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The map label for this gene is etfB [H]

Identifier: 21244311

GI number: 21244311

Start: 4252457

End: 4253203

Strand: Direct

Name: etfB [H]

Synonym: XAC3586

Alternate gene names: 21244311

Gene position: 4252457-4253203 (Clockwise)

Preceding gene: 21244305

Following gene: 21244312

Centisome position: 82.16

GC content: 65.46

Gene sequence:

>747_bases
ATGAAAATCCTCGTCGCCTACAAGCGCGTGGTGGACTACAACGTCCGCATTCAGGTCAAGCCGGATGGCTCCGGCGTGGT
GACCGAGGGCGTCAAGCTCTCGCCCAACCCGTTCGACGAAATCGCCCTGGAAGAAGCATTGCGCCTGCGCGATGCCGGCA
TCGCCACGGAAGTCGTGGTCGCCACCCTGGCGCCGGCCGATGCGGCTGCGCACTTGCGCAACGGCCTGGCCATGGGCGCC
AATCGCGCAATCCATGTGGTGACCGATGCGGCTGTTCAGCCCCTGACCGCCGCACGCGCGCTGCTCAAATTGGTCGAGAA
GGAACAGCCGGATCTGGTCATCCTCGGCAAGCAGGCGATCGACGACGACGCCAATCAGACCGGCCAGATGCTCGCCACAC
TCTGGGGCCGCCCGCAGGCCACCTTCGCCGGCAAGCTCGTCGTTGCCGATGGCAAAGCCACGGTCACGCGCGAGGTCGAC
GCCGGCCTGGAGACGCTGGAAGTGGACCTGCCGGCGGTGATCACCACCGATCTGCGCCTGAACGAGCCGCGCTTCATCAA
GCTGCCGGACATCATGAAGGCCAAGAGCAAGCCATTGGAAACGCTGGCGTTTGCCGACCTGGGTATCGACGCGCATGACA
GCCTGACCACCACCCACTACGCCGCGCCGTCCAAGCGCAGCCGCGGCGTGATGGTCAAGGACGCCGCCGAGCTGGTGGCC
GCACTCAAGCAGAAGGGGTTGCTGTAA

Upstream 100 bases:

>100_bases
CGCCATCGCATGGTTCGCTTCACCCGGTTAGAATGACTCCACTCCCGTGCCTGCCGCCGCGGCCGGGCCTTCCCGCAATC
GCTGAAGGATCTCGTACACG

Downstream 100 bases:

>100_bases
TGGCCAAGGTTCTCGTTGTTGCCGAACATCTCGACGGTCAGCTCAATGCGGCCACCGCCAAGACGCTGAGCGCTGCGCTG
GCGATCTCGGCCGAATCCAT

Product: electron transfer flavoprotein beta subunit

Products: NA

Alternate protein names: Beta-ETF; Electron transfer flavoprotein small subunit; ETFSS [H]

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MKILVAYKRVVDYNVRIQVKPDGSGVVTEGVKLSPNPFDEIALEEALRLRDAGIATEVVVATLAPADAAAHLRNGLAMGA
NRAIHVVTDAAVQPLTAARALLKLVEKEQPDLVILGKQAIDDDANQTGQMLATLWGRPQATFAGKLVVADGKATVTREVD
AGLETLEVDLPAVITTDLRLNEPRFIKLPDIMKAKSKPLETLAFADLGIDAHDSLTTTHYAAPSKRSRGVMVKDAAELVA
ALKQKGLL

Sequences:

>Translated_248_residues
MKILVAYKRVVDYNVRIQVKPDGSGVVTEGVKLSPNPFDEIALEEALRLRDAGIATEVVVATLAPADAAAHLRNGLAMGA
NRAIHVVTDAAVQPLTAARALLKLVEKEQPDLVILGKQAIDDDANQTGQMLATLWGRPQATFAGKLVVADGKATVTREVD
AGLETLEVDLPAVITTDLRLNEPRFIKLPDIMKAKSKPLETLAFADLGIDAHDSLTTTHYAAPSKRSRGVMVKDAAELVA
ALKQKGLL
>Mature_248_residues
MKILVAYKRVVDYNVRIQVKPDGSGVVTEGVKLSPNPFDEIALEEALRLRDAGIATEVVVATLAPADAAAHLRNGLAMGA
NRAIHVVTDAAVQPLTAARALLKLVEKEQPDLVILGKQAIDDDANQTGQMLATLWGRPQATFAGKLVVADGKATVTREVD
AGLETLEVDLPAVITTDLRLNEPRFIKLPDIMKAKSKPLETLAFADLGIDAHDSLTTTHYAAPSKRSRGVMVKDAAELVA
ALKQKGLL

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2086

COG function: function code C; Electron transfer flavoprotein, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF beta-subunit/fixA family [H]

Homologues:

Organism=Homo sapiens, GI4503609, Length=250, Percent_Identity=52, Blast_Score=248, Evalue=3e-66,
Organism=Homo sapiens, GI62420877, Length=235, Percent_Identity=51.4893617021277, Blast_Score=227, Evalue=9e-60,
Organism=Escherichia coli, GI87081682, Length=256, Percent_Identity=29.6875, Blast_Score=68, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI25141345, Length=253, Percent_Identity=52.5691699604743, Blast_Score=236, Evalue=7e-63,
Organism=Saccharomyces cerevisiae, GI6321646, Length=253, Percent_Identity=43.0830039525692, Blast_Score=188, Evalue=6e-49,
Organism=Drosophila melanogaster, GI24651147, Length=249, Percent_Identity=49.3975903614458, Blast_Score=223, Evalue=1e-58,
Organism=Drosophila melanogaster, GI24651145, Length=249, Percent_Identity=49.3975903614458, Blast_Score=223, Evalue=1e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000049
- InterPro:   IPR014730
- InterPro:   IPR012255
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF [H]

EC number: NA

Molecular weight: Translated: 26466; Mature: 26466

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILVAYKRVVDYNVRIQVKPDGSGVVTEGVKLSPNPFDEIALEEALRLRDAGIATEVVV
CEEEEEEHHHHCCEEEEEEECCCCCEEECCEEECCCCHHHHHHHHHHHHHCCCCHHHHHH
ATLAPADAAAHLRNGLAMGANRAIHVVTDAAVQPLTAARALLKLVEKEQPDLVILGKQAI
HHCCCCHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCEEEEECHHC
DDDANQTGQMLATLWGRPQATFAGKLVVADGKATVTREVDAGLETLEVDLPAVITTDLRL
CCCCCHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEEEHHCCCEEEEECCCEEEEECEEE
NEPRFIKLPDIMKAKSKPLETLAFADLGIDAHDSLTTTHYAAPSKRSRGVMVKDAAELVA
CCCCEEECCHHHHHCCCCHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCEEEHHHHHHHH
ALKQKGLL
HHHHCCCC
>Mature Secondary Structure
MKILVAYKRVVDYNVRIQVKPDGSGVVTEGVKLSPNPFDEIALEEALRLRDAGIATEVVV
CEEEEEEHHHHCCEEEEEEECCCCCEEECCEEECCCCHHHHHHHHHHHHHCCCCHHHHHH
ATLAPADAAAHLRNGLAMGANRAIHVVTDAAVQPLTAARALLKLVEKEQPDLVILGKQAI
HHCCCCHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCEEEEECHHC
DDDANQTGQMLATLWGRPQATFAGKLVVADGKATVTREVDAGLETLEVDLPAVITTDLRL
CCCCCHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEEEHHCCCEEEEECCCEEEEECEEE
NEPRFIKLPDIMKAKSKPLETLAFADLGIDAHDSLTTTHYAAPSKRSRGVMVKDAAELVA
CCCCEEECCHHHHHCCCCHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCEEEHHHHHHHH
ALKQKGLL
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8599534; 12597275 [H]