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The map label for this gene is hda [H]

Identifier: 21243683

GI number: 21243683

Start: 3461557

End: 3462258

Strand: Reverse

Name: hda [H]

Synonym: XAC2956

Alternate gene names: 21243683

Gene position: 3462258-3461557 (Counterclockwise)

Preceding gene: 21243684

Following gene: 21243678

Centisome position: 66.9

GC content: 69.23

Gene sequence:

>702_bases
GTGAGTGTTCCGCAGTTGCCGCTGGCGTTGCGCGCGCCACCCGATCAGCGTTTCGACAGTTACATCGCCGCGCCCGACGG
CCTGCTTGCGCAATTGCAGGCGCTGGCTGCGGGGCAGGTGAGCGATTGGCTGTATCTCTCCGGCCCCGCCGGCACCGGCA
AGACGCATCTGGCGCTATCGCTGTGCGCCGCCGCCGAGCAGGCCGGGCGCACGCCGGCGTATCTGCCGCTGCAGGCGGCC
GCCGGCCGCTTGCGCGATGCGCTCGAAGCGCTGGAAGGCCGCAGCCTGGTCGCCCTGGATGGCGTGGAAAGCATCGCCGG
CCAACGCGACGACGAAGTGGCGTTGTTCGATTTCCACAATCGCGCGCGCGCGGCCGGCATCACGCTGTTGTACACCGCGC
GACAGATGCCCGATGGACTGGCGTTGGTGTTGCCGGACCTGCGTTCGCGGTTGGCGCAATGCATCCGGATCGGGTTGCCC
GTGCTCGACGATGCGGCACGCGCGGCGGTGCTGCGCGACCGCGCGCAGCGTCGCGGCCTGGCGCTGGACGAAGCGGCGAT
CGACTGGCTGCTGACCCACAGCGAGCGTGAATTGGCGGCGCTGGTGGCCTTGCTGGATCGCCTGGATCGCGAATCATTGG
CCGCAAAACGCCGCATCACCGTGCCGTTCCTTCGGCGTGTGCTTGAGGATCGCGGCTCGTAG

Upstream 100 bases:

>100_bases
CGCGCAGCGATCTGTATGCGGGCGAGCGCGCCGGCATCGTGCTGCGGTCCACGCCCGAGCGCAGCGTGATCATCGACCCC
AGCAAGGATGCAGATCGGTT

Downstream 100 bases:

>100_bases
CGCTGCTGATGTGCGGATGTTCTGCAGAGCCTTGCCCGCACACCGTCGCGGGACACGCTGCAGGTAGGTCCATCCAGCTC
CGTGGCGGCATCTGTGCCGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MSVPQLPLALRAPPDQRFDSYIAAPDGLLAQLQALAAGQVSDWLYLSGPAGTGKTHLALSLCAAAEQAGRTPAYLPLQAA
AGRLRDALEALEGRSLVALDGVESIAGQRDDEVALFDFHNRARAAGITLLYTARQMPDGLALVLPDLRSRLAQCIRIGLP
VLDDAARAAVLRDRAQRRGLALDEAAIDWLLTHSERELAALVALLDRLDRESLAAKRRITVPFLRRVLEDRGS

Sequences:

>Translated_233_residues
MSVPQLPLALRAPPDQRFDSYIAAPDGLLAQLQALAAGQVSDWLYLSGPAGTGKTHLALSLCAAAEQAGRTPAYLPLQAA
AGRLRDALEALEGRSLVALDGVESIAGQRDDEVALFDFHNRARAAGITLLYTARQMPDGLALVLPDLRSRLAQCIRIGLP
VLDDAARAAVLRDRAQRRGLALDEAAIDWLLTHSERELAALVALLDRLDRESLAAKRRITVPFLRRVLEDRGS
>Mature_232_residues
SVPQLPLALRAPPDQRFDSYIAAPDGLLAQLQALAAGQVSDWLYLSGPAGTGKTHLALSLCAAAEQAGRTPAYLPLQAAA
GRLRDALEALEGRSLVALDGVESIAGQRDDEVALFDFHNRARAAGITLLYTARQMPDGLALVLPDLRSRLAQCIRIGLPV
LDDAARAAVLRDRAQRRGLALDEAAIDWLLTHSERELAALVALLDRLDRESLAAKRRITVPFLRRVLEDRGS

Specific function: Mediates the interactions of dnaA with the beta subunit sliding clamp, promoting hydrolysis of dnaA-bound ATP. It is essential for the control of initiation of DNA replication by inhibiting reinitiation of replication [H]

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family. HdA subfamily [H]

Homologues:

Organism=Escherichia coli, GI226510964, Length=232, Percent_Identity=37.5, Blast_Score=129, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020591
- InterPro:   IPR017788
- InterPro:   IPR013317
- InterPro:   IPR022864 [H]

Pfam domain/function: PF00308 Bac_DnaA [H]

EC number: NA

Molecular weight: Translated: 25138; Mature: 25007

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVPQLPLALRAPPDQRFDSYIAAPDGLLAQLQALAAGQVSDWLYLSGPAGTGKTHLALS
CCCCCCCEEEECCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHH
LCAAAEQAGRTPAYLPLQAAAGRLRDALEALEGRSLVALDGVESIAGQRDDEVALFDFHN
HHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHCCCCEEEECCHHHHCCCCCCCEEEEECCC
RARAAGITLLYTARQMPDGLALVLPDLRSRLAQCIRIGLPVLDDAARAAVLRDRAQRRGL
HHHHHCEEEEEEHHHCCCCCEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
ALDEAAIDWLLTHSERELAALVALLDRLDRESLAAKRRITVPFLRRVLEDRGS
CHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
SVPQLPLALRAPPDQRFDSYIAAPDGLLAQLQALAAGQVSDWLYLSGPAGTGKTHLALS
CCCCCCEEEECCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHH
LCAAAEQAGRTPAYLPLQAAAGRLRDALEALEGRSLVALDGVESIAGQRDDEVALFDFHN
HHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHCCCCEEEECCHHHHCCCCCCCEEEEECCC
RARAAGITLLYTARQMPDGLALVLPDLRSRLAQCIRIGLPVLDDAARAAVLRDRAQRRGL
HHHHHCEEEEEEHHHCCCCCEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
ALDEAAIDWLLTHSERELAALVALLDRLDRESLAAKRRITVPFLRRVLEDRGS
CHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA