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The map label for this gene is trx [H]

Identifier: 21243510

GI number: 21243510

Start: 3263482

End: 3264342

Strand: Direct

Name: trx [H]

Synonym: XAC2783

Alternate gene names: 21243510

Gene position: 3263482-3264342 (Clockwise)

Preceding gene: 21243503

Following gene: 21243511

Centisome position: 63.06

GC content: 66.9

Gene sequence:

>861_bases
ATGTCCGACAAGCCGCATGTATTCGATGCCACCACCGACACCTTCGAGACCGAGGTCCTGCAGAAATCGTTGACGACACC
GGTCCTGGTGGACTTCTGGGCCACCTGGTGCGGCCCCTGCAAGTCGTTGACGCCGATCCTGGAAAAGCTGGCCGGCGAGT
ACAACGGTGCGTTCGAGCTGGGCAAGGTCGATGTGGACAAGGAACAGCAGATCGCTGCGGCGTTCCAGATCCGCTCGGTG
CCGACGGTATTCCTGGTCAAGGGCGGCGAGATCGTCGACGGCTTCCCCGGCGCGATGCCGGAAGGCCAGGTGCGCGAATT
CCTGACCCAGCACGGCGTGCTGCCGGCCGAACCGCAGGTGGCCGAAGAAGACGTGCCGCTGGCGCCGCTCGACCCGCAGG
CGCAGGCCGCGGCGCTGCGTGAGGCGATCGCTGCCGAGCCGGACAAGGACGAACTCAAGCTGGACCTGGCGCTGGCGCTG
CTCAAGACCGGCGACACTGCCGAGGCCGAGCGGTTGATCGACGCCCTGCCCGCCAACCTGGCCACCGACGACCGCGCGGT
GCGCGCCAAGGCGCGGCTGAGCTTTGCCAATGTCCTCAAGGACGCCCCGGACGCCGGCACCTTGCAGTCCGCCGTGGATG
CCAACAGCGCCGACCTGCGCGCGCGTCACCTGCTCGGCGTGCGCCATCTGCTCGACGGCAACGACGAAGCGGCGCTGGAG
CAGTTCCTGGAAATGCTGCGGCAGGACCGCACGTTCGACGACAACCTGCCGCGCCGTAGCCTGATCGATGCGTTTCGTGT
GATCGAGGACGAAGATCTGGTCGGCCGCTATCGTCGCAAGATGTCGGCGCTGGTGTTCTGA

Upstream 100 bases:

>100_bases
CTGACCCGGGCACGTGCGCGGGTCATCGCGGCTAGGCTTGTGTCAGCCGCGTTTGCCACCATTACCTCCCACTGTTGCCG
CACTTAACTTCTGGAAGCCC

Downstream 100 bases:

>100_bases
CAGCCGATGGCGCTTCGGCGCCACACGGACACGTAGGAGCGGACCCGGCCGCGACCAGGGGGTACTCGCCAGTCCCCGAT
AAGGTATTCCCGGGAGCGCG

Product: thioredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MSDKPHVFDATTDTFETEVLQKSLTTPVLVDFWATWCGPCKSLTPILEKLAGEYNGAFELGKVDVDKEQQIAAAFQIRSV
PTVFLVKGGEIVDGFPGAMPEGQVREFLTQHGVLPAEPQVAEEDVPLAPLDPQAQAAALREAIAAEPDKDELKLDLALAL
LKTGDTAEAERLIDALPANLATDDRAVRAKARLSFANVLKDAPDAGTLQSAVDANSADLRARHLLGVRHLLDGNDEAALE
QFLEMLRQDRTFDDNLPRRSLIDAFRVIEDEDLVGRYRRKMSALVF

Sequences:

>Translated_286_residues
MSDKPHVFDATTDTFETEVLQKSLTTPVLVDFWATWCGPCKSLTPILEKLAGEYNGAFELGKVDVDKEQQIAAAFQIRSV
PTVFLVKGGEIVDGFPGAMPEGQVREFLTQHGVLPAEPQVAEEDVPLAPLDPQAQAAALREAIAAEPDKDELKLDLALAL
LKTGDTAEAERLIDALPANLATDDRAVRAKARLSFANVLKDAPDAGTLQSAVDANSADLRARHLLGVRHLLDGNDEAALE
QFLEMLRQDRTFDDNLPRRSLIDAFRVIEDEDLVGRYRRKMSALVF
>Mature_285_residues
SDKPHVFDATTDTFETEVLQKSLTTPVLVDFWATWCGPCKSLTPILEKLAGEYNGAFELGKVDVDKEQQIAAAFQIRSVP
TVFLVKGGEIVDGFPGAMPEGQVREFLTQHGVLPAEPQVAEEDVPLAPLDPQAQAAALREAIAAEPDKDELKLDLALALL
KTGDTAEAERLIDALPANLATDDRAVRAKARLSFANVLKDAPDAGTLQSAVDANSADLRARHLLGVRHLLDGNDEAALEQ
FLEMLRQDRTFDDNLPRRSLIDAFRVIEDEDLVGRYRRKMSALVF

Specific function: Unknown

COG id: COG3118

COG function: function code O; Thioredoxin domain-containing protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI21361403, Length=85, Percent_Identity=44.7058823529412, Blast_Score=84, Evalue=1e-16,
Organism=Escherichia coli, GI87081747, Length=275, Percent_Identity=34.5454545454545, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI87082331, Length=108, Percent_Identity=43.5185185185185, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1788936, Length=104, Percent_Identity=38.4615384615385, Blast_Score=90, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI212646193, Length=109, Percent_Identity=39.4495412844037, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI71980565, Length=84, Percent_Identity=32.1428571428571, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71980562, Length=84, Percent_Identity=32.1428571428571, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17507705, Length=97, Percent_Identity=31.9587628865979, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17509965, Length=86, Percent_Identity=37.2093023255814, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321648, Length=73, Percent_Identity=45.2054794520548, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6323072, Length=90, Percent_Identity=38.8888888888889, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28573567, Length=113, Percent_Identity=34.5132743362832, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24639826, Length=90, Percent_Identity=34.4444444444444, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21358065, Length=98, Percent_Identity=35.7142857142857, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24664269, Length=74, Percent_Identity=40.5405405405405, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI17648013, Length=79, Percent_Identity=41.7721518987342, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24583090, Length=79, Percent_Identity=41.7721518987342, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR013766
- InterPro:   IPR012335
- InterPro:   IPR011990 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: NA

Molecular weight: Translated: 31329; Mature: 31198

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDKPHVFDATTDTFETEVLQKSLTTPVLVDFWATWCGPCKSLTPILEKLAGEYNGAFEL
CCCCCCEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEE
GKVDVDKEQQIAAAFQIRSVPTVFLVKGGEIVDGFPGAMPEGQVREFLTQHGVLPAEPQV
CCCCCCHHHHHHHHHHHHCCCEEEEEECCCEECCCCCCCCCHHHHHHHHHCCCCCCCCCC
AEEDVPLAPLDPQAQAAALREAIAAEPDKDELKLDLALALLKTGDTAEAERLIDALPANL
CCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
ATDDRAVRAKARLSFANVLKDAPDAGTLQSAVDANSADLRARHLLGVRHLLDGNDEAALE
CCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHH
QFLEMLRQDRTFDDNLPRRSLIDAFRVIEDEDLVGRYRRKMSALVF
HHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SDKPHVFDATTDTFETEVLQKSLTTPVLVDFWATWCGPCKSLTPILEKLAGEYNGAFEL
CCCCCEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEE
GKVDVDKEQQIAAAFQIRSVPTVFLVKGGEIVDGFPGAMPEGQVREFLTQHGVLPAEPQV
CCCCCCHHHHHHHHHHHHCCCEEEEEECCCEECCCCCCCCCHHHHHHHHHCCCCCCCCCC
AEEDVPLAPLDPQAQAAALREAIAAEPDKDELKLDLALALLKTGDTAEAERLIDALPANL
CCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
ATDDRAVRAKARLSFANVLKDAPDAGTLQSAVDANSADLRARHLLGVRHLLDGNDEAALE
CCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHH
QFLEMLRQDRTFDDNLPRRSLIDAFRVIEDEDLVGRYRRKMSALVF
HHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]