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The map label for this gene is nuoC

Identifier: 21243430

GI number: 21243430

Start: 3163701

End: 3164453

Strand: Reverse

Name: nuoC

Synonym: XAC2702

Alternate gene names: 21243430

Gene position: 3164453-3163701 (Counterclockwise)

Preceding gene: 21243431

Following gene: 21243429

Centisome position: 61.14

GC content: 65.87

Gene sequence:

>753_bases
ATGGCAGAGCAAGCATCCTCCTTCACTGACCGACTTGCGGCACGTTTCGCCGGTGCGCAGATTGCCGTGGCATTGCCGCG
CGGCGAAGTGACGCTGGAAGTCGCTGCCGCCGATTGGCACGCCACCTGTCTTGCACTGCGTGACGAGCTCGGTTTCGAGC
AGCTCAGCGACCTGTGCGGCGTCGATTACCTCGGCTACGGCAGCGACGAGTGGGATACCGCCGACGTGTCGTCGCAGGGC
TTCAGTCGCGGCGTCGAAGGCAAGGCGGTCGGCCGTTTCGCCTGGGGCGAATTCCCCAGCCAGGAAAGCTCCGCTGGCGC
GCAGCCGCAGCAGCTGCCCAAGCAGCGCTTTGCGGTGGTCGCGCAGCTGATTTCCTACCAGCACAACCAGCGTCTGCGCG
TGCGCTGCTACGCACCGGACGAGCAGGTGCCGGTGGTGGCGTCGGTGACTGATATCTGGCCGGGCGTGAACTGGTTCGAG
CGCGAGGCGTTCGACCTGTTCGGCATCGTGTTCGACGGGCACCCGGACCTGCGCCGCATCCTGACCGACTACGGATTCGT
CGGCCACCCGTTCCGCAAGGACTTCCCGCTGATCGGCAACGTCGAAGTGCGTTACGACGATGAGCGCAAGCGCGTGGTGT
ACGAGCCGGTGACCTCGGTCGAGCCGCGCGTCGGCGTGCCGCGCGTCATTCGCGACGATGCCCGTTATGAGACTGCCGCT
GGTGAAGTGGGCAAGTCGGAGACTGCCAAGTGA

Upstream 100 bases:

>100_bases
GCTGGTCTACGGCATCTTGCAGCTGCAGAAGAAGATCTGGCGTACCCAGACGATCGCGCGCTGACACCCGTCTTCTTCTA
CCGAGAGCAGCCAAGCCCCC

Downstream 100 bases:

>100_bases
GTGAGTTCCGCCAGGCAACCGATGCCTTCGCGAGCAATCCTGTCGAAAGCAAGCAGGAAATCCGCAATTACACGATGAAC
TTCGGCCCGCAGCATCCTGC

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MAEQASSFTDRLAARFAGAQIAVALPRGEVTLEVAAADWHATCLALRDELGFEQLSDLCGVDYLGYGSDEWDTADVSSQG
FSRGVEGKAVGRFAWGEFPSQESSAGAQPQQLPKQRFAVVAQLISYQHNQRLRVRCYAPDEQVPVVASVTDIWPGVNWFE
REAFDLFGIVFDGHPDLRRILTDYGFVGHPFRKDFPLIGNVEVRYDDERKRVVYEPVTSVEPRVGVPRVIRDDARYETAA
GEVGKSETAK

Sequences:

>Translated_250_residues
MAEQASSFTDRLAARFAGAQIAVALPRGEVTLEVAAADWHATCLALRDELGFEQLSDLCGVDYLGYGSDEWDTADVSSQG
FSRGVEGKAVGRFAWGEFPSQESSAGAQPQQLPKQRFAVVAQLISYQHNQRLRVRCYAPDEQVPVVASVTDIWPGVNWFE
REAFDLFGIVFDGHPDLRRILTDYGFVGHPFRKDFPLIGNVEVRYDDERKRVVYEPVTSVEPRVGVPRVIRDDARYETAA
GEVGKSETAK
>Mature_249_residues
AEQASSFTDRLAARFAGAQIAVALPRGEVTLEVAAADWHATCLALRDELGFEQLSDLCGVDYLGYGSDEWDTADVSSQGF
SRGVEGKAVGRFAWGEFPSQESSAGAQPQQLPKQRFAVVAQLISYQHNQRLRVRCYAPDEQVPVVASVTDIWPGVNWFER
EAFDLFGIVFDGHPDLRRILTDYGFVGHPFRKDFPLIGNVEVRYDDERKRVVYEPVTSVEPRVGVPRVIRDDARYETAAG
EVGKSETAK

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758788, Length=104, Percent_Identity=58.6538461538462, Blast_Score=129, Evalue=2e-30,
Organism=Escherichia coli, GI145693162, Length=87, Percent_Identity=47.1264367816092, Blast_Score=82, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71990788, Length=103, Percent_Identity=59.2233009708738, Blast_Score=127, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI32563621, Length=103, Percent_Identity=59.2233009708738, Blast_Score=127, Evalue=7e-30,
Organism=Drosophila melanogaster, GI24656494, Length=104, Percent_Identity=56.7307692307692, Blast_Score=125, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOC_XANAC (Q8PJ42)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_643012.1
- ProteinModelPortal:   Q8PJ42
- SMR:   Q8PJ42
- GeneID:   1156773
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC2702
- NMPDR:   fig|190486.1.peg.2656
- HOGENOM:   HBG727675
- OMA:   VFAPDDD
- ProtClustDB:   PRK06074
- BioCyc:   XAXO190486:XAC2702-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01357
- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581
- TIGRFAMs:   TIGR01961

Pfam domain/function: PF00329 Complex1_30kDa

EC number: =1.6.99.5

Molecular weight: Translated: 27789; Mature: 27658

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEQASSFTDRLAARFAGAQIAVALPRGEVTLEVAAADWHATCLALRDELGFEQLSDLCG
CCCCHHHHHHHHHHHHCCCEEEEEECCCCEEEEEECCCHHHHHHHHHHHCCHHHHHHHHC
VDYLGYGSDEWDTADVSSQGFSRGVEGKAVGRFAWGEFPSQESSAGAQPQQLPKQRFAVV
CCCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
AQLISYQHNQRLRVRCYAPDEQVPVVASVTDIWPGVNWFEREAFDLFGIVFDGHPDLRRI
HHHHHHCCCCEEEEEEECCCCCCCEEEEHHHHCCCCCHHHHHHHHEEEEEECCCHHHHHH
LTDYGFVGHPFRKDFPLIGNVEVRYDDERKRVVYEPVTSVEPRVGVPRVIRDDARYETAA
HHHCCCCCCCCCCCCCEECCEEEEECCCCCEEEECCCCCCCCCCCCCHHHHCCCHHHHHH
GEVGKSETAK
CCCCCCCCCC
>Mature Secondary Structure 
AEQASSFTDRLAARFAGAQIAVALPRGEVTLEVAAADWHATCLALRDELGFEQLSDLCG
CCCHHHHHHHHHHHHCCCEEEEEECCCCEEEEEECCCHHHHHHHHHHHCCHHHHHHHHC
VDYLGYGSDEWDTADVSSQGFSRGVEGKAVGRFAWGEFPSQESSAGAQPQQLPKQRFAVV
CCCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
AQLISYQHNQRLRVRCYAPDEQVPVVASVTDIWPGVNWFEREAFDLFGIVFDGHPDLRRI
HHHHHHCCCCEEEEEEECCCCCCCEEEEHHHHCCCCCHHHHHHHHEEEEEECCCHHHHHH
LTDYGFVGHPFRKDFPLIGNVEVRYDDERKRVVYEPVTSVEPRVGVPRVIRDDARYETAA
HHHCCCCCCCCCCCCCEECCEEEEECCCCCEEEECCCCCCCCCCCCCHHHHCCCHHHHHH
GEVGKSETAK
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12024217