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The map label for this gene is cobC [C]

Identifier: 21243911

GI number: 21243911

Start: 3748476

End: 3749090

Strand: Reverse

Name: cobC [C]

Synonym: XAC3185

Alternate gene names: 21243911

Gene position: 3749090-3748476 (Counterclockwise)

Preceding gene: 21243912

Following gene: 21243910

Centisome position: 72.44

GC content: 67.48

Gene sequence:

>615_bases
ATGAGCGCGCAGATCACCTTGTTGCGGCATGGCGACACGGGGCAACGCAGTTATCGCGGCCAGCTCGACGACCCGCTCAC
CGAGCTGGGCTGGCAGCAATTACGTGCGGCCACTGCCGATGGCGTGTGGGACGCAGTCGTGACATCCACGTTGCAGCGCT
GCGCTTTGTTCGCCACCGAGCTCGCCCAAGCGCGTGCCATGCCGCTGCAGCTGGACCCGCGCCTGCGCGAATATCACTTT
GGCCGCTGGCAGGGCGTGCCGGTGGCGGATATCGACCGCGACGACGGCGAGGCGCTCGGCCGGTTCTGGGCCGACCCGGT
AGGCCACCCGCCACCGCAAGCCGAACCGTTCGCAGACTTCTGTGCACGCTTGTCTGCGGCACTGGACGACATCGTGGCGC
GCTATCCGGCGCAACGCGTGCTGGTGGTCACCCACGGCGGCGCCATCCGTGCCTTGCAGTGCCTGGTTGCCGGTAATGGT
TTCGGCCGAATGACCGAACTGGCAGTGCCGCATGCGTCCCTGCATCCGCTGGCCTGGCCGCCAACCGACGCGGCTGGCGC
CTTTGGGTCGCCGGTTTCATCCACTGCATTGCCACCGGCGCACGACACAGAATGA

Upstream 100 bases:

>100_bases
GCGAAGCCAGCGGCGCGGCGGTGGCGATTCCGCTACTGCGCAGCGCCTGCGCCTTGCACAACGGCATGGCGACCTTCGCC
GAAGCCGGGGTGTCGGACGC

Downstream 100 bases:

>100_bases
TCGACGGGTTGCTGGCGGCGATCGGGTTTCTGACCCGTATTCCGGTGCCCGCCCGGGTGTTCACGCGCGCAGGCGCGCAG
GCGCGCTCGCTTTGCTGGTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MSAQITLLRHGDTGQRSYRGQLDDPLTELGWQQLRAATADGVWDAVVTSTLQRCALFATELAQARAMPLQLDPRLREYHF
GRWQGVPVADIDRDDGEALGRFWADPVGHPPPQAEPFADFCARLSAALDDIVARYPAQRVLVVTHGGAIRALQCLVAGNG
FGRMTELAVPHASLHPLAWPPTDAAGAFGSPVSSTALPPAHDTE

Sequences:

>Translated_204_residues
MSAQITLLRHGDTGQRSYRGQLDDPLTELGWQQLRAATADGVWDAVVTSTLQRCALFATELAQARAMPLQLDPRLREYHF
GRWQGVPVADIDRDDGEALGRFWADPVGHPPPQAEPFADFCARLSAALDDIVARYPAQRVLVVTHGGAIRALQCLVAGNG
FGRMTELAVPHASLHPLAWPPTDAAGAFGSPVSSTALPPAHDTE
>Mature_203_residues
SAQITLLRHGDTGQRSYRGQLDDPLTELGWQQLRAATADGVWDAVVTSTLQRCALFATELAQARAMPLQLDPRLREYHFG
RWQGVPVADIDRDDGEALGRFWADPVGHPPPQAEPFADFCARLSAALDDIVARYPAQRVLVVTHGGAIRALQCLVAGNGF
GRMTELAVPHASLHPLAWPPTDAAGAFGSPVSSTALPPAHDTE

Specific function: Converts N1-(5-Phospho-Alpha-D-Ribosyl)-5,6- Dimethylbenzimidazole Into N1-Alpha-D-Ribosyl-5,6- Dimethylbenzimidazole; Involved In The Assembly Of The Nucleotide Loop Of Cobalamin. [C]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase H domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR012337
- InterPro:   IPR014636
- InterPro:   IPR002156 [H]

Pfam domain/function: PF00300 PGAM; PF00075 RnaseH [H]

EC number: 3.1.3.73 [C]

Molecular weight: Translated: 21993; Mature: 21862

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAQITLLRHGDTGQRSYRGQLDDPLTELGWQQLRAATADGVWDAVVTSTLQRCALFATE
CCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LAQARAMPLQLDPRLREYHFGRWQGVPVADIDRDDGEALGRFWADPVGHPPPQAEPFADF
HHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHH
CARLSAALDDIVARYPAQRVLVVTHGGAIRALQCLVAGNGFGRMTELAVPHASLHPLAWP
HHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCC
PTDAAGAFGSPVSSTALPPAHDTE
CCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SAQITLLRHGDTGQRSYRGQLDDPLTELGWQQLRAATADGVWDAVVTSTLQRCALFATE
CCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LAQARAMPLQLDPRLREYHFGRWQGVPVADIDRDDGEALGRFWADPVGHPPPQAEPFADF
HHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHH
CARLSAALDDIVARYPAQRVLVVTHGGAIRALQCLVAGNGFGRMTELAVPHASLHPLAWP
HHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCC
PTDAAGAFGSPVSSTALPPAHDTE
CCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]