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The map label for this gene is etfA [H]

Identifier: 21244312

GI number: 21244312

Start: 4253203

End: 4254147

Strand: Direct

Name: etfA [H]

Synonym: XAC3587

Alternate gene names: 21244312

Gene position: 4253203-4254147 (Clockwise)

Preceding gene: 21244311

Following gene: 21244313

Centisome position: 82.18

GC content: 66.14

Gene sequence:

>945_bases
ATGGCCAAGGTTCTCGTTGTTGCCGAACATCTCGACGGTCAGCTCAATGCGGCCACCGCCAAGACGCTGAGCGCTGCGCT
GGCGATCTCGGCCGAATCCATCGATGTGGTTGTGCTGGCAGCGGACCCGGCAGCGGTTGCAGCGCAGGCCGCGCAATTGG
CCGGCGTTGCCCGAGTGCTGACGGTGGCGAACCCCGCAAACGAACATGCCATCGCGCAGGTGCTGGGGCCGCAGATCGCC
CAGCTTGCCGGCCAGGGCTATACGCATGTCTTCGGCCCCTCCACCACCTTCGGCAAGGACCTGATGCCGGTCGTGGCTGC
GCTGCTGGGCGTCAACCAGATCTCCGATCTGATGTCGGTCGAAGACGCTTACACTTTCAAGCGTCCGATCTACGCAGGCA
ACGCCATCATCACCGTCAAGGCGCCGGCCGACCAGATCGTGGTCGCGACGGTGCGCAGCGCCTCGTGGCCGGAAGCGGCG
GCCGGCGGAAGCGCCGCTGTCGAGTCCGTGACCGTCGATGCGACGCTGCCGACCCATACCCGCTTCATCGGGCTGGCCGC
AGGCACCTCTGATCGCCCCGACTTGCAGAGCGCCAAACGCGTGGTCTCCGGTGGTCGCGGCGTCGGCTCGGCCGAGAACT
TCCAGCACATCTACAGCCTGGCCGACAAACTCGGTGCCGCCGTGGGCGCCTCGCGCGCGGCAGTGGATGCCGGTTACGTG
CCCAACGAGCTGCAGGTCGGCCAGACCGGCAAGATCATCGCCCCGGAGCTTTACGTGGCCATCGGCATCAGCGGCGCCAT
CCAGCATCTGACCGGCATCAAGGACGCCGGCACGATTGTGGCGATCAACAAGGACCCGGAGTCGCCGATCTTCGAGATTG
CCGATATCGGGCTGGTGGGGGATTTGTTTGCGCTGCTGCCGGAGTTGGAGGCTGCGTTGGGCTGA

Upstream 100 bases:

>100_bases
CCACCACCCACTACGCCGCGCCGTCCAAGCGCAGCCGCGGCGTGATGGTCAAGGACGCCGCCGAGCTGGTGGCCGCACTC
AAGCAGAAGGGGTTGCTGTA

Downstream 100 bases:

>100_bases
GGCCCTTCTGCTGCAATGGATTCGCCTTCGTCTTCTCGGATTGACGGTGCCGCAACATCGCGGCACCGTCTGGATTATCT
GGTCGGCTTCGTTGTGCTGC

Product: electron transfer flavoprotein alpha subunit

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MAKVLVVAEHLDGQLNAATAKTLSAALAISAESIDVVVLAADPAAVAAQAAQLAGVARVLTVANPANEHAIAQVLGPQIA
QLAGQGYTHVFGPSTTFGKDLMPVVAALLGVNQISDLMSVEDAYTFKRPIYAGNAIITVKAPADQIVVATVRSASWPEAA
AGGSAAVESVTVDATLPTHTRFIGLAAGTSDRPDLQSAKRVVSGGRGVGSAENFQHIYSLADKLGAAVGASRAAVDAGYV
PNELQVGQTGKIIAPELYVAIGISGAIQHLTGIKDAGTIVAINKDPESPIFEIADIGLVGDLFALLPELEAALG

Sequences:

>Translated_314_residues
MAKVLVVAEHLDGQLNAATAKTLSAALAISAESIDVVVLAADPAAVAAQAAQLAGVARVLTVANPANEHAIAQVLGPQIA
QLAGQGYTHVFGPSTTFGKDLMPVVAALLGVNQISDLMSVEDAYTFKRPIYAGNAIITVKAPADQIVVATVRSASWPEAA
AGGSAAVESVTVDATLPTHTRFIGLAAGTSDRPDLQSAKRVVSGGRGVGSAENFQHIYSLADKLGAAVGASRAAVDAGYV
PNELQVGQTGKIIAPELYVAIGISGAIQHLTGIKDAGTIVAINKDPESPIFEIADIGLVGDLFALLPELEAALG
>Mature_313_residues
AKVLVVAEHLDGQLNAATAKTLSAALAISAESIDVVVLAADPAAVAAQAAQLAGVARVLTVANPANEHAIAQVLGPQIAQ
LAGQGYTHVFGPSTTFGKDLMPVVAALLGVNQISDLMSVEDAYTFKRPIYAGNAIITVKAPADQIVVATVRSASWPEAAA
GGSAAVESVTVDATLPTHTRFIGLAAGTSDRPDLQSAKRVVSGGRGVGSAENFQHIYSLADKLGAAVGASRAAVDAGYVP
NELQVGQTGKIIAPELYVAIGISGAIQHLTGIKDAGTIVAINKDPESPIFEIADIGLVGDLFALLPELEAALG

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=312, Percent_Identity=48.7179487179487, Blast_Score=270, Evalue=9e-73,
Organism=Homo sapiens, GI189181759, Length=272, Percent_Identity=51.8382352941177, Blast_Score=259, Evalue=3e-69,
Organism=Escherichia coli, GI1786226, Length=281, Percent_Identity=36.6548042704626, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1787990, Length=121, Percent_Identity=42.9752066115703, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI87082157, Length=251, Percent_Identity=31.8725099601594, Blast_Score=89, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17506929, Length=312, Percent_Identity=50.9615384615385, Blast_Score=277, Evalue=5e-75,
Organism=Saccharomyces cerevisiae, GI6325261, Length=251, Percent_Identity=42.6294820717131, Blast_Score=208, Evalue=1e-54,
Organism=Drosophila melanogaster, GI17136898, Length=315, Percent_Identity=52.0634920634921, Blast_Score=284, Evalue=6e-77,
Organism=Drosophila melanogaster, GI24652801, Length=315, Percent_Identity=52.0634920634921, Blast_Score=284, Evalue=6e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31780; Mature: 31648

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKVLVVAEHLDGQLNAATAKTLSAALAISAESIDVVVLAADPAAVAAQAAQLAGVARVL
CCEEEEEEECCCCCCCHHHHHHHHHHHEEEECCEEEEEEECCCHHHHHHHHHHHHHHHHH
TVANPANEHAIAQVLGPQIAQLAGQGYTHVFGPSTTFGKDLMPVVAALLGVNQISDLMSV
HCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
EDAYTFKRPIYAGNAIITVKAPADQIVVATVRSASWPEAAAGGSAAVESVTVDATLPTHT
HHHHHHCCCEEECCEEEEEECCCCCEEEEEECCCCCCCCCCCCCHHHEEEEEEEECCCCE
RFIGLAAGTSDRPDLQSAKRVVSGGRGVGSAENFQHIYSLADKLGAAVGASRAAVDAGYV
EEEEEECCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCC
PNELQVGQTGKIIAPELYVAIGISGAIQHLTGIKDAGTIVAINKDPESPIFEIADIGLVG
CCCEEECCCCCEECCCEEEEEECHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHCCHHH
DLFALLPELEAALG
HHHHHHHHHHHHCC
>Mature Secondary Structure 
AKVLVVAEHLDGQLNAATAKTLSAALAISAESIDVVVLAADPAAVAAQAAQLAGVARVL
CEEEEEEECCCCCCCHHHHHHHHHHHEEEECCEEEEEEECCCHHHHHHHHHHHHHHHHH
TVANPANEHAIAQVLGPQIAQLAGQGYTHVFGPSTTFGKDLMPVVAALLGVNQISDLMSV
HCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
EDAYTFKRPIYAGNAIITVKAPADQIVVATVRSASWPEAAAGGSAAVESVTVDATLPTHT
HHHHHHCCCEEECCEEEEEECCCCCEEEEEECCCCCCCCCCCCCHHHEEEEEEEECCCCE
RFIGLAAGTSDRPDLQSAKRVVSGGRGVGSAENFQHIYSLADKLGAAVGASRAAVDAGYV
EEEEEECCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCC
PNELQVGQTGKIIAPELYVAIGISGAIQHLTGIKDAGTIVAINKDPESPIFEIADIGLVG
CCCEEECCCCCEECCCEEEEEECHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHCCHHH
DLFALLPELEAALG
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]