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The map label for this gene is pepQ [H]

Identifier: 21243278

GI number: 21243278

Start: 3001698

End: 3002897

Strand: Reverse

Name: pepQ [H]

Synonym: XAC2545

Alternate gene names: 21243278

Gene position: 3002897-3001698 (Counterclockwise)

Preceding gene: 21243279

Following gene: 21243277

Centisome position: 58.02

GC content: 66.5

Gene sequence:

>1200_bases
ATGAAGCGACAGATCGGCGGGCTGTCGCTGGAGCAAGCGCGTGCGCAACTCGCGCCGTGGACACAACGCGCCGCGCCGAT
CGCCGCGGACGAATACGAGCGCCGCATCGAGCGTGCACGCAGCCTCATGCGCGGGCATGGCGTGGATGCGCTGTTGATCG
GCGCCGGCACGTCGCTGCGCTATTTCACCGGCGTGCCGTGGGGGGCGAGCGAGCGTCTGGTGGCACTGCTGCTGACGCTG
GATGGCGATCCGGTGTTGATCTGCCCCGTGTTCGAGGAAGGCTCGCTGGATGCGGTACTGAAGATCCCGGCGACCAAATA
CCTGTGGGAAGAGCACGACGACCCGTACGCACTGGTGGTACAGGCCATGGATGAGCGCCATGCGCACGCCCTGGCGCTGG
ACCCCGGCATCGCGTTCGCCGTGCACACCGGTCTGCGTGCGCATCTGGGCAAGGCGATTCGTGATGCCGGCGCGATCATC
GATGGCTGCCGCATGTGCAAGTCGCCAGCCGAGCTGGCATTGATGCAGCAGGCTTGCGATATGACCTTGCTGGTACAGCG
GCTGGCGGCCGGTATCGCGCACGACGGGATCGGGACCGATGAACTGGTGCGTTTCATCGATGAGGCGCATCGCGCGCTGG
GCGCCGACAACGGATCGACCTTCTGTATCGTGCAGTACGGTCACGCCACTGCGTTTCCGCATGGCATCCCGGGTGTGCAG
CACCTGCGCGAAGGTGAACTGGTGTTGATCGACACCGGCTGCACCGTGCAGGGCTACCACTCCGACATCACCCGCACCTG
GATCTATGGTGCGGCCAACGACGCGCAGCAGCGCATCTGGGACCTGGAGCAGGCCGCGCAGGCGGCGGCATTCGCAGCGA
TCCGCCCGGGCGTGGCATGCGAAGCGGTGGATCAGGCTGCGCGCAAGGTGCTGGAAGCAGCCGGGCTCGGGCCCGACTAT
CGGCTGCCCGGGTTGCCGCATCGCACCGGTCACGGTTGCGGCCTGGCGATTCACGAGGCGCCTTACCTGGTGCGCGGCAA
TGCGCTGGCGTTGCAGCCGGGCATGTGTGCCAGCAACGAGCCGATGATCGTGGTGCCGGAGCAGTTCGGCGTGCGCCTGG
AAGACCATTTCTACGTGACCGACGATGGTGCGCAGTGGTTCACGCCGCCGTCGGTGGCGATCGATCAACCGTTTGCGTGA

Upstream 100 bases:

>100_bases
CCGATGCACTGCTGCCCGCCGAACTGCGCCAGCGCAATCCGGGCGGCGTGGCACGTCTGGTCGACGGGCAATGGAGCACG
GCCGATCTTGGAGCCGGCGC

Downstream 100 bases:

>100_bases
GTCTGCGAAGGTTCACGCGCGCGTAGGAGCGCACCCGGGCGCGACGGGCATTCCCGAGTGAAGCCATTCGCGCTCAGGCG
CGCTCCTACCGCTGTCCTTG

Product: proline dipeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MKRQIGGLSLEQARAQLAPWTQRAAPIAADEYERRIERARSLMRGHGVDALLIGAGTSLRYFTGVPWGASERLVALLLTL
DGDPVLICPVFEEGSLDAVLKIPATKYLWEEHDDPYALVVQAMDERHAHALALDPGIAFAVHTGLRAHLGKAIRDAGAII
DGCRMCKSPAELALMQQACDMTLLVQRLAAGIAHDGIGTDELVRFIDEAHRALGADNGSTFCIVQYGHATAFPHGIPGVQ
HLREGELVLIDTGCTVQGYHSDITRTWIYGAANDAQQRIWDLEQAAQAAAFAAIRPGVACEAVDQAARKVLEAAGLGPDY
RLPGLPHRTGHGCGLAIHEAPYLVRGNALALQPGMCASNEPMIVVPEQFGVRLEDHFYVTDDGAQWFTPPSVAIDQPFA

Sequences:

>Translated_399_residues
MKRQIGGLSLEQARAQLAPWTQRAAPIAADEYERRIERARSLMRGHGVDALLIGAGTSLRYFTGVPWGASERLVALLLTL
DGDPVLICPVFEEGSLDAVLKIPATKYLWEEHDDPYALVVQAMDERHAHALALDPGIAFAVHTGLRAHLGKAIRDAGAII
DGCRMCKSPAELALMQQACDMTLLVQRLAAGIAHDGIGTDELVRFIDEAHRALGADNGSTFCIVQYGHATAFPHGIPGVQ
HLREGELVLIDTGCTVQGYHSDITRTWIYGAANDAQQRIWDLEQAAQAAAFAAIRPGVACEAVDQAARKVLEAAGLGPDY
RLPGLPHRTGHGCGLAIHEAPYLVRGNALALQPGMCASNEPMIVVPEQFGVRLEDHFYVTDDGAQWFTPPSVAIDQPFA
>Mature_399_residues
MKRQIGGLSLEQARAQLAPWTQRAAPIAADEYERRIERARSLMRGHGVDALLIGAGTSLRYFTGVPWGASERLVALLLTL
DGDPVLICPVFEEGSLDAVLKIPATKYLWEEHDDPYALVVQAMDERHAHALALDPGIAFAVHTGLRAHLGKAIRDAGAII
DGCRMCKSPAELALMQQACDMTLLVQRLAAGIAHDGIGTDELVRFIDEAHRALGADNGSTFCIVQYGHATAFPHGIPGVQ
HLREGELVLIDTGCTVQGYHSDITRTWIYGAANDAQQRIWDLEQAAQAAAFAAIRPGVACEAVDQAARKVLEAAGLGPDY
RLPGLPHRTGHGCGLAIHEAPYLVRGNALALQPGMCASNEPMIVVPEQFGVRLEDHFYVTDDGAQWFTPPSVAIDQPFA

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Escherichia coli, GI1788728, Length=230, Percent_Identity=35.6521739130435, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1789275, Length=258, Percent_Identity=27.1317829457364, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1786364, Length=252, Percent_Identity=23.4126984126984, Blast_Score=72, Evalue=8e-14,
Organism=Drosophila melanogaster, GI19920384, Length=410, Percent_Identity=25.609756097561, Blast_Score=82, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 43021; Mature: 43021

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRQIGGLSLEQARAQLAPWTQRAAPIAADEYERRIERARSLMRGHGVDALLIGAGTSLR
CCCCCCCCCHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEE
YFTGVPWGASERLVALLLTLDGDPVLICPVFEEGSLDAVLKIPATKYLWEEHDDPYALVV
EEECCCCCCCCCEEEEEEEECCCCEEEEEECCCCCCCEEEECCCHHHHHHCCCCCCEEHH
QAMDERHAHALALDPGIAFAVHTGLRAHLGKAIRDAGAIIDGCRMCKSPAELALMQQACD
HHHHCCCCEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
MTLLVQRLAAGIAHDGIGTDELVRFIDEAHRALGADNGSTFCIVQYGHATAFPHGIPGVQ
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCHH
HLREGELVLIDTGCTVQGYHSDITRTWIYGAANDAQQRIWDLEQAAQAAAFAAIRPGVAC
HHCCCCEEEEECCCEEECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHH
EAVDQAARKVLEAAGLGPDYRLPGLPHRTGHGCGLAIHEAPYLVRGNALALQPGMCASNE
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCEEEECCEEEECCCCCCCCC
PMIVVPEQFGVRLEDHFYVTDDGAQWFTPPSVAIDQPFA
CEEEECHHHCCEEECEEEEECCCCCEECCCCCCCCCCCC
>Mature Secondary Structure
MKRQIGGLSLEQARAQLAPWTQRAAPIAADEYERRIERARSLMRGHGVDALLIGAGTSLR
CCCCCCCCCHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEE
YFTGVPWGASERLVALLLTLDGDPVLICPVFEEGSLDAVLKIPATKYLWEEHDDPYALVV
EEECCCCCCCCCEEEEEEEECCCCEEEEEECCCCCCCEEEECCCHHHHHHCCCCCCEEHH
QAMDERHAHALALDPGIAFAVHTGLRAHLGKAIRDAGAIIDGCRMCKSPAELALMQQACD
HHHHCCCCEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
MTLLVQRLAAGIAHDGIGTDELVRFIDEAHRALGADNGSTFCIVQYGHATAFPHGIPGVQ
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCHH
HLREGELVLIDTGCTVQGYHSDITRTWIYGAANDAQQRIWDLEQAAQAAAFAAIRPGVAC
HHCCCCEEEEECCCEEECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHH
EAVDQAARKVLEAAGLGPDYRLPGLPHRTGHGCGLAIHEAPYLVRGNALALQPGMCASNE
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCEEEECCEEEECCCCCCCCC
PMIVVPEQFGVRLEDHFYVTDDGAQWFTPPSVAIDQPFA
CEEEECHHHCCEEECEEEEECCCCCEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]