Click here to switch to the map view.

The map label for this gene is hly3 [C]

Identifier: 21243770

GI number: 21243770

Start: 3560872

End: 3561516

Strand: Direct

Name: hly3 [C]

Synonym: XAC3043

Alternate gene names: 21243770

Gene position: 3560872-3561516 (Clockwise)

Preceding gene: 21243769

Following gene: 21243771

Centisome position: 68.8

GC content: 62.17

Gene sequence:

>645_bases
ATGAACGCAGACGCCTCCCCCTCGACCGACCTGCGCGACGAAATCGCCAGCGCCGTCACGCACGGCCTGGGGGCGATTGC
CGCACTGGCCGGTGGTTCGGTGCTGATCACGCTGGCCGCCATCTATGGCGATGGCTGGCAACTGGCCACCGCCATCGTGT
TCAGTGCCACGCTGGTATTGCTCTACGTCGCCTCCACGCTGTTCCATGCCATTCCGCATCCGGGCGCCAAGGCGCGCCTG
CAGGTGCTCGATCATTGCGCGATCTATCTGCTGATCGCCGGCACCTACACACCGTTTACGTTGATCAATCTACGCGGCCC
GTGGGGCTGGGGATTGTTCGCCGCCATCTGGACGATCGCCGCCGCCGGGGTGATCTTCAAACTGTTTTTTACAGGTCGCT
TTCGATTGCTCTCGACGGTGCTGTATCTGGCGATGGGCTGGCTGATCATCGTGGCCATCGAGCCGCTGCTGCGCTCTGTC
GACACCTGGTCGCTGTGCTGGCTGCTGGCTGGCGGGCTCTTCTACACCTTGGGCACGTATTTCTATCAACGCGACACCCA
GCGTTACTTCCACGCCATCTGGCATCTGTTCGTGCTCGCCGGTAGCGCTTGCCACTTCGTTGCGGTGATTGCGCAGGTGA
TGTGA

Upstream 100 bases:

>100_bases
TGCGCATGTCAAGGCGGTCGATTGACCTGCGCGTGACCTGCAGCAAGCGTGCGGGACCGCTGGCGATGCGAATCGCTCGC
AATTGCGGTACCTTTTTGGC

Downstream 100 bases:

>100_bases
TCTGTGACCAACAGCGCGTTCGCGCGCCGTGCACGAGCCATCGCCAACCATTGCGCACGTGAATAACGTGCCCTCCTCTC
CCGCTGCTTCGCCCACCCGC

Product: hemolysin III

Products: NA

Alternate protein names: Hemolysin III; Hly-III [H]

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MNADASPSTDLRDEIASAVTHGLGAIAALAGGSVLITLAAIYGDGWQLATAIVFSATLVLLYVASTLFHAIPHPGAKARL
QVLDHCAIYLLIAGTYTPFTLINLRGPWGWGLFAAIWTIAAAGVIFKLFFTGRFRLLSTVLYLAMGWLIIVAIEPLLRSV
DTWSLCWLLAGGLFYTLGTYFYQRDTQRYFHAIWHLFVLAGSACHFVAVIAQVM

Sequences:

>Translated_214_residues
MNADASPSTDLRDEIASAVTHGLGAIAALAGGSVLITLAAIYGDGWQLATAIVFSATLVLLYVASTLFHAIPHPGAKARL
QVLDHCAIYLLIAGTYTPFTLINLRGPWGWGLFAAIWTIAAAGVIFKLFFTGRFRLLSTVLYLAMGWLIIVAIEPLLRSV
DTWSLCWLLAGGLFYTLGTYFYQRDTQRYFHAIWHLFVLAGSACHFVAVIAQVM
>Mature_214_residues
MNADASPSTDLRDEIASAVTHGLGAIAALAGGSVLITLAAIYGDGWQLATAIVFSATLVLLYVASTLFHAIPHPGAKARL
QVLDHCAIYLLIAGTYTPFTLINLRGPWGWGLFAAIWTIAAAGVIFKLFFTGRFRLLSTVLYLAMGWLIIVAIEPLLRSV
DTWSLCWLLAGGLFYTLGTYFYQRDTQRYFHAIWHLFVLAGSACHFVAVIAQVM

Specific function: Unknown

COG id: COG1272

COG function: function code R; Predicted membrane protein, hemolysin III homolog

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0073 (Hly-III) family [H]

Homologues:

Organism=Homo sapiens, GI154759275, Length=205, Percent_Identity=32.1951219512195, Blast_Score=106, Evalue=1e-23,
Organism=Homo sapiens, GI154759277, Length=229, Percent_Identity=28.82096069869, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI52630445, Length=218, Percent_Identity=29.3577981651376, Blast_Score=91, Evalue=9e-19,
Organism=Escherichia coli, GI1789266, Length=204, Percent_Identity=47.0588235294118, Blast_Score=171, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI71996356, Length=211, Percent_Identity=31.7535545023697, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24640324, Length=244, Percent_Identity=29.9180327868852, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004254
- InterPro:   IPR005744 [H]

Pfam domain/function: PF03006 HlyIII [H]

EC number: NA

Molecular weight: Translated: 23297; Mature: 23297

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNADASPSTDLRDEIASAVTHGLGAIAALAGGSVLITLAAIYGDGWQLATAIVFSATLVL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LYVASTLFHAIPHPGAKARLQVLDHCAIYLLIAGTYTPFTLINLRGPWGWGLFAAIWTIA
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHH
AAGVIFKLFFTGRFRLLSTVLYLAMGWLIIVAIEPLLRSVDTWSLCWLLAGGLFYTLGTY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
FYQRDTQRYFHAIWHLFVLAGSACHFVAVIAQVM
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHC
>Mature Secondary Structure
MNADASPSTDLRDEIASAVTHGLGAIAALAGGSVLITLAAIYGDGWQLATAIVFSATLVL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LYVASTLFHAIPHPGAKARLQVLDHCAIYLLIAGTYTPFTLINLRGPWGWGLFAAIWTIA
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHH
AAGVIFKLFFTGRFRLLSTVLYLAMGWLIIVAIEPLLRSVDTWSLCWLLAGGLFYTLGTY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
FYQRDTQRYFHAIWHLFVLAGSACHFVAVIAQVM
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7495855 [H]