Click here to switch to the map view.

The map label for this gene is puuP [H]

Identifier: 21243716

GI number: 21243716

Start: 3494767

End: 3496149

Strand: Direct

Name: puuP [H]

Synonym: XAC2989

Alternate gene names: 21243716

Gene position: 3494767-3496149 (Clockwise)

Preceding gene: 21243708

Following gene: 21243718

Centisome position: 67.52

GC content: 64.14

Gene sequence:

>1383_bases
ATGATCGACACACCACGCCGCGACGATGCGGCCACGCTGGAACGCTTCGGCTACGCACAGGAGCTCAAGCGGCAGCTCAC
GCTCAAGGATCTGTTGATCTACGGGCTGGTGTGCATGGTGCCCACGGCGCCGTTCTCGATCTTCGGCGGCGTCTTCGACA
TCAGTGCCGGGATGGTGCCGCTGACCTACCTGGTCGGCTTCGTGGCGATGCTGTTCACCGCACTGAGCTACCAGCAGATG
TCGCAGGCATTTCCGGTGGCGGGTTCGGTGTATGCCTATGTCGGGCGCGGGCTGAGCAGCGGCATGGGCTTTCTGGCCGG
CTGGGCGATTCTGCTCGACTACCTGCTGGTGCCGACCCTGCTGTATGTGGTCGGCGCCAATGCGATGCATACCGTGTTGC
CGGCGGTACCCCAGCCGGCGTGGATTGCGTTCTTCGTGGTGCTCAACACGGTGGTGAACCTGCGTGGCATCGAAACCACC
GCACGCGCCAATCGCTTTTTCCTGCTTGCGCAGTTGCTGGTGTTGGCGGTGTTCGTGGTGCTGGCGACGCTGGCGATCCA
GCGCGGCGTCAATGGGGCGCACTGGAGCTGGCGCCCGCTGTATAACCCACAAGCGTTTTCTCCGCAGTTGATCTTCAGCG
CGTTGTCGGTGGCGGTGGTGTCGTTCCTCGGCTTCGATGCAATCTCCACCATGTCCGAGGAAGCGCGCGGCGGCAACCGT
GTGGTGGGACGTGCAACCTTGCTGGCATTGCTGATCGTGGCAGGGCTGTTCGTCTTGCAAACCTGGCTGGCGGCATTGCT
GCAGCCCACCCTGCAGCGCTACCCAAGCGCGCAGGCATCCAACGATGCGTTCTTCGAGATCGGGCGATTGATCGCCGGGC
CATGGCTGCAGATCGTCATTGCGCTCACCGTGGCGATCAGCGCGGCAATCGCCAATTCATTGGTTGCACAGGCGGCCACC
TCGCGGCTGTTGTTCGCCATGGCGCGCGACCGGCAGTTGCCGGGCTTTCTGCGCTACATCCACCCACGCACCGGCGTGCC
GCAGCGCGCGATCCTGCTGGTGGCGGGCCTGAGTCTGGTACTGGGCGAAGTCTTCGTCGGGCAGATCGCGCTGCTGTCGT
CGCTGTGCAACGTCGGCGCACTGACCGCCTTCGTGCTGCTGCATATCGCAGTGCTGTGGCACTTCCGCACCCAGGGCCGG
CATGTGCTGCATGGCGCGGTGCCCTTGATCGGGATCGTCATCCTGGCCTACGTGCTGCTCAATGCCGATCTGCATGCACA
ACTGGGCGGCGCTGCGTGGATGGCGGTAGGGCTGGCGGTACTGGCGTTCTTGAAACTCAGCGGACGCTCCACCGAATTCC
GCGCCAGCGACGCGCTGGAATAG

Upstream 100 bases:

>100_bases
ATCGTCACAATGCCGGTCGTATGGCGGCAGCATGGCACCGGCGTTCAGGTCGTCCAGGCGCTTGCGCTGCGTGCCGGCAT
TCCTTTCAGCGGACACCTGC

Downstream 100 bases:

>100_bases
CCGGCACAGCAGCACCGTCTGTTGTGCCGGCTTACTCCTGGCCCACCGGTGCCGCGGAGCGCGACGGGTCAAATTCGTGC
TGGGCAACCTCAAACGCGTC

Product: amino acid transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MIDTPRRDDAATLERFGYAQELKRQLTLKDLLIYGLVCMVPTAPFSIFGGVFDISAGMVPLTYLVGFVAMLFTALSYQQM
SQAFPVAGSVYAYVGRGLSSGMGFLAGWAILLDYLLVPTLLYVVGANAMHTVLPAVPQPAWIAFFVVLNTVVNLRGIETT
ARANRFFLLAQLLVLAVFVVLATLAIQRGVNGAHWSWRPLYNPQAFSPQLIFSALSVAVVSFLGFDAISTMSEEARGGNR
VVGRATLLALLIVAGLFVLQTWLAALLQPTLQRYPSAQASNDAFFEIGRLIAGPWLQIVIALTVAISAAIANSLVAQAAT
SRLLFAMARDRQLPGFLRYIHPRTGVPQRAILLVAGLSLVLGEVFVGQIALLSSLCNVGALTAFVLLHIAVLWHFRTQGR
HVLHGAVPLIGIVILAYVLLNADLHAQLGGAAWMAVGLAVLAFLKLSGRSTEFRASDALE

Sequences:

>Translated_460_residues
MIDTPRRDDAATLERFGYAQELKRQLTLKDLLIYGLVCMVPTAPFSIFGGVFDISAGMVPLTYLVGFVAMLFTALSYQQM
SQAFPVAGSVYAYVGRGLSSGMGFLAGWAILLDYLLVPTLLYVVGANAMHTVLPAVPQPAWIAFFVVLNTVVNLRGIETT
ARANRFFLLAQLLVLAVFVVLATLAIQRGVNGAHWSWRPLYNPQAFSPQLIFSALSVAVVSFLGFDAISTMSEEARGGNR
VVGRATLLALLIVAGLFVLQTWLAALLQPTLQRYPSAQASNDAFFEIGRLIAGPWLQIVIALTVAISAAIANSLVAQAAT
SRLLFAMARDRQLPGFLRYIHPRTGVPQRAILLVAGLSLVLGEVFVGQIALLSSLCNVGALTAFVLLHIAVLWHFRTQGR
HVLHGAVPLIGIVILAYVLLNADLHAQLGGAAWMAVGLAVLAFLKLSGRSTEFRASDALE
>Mature_460_residues
MIDTPRRDDAATLERFGYAQELKRQLTLKDLLIYGLVCMVPTAPFSIFGGVFDISAGMVPLTYLVGFVAMLFTALSYQQM
SQAFPVAGSVYAYVGRGLSSGMGFLAGWAILLDYLLVPTLLYVVGANAMHTVLPAVPQPAWIAFFVVLNTVVNLRGIETT
ARANRFFLLAQLLVLAVFVVLATLAIQRGVNGAHWSWRPLYNPQAFSPQLIFSALSVAVVSFLGFDAISTMSEEARGGNR
VVGRATLLALLIVAGLFVLQTWLAALLQPTLQRYPSAQASNDAFFEIGRLIAGPWLQIVIALTVAISAAIANSLVAQAAT
SRLLFAMARDRQLPGFLRYIHPRTGVPQRAILLVAGLSLVLGEVFVGQIALLSSLCNVGALTAFVLLHIAVLWHFRTQGR
HVLHGAVPLIGIVILAYVLLNADLHAQLGGAAWMAVGLAVLAFLKLSGRSTEFRASDALE

Specific function: Imports putrescine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI87081869, Length=446, Percent_Identity=29.8206278026906, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI87082023, Length=439, Percent_Identity=30.751708428246, Blast_Score=195, Evalue=5e-51,
Organism=Escherichia coli, GI1788480, Length=403, Percent_Identity=24.0694789081886, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17532491, Length=401, Percent_Identity=26.4339152119701, Blast_Score=85, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17533459, Length=424, Percent_Identity=24.5283018867925, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24667468, Length=398, Percent_Identity=26.6331658291457, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21357367, Length=344, Percent_Identity=24.7093023255814, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24666159, Length=420, Percent_Identity=24.047619047619, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221512776, Length=420, Percent_Identity=24.047619047619, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49501; Mature: 49501

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure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CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]