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The map label for this gene is gumM [H]

Identifier: 21243306

GI number: 21243306

Start: 3033392

End: 3034183

Strand: Reverse

Name: gumM [H]

Synonym: XAC2574

Alternate gene names: 21243306

Gene position: 3034183-3033392 (Counterclockwise)

Preceding gene: 21243307

Following gene: 21243305

Centisome position: 58.63

GC content: 65.15

Gene sequence:

>792_bases
ATGCAGGGCCAGCGCGTGGATGTGGAAACAACGGGGATTGCCAGCGGGGTCACGCCGCCGGGTGTGGTGATTCCGTTGGG
CGGCTTTCCGGTGTTGTCCACTACGCAGGAAGCCCTCGCGCTGGATCTATTTCATGCACTGGCCGCCCGCCAGCCGCGGC
GGGTGTTCTTTGCCAATACCAATTTCATCGTGCAGTGCCAGGCGCTGCGGGTGCGCATGCGTGAGCCCAGCGTGCGTATC
GTCAACGACGGGATCGGCCTGGATCTGGCTGCGCGGCTGATCCACGGCCGCCGCTTTGCCGGCAACCTCAATGGCACCGA
CCTGATTCCGTATCTGTGCAGCGAGAGTGCGCAACCGCTGAAGTTCTTTCTGCTGGGCGGCCGTCCGGGCGTGGGCAAGA
CCGCTGCGGCCACGCTGACCGGGACCTTGGGGCAGCAGGTGGTCGGCATGTGCGATGGTTATGGCGAATTTGCGGCGGCG
GGCGAGGGCCTGGCCGAGCGCATCAATCGCTCCGGTGCCGATGTGCTGCTGGTGGCGTTCGGCAACCCGCTGCAGGAGCG
CTGGATCCTGGACCACAGCCATGCGCTGAGCGTGCCGCTGGTGTTCGGGGTGGGCGCGTTGCTCGATTTCTTGTCCGGTA
CCGCCAAGCGTGCGCCCGAGTGGGTGCGACGCCTGCATATGGAATGGATGTATCGGCTGCTCAACGAGCCACGCCGTTTG
CTCAAGCGCTATAGCTGGGATCTGCTGGTGTTCTTCCGCACCTGCCTGCGCGCAGGAAAGCAGCTGCCCTGA

Upstream 100 bases:

>100_bases
GAAGAGTGTCTGCAGCTGGGCGGCAACGGCGATTTCGATCTGGAAAGGCTGCAGGCTGGACTGTTGGCTGCCTTCCCTTA
CGACCTTTGGTGATTCGATG

Downstream 100 bases:

>100_bases
TGCAGGGGGGATGCGTCTGGCCTAGCATGCACGCATGCATCCGACCGCCGCCGCCCTGATCCGCTCGCTGGACCTCGCCC
CGCATCCGGAAGGCGGGCAC

Product: GumM protein

Products: NA

Alternate protein names: N-acetylglucosaminyldiphospho-undecaprenol N-acetyl-beta-D-mannosaminyltransferase; UDP-N-acetylmannosamine transferase [H]

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MQGQRVDVETTGIASGVTPPGVVIPLGGFPVLSTTQEALALDLFHALAARQPRRVFFANTNFIVQCQALRVRMREPSVRI
VNDGIGLDLAARLIHGRRFAGNLNGTDLIPYLCSESAQPLKFFLLGGRPGVGKTAAATLTGTLGQQVVGMCDGYGEFAAA
GEGLAERINRSGADVLLVAFGNPLQERWILDHSHALSVPLVFGVGALLDFLSGTAKRAPEWVRRLHMEWMYRLLNEPRRL
LKRYSWDLLVFFRTCLRAGKQLP

Sequences:

>Translated_263_residues
MQGQRVDVETTGIASGVTPPGVVIPLGGFPVLSTTQEALALDLFHALAARQPRRVFFANTNFIVQCQALRVRMREPSVRI
VNDGIGLDLAARLIHGRRFAGNLNGTDLIPYLCSESAQPLKFFLLGGRPGVGKTAAATLTGTLGQQVVGMCDGYGEFAAA
GEGLAERINRSGADVLLVAFGNPLQERWILDHSHALSVPLVFGVGALLDFLSGTAKRAPEWVRRLHMEWMYRLLNEPRRL
LKRYSWDLLVFFRTCLRAGKQLP
>Mature_263_residues
MQGQRVDVETTGIASGVTPPGVVIPLGGFPVLSTTQEALALDLFHALAARQPRRVFFANTNFIVQCQALRVRMREPSVRI
VNDGIGLDLAARLIHGRRFAGNLNGTDLIPYLCSESAQPLKFFLLGGRPGVGKTAAATLTGTLGQQVVGMCDGYGEFAAA
GEGLAERINRSGADVLLVAFGNPLQERWILDHSHALSVPLVFGVGALLDFLSGTAKRAPEWVRRLHMEWMYRLLNEPRRL
LKRYSWDLLVFFRTCLRAGKQLP

Specific function: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, a key lipid intermediate in the de novo synthesis of teichoic acid (Potential) [H]

COG id: COG1922

COG function: function code M; Teichoic acid biosynthesis proteins

Gene ontology:

Cell location: Secreted, cell wall [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 26 family [H]

Homologues:

Organism=Escherichia coli, GI2367289, Length=159, Percent_Identity=33.9622641509434, Blast_Score=81, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004629 [H]

Pfam domain/function: PF03808 Glyco_tran_WecB [H]

EC number: =2.4.1.187 [H]

Molecular weight: Translated: 28791; Mature: 28791

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQGQRVDVETTGIASGVTPPGVVIPLGGFPVLSTTQEALALDLFHALAARQPRRVFFANT
CCCCEECEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECC
NFIVQCQALRVRMREPSVRIVNDGIGLDLAARLIHGRRFAGNLNGTDLIPYLCSESAQPL
CEEEEEHHHHHHHCCCCEEEEECCCCHHHHHHHHHCHHHCCCCCCCHHHHHHHCCCCCCE
KFFLLGGRPGVGKTAAATLTGTLGQQVVGMCDGYGEFAAAGEGLAERINRSGADVLLVAF
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEC
GNPLQERWILDHSHALSVPLVFGVGALLDFLSGTAKRAPEWVRRLHMEWMYRLLNEPRRL
CCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHH
LKRYSWDLLVFFRTCLRAGKQLP
HHHHCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MQGQRVDVETTGIASGVTPPGVVIPLGGFPVLSTTQEALALDLFHALAARQPRRVFFANT
CCCCEECEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECC
NFIVQCQALRVRMREPSVRIVNDGIGLDLAARLIHGRRFAGNLNGTDLIPYLCSESAQPL
CEEEEEHHHHHHHCCCCEEEEECCCCHHHHHHHHHCHHHCCCCCCCHHHHHHHCCCCCCE
KFFLLGGRPGVGKTAAATLTGTLGQQVVGMCDGYGEFAAAGEGLAERINRSGADVLLVAF
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEC
GNPLQERWILDHSHALSVPLVFGVGALLDFLSGTAKRAPEWVRRLHMEWMYRLLNEPRRL
CCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHH
LKRYSWDLLVFFRTCLRAGKQLP
HHHHCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11882717 [H]