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The map label for this gene is cho [H]

Identifier: 21243291

GI number: 21243291

Start: 3017502

End: 3018356

Strand: Direct

Name: cho [H]

Synonym: XAC2558

Alternate gene names: 21243291

Gene position: 3017502-3018356 (Clockwise)

Preceding gene: 21243290

Following gene: 21243293

Centisome position: 58.3

GC content: 63.86

Gene sequence:

>855_bases
GTGGCCCGCAGTGAACGCGTTCGCCGCGCGCTCGGCGCGGTCGAATACGCCTACCCCGACCATTTGCGCAGCACGCTCGC
GACCTTGCCGACGACTGCCGGGGTGTATCTGTTCCATGGCAAGGACAGCGGACTCCCCTTGTACATCGGCAAGAGCATCA
ACCTGCGGATGCGGGTGATGGATCACTTCCGCACGCCACGCGAAGCCTCGTTATTGCGCCAGACCCGGCGCATCAGCGTA
TTCGAAATGGCCGGCGATCTCGGTGCGCAGCTGCTGGAATCCCAGCTCATCAAATCGATGCGCCCGCTGTACAACCAGAA
GCTGCGTCGCGTACCGCGTCAGTTTTCGATCCGCCTGTATTGCGGCGAGGTGTCCATCGTGCATTCGGCCGAGCGCGATC
CGGCGGTAACACCATGGCTGTATGGGCTCTATTCCAGCCCACGCGCCGCCAAGGAGGCGTTGCGGCGGCTGGCCGATCGC
GACCGCCTTTGCTACGGGCTGCTCGGCCTGGAACGCGCCACCGATGGTCGCCCGTGTTTCCGCGCCATGTTGGAACGCTG
TGCCGGTGCCTGCCATGGCGCCGAGTCGCTGGGCGACCACGAGACGCGTCTACGCGCTGCCCTCCAGCACCTGGAACAGG
TCGTATGGCCGTTTCCTGGCGCGGTCGCACTCATGGAAGAAGGTAAGCAGTTGCGCCAGTTTCACGTGCTGCGCGACTGG
CACTATCTGGGCAGCGCCACCTCGCTGGCCACTGCCCGCAAACTGCAGTCCACACCCGGCGACTTCGATCGCGATTGCTA
CCGGATTTTGCGCAAGGGCCTGCAAACGCATCTGCACAACGTGGTGTTGCTATAA

Upstream 100 bases:

>100_bases
TTCCAGGCATTCCCACATGCCACCGTGCATACAGCAGCGCCGCGCCATGTGGGTGGTTGCGCACGAGTCGATACGCTGAC
GCAGCAGACCAAGGTCCGCC

Downstream 100 bases:

>100_bases
GCGCGACATGAGTGGGCGCGCCCACTTCGGCACTCGCAGTACGCACCGAGTTCATGCGAGGCATCGCGCGACTTGCCGCC
GGTCTTCCCTGTTCCCCGCC

Product: nucleotide excision repair endonuclease

Products: NA

Alternate protein names: Endonuclease cho; UvrC homolog protein [H]

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MARSERVRRALGAVEYAYPDHLRSTLATLPTTAGVYLFHGKDSGLPLYIGKSINLRMRVMDHFRTPREASLLRQTRRISV
FEMAGDLGAQLLESQLIKSMRPLYNQKLRRVPRQFSIRLYCGEVSIVHSAERDPAVTPWLYGLYSSPRAAKEALRRLADR
DRLCYGLLGLERATDGRPCFRAMLERCAGACHGAESLGDHETRLRAALQHLEQVVWPFPGAVALMEEGKQLRQFHVLRDW
HYLGSATSLATARKLQSTPGDFDRDCYRILRKGLQTHLHNVVLL

Sequences:

>Translated_284_residues
MARSERVRRALGAVEYAYPDHLRSTLATLPTTAGVYLFHGKDSGLPLYIGKSINLRMRVMDHFRTPREASLLRQTRRISV
FEMAGDLGAQLLESQLIKSMRPLYNQKLRRVPRQFSIRLYCGEVSIVHSAERDPAVTPWLYGLYSSPRAAKEALRRLADR
DRLCYGLLGLERATDGRPCFRAMLERCAGACHGAESLGDHETRLRAALQHLEQVVWPFPGAVALMEEGKQLRQFHVLRDW
HYLGSATSLATARKLQSTPGDFDRDCYRILRKGLQTHLHNVVLL
>Mature_283_residues
ARSERVRRALGAVEYAYPDHLRSTLATLPTTAGVYLFHGKDSGLPLYIGKSINLRMRVMDHFRTPREASLLRQTRRISVF
EMAGDLGAQLLESQLIKSMRPLYNQKLRRVPRQFSIRLYCGEVSIVHSAERDPAVTPWLYGLYSSPRAAKEALRRLADRD
RLCYGLLGLERATDGRPCFRAMLERCAGACHGAESLGDHETRLRAALQHLEQVVWPFPGAVALMEEGKQLRQFHVLRDWH
YLGSATSLATARKLQSTPGDFDRDCYRILRKGLQTHLHNVVLL

Specific function: Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than uvrC. Not able to incise the 5' site of a lesion. When a lesion remains because uvrC is not able to induce the 3' incision, cho

COG id: COG0322

COG function: function code L; Nuclease subunit of the excinuclease complex

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 uvrC C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1788037, Length=273, Percent_Identity=49.0842490842491, Blast_Score=268, Evalue=3e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000305 [H]

Pfam domain/function: PF01541 GIY-YIG [H]

EC number: NA

Molecular weight: Translated: 32308; Mature: 32177

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: PS50164 UVRC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARSERVRRALGAVEYAYPDHLRSTLATLPTTAGVYLFHGKDSGLPLYIGKSINLRMRVM
CCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEECCCCCCCEEECCCCCHHHHHH
DHFRTPREASLLRQTRRISVFEMAGDLGAQLLESQLIKSMRPLYNQKLRRVPRQFSIRLY
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHEEEEE
CGEVSIVHSAERDPAVTPWLYGLYSSPRAAKEALRRLADRDRLCYGLLGLERATDGRPCF
ECCEEEEECCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
RAMLERCAGACHGAESLGDHETRLRAALQHLEQVVWPFPGAVALMEEGKQLRQFHVLRDW
HHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
HYLGSATSLATARKLQSTPGDFDRDCYRILRKGLQTHLHNVVLL
HHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ARSERVRRALGAVEYAYPDHLRSTLATLPTTAGVYLFHGKDSGLPLYIGKSINLRMRVM
CHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEECCCCCCCEEECCCCCHHHHHH
DHFRTPREASLLRQTRRISVFEMAGDLGAQLLESQLIKSMRPLYNQKLRRVPRQFSIRLY
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHEEEEE
CGEVSIVHSAERDPAVTPWLYGLYSSPRAAKEALRRLADRDRLCYGLLGLERATDGRPCF
ECCEEEEECCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
RAMLERCAGACHGAESLGDHETRLRAALQHLEQVVWPFPGAVALMEEGKQLRQFHVLRDW
HHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
HYLGSATSLATARKLQSTPGDFDRDCYRILRKGLQTHLHNVVLL
HHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]