Click here to switch to the map view.

The map label for this gene is ostA [H]

Identifier: 21243937

GI number: 21243937

Start: 3781628

End: 3782995

Strand: Direct

Name: ostA [H]

Synonym: XAC3211

Alternate gene names: 21243937

Gene position: 3781628-3782995 (Clockwise)

Preceding gene: 21243936

Following gene: 21243938

Centisome position: 73.07

GC content: 62.72

Gene sequence:

>1368_bases
ATGAGTCGTTTGGTGGTGGTATCCAACCGCGTTGCGGTGCCCGGCGAGAACCGCGCCGGTGGCTTGGCGGTTGGCTTGTT
GGCGGCGCTCAAGGAGCGCGGCGGTGTGTGGTTTGGCTGGAGCGGCAAGACCGTGCGCGGCGACAGCGGCGGCATGCACG
AGCAGACCGAAGGCGACATCACCTTCGTCACCATGGACCTCAACAAGCGCGACATCGATTCGTACTACAACGGCTTCGCC
AATCGCACGCTGTGGCCATTACTGCACTTCCGCCTGGACCTGGTCGATTACGACCGCGCCACGCGCGAAGGCTACATGCG
CGTCAATCGGCTGTTTGCCGAAAAACTCGCGCCGCTGCTGAAAGACAGCGACACGCTGTGGATCCACGACTACCACATGA
TTCCGCTCGGCGCGATGCTGCGCGAGCTGGGCGTGGGCTGCAAGATGGGCTTCTTCCTGCACGTGCCGATGCCGTCGGCC
GATCTGGTGCAGGCCATGCCCGATCATGCGCGTTTGTTCAGTACCTTCTACGCATACGACCTGGTCGGCTTCCAGACCCA
GCGCGATGCCGAACGTTTCAAGGCCTATGTGCGCCTATTCGGCGGTGGCCGCATTCTGGAAGGCGATCTGGTGGAAGGCC
CGGGTGGGCGCCGCTTCACCGCCTCTTCGTTCCCGATCGGGATCGATACCGACCTGATTGCCCACCAGGCCAAGGCCTCT
GCCGGCAAGCAGGCGGTGCGTGATCTGCGCGAAAGCCTGCGTGGCCGTCAGTTGGCCATCGGTGTGGACCGCCTGGATTA
TTCCAAGGGATTGCCGGAGCGCTTTCAGGGTTTCGAGCGCTACCTGGAGCGGTATCCGGATCAATCCGGCAGCCTGACCT
ACCTGCAAATTGCGCCGGTTTCGCGCGGCGATGTCACCGAATACCGTCAATTGCGCAGCCAGCTCGAACAGATCGCCGGC
CACATCAACGGCGGACATGCAGAGCCGGACTGGACGCCGCTGCGCTACGTCAACCAGAACTTCAGCCATGCCACGCTGAC
AGGCTTCTATCGTGCGGCCTCGGTGTGTCTGGTCACGCCATTGCGCGACGGCATGAACCTGGTTGCCAAGGAATTCGTGG
CCGCGCAGGATCCGGCAGACCCGGGTGTGCTGGTGTTGTCGCTGTTTGCAGGTGCAGCCGACGAAATGAAGGAAGCGTTG
CTGGTCAACCCGCACGATCTGGATGGCGTGGCCGACGCGATCGCCACAGCGGCAAGCATGCCGCTGGCAAGCCGCATCGA
ACGCTGGCACGCGATGATGGATCACCTGCGCAAGAACAACATCAACCACTGGCGCCAGCGCTATCTGCAAGCGCTCTCTG
AGGTGTAG

Upstream 100 bases:

>100_bases
TCGAGGACGGCGAAGCCTGGGGCAATTTCCCTCAGACCTATTCGCATGTTGGCTTGATCATCGCAGCGATGCGCTTGTCG
CGGAGCTGGCAGGAGGCGTC

Downstream 100 bases:

>100_bases
AGCGACGACCCGTCTCCTACCGGGACTTGTCCTCCTTCAGGCGGACAAGGTCCCCAACAGGCAGAGGACGACATGGCCGC
CATCAGCGTGAAGTCTGCGG

Product: trehalose-6-phosphate synthase

Products: NA

Alternate protein names: Osmoregulatory trehalose synthesis protein A; Trehalose-6-phosphate synthase; UDP-glucose-glucosephosphate glucosyltransferase [H]

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MSRLVVVSNRVAVPGENRAGGLAVGLLAALKERGGVWFGWSGKTVRGDSGGMHEQTEGDITFVTMDLNKRDIDSYYNGFA
NRTLWPLLHFRLDLVDYDRATREGYMRVNRLFAEKLAPLLKDSDTLWIHDYHMIPLGAMLRELGVGCKMGFFLHVPMPSA
DLVQAMPDHARLFSTFYAYDLVGFQTQRDAERFKAYVRLFGGGRILEGDLVEGPGGRRFTASSFPIGIDTDLIAHQAKAS
AGKQAVRDLRESLRGRQLAIGVDRLDYSKGLPERFQGFERYLERYPDQSGSLTYLQIAPVSRGDVTEYRQLRSQLEQIAG
HINGGHAEPDWTPLRYVNQNFSHATLTGFYRAASVCLVTPLRDGMNLVAKEFVAAQDPADPGVLVLSLFAGAADEMKEAL
LVNPHDLDGVADAIATAASMPLASRIERWHAMMDHLRKNNINHWRQRYLQALSEV

Sequences:

>Translated_455_residues
MSRLVVVSNRVAVPGENRAGGLAVGLLAALKERGGVWFGWSGKTVRGDSGGMHEQTEGDITFVTMDLNKRDIDSYYNGFA
NRTLWPLLHFRLDLVDYDRATREGYMRVNRLFAEKLAPLLKDSDTLWIHDYHMIPLGAMLRELGVGCKMGFFLHVPMPSA
DLVQAMPDHARLFSTFYAYDLVGFQTQRDAERFKAYVRLFGGGRILEGDLVEGPGGRRFTASSFPIGIDTDLIAHQAKAS
AGKQAVRDLRESLRGRQLAIGVDRLDYSKGLPERFQGFERYLERYPDQSGSLTYLQIAPVSRGDVTEYRQLRSQLEQIAG
HINGGHAEPDWTPLRYVNQNFSHATLTGFYRAASVCLVTPLRDGMNLVAKEFVAAQDPADPGVLVLSLFAGAADEMKEAL
LVNPHDLDGVADAIATAASMPLASRIERWHAMMDHLRKNNINHWRQRYLQALSEV
>Mature_454_residues
SRLVVVSNRVAVPGENRAGGLAVGLLAALKERGGVWFGWSGKTVRGDSGGMHEQTEGDITFVTMDLNKRDIDSYYNGFAN
RTLWPLLHFRLDLVDYDRATREGYMRVNRLFAEKLAPLLKDSDTLWIHDYHMIPLGAMLRELGVGCKMGFFLHVPMPSAD
LVQAMPDHARLFSTFYAYDLVGFQTQRDAERFKAYVRLFGGGRILEGDLVEGPGGRRFTASSFPIGIDTDLIAHQAKASA
GKQAVRDLRESLRGRQLAIGVDRLDYSKGLPERFQGFERYLERYPDQSGSLTYLQIAPVSRGDVTEYRQLRSQLEQIAGH
INGGHAEPDWTPLRYVNQNFSHATLTGFYRAASVCLVTPLRDGMNLVAKEFVAAQDPADPGVLVLSLFAGAADEMKEALL
VNPHDLDGVADAIATAASMPLASRIERWHAMMDHLRKNNINHWRQRYLQALSEV

Specific function: Catalyzes the transfer of glucose from UDP-glucose to glucose-6-phosphate to form alpha,alpha-1,1 trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor [H]

COG id: COG0380

COG function: function code G; Trehalose-6-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 20 family [H]

Homologues:

Organism=Escherichia coli, GI1788206, Length=458, Percent_Identity=49.3449781659389, Blast_Score=424, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI71987012, Length=434, Percent_Identity=29.0322580645161, Blast_Score=167, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI115533560, Length=358, Percent_Identity=31.8435754189944, Blast_Score=164, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI115533558, Length=358, Percent_Identity=31.8435754189944, Blast_Score=164, Evalue=7e-41,
Organism=Saccharomyces cerevisiae, GI6319602, Length=473, Percent_Identity=31.2896405919662, Blast_Score=271, Evalue=2e-73,
Organism=Saccharomyces cerevisiae, GI6323537, Length=388, Percent_Identity=27.5773195876289, Blast_Score=169, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6323917, Length=386, Percent_Identity=26.1658031088083, Blast_Score=162, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6320279, Length=410, Percent_Identity=23.4146341463415, Blast_Score=147, Evalue=3e-36,
Organism=Drosophila melanogaster, GI19920676, Length=486, Percent_Identity=34.9794238683128, Blast_Score=286, Evalue=1e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001830
- InterPro:   IPR012766 [H]

Pfam domain/function: PF00982 Glyco_transf_20 [H]

EC number: =2.4.1.15 [H]

Molecular weight: Translated: 50814; Mature: 50682

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLVVVSNRVAVPGENRAGGLAVGLLAALKERGGVWFGWSGKTVRGDSGGMHEQTEGDI
CCCEEEEECEEECCCCCCCCHHHHHHHHHHHHCCCEEEECCCCEEECCCCCCCCCCCCCE
TFVTMDLNKRDIDSYYNGFANRTLWPLLHFRLDLVDYDRATREGYMRVNRLFAEKLAPLL
EEEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
KDSDTLWIHDYHMIPLGAMLRELGVGCKMGFFLHVPMPSADLVQAMPDHARLFSTFYAYD
CCCCEEEEEEEECCCHHHHHHHHCCCCEECEEEECCCCCHHHHHHCCHHHHHHHHHHHHH
LVGFQTQRDAERFKAYVRLFGGGRILEGDLVEGPGGRRFTASSFPIGIDTDLIAHQAKAS
HHCCCCHHHHHHHHHHHHHHCCCEEEECCCEECCCCCEEECCCCCCCCCHHHHHHHHHHH
AGKQAVRDLRESLRGRQLAIGVDRLDYSKGLPERFQGFERYLERYPDQSGSLTYLQIAPV
HHHHHHHHHHHHHCCCEEEEEECHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECC
SRGDVTEYRQLRSQLEQIAGHINGGHAEPDWTPLRYVNQNFSHATLTGFYRAASVCLVTP
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHEEEC
LRDGMNLVAKEFVAAQDPADPGVLVLSLFAGAADEMKEALLVNPHDLDGVADAIATAASM
CHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHCC
PLASRIERWHAMMDHLRKNNINHWRQRYLQALSEV
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SRLVVVSNRVAVPGENRAGGLAVGLLAALKERGGVWFGWSGKTVRGDSGGMHEQTEGDI
CCEEEEECEEECCCCCCCCHHHHHHHHHHHHCCCEEEECCCCEEECCCCCCCCCCCCCE
TFVTMDLNKRDIDSYYNGFANRTLWPLLHFRLDLVDYDRATREGYMRVNRLFAEKLAPLL
EEEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
KDSDTLWIHDYHMIPLGAMLRELGVGCKMGFFLHVPMPSADLVQAMPDHARLFSTFYAYD
CCCCEEEEEEEECCCHHHHHHHHCCCCEECEEEECCCCCHHHHHHCCHHHHHHHHHHHHH
LVGFQTQRDAERFKAYVRLFGGGRILEGDLVEGPGGRRFTASSFPIGIDTDLIAHQAKAS
HHCCCCHHHHHHHHHHHHHHCCCEEEECCCEECCCCCEEECCCCCCCCCHHHHHHHHHHH
AGKQAVRDLRESLRGRQLAIGVDRLDYSKGLPERFQGFERYLERYPDQSGSLTYLQIAPV
HHHHHHHHHHHHHCCCEEEEEECHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECC
SRGDVTEYRQLRSQLEQIAGHINGGHAEPDWTPLRYVNQNFSHATLTGFYRAASVCLVTP
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHEEEC
LRDGMNLVAKEFVAAQDPADPGVLVLSLFAGAADEMKEALLVNPHDLDGVADAIATAASM
CHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHCC
PLASRIERWHAMMDHLRKNNINHWRQRYLQALSEV
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA