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The map label for this gene is rho [H]

Identifier: 21244555

GI number: 21244555

Start: 4505458

End: 4506738

Strand: Direct

Name: rho [H]

Synonym: XAC3831

Alternate gene names: 21244555

Gene position: 4505458-4506738 (Clockwise)

Preceding gene: 21244554

Following gene: 21244560

Centisome position: 87.05

GC content: 62.37

Gene sequence:

>1281_bases
GTGCCGGAAGGTTTTCCGGTGTATTCGCTGAGCGACCTCAAGCGGATGCCGGCGCAGAAGCTGCTGGATATCGCCGACCA
GCTCAATATTCAGGAAGGCGTGGCGCGTGCGCGCAAGCAGGACGTGATCTTCGCCCTGCTCAAGGTGCTGACCCGTCATG
GTGAAGGCGTTGCCGCCGACGGCGTGCTGGAAATCCTGCCCGACGGCTTCGGTTTCCTGCGTGCGGCAGAAGCCAGCTAC
CTGGCCGGCCCGGACGATACCTATATTTCGCCCAGCCAGATCCGCCGCTTCAACCTGCGTACCGGCGACCACCTCTCCGG
CCGCATCCGCTTCCCGAAGGACGGCGAACGCTATTTCGCGCTGTCGATCGTCGACACCATCAATGGCGAGCCGCTGGAAG
CGAGCAAGAACAAGGTCCTGTTCGAGAACCTGACCCCGCTGTTCCCGCGCCGCCGCTTCCGTCTGGAGCGTGGCGATGGC
TCCACCGAGGACATCACCGGCCGCATCCTGGATCTGATGGCACCGCAGGGCAAGGGTCAGCGTGCGCTGATCGTCTCCCC
GCCCAAGGCCGGTAAGACGATGATGATGCAGCAGGTGGCCACGGCCATCACCACCAATCATCCCGAAGTGCACATGATCG
TGCTGCTCATCGACGAGCGCCCGGAAGAAGTGACCGAAATGCAGCGCACCGTGCGCGGCGAAGTCATCTCCTCCACGTTC
GACGAGCCGGCTGCGCGTCACGTGCAGGTCGCCGAGATGGTGATCGAGCGGGCCAAGCGCCTGGTCGAGCACAAGAAGGA
CGTGGTGATCCTGCTGGACTCCATCACCCGCCTGGCGCGCGCCTACAACAACGTAGTGCCCAGCTCCGGCAAGGTGCTCA
CCGGCGGTGTGGATGCCAATGCGTTGCACCGCCCGAAGCGCTTCTTCGGCGCGGCGCGTAACGTGGAAGAAGGCGGCTCG
CTGACCATCATCGCCACGGCGCTGGTGGAAACCGGCAGCAAGATGGACGAGGTGATCTACGAAGAGTTCAAGGGCACCGG
CAACAGCGAAGTGCATCTGAACCGTCGCATCACCGAAAAGCGCGTGTACCCGGCAATCGACATCAACCGTTCGGGCACGC
GTCGCGAAGATCTGCTGATCGAGCCGGAGTTGCTGCAGAAGATCTGGATCCTGCGCAAGCTGCTGCACCCGATGGACGAA
ATCGCAGCAATGGAATTCCTGTTGGACAAGATGAAGACCACCAAGTCCAACGACGAGTTCTTCAGTTCGATGAAGCGCTG
A

Upstream 100 bases:

>100_bases
CCGCCGCGATCGCGGCCCGCGCGACCGCTTCGGCAACGACGGCGGCATGCCCTCGTCCGACGGCAGCAACGAACCGTTCA
TCGCGCGTCCGCATCCGGCC

Downstream 100 bases:

>100_bases
GTTCAATCGGTTTATCGAGACGAAAAAGCCCCGCATTGCGGGGCTTTTTGTATGAGGCGACTGTCGCGCAGCCTTTAGTG
TCCTCCGTCAGCCGCTCTCA

Product: transcription termination factor Rho

Products: NA

Alternate protein names: ATP-dependent helicase Rho [H]

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MPEGFPVYSLSDLKRMPAQKLLDIADQLNIQEGVARARKQDVIFALLKVLTRHGEGVAADGVLEILPDGFGFLRAAEASY
LAGPDDTYISPSQIRRFNLRTGDHLSGRIRFPKDGERYFALSIVDTINGEPLEASKNKVLFENLTPLFPRRRFRLERGDG
STEDITGRILDLMAPQGKGQRALIVSPPKAGKTMMMQQVATAITTNHPEVHMIVLLIDERPEEVTEMQRTVRGEVISSTF
DEPAARHVQVAEMVIERAKRLVEHKKDVVILLDSITRLARAYNNVVPSSGKVLTGGVDANALHRPKRFFGAARNVEEGGS
LTIIATALVETGSKMDEVIYEEFKGTGNSEVHLNRRITEKRVYPAIDINRSGTRREDLLIEPELLQKIWILRKLLHPMDE
IAAMEFLLDKMKTTKSNDEFFSSMKR

Sequences:

>Translated_426_residues
MPEGFPVYSLSDLKRMPAQKLLDIADQLNIQEGVARARKQDVIFALLKVLTRHGEGVAADGVLEILPDGFGFLRAAEASY
LAGPDDTYISPSQIRRFNLRTGDHLSGRIRFPKDGERYFALSIVDTINGEPLEASKNKVLFENLTPLFPRRRFRLERGDG
STEDITGRILDLMAPQGKGQRALIVSPPKAGKTMMMQQVATAITTNHPEVHMIVLLIDERPEEVTEMQRTVRGEVISSTF
DEPAARHVQVAEMVIERAKRLVEHKKDVVILLDSITRLARAYNNVVPSSGKVLTGGVDANALHRPKRFFGAARNVEEGGS
LTIIATALVETGSKMDEVIYEEFKGTGNSEVHLNRRITEKRVYPAIDINRSGTRREDLLIEPELLQKIWILRKLLHPMDE
IAAMEFLLDKMKTTKSNDEFFSSMKR
>Mature_425_residues
PEGFPVYSLSDLKRMPAQKLLDIADQLNIQEGVARARKQDVIFALLKVLTRHGEGVAADGVLEILPDGFGFLRAAEASYL
AGPDDTYISPSQIRRFNLRTGDHLSGRIRFPKDGERYFALSIVDTINGEPLEASKNKVLFENLTPLFPRRRFRLERGDGS
TEDITGRILDLMAPQGKGQRALIVSPPKAGKTMMMQQVATAITTNHPEVHMIVLLIDERPEEVTEMQRTVRGEVISSTFD
EPAARHVQVAEMVIERAKRLVEHKKDVVILLDSITRLARAYNNVVPSSGKVLTGGVDANALHRPKRFFGAARNVEEGGSL
TIIATALVETGSKMDEVIYEEFKGTGNSEVHLNRRITEKRVYPAIDINRSGTRREDLLIEPELLQKIWILRKLLHPMDEI
AAMEFLLDKMKTTKSNDEFFSSMKR

Specific function: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template [H]

COG id: COG1158

COG function: function code K; Transcription termination factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Rho family [H]

Homologues:

Organism=Escherichia coli, GI1790217, Length=418, Percent_Identity=70.5741626794258, Blast_Score=622, Evalue=1e-179,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR011112
- InterPro:   IPR011113
- InterPro:   IPR004665 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF07498 Rho_N; PF07497 Rho_RNA_bind [H]

EC number: NA

Molecular weight: Translated: 47810; Mature: 47679

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEGFPVYSLSDLKRMPAQKLLDIADQLNIQEGVARARKQDVIFALLKVLTRHGEGVAAD
CCCCCCCCCHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GVLEILPDGFGFLRAAEASYLAGPDDTYISPSQIRRFNLRTGDHLSGRIRFPKDGERYFA
CHHHHCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHEECCCCCCCCCCEEECCCCCCEEEE
LSIVDTINGEPLEASKNKVLFENLTPLFPRRRFRLERGDGSTEDITGRILDLMAPQGKGQ
EEEEECCCCCCCCCCCCEEEHHHCCCCCCHHHHEEECCCCCCHHHHHHHHHHHCCCCCCC
RALIVSPPKAGKTMMMQQVATAITTNHPEVHMIVLLIDERPEEVTEMQRTVRGEVISSTF
EEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHC
DEPAARHVQVAEMVIERAKRLVEHKKDVVILLDSITRLARAYNNVVPSSGKVLTGGVDAN
CCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCCCCCCEEECCCCCH
ALHRPKRFFGAARNVEEGGSLTIIATALVETGSKMDEVIYEEFKGTGNSEVHLNRRITEK
HHHCCHHHHHHHCCCCCCCCEEEEEHHHHHCCCHHHHHHHHHHCCCCCCEEEEECHHHHH
RVYPAIDINRSGTRREDLLIEPELLQKIWILRKLLHPMDEIAAMEFLLDKMKTTKSNDEF
HCCCEEECCCCCCCCHHCEECHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHH
FSSMKR
HHHHCC
>Mature Secondary Structure 
PEGFPVYSLSDLKRMPAQKLLDIADQLNIQEGVARARKQDVIFALLKVLTRHGEGVAAD
CCCCCCCCHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GVLEILPDGFGFLRAAEASYLAGPDDTYISPSQIRRFNLRTGDHLSGRIRFPKDGERYFA
CHHHHCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHEECCCCCCCCCCEEECCCCCCEEEE
LSIVDTINGEPLEASKNKVLFENLTPLFPRRRFRLERGDGSTEDITGRILDLMAPQGKGQ
EEEEECCCCCCCCCCCCEEEHHHCCCCCCHHHHEEECCCCCCHHHHHHHHHHHCCCCCCC
RALIVSPPKAGKTMMMQQVATAITTNHPEVHMIVLLIDERPEEVTEMQRTVRGEVISSTF
EEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHC
DEPAARHVQVAEMVIERAKRLVEHKKDVVILLDSITRLARAYNNVVPSSGKVLTGGVDAN
CCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCCCCCCEEECCCCCH
ALHRPKRFFGAARNVEEGGSLTIIATALVETGSKMDEVIYEEFKGTGNSEVHLNRRITEK
HHHCCHHHHHHHCCCCCCCCEEEEEHHHHHCCCHHHHHHHHHHCCCCCCEEEEECHHHHH
RVYPAIDINRSGTRREDLLIEPELLQKIWILRKLLHPMDEIAAMEFLLDKMKTTKSNDEF
HCCCEEECCCCCCCCHHCEECHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHH
FSSMKR
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]