGCCGGGGCTGGTCGGCGCATTGCTGGTCGGTGCCGGCGTGGCGCGCTCGCTGGCCTGGGCATTGGA
TGTGCCGGCGATCGGCGTGCACCATATGGAAGGCCACTTGCTGGCGCCGTTGATGGAAGACGACCCGCCGCAGGCGCCGT
TCGTGGCCTTGCTGGTATCCGGCGGGCATACCCAACTGGTGTCGGTGAAGGCGCTGGGCAGCTACCAAGTGCTGGGCGAG
ACGCTGGACGATGCGGCCGGCGAAGCCTTCGACAAGACCGCCAAGATGATGGGCCTGCCGTACCCGGGCGGCCCGCAGCT
GGCCGCCTTGGCCGAAACCGGCACGCCGGGGCGCTATAAGTTCGCGCGGCCGATGACCGACCGGCCCGGCCTGGATTTCA
GTTTCAGTGGGCTCAAGACCCAGGTGCTGCTGGCCTGGCGGTCCAGCGACCAGTCCGACACCACCCGGGCGGACATCGCG
CGCGGCTTCGAAGACGCGGTGGTGGACACCCTGGCCATCAAGTGCCTGCGCGCGCTGGACGCGGCCGGCTGCGACACCCT
GGTGGTGGCCGGCGGCGTGGGCGCAAACAAGCGCCTGCGCGCGCGCCTGCAAGAGGCTGCCCAGCGCCGCGGCGGCCGGG
TCTGCTTCCCGCGCCCGGCCTTGTGCACCGACAACGGCGCGATGATCGCCTTCGCCGGCGCGCTGCGGCTGCAGGCCGGT
GAGCATGCGGATGCGGCGGTGCATGTGACGCCGCGGTGGGATATGGCGGCGCTGCCGCCACTGGCGGCGCAGGAATCGGG
AGTGGGGAATCGGGAATAG

Upstream 100 bases:

>100_bases
ATGCGGCCGGCACGGTAGGGCGATGCAGCATCTTGCCATCGGCCGATCTGCGCAGCACAAAAGCTGCGAAAATAGCTGCA
TCTCCCCATGCCGAGCTGCC

Downstream 100 bases:

>100_bases
TGAAGAGTGAAGAGTGAAGAACTCTACTCCGATCCTATCCGTACGTGCGCTGTTGTCTTTGCTCCTACCAATTCCCTATT
CCCGACTCCCGATTCCCCAT

Product: DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MKVLGIESSCDETGVAVYDTELSGVPALRAHAVYSQIALHAEYGGVVPELASRDHVRKLLPLIRQTLGEAGLRIDELDGV
AYTAGPGLVGALLVGAGVARSLAWALDVPAIGVHHMEGHLLAPLMEDDPPQAPFVALLVSGGHTQLVSVKALGSYQVLGE
TLDDAAGEAFDKTAKMMGLPYPGGPQLAALAETGTPGRYKFARPMTDRPGLDFSFSGLKTQVLLAWRSSDQSDTTRADIA
RGFEDAVVDTLAIKCLRALDAAGCDTLVVAGGVGANKRLRARLQEAAQRRGGRVCFPRPALCTDNGAMIAFAGALRLQAG
EHADAAVHVTPRWDMAALPPLAAQESGVGNRE

Sequences:

>Translated_352_residues
MKVLGIESSCDETGVAVYDTELSGVPALRAHAVYSQIALHAEYGGVVPELASRDHVRKLLPLIRQTLGEAGLRIDELDGV
AYTAGPGLVGALLVGAGVARSLAWALDVPAIGVHHMEGHLLAPLMEDDPPQAPFVALLVSGGHTQLVSVKALGSYQVLGE
TLDDAAGEAFDKTAKMMGLPYPGGPQLAALAETGTPGRYKFARPMTDRPGLDFSFSGLKTQVLLAWRSSDQSDTTRADIA
RGFEDAVVDTLAIKCLRALDAAGCDTLVVAGGVGANKRLRARLQEAAQRRGGRVCFPRPALCTDNGAMIAFAGALRLQAG
EHADAAVHVTPRWDMAALPPLAAQESGVGNRE
>Mature_352_residues
MKVLGIESSCDETGVAVYDTELSGVPALRAHAVYSQIALHAEYGGVVPELASRDHVRKLLPLIRQTLGEAGLRIDELDGV
AYTAGPGLVGALLVGAGVARSLAWALDVPAIGVHHMEGHLLAPLMEDDPPQAPFVALLVSGGHTQLVSVKALGSYQVLGE
TLDDAAGEAFDKTAKMMGLPYPGGPQLAALAETGTPGRYKFARPMTDRPGLDFSFSGLKTQVLLAWRSSDQSDTTRADIA
RGFEDAVVDTLAIKCLRALDAAGCDTLVVAGGVGANKRLRARLQEAAQRRGGRVCFPRPALCTDNGAMIAFAGALRLQAG
EHADAAVHVTPRWDMAALPPLAAQESGVGNRE

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=341, Percent_Identity=32.5513196480938, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI8923380, Length=338, Percent_Identity=31.3609467455621, Blast_Score=127, Evalue=2e-29,
Organism=Escherichia coli, GI1789445, Length=339, Percent_Identity=66.3716814159292, Blast_Score=454, Evalue=1e-129,
Organism=Caenorhabditis elegans, GI17557464, Length=332, Percent_Identity=29.2168674698795, Blast_Score=135, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI71995670, Length=331, Percent_Identity=32.3262839879154, Blast_Score=129, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6320099, Length=342, Percent_Identity=32.7485380116959, Blast_Score=142, Evalue=6e-35,
Organism=Saccharomyces cerevisiae, GI6322891, Length=296, Percent_Identity=29.3918918918919, Blast_Score=114, Evalue=2e-26,
Organism=Drosophila melanogaster, GI20129063, Length=343, Percent_Identity=35.2769679300292, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI21357207, Length=333, Percent_Identity=31.2312312312312, Blast_Score=137, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 36841; Mature: 36841

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLGIESSCDETGVAVYDTELSGVPALRAHAVYSQIALHAEYGGVVPELASRDHVRKLL
CEEECCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHCHHHHHHHH
PLIRQTLGEAGLRIDELDGVAYTAGPGLVGALLVGAGVARSLAWALDVPAIGVHHMEGHL
HHHHHHHHHHCCEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCE
LAPLMEDDPPQAPFVALLVSGGHTQLVSVKALGSYQVLGETLDDAAGEAFDKTAKMMGLP
ECCCCCCCCCCCCEEEEEEECCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCC
YPGGPQLAALAETGTPGRYKFARPMTDRPGLDFSFSGLKTQVLLAWRSSDQSDTTRADIA
CCCCCCEEEEECCCCCCCEEECCCCCCCCCCCEEECCCCEEEEEEECCCCCCCHHHHHHH
RGFEDAVVDTLAIKCLRALDAAGCDTLVVAGGVGANKRLRARLQEAAQRRGGRVCFPRPA
HCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCEEECCCCC
LCTDNGAMIAFAGALRLQAGEHADAAVHVTPRWDMAALPPLAAQESGVGNRE
EECCCCCEEEEEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKVLGIESSCDETGVAVYDTELSGVPALRAHAVYSQIALHAEYGGVVPELASRDHVRKLL
CEEECCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHCHHHHHHHH
PLIRQTLGEAGLRIDELDGVAYTAGPGLVGALLVGAGVARSLAWALDVPAIGVHHMEGHL
HHHHHHHHHHCCEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCE
LAPLMEDDPPQAPFVALLVSGGHTQLVSVKALGSYQVLGETLDDAAGEAFDKTAKMMGLP
ECCCCCCCCCCCCEEEEEEECCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCC
YPGGPQLAALAETGTPGRYKFARPMTDRPGLDFSFSGLKTQVLLAWRSSDQSDTTRADIA
CCCCCCEEEEECCCCCCCEEECCCCCCCCCCCEEECCCCEEEEEEECCCCCCCHHHHHHH
RGFEDAVVDTLAIKCLRALDAAGCDTLVVAGGVGANKRLRARLQEAAQRRGGRVCFPRPA
HCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCEEECCCCC
LCTDNGAMIAFAGALRLQAGEHADAAVHVTPRWDMAALPPLAAQESGVGNRE
EECCCCCEEEEEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA