Click here to switch to the map view.

The map label for this gene is zur [H]

Identifier: 21243573

GI number: 21243573

Start: 3338299

End: 3338805

Strand: Reverse

Name: zur [H]

Synonym: XAC2846

Alternate gene names: 21243573

Gene position: 3338805-3338299 (Counterclockwise)

Preceding gene: 21243574

Following gene: 21243571

Centisome position: 64.51

GC content: 66.67

Gene sequence:

>507_bases
ATGACCAAGCACACCCACGCACCAGACCTCGCCTGCACTGCACCGCATCACCACGTCGACGACGCCAACGGCTTCGTGCG
CGCGGTGGAGCGTGCCTGCAGCGAACGCGGCCTGCGGCTGACGCCGATCCGCGCGAACGTGCTGCGGCTGATCGCCGACG
CCGGCAAGCCGGTCAAGGCCTACGAATTGCTGGACTGGGTGCGCGAAGGCAAGGGCGTCGGCGCCGACGCACCGCCTACG
GTGTATCGCGCGCTGGATTTCCTGATGGCCAACGGCTTCGTGCACAAGCTCGAATCGGTCAATGCGTTCGTCGCCTGCCA
CCACCCCAACAGCGCCCAGCACTCTGTGCCGTTCCTGATCTGCGACCGCTGCCACAGCGCGGTGGAACTGGAAGATCGCG
ACGTCGTGTCGCAACTGGAAGCCCGCGCCAAGGCGCTCGGTTTCCAGCCGCAGGCACAGACGCTGGAAGTGCACGGCCTG
TGCGCGAAATGCGCAGTGGCGGAGTAA

Upstream 100 bases:

>100_bases
GACATTTCGCAAACGGTGTACCTGGCCGGACGCGAGGGTGCCTTGAAACGCATCGATGCGGCACTCATCAAGATTGGAGC
GGCCTGACGCCGGAGCCTGT

Downstream 100 bases:

>100_bases
TCGGCTGCCAGGTCGTGCGTAGAGCACGACCTGTTTCAAGGCGCTCGTGGCGCAATGCCCGGGTGACAGCATGCGTGCGA
TGGCAAGGTGTTGACACGCG

Product: FUR family transcriptional regulator

Products: NA

Alternate protein names: Zinc uptake regulator [H]

Number of amino acids: Translated: 168; Mature: 167

Protein sequence:

>168_residues
MTKHTHAPDLACTAPHHHVDDANGFVRAVERACSERGLRLTPIRANVLRLIADAGKPVKAYELLDWVREGKGVGADAPPT
VYRALDFLMANGFVHKLESVNAFVACHHPNSAQHSVPFLICDRCHSAVELEDRDVVSQLEARAKALGFQPQAQTLEVHGL
CAKCAVAE

Sequences:

>Translated_168_residues
MTKHTHAPDLACTAPHHHVDDANGFVRAVERACSERGLRLTPIRANVLRLIADAGKPVKAYELLDWVREGKGVGADAPPT
VYRALDFLMANGFVHKLESVNAFVACHHPNSAQHSVPFLICDRCHSAVELEDRDVVSQLEARAKALGFQPQAQTLEVHGL
CAKCAVAE
>Mature_167_residues
TKHTHAPDLACTAPHHHVDDANGFVRAVERACSERGLRLTPIRANVLRLIADAGKPVKAYELLDWVREGKGVGADAPPTV
YRALDFLMANGFVHKLESVNAFVACHHPNSAQHSVPFLICDRCHSAVELEDRDVVSQLEARAKALGFQPQAQTLEVHGLC
AKCAVAE

Specific function: Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes (znuACB) [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI87082363, Length=139, Percent_Identity=43.1654676258993, Blast_Score=117, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 18304; Mature: 18173

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
4.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKHTHAPDLACTAPHHHVDDANGFVRAVERACSERGLRLTPIRANVLRLIADAGKPVKA
CCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHCCCCHHH
YELLDWVREGKGVGADAPPTVYRALDFLMANGFVHKLESVNAFVACHHPNSAQHSVPFLI
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCHHH
CDRCHSAVELEDRDVVSQLEARAKALGFQPQAQTLEVHGLCAKCAVAE
HHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TKHTHAPDLACTAPHHHVDDANGFVRAVERACSERGLRLTPIRANVLRLIADAGKPVKA
CCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHCCCCHHH
YELLDWVREGKGVGADAPPTVYRALDFLMANGFVHKLESVNAFVACHHPNSAQHSVPFLI
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCHHH
CDRCHSAVELEDRDVVSQLEARAKALGFQPQAQTLEVHGLCAKCAVAE
HHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 9680209 [H]