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The map label for this gene is virB11 [H]

Identifier: 21243349

GI number: 21243349

Start: 3083345

End: 3084385

Strand: Reverse

Name: virB11 [H]

Synonym: XAC2618

Alternate gene names: 21243349

Gene position: 3084385-3083345 (Counterclockwise)

Preceding gene: 21243350

Following gene: 21243348

Centisome position: 59.6

GC content: 56.39

Gene sequence:

>1041_bases
ATGACGATCGATGACTCCCCGACAGCGCGTATTTCCAATGACTTTCTGGATTACCAGTACTCCGTGCTGGGAATTCTGGA
CTATCTGAATTCGCCTGACGTGACCGAAATTTGCATCAATCGTCCTGGTGAGCTGTACCTGGAGACGATCCATGGATGGC
AGCGAGTCGACGTGCCATCCCTCACCTACGACCGCGCTCGGCAGTTCTGTACGGCGGTCGTCAATGAGAGCAACACCGGG
CAACGCATCACCGATGCCGACCCTGTCGTATCGCTAACGTTTCCGACCGGGCAACGTGCGCAGTTCGTGATGCCTCCTGC
CTGCGATGCGGGCAAGGTGTCCATCACGATCCGACTTCCTTCGAAGCACACAAAGTCGCTTGAGCAGTACAAGCACGACG
GTTTCTTCGACGAAGTGCTTGAGCAATCGGCGGATGTCAGCGATCACGACCAGGAACTGCTTGAGCTGCGCCGCAAGCGC
GATTACGCAGAGTTTTTCAAGAAGTGCGTGCTTTACAAGAAAAATGTCGTTGTTGCCGGGGCGACAGGTAGCGGCAAAAC
GACCTTCATGAAGGCGCTGGTCAACCACATTCCGAACGAAGAGCGCCTGGTGACGATTGAGGACGCCAGGGAGTTATTCA
TTAGTCAGCCGAACGCTGTGCACCTGCTTTATTCCAAGGGCGGTCAAAGCGCCAGCAACGTGACTGCTAAGAGCTGCATG
GAGGCCTGCCTGCGTATGAAGCCAGACCGCATCATCCTTGCCGAGTTGCGCGGCGATGAGTCGTTCTACTTCATTCGTAA
CTGCGCGTCGGGCCATCCTGGCTCCATCACCAGTTGCCATGCCGGAAGTGTTGAGCAGACCTGGGACCAGCTTGCGTTGA
TGGTGAAGGCCTCCAATGAGGGCTCCGGTCTGGAGTTCGAGGTGATCAAACGTCTGTTGAGAATGACCATCGACATCGTG
GTTCACATCAAGGCGCACGCTGGACGGCGCTTCATCACGGGTATCGATTTCGATCCTCTTCGCACCCTGCGCGGCGGCTA
G

Upstream 100 bases:

>100_bases
CTGCCACACTGACGATCAACCAAGGAACGGTGTTGAACGTCTACGTTGCCAAGGACGTCGATTTCTCGGCTGTCCTGCCG
AAGTGAATGAAATGGTTGCC

Downstream 100 bases:

>100_bases
GGCATCGAGTTCGTCGCTGATTTTGATCTGGTTTTGGAAGGAGTACTGACATGTTGCCTGGCATGGAACTGATGGGGTGC
ACTGGACTGGCCGTCCCCGG

Product: VirB11 protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MTIDDSPTARISNDFLDYQYSVLGILDYLNSPDVTEICINRPGELYLETIHGWQRVDVPSLTYDRARQFCTAVVNESNTG
QRITDADPVVSLTFPTGQRAQFVMPPACDAGKVSITIRLPSKHTKSLEQYKHDGFFDEVLEQSADVSDHDQELLELRRKR
DYAEFFKKCVLYKKNVVVAGATGSGKTTFMKALVNHIPNEERLVTIEDARELFISQPNAVHLLYSKGGQSASNVTAKSCM
EACLRMKPDRIILAELRGDESFYFIRNCASGHPGSITSCHAGSVEQTWDQLALMVKASNEGSGLEFEVIKRLLRMTIDIV
VHIKAHAGRRFITGIDFDPLRTLRGG

Sequences:

>Translated_346_residues
MTIDDSPTARISNDFLDYQYSVLGILDYLNSPDVTEICINRPGELYLETIHGWQRVDVPSLTYDRARQFCTAVVNESNTG
QRITDADPVVSLTFPTGQRAQFVMPPACDAGKVSITIRLPSKHTKSLEQYKHDGFFDEVLEQSADVSDHDQELLELRRKR
DYAEFFKKCVLYKKNVVVAGATGSGKTTFMKALVNHIPNEERLVTIEDARELFISQPNAVHLLYSKGGQSASNVTAKSCM
EACLRMKPDRIILAELRGDESFYFIRNCASGHPGSITSCHAGSVEQTWDQLALMVKASNEGSGLEFEVIKRLLRMTIDIV
VHIKAHAGRRFITGIDFDPLRTLRGG
>Mature_345_residues
TIDDSPTARISNDFLDYQYSVLGILDYLNSPDVTEICINRPGELYLETIHGWQRVDVPSLTYDRARQFCTAVVNESNTGQ
RITDADPVVSLTFPTGQRAQFVMPPACDAGKVSITIRLPSKHTKSLEQYKHDGFFDEVLEQSADVSDHDQELLELRRKRD
YAEFFKKCVLYKKNVVVAGATGSGKTTFMKALVNHIPNEERLVTIEDARELFISQPNAVHLLYSKGGQSASNVTAKSCME
ACLRMKPDRIILAELRGDESFYFIRNCASGHPGSITSCHAGSVEQTWDQLALMVKASNEGSGLEFEVIKRLLRMTIDIVV
HIKAHAGRRFITGIDFDPLRTLRGG

Specific function: The virB operon is essential for intracellular survival and is not involved in the invasion process. Constitutes a major determinant of virulence in mice. Virb11 is essential for pathogenesis in mice but is not required for intracellular survival [H]

COG id: COG0630

COG function: function code NU; Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP E family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014155
- InterPro:   IPR002078
- InterPro:   IPR001482 [H]

Pfam domain/function: PF00437 GSPII_E [H]

EC number: NA

Molecular weight: Translated: 38709; Mature: 38578

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIDDSPTARISNDFLDYQYSVLGILDYLNSPDVTEICINRPGELYLETIHGWQRVDVPS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCEEHHHHCCCEECCCCC
LTYDRARQFCTAVVNESNTGQRITDADPVVSLTFPTGQRAQFVMPPACDAGKVSITIRLP
CCHHHHHHHHHHHHCCCCCCCEECCCCCEEEEECCCCCCCEEECCCCCCCCEEEEEEECC
SKHTKSLEQYKHDGFFDEVLEQSADVSDHDQELLELRRKRDYAEFFKKCVLYKKNVVVAG
CHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEE
ATGSGKTTFMKALVNHIPNEERLVTIEDARELFISQPNAVHLLYSKGGQSASNVTAKSCM
CCCCCHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHH
EACLRMKPDRIILAELRGDESFYFIRNCASGHPGSITSCHAGSVEQTWDQLALMVKASNE
HHHHHCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHEEEEEEECCC
GSGLEFEVIKRLLRMTIDIVVHIKAHAGRRFITGIDFDPLRTLRGG
CCCCCHHHHHHHHHHHHHHEEEEECCCCCEEEECCCCCHHHHCCCC
>Mature Secondary Structure 
TIDDSPTARISNDFLDYQYSVLGILDYLNSPDVTEICINRPGELYLETIHGWQRVDVPS
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCEEHHHHCCCEECCCCC
LTYDRARQFCTAVVNESNTGQRITDADPVVSLTFPTGQRAQFVMPPACDAGKVSITIRLP
CCHHHHHHHHHHHHCCCCCCCEECCCCCEEEEECCCCCCCEEECCCCCCCCEEEEEEECC
SKHTKSLEQYKHDGFFDEVLEQSADVSDHDQELLELRRKRDYAEFFKKCVLYKKNVVVAG
CHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEE
ATGSGKTTFMKALVNHIPNEERLVTIEDARELFISQPNAVHLLYSKGGQSASNVTAKSCM
CCCCCHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHH
EACLRMKPDRIILAELRGDESFYFIRNCASGHPGSITSCHAGSVEQTWDQLALMVKASNE
HHHHHCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHEEEEEEECCC
GSGLEFEVIKRLLRMTIDIVVHIKAHAGRRFITGIDFDPLRTLRGG
CCCCCHHHHHHHHHHHHHHEEEEECCCCCEEEECCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10940027 [H]