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The map label for this gene is cutC [H]

Identifier: 21243818

GI number: 21243818

Start: 3629583

End: 3630380

Strand: Reverse

Name: cutC [H]

Synonym: XAC3091

Alternate gene names: 21243818

Gene position: 3630380-3629583 (Counterclockwise)

Preceding gene: 77748696

Following gene: 21243814

Centisome position: 70.14

GC content: 68.8

Gene sequence:

>798_bases
GTGCGACGCGCAGCGGCAGGATCTGCTGGTGCCTGGCGAGAGCCATTACACCAGCGAGCCGGCAGCATGAGCGCGGTGGG
ATTGGAAGTGGCTGCCGATTCGGTGGCCTCGGCATTGGCCGCGCAAGCAGGCGGTGCGATGCGCGTGGAGCTGTGCGGCG
GGCTGGATGGCGGCGGGCTGACGCCGTCGTTCGGCACGTTGGCGGTGGTGCGCGAGCGTTTGCGGATTCCGCTGTATGTG
CTGATTCGTCCGCGCGTGGGCGACTTCGTGTTCGACGCCGCCGAAGTCGAGGTGATGCGCCGCGATGTGGAGCAGTGCGT
CCGGCTGGGATGCGATGGCGTGGTCCTTGGCGCGCTGGACCGGCATGGGCAGGTCGATCTGGCGACAATGCGCGTGTTGA
TGCAGGCAGCAGGGTCGTTGGGGGTGACGTTTCATCGCGCGATCGATGTCAGTGCCGACCCGTCGCGCGTGCTGGAGGAT
GCGATCGCGCTGGGGTGCGAGCGGGTGCTGACCTCGGGCGCACGTGCGAGTGCGCTGGAGGGCATCGACACCATCGCCGC
GTTGGTGCGGCAGGCAGCCGGGCGCATCGGCATCATGCCCGGTGCCGGGCTTTCCGAGCACAACATCCGCGCCCTACGGC
AGCACACCGGCGCCCACGAATTCCATGCGTCGGCGCGTGGCGTGATCGCCGCCCAGGTGCCGTCGCCGCACCCCTATATC
CGCGATCTGGGCGGGGACTACCAGCGGACCGATACCGCGCGGGTACAACGGATGGTGGACGCGTTGCAGCAAGCGTGA

Upstream 100 bases:

>100_bases
AGCCGGAGCTGACGCGCACATTGCAGGTCGGCTTTCTGGCAATGAACAAGCGCGGCGAAGTGGGAGCGTTCGCGATCCAG
AAGGGCTTCAGTTACGCGGT

Downstream 100 bases:

>100_bases
AACGCGCGCAACGCCCCGTTCGGCCGGGGATGCGCCGCCTGACTTGCGCAGGCACATGACGGCGATGCTCGATTGGCGAC
GGCGCATCTCGTGTTTGCCC

Product: copper homeostasis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MRRAAAGSAGAWREPLHQRAGSMSAVGLEVAADSVASALAAQAGGAMRVELCGGLDGGGLTPSFGTLAVVRERLRIPLYV
LIRPRVGDFVFDAAEVEVMRRDVEQCVRLGCDGVVLGALDRHGQVDLATMRVLMQAAGSLGVTFHRAIDVSADPSRVLED
AIALGCERVLTSGARASALEGIDTIAALVRQAAGRIGIMPGAGLSEHNIRALRQHTGAHEFHASARGVIAAQVPSPHPYI
RDLGGDYQRTDTARVQRMVDALQQA

Sequences:

>Translated_265_residues
MRRAAAGSAGAWREPLHQRAGSMSAVGLEVAADSVASALAAQAGGAMRVELCGGLDGGGLTPSFGTLAVVRERLRIPLYV
LIRPRVGDFVFDAAEVEVMRRDVEQCVRLGCDGVVLGALDRHGQVDLATMRVLMQAAGSLGVTFHRAIDVSADPSRVLED
AIALGCERVLTSGARASALEGIDTIAALVRQAAGRIGIMPGAGLSEHNIRALRQHTGAHEFHASARGVIAAQVPSPHPYI
RDLGGDYQRTDTARVQRMVDALQQA
>Mature_265_residues
MRRAAAGSAGAWREPLHQRAGSMSAVGLEVAADSVASALAAQAGGAMRVELCGGLDGGGLTPSFGTLAVVRERLRIPLYV
LIRPRVGDFVFDAAEVEVMRRDVEQCVRLGCDGVVLGALDRHGQVDLATMRVLMQAAGSLGVTFHRAIDVSADPSRVLED
AIALGCERVLTSGARASALEGIDTIAALVRQAAGRIGIMPGAGLSEHNIRALRQHTGAHEFHASARGVIAAQVPSPHPYI
RDLGGDYQRTDTARVQRMVDALQQA

Specific function: Involved in copper homeostasis [H]

COG id: COG3142

COG function: function code P; Uncharacterized protein involved in copper resistance

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CutC family [H]

Homologues:

Organism=Homo sapiens, GI148596990, Length=226, Percent_Identity=46.0176991150442, Blast_Score=195, Evalue=3e-50,
Organism=Escherichia coli, GI87081995, Length=198, Percent_Identity=44.4444444444444, Blast_Score=150, Evalue=8e-38,
Organism=Caenorhabditis elegans, GI17556905, Length=205, Percent_Identity=40.9756097560976, Blast_Score=154, Evalue=4e-38,
Organism=Drosophila melanogaster, GI21355415, Length=212, Percent_Identity=39.1509433962264, Blast_Score=147, Evalue=9e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005627 [H]

Pfam domain/function: PF03932 CutC [H]

EC number: NA

Molecular weight: Translated: 27827; Mature: 27827

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRAAAGSAGAWREPLHQRAGSMSAVGLEVAADSVASALAAQAGGAMRVELCGGLDGGGL
CCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCC
TPSFGTLAVVRERLRIPLYVLIRPRVGDFVFDAAEVEVMRRDVEQCVRLGCDGVVLGALD
CCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCC
RHGQVDLATMRVLMQAAGSLGVTFHRAIDVSADPSRVLEDAIALGCERVLTSGARASALE
CCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHH
GIDTIAALVRQAAGRIGIMPGAGLSEHNIRALRQHTGAHEFHASARGVIAAQVPSPHPYI
HHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHCCCHHHHHHCCCEEEEECCCCCHHH
RDLGGDYQRTDTARVQRMVDALQQA
HHCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRRAAAGSAGAWREPLHQRAGSMSAVGLEVAADSVASALAAQAGGAMRVELCGGLDGGGL
CCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCC
TPSFGTLAVVRERLRIPLYVLIRPRVGDFVFDAAEVEVMRRDVEQCVRLGCDGVVLGALD
CCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCC
RHGQVDLATMRVLMQAAGSLGVTFHRAIDVSADPSRVLEDAIALGCERVLTSGARASALE
CCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHH
GIDTIAALVRQAAGRIGIMPGAGLSEHNIRALRQHTGAHEFHASARGVIAAQVPSPHPYI
HHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHCCCHHHHHHCCCEEEEECCCCCHHH
RDLGGDYQRTDTARVQRMVDALQQA
HHCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]