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The map label for this gene is zraS [C]

Identifier: 21243999

GI number: 21243999

Start: 3854671

End: 3855936

Strand: Reverse

Name: zraS [C]

Synonym: XAC3273

Alternate gene names: 21243999

Gene position: 3855936-3854671 (Counterclockwise)

Preceding gene: 21244001

Following gene: 21243997

Centisome position: 74.5

GC content: 59.95

Gene sequence:

>1266_bases
ATGAAAAATACTCTGATGTCGCAAGATCGCTACCGCCAGATGGTGGAGCTGTCTCCTGACTCCATCAAAGAAGTTGCGCT
CGATGGCACGGTGAGGTTTGTCAATTCTCACGGCCTCGCCCGCATTGCCTCAGAGAACGCCGAACGTGTTGTCGGTCATC
CGTGGTCGTCGTTGTGGCCAGAAGAGGTCCGGGACAACGTGCATGATGCGATCGCGGCCGCTGCGAGAGGCGAGTGCCGA
CAGTTCGATGCCGAATGCACTACTCCGAGCGGTGAGCGGCGCTTTTGGCTCGTCTCAACTAGCCCACTCAAGAATGCGCT
GGGCGAAGTGGATGCTGTGCTAGCCATCAATCGCGATGTGACTGAGCGGCATCATGCCGAAGTCGCGTTACGCACCCTCA
ACGACAGCTTGCGTAGTCAGGCTGGGCCGGTCAGCGCGCAAACCCACCTGTCCCATGTCGTCGACGCCCGTATGGGCGAT
TCGCACCAGCGCGCTCGCGATCTTGAGGGTGAGCTCAGTATCGCTCTCGCAGCGCAGCGCATGGCGGAGGCGGTGGCCCA
GCAGGCCCAGAAGGGAGATGCAGTTGGCCAACTTCTTGCCGGCATGGTGCACGACTTCAACAATGTGCTTCAGGTCGCTT
CGGGTGCCGTGGAAATGGTGTTGTCGCGAGGGGATATGGACGACAAGAACCGTGTCCTGCTCGGCATGGCTGAGAGTGCC
CTGCAGCAAGGTGCGGCTATGTCAAAGCGCTTGCTTGGCTTTGCTCGCCATCATCCCTATTCGCCCGAGAGCACCGATGT
CGGCCGAATTGTGCAAGAAATGATGCCGCTCTTGAGCCAAGCGGTGGGATCAGGAATTGTCCTCGATTTGCACATAGAGC
CCAACCTCCCCATGGCCCTAGTGGATCCCCACAGTCTCCAGCGCGCCGTTATGAACCTGGTTGTCAATGCCCGTGATGCG
TGCGGCGCCGCTGGCACGATCACCATCGCTGCCGGGAGCCGCTTGGTGCAGGAAGTGCCGGAGGGCGCGGCGCACGCGCT
TGGGCAGTATGTGGTGCTCAGTGTGCGCGATACGGGGCAGGGCATCGAGCCGGAAGCACGCGATCGCATATTCGAGGCTT
ACTTCACTACCAAGGGACTAGGGAAAGGCACTGGCCTTGGCCTTGCGCAGGTTTACGGCACGATCAGGCGCGCAAACGGA
TTTGTCGATGTGCAATCAACACCAGGTCAAGGTGCCTGTTTTACCCTTGGCATGCCTTGCCCTTGA

Upstream 100 bases:

>100_bases
CAGGAGGAGCGATCATGGAGTCTCAACGGTGTGGGGTTCTGAGCGAGACCTTGGTCCATACTGTGCGAACTATGCGTGAT
TAAATGCCCCCTCTTACTGA

Downstream 100 bases:

>100_bases
TCATCGAGTCATGTGGCTGACCTCTAAGGAGCACTTGGCGCTCCCGCGCGGCCTCCAGATCCTTTAGCCGCTTAGCGTAA
GGCACGCTCATGCCGCCAAA

Product: histidine kinase-response regulator hybrid protein

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MKNTLMSQDRYRQMVELSPDSIKEVALDGTVRFVNSHGLARIASENAERVVGHPWSSLWPEEVRDNVHDAIAAAARGECR
QFDAECTTPSGERRFWLVSTSPLKNALGEVDAVLAINRDVTERHHAEVALRTLNDSLRSQAGPVSAQTHLSHVVDARMGD
SHQRARDLEGELSIALAAQRMAEAVAQQAQKGDAVGQLLAGMVHDFNNVLQVASGAVEMVLSRGDMDDKNRVLLGMAESA
LQQGAAMSKRLLGFARHHPYSPESTDVGRIVQEMMPLLSQAVGSGIVLDLHIEPNLPMALVDPHSLQRAVMNLVVNARDA
CGAAGTITIAAGSRLVQEVPEGAAHALGQYVVLSVRDTGQGIEPEARDRIFEAYFTTKGLGKGTGLGLAQVYGTIRRANG
FVDVQSTPGQGACFTLGMPCP

Sequences:

>Translated_421_residues
MKNTLMSQDRYRQMVELSPDSIKEVALDGTVRFVNSHGLARIASENAERVVGHPWSSLWPEEVRDNVHDAIAAAARGECR
QFDAECTTPSGERRFWLVSTSPLKNALGEVDAVLAINRDVTERHHAEVALRTLNDSLRSQAGPVSAQTHLSHVVDARMGD
SHQRARDLEGELSIALAAQRMAEAVAQQAQKGDAVGQLLAGMVHDFNNVLQVASGAVEMVLSRGDMDDKNRVLLGMAESA
LQQGAAMSKRLLGFARHHPYSPESTDVGRIVQEMMPLLSQAVGSGIVLDLHIEPNLPMALVDPHSLQRAVMNLVVNARDA
CGAAGTITIAAGSRLVQEVPEGAAHALGQYVVLSVRDTGQGIEPEARDRIFEAYFTTKGLGKGTGLGLAQVYGTIRRANG
FVDVQSTPGQGACFTLGMPCP
>Mature_421_residues
MKNTLMSQDRYRQMVELSPDSIKEVALDGTVRFVNSHGLARIASENAERVVGHPWSSLWPEEVRDNVHDAIAAAARGECR
QFDAECTTPSGERRFWLVSTSPLKNALGEVDAVLAINRDVTERHHAEVALRTLNDSLRSQAGPVSAQTHLSHVVDARMGD
SHQRARDLEGELSIALAAQRMAEAVAQQAQKGDAVGQLLAGMVHDFNNVLQVASGAVEMVLSRGDMDDKNRVLLGMAESA
LQQGAAMSKRLLGFARHHPYSPESTDVGRIVQEMMPLLSQAVGSGIVLDLHIEPNLPMALVDPHSLQRAVMNLVVNARDA
CGAAGTITIAAGSRLVQEVPEGAAHALGQYVVLSVRDTGQGIEPEARDRIFEAYFTTKGLGKGTGLGLAQVYGTIRRANG
FVDVQSTPGQGACFTLGMPCP

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=247, Percent_Identity=29.1497975708502, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788549, Length=272, Percent_Identity=27.2058823529412, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI145693157, Length=269, Percent_Identity=28.6245353159851, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1790300, Length=284, Percent_Identity=25.3521126760563, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 45202; Mature: 45202

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNTLMSQDRYRQMVELSPDSIKEVALDGTVRFVNSHGLARIASENAERVVGHPWSSLWP
CCCCCCCHHHHHHHHHCCCHHHHHHHHCCEEEEECCCCHHHHHHCCCHHHCCCCCHHCCH
EEVRDNVHDAIAAAARGECRQFDAECTTPSGERRFWLVSTSPLKNALGEVDAVLAINRDV
HHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHEEECCCH
TERHHAEVALRTLNDSLRSQAGPVSAQTHLSHVVDARMGDSHQRARDLEGELSIALAAQR
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHH
MAEAVAQQAQKGDAVGQLLAGMVHDFNNVLQVASGAVEMVLSRGDMDDKNRVLLGMAESA
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHH
LQQGAAMSKRLLGFARHHPYSPESTDVGRIVQEMMPLLSQAVGSGIVLDLHIEPNLPMAL
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEE
VDPHSLQRAVMNLVVNARDACGAAGTITIAAGSRLVQEVPEGAAHALGQYVVLSVRDTGQ
ECHHHHHHHHHHHHHHCHHHCCCCCEEEEEHHHHHHHHCCCHHHHHCCCEEEEEEECCCC
GIEPEARDRIFEAYFTTKGLGKGTGLGLAQVYGTIRRANGFVDVQSTPGQGACFTLGMPC
CCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCEEECCCCC
P
C
>Mature Secondary Structure
MKNTLMSQDRYRQMVELSPDSIKEVALDGTVRFVNSHGLARIASENAERVVGHPWSSLWP
CCCCCCCHHHHHHHHHCCCHHHHHHHHCCEEEEECCCCHHHHHHCCCHHHCCCCCHHCCH
EEVRDNVHDAIAAAARGECRQFDAECTTPSGERRFWLVSTSPLKNALGEVDAVLAINRDV
HHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHEEECCCH
TERHHAEVALRTLNDSLRSQAGPVSAQTHLSHVVDARMGDSHQRARDLEGELSIALAAQR
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHH
MAEAVAQQAQKGDAVGQLLAGMVHDFNNVLQVASGAVEMVLSRGDMDDKNRVLLGMAESA
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHH
LQQGAAMSKRLLGFARHHPYSPESTDVGRIVQEMMPLLSQAVGSGIVLDLHIEPNLPMAL
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEE
VDPHSLQRAVMNLVVNARDACGAAGTITIAAGSRLVQEVPEGAAHALGQYVVLSVRDTGQ
ECHHHHHHHHHHHHHHCHHHCCCCCEEEEEHHHHHHHHCCCHHHHHCCCEEEEEEECCCC
GIEPEARDRIFEAYFTTKGLGKGTGLGLAQVYGTIRRANGFVDVQSTPGQGACFTLGMPC
CCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCEEECCCCC
P
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA