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The map label for this gene is clpB [H]

Identifier: 21243921

GI number: 21243921

Start: 3758596

End: 3761211

Strand: Reverse

Name: clpB [H]

Synonym: XAC3195

Alternate gene names: 21243921

Gene position: 3761211-3758596 (Counterclockwise)

Preceding gene: 21243922

Following gene: 21243920

Centisome position: 72.67

GC content: 64.03

Gene sequence:

>2616_bases
GTGCCGGCCACCTGTTCAGAGGATCTTCCCATGCGGATGGACAAGCTCACCTCGCGGTTCCAGCAGGCGCTGGCCGACGC
GCAGTCGTTGGCTGTGGGCCGCGACCACAACATCATCGAGCCGGTGCACGTGCTGGCCGCGCTGCTCGACCAGAGCGGCG
GCAGCACCCGACCGCTGCTGTCGCAGGCCGGCGTCAACGTGCCGCTGCTGCGCGAGCGCCTCGGCGAGGCGCTGGACACG
CTGCCCAAGGTGTCCGGGCAGGAAGGCAATCTGTCGATCGGCAACGATCTCAATCGCCTGCTCAACCAGACCGACAAGCT
TGCCCAGCAACATGGCGACGCGTTCATCGCCAGCGAATGGTTCGTGCTGGCCGCCGCCGACGATGCCAGCCCGCTGGGCG
TGGCGTTGCGCGCTGCCGGCGGTGACAAGAAGAAGATCGAAGCGGCCATCGACAAGCTGCGTGGTGGCGAAACCGTGCAG
TCGGAAAACGCCGAAGAACAGCGCCAGGCGCTGGAGAAATACACCATCGATCTGACCGCACGCGCCGAGAGCGGCAAGCT
CGATCCGGTGATCGGCCGCGACGAAGAAATCCGCCGCACCATCCAGGTGCTGCAGCGCCGCACCAAGAACAACCCGGTGC
TGATCGGCGAACCGGGCGTGGGCAAGACCGCCATCGTCGAGGGCCTGGCCCAGCGCATCATCAACGGCGAAGTGCCCGAA
GGCCTGCGCGGCAAGCGCGTGCTGTCGCTGGACATGGGCGCGCTGATTGCCGGTGCCAAGTTTCGCGGCGAGTTCGAAGA
ACGCCTGAAGGCGGTGCTCAGCGACCTGTCCAAGAACGAAGGCCAGATCATCCTGTTCATCGATGAGCTGCACACCATGG
TCGGCGCCGGCAAGGCCGACGGCGCGATGGATGCCGGCAACATGCTCAAGCCGGCGCTGGCGCGCGGTGAGCTGCATTGC
ATCGGCGCCACCACGCTGGACGAATACCGCAAGTACATCGAAAAAGATGCGGCATTGGAGCGCCGCTTCCAGAAAGTGTT
CGTGGGCGAGCCGACGGTGGAAGACACCATTGCGATCCTGCGTGGGCTGAAGGAGCGCTACGCCGTGCATCACGGCGTGG
AGATCACCGACCCGGCCATCGTGGCCGCCGCGACGTTGTCCAACCGCTACATCACCGACCGCCAGTTGCCGGACAAGGCC
ATCGATTTGATGGACGAAGCGGCATCGCGCATCCGCATGGAGATCGACTCCAAGCCGGAGGAGCTCGATCGCCTGGAGCG
CCGCCTGATCCAGCTCAAGATCCAGCGCGAGATGCTCAAGAAGGAAAAGGACGATGCCTCGCGGCAACGGCTGGCCGATC
TGGAAACCGATATCGACAAGCTCGAGCGCGAGTTCTATGACCTCAACGAGCTGTGGAAATCCGAGAAGGCTGCGCTGCAG
GGCACCACCAAGGTCAAGGAGCAGATCGAACACGCCAAGCTGGAACTGGAGGCCGCGCAGCGCCGCCAGGACTACGCCAA
GATGAGCGAGATCCAGTACGGCGTGCTGCCGCAGCTGGAAAAGCAGATGGCGTTGGCCAACGAAGTCGAACACCACGATT
TCAAGCTGGTGCAGGACCGCGTGACCGCCGAGGAAATCGCCGAAGTGGTGTCGCGCTGGACCGGCATTCCGGTCAACAAG
ATGCTCGAAGGCGAGCGCGACAAGCTGTTGCGCATGGAAGACGAACTGCATCATCGCGTGGTCGGGCAGAACGAGGCGAT
CAAGGTGGTGTCCGATGCGGTGCGCCGCTCGCGCGCCGGCCTGTCCGACCCGAACCGCCCCAGTGGCTCGTTCCTGTTCT
TAGGTCCCACCGGCGTGGGTAAGACCGAGCTGTGCAAGGCGCTGGCGGATTTCCTGTTCGACAGCACCGAAGCGATGATT
CGCATCGACATGAGCGAGTTCATGGAGAAGCATTCGGTCGCGCGCCTGATCGGTGCACCTCCTGGCTATGTGGGTTATGA
AGAAGGCGGTTATCTCACCGAGGCCGTGCGTCGTCGTCCGTATTCGCTGATCCTGCTGGACGAAGTGGAAAAGGCGCATC
CGGATGTCTTCAACATCCTGCTGCAGGTGCTCGACGATGGCCGCCTGACCGATGGCCAGGGCCGCACCGTGGACTTCCGC
AATACCGTCATCGTGATGACCTCCAACCTGGGCTCGCACCAGATCCAGGAGCTGTCCGGCGACGATAGCGCCGAGGCGTA
CACGCAGATGAAGGCCGCGGTGATGGGGGTGGTGCAGGCCCACTTCCGCCCGGAGTTCATCAACCGGCTGGACGACATCG
TGGTGTTCCATCCGCTGGACAAGGCGCAGATCAAGTCGATTGCGCGCATCCAGTTGCAAGGCCTGGAAAAACGCCTGGCC
GAGCGCGGCCTCAAGCTGGACCTGGACGATGCGGCGCTGGAGGTGCTGGGCAGTGTCGGCTTCGACCCGGTGTACGGCGC
GCGTCCGCTCAAACGCGCGATCCAATCGCAGGTGGAGAACCCGCTGGCGCAGCAGATCCTGTCGGGCCAGTATCTCAGCG
GCGATAGCGTGCGCGTGCGTGCCGACGGCGGACGGCTGGTGTTTACCAAGGACTGA

Upstream 100 bases:

>100_bases
CACGCCCGCTTGGGTAGCGTCGGCCTGGCCGCTTCCATCTCCAGCACCGGCAAACCTTGAAACCCCGCTCGGCAACCGCA
TCTGCACGGTATCGCCGGCG

Downstream 100 bases:

>100_bases
GCGCGAGGCCCGCACGGCGTAGGAGTGCACTGGGCGCGATGGCTTTACCGGGAACGCCCATCGCGCCCAGGTGCGCTCCT
ACGTCGAGCTGGAACGTGCG

Product: ATP-dependent Clp protease subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 871; Mature: 870

Protein sequence:

>871_residues
MPATCSEDLPMRMDKLTSRFQQALADAQSLAVGRDHNIIEPVHVLAALLDQSGGSTRPLLSQAGVNVPLLRERLGEALDT
LPKVSGQEGNLSIGNDLNRLLNQTDKLAQQHGDAFIASEWFVLAAADDASPLGVALRAAGGDKKKIEAAIDKLRGGETVQ
SENAEEQRQALEKYTIDLTARAESGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGEVPE
GLRGKRVLSLDMGALIAGAKFRGEFEERLKAVLSDLSKNEGQIILFIDELHTMVGAGKADGAMDAGNMLKPALARGELHC
IGATTLDEYRKYIEKDAALERRFQKVFVGEPTVEDTIAILRGLKERYAVHHGVEITDPAIVAAATLSNRYITDRQLPDKA
IDLMDEAASRIRMEIDSKPEELDRLERRLIQLKIQREMLKKEKDDASRQRLADLETDIDKLEREFYDLNELWKSEKAALQ
GTTKVKEQIEHAKLELEAAQRRQDYAKMSEIQYGVLPQLEKQMALANEVEHHDFKLVQDRVTAEEIAEVVSRWTGIPVNK
MLEGERDKLLRMEDELHHRVVGQNEAIKVVSDAVRRSRAGLSDPNRPSGSFLFLGPTGVGKTELCKALADFLFDSTEAMI
RIDMSEFMEKHSVARLIGAPPGYVGYEEGGYLTEAVRRRPYSLILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFR
NTVIVMTSNLGSHQIQELSGDDSAEAYTQMKAAVMGVVQAHFRPEFINRLDDIVVFHPLDKAQIKSIARIQLQGLEKRLA
ERGLKLDLDDAALEVLGSVGFDPVYGARPLKRAIQSQVENPLAQQILSGQYLSGDSVRVRADGGRLVFTKD

Sequences:

>Translated_871_residues
MPATCSEDLPMRMDKLTSRFQQALADAQSLAVGRDHNIIEPVHVLAALLDQSGGSTRPLLSQAGVNVPLLRERLGEALDT
LPKVSGQEGNLSIGNDLNRLLNQTDKLAQQHGDAFIASEWFVLAAADDASPLGVALRAAGGDKKKIEAAIDKLRGGETVQ
SENAEEQRQALEKYTIDLTARAESGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGEVPE
GLRGKRVLSLDMGALIAGAKFRGEFEERLKAVLSDLSKNEGQIILFIDELHTMVGAGKADGAMDAGNMLKPALARGELHC
IGATTLDEYRKYIEKDAALERRFQKVFVGEPTVEDTIAILRGLKERYAVHHGVEITDPAIVAAATLSNRYITDRQLPDKA
IDLMDEAASRIRMEIDSKPEELDRLERRLIQLKIQREMLKKEKDDASRQRLADLETDIDKLEREFYDLNELWKSEKAALQ
GTTKVKEQIEHAKLELEAAQRRQDYAKMSEIQYGVLPQLEKQMALANEVEHHDFKLVQDRVTAEEIAEVVSRWTGIPVNK
MLEGERDKLLRMEDELHHRVVGQNEAIKVVSDAVRRSRAGLSDPNRPSGSFLFLGPTGVGKTELCKALADFLFDSTEAMI
RIDMSEFMEKHSVARLIGAPPGYVGYEEGGYLTEAVRRRPYSLILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFR
NTVIVMTSNLGSHQIQELSGDDSAEAYTQMKAAVMGVVQAHFRPEFINRLDDIVVFHPLDKAQIKSIARIQLQGLEKRLA
ERGLKLDLDDAALEVLGSVGFDPVYGARPLKRAIQSQVENPLAQQILSGQYLSGDSVRVRADGGRLVFTKD
>Mature_870_residues
PATCSEDLPMRMDKLTSRFQQALADAQSLAVGRDHNIIEPVHVLAALLDQSGGSTRPLLSQAGVNVPLLRERLGEALDTL
PKVSGQEGNLSIGNDLNRLLNQTDKLAQQHGDAFIASEWFVLAAADDASPLGVALRAAGGDKKKIEAAIDKLRGGETVQS
ENAEEQRQALEKYTIDLTARAESGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGEVPEG
LRGKRVLSLDMGALIAGAKFRGEFEERLKAVLSDLSKNEGQIILFIDELHTMVGAGKADGAMDAGNMLKPALARGELHCI
GATTLDEYRKYIEKDAALERRFQKVFVGEPTVEDTIAILRGLKERYAVHHGVEITDPAIVAAATLSNRYITDRQLPDKAI
DLMDEAASRIRMEIDSKPEELDRLERRLIQLKIQREMLKKEKDDASRQRLADLETDIDKLEREFYDLNELWKSEKAALQG
TTKVKEQIEHAKLELEAAQRRQDYAKMSEIQYGVLPQLEKQMALANEVEHHDFKLVQDRVTAEEIAEVVSRWTGIPVNKM
LEGERDKLLRMEDELHHRVVGQNEAIKVVSDAVRRSRAGLSDPNRPSGSFLFLGPTGVGKTELCKALADFLFDSTEAMIR
IDMSEFMEKHSVARLIGAPPGYVGYEEGGYLTEAVRRRPYSLILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRN
TVIVMTSNLGSHQIQELSGDDSAEAYTQMKAAVMGVVQAHFRPEFINRLDDIVVFHPLDKAQIKSIARIQLQGLEKRLAE
RGLKLDLDDAALEVLGSVGFDPVYGARPLKRAIQSQVENPLAQQILSGQYLSGDSVRVRADGGRLVFTKD

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=309, Percent_Identity=38.5113268608414, Blast_Score=207, Evalue=4e-53,
Organism=Escherichia coli, GI1788943, Length=857, Percent_Identity=70.24504084014, Blast_Score=1242, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=327, Percent_Identity=43.4250764525994, Blast_Score=268, Evalue=1e-72,
Organism=Saccharomyces cerevisiae, GI6320464, Length=707, Percent_Identity=54.4554455445545, Blast_Score=773, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=867, Percent_Identity=42.4452133794694, Blast_Score=674, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 96621; Mature: 96490

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPATCSEDLPMRMDKLTSRFQQALADAQSLAVGRDHNIIEPVHVLAALLDQSGGSTRPLL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCHH
SQAGVNVPLLRERLGEALDTLPKVSGQEGNLSIGNDLNRLLNQTDKLAQQHGDAFIASEW
HHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCE
FVLAAADDASPLGVALRAAGGDKKKIEAAIDKLRGGETVQSENAEEQRQALEKYTIDLTA
EEEEECCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHEEEEEE
RAESGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGEVPE
ECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCC
GLRGKRVLSLDMGALIAGAKFRGEFEERLKAVLSDLSKNEGQIILFIDELHTMVGAGKAD
CCCCCEEEEECHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCCCC
GAMDAGNMLKPALARGELHCIGATTLDEYRKYIEKDAALERRFQKVFVGEPTVEDTIAIL
CCCCCCCHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
RGLKERYAVHHGVEITDPAIVAAATLSNRYITDRQLPDKAIDLMDEAASRIRMEIDSKPE
HHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHH
ELDRLERRLIQLKIQREMLKKEKDDASRQRLADLETDIDKLEREFYDLNELWKSEKAALQ
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GTTKVKEQIEHAKLELEAAQRRQDYAKMSEIQYGVLPQLEKQMALANEVEHHDFKLVQDR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
VTAEEIAEVVSRWTGIPVNKMLEGERDKLLRMEDELHHRVVGQNEAIKVVSDAVRRSRAG
CCHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
LSDPNRPSGSFLFLGPTGVGKTELCKALADFLFDSTEAMIRIDMSEFMEKHSVARLIGAP
CCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCHHHEEECHHHHHHHHHHHHHHCCC
PGYVGYEEGGYLTEAVRRRPYSLILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFR
CCCCCCCCCCHHHHHHHCCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEEC
NTVIVMTSNLGSHQIQELSGDDSAEAYTQMKAAVMGVVQAHFRPEFINRLDDIVVFHPLD
CEEEEEECCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEEEECCCC
KAQIKSIARIQLQGLEKRLAERGLKLDLDDAALEVLGSVGFDPVYGARPLKRAIQSQVEN
HHHHHHHHHHHHHHHHHHHHHCCCEECCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCC
PLAQQILSGQYLSGDSVRVRADGGRLVFTKD
HHHHHHHCCCCCCCCCEEEEECCCEEEEECC
>Mature Secondary Structure 
PATCSEDLPMRMDKLTSRFQQALADAQSLAVGRDHNIIEPVHVLAALLDQSGGSTRPLL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCHH
SQAGVNVPLLRERLGEALDTLPKVSGQEGNLSIGNDLNRLLNQTDKLAQQHGDAFIASEW
HHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCE
FVLAAADDASPLGVALRAAGGDKKKIEAAIDKLRGGETVQSENAEEQRQALEKYTIDLTA
EEEEECCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHEEEEEE
RAESGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGEVPE
ECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCC
GLRGKRVLSLDMGALIAGAKFRGEFEERLKAVLSDLSKNEGQIILFIDELHTMVGAGKAD
CCCCCEEEEECHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCCCC
GAMDAGNMLKPALARGELHCIGATTLDEYRKYIEKDAALERRFQKVFVGEPTVEDTIAIL
CCCCCCCHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
RGLKERYAVHHGVEITDPAIVAAATLSNRYITDRQLPDKAIDLMDEAASRIRMEIDSKPE
HHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHH
ELDRLERRLIQLKIQREMLKKEKDDASRQRLADLETDIDKLEREFYDLNELWKSEKAALQ
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GTTKVKEQIEHAKLELEAAQRRQDYAKMSEIQYGVLPQLEKQMALANEVEHHDFKLVQDR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
VTAEEIAEVVSRWTGIPVNKMLEGERDKLLRMEDELHHRVVGQNEAIKVVSDAVRRSRAG
CCHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
LSDPNRPSGSFLFLGPTGVGKTELCKALADFLFDSTEAMIRIDMSEFMEKHSVARLIGAP
CCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCHHHEEECHHHHHHHHHHHHHHCCC
PGYVGYEEGGYLTEAVRRRPYSLILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFR
CCCCCCCCCCHHHHHHHCCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEEC
NTVIVMTSNLGSHQIQELSGDDSAEAYTQMKAAVMGVVQAHFRPEFINRLDDIVVFHPLD
CEEEEEECCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEEEECCCC
KAQIKSIARIQLQGLEKRLAERGLKLDLDDAALEVLGSVGFDPVYGARPLKRAIQSQVEN
HHHHHHHHHHHHHHHHHHHHHCCCEECCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCC
PLAQQILSGQYLSGDSVRVRADGGRLVFTKD
HHHHHHHCCCCCCCCCEEEEECCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]