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The map label for this gene is ygjG [C]

Identifier: 21243222

GI number: 21243222

Start: 2899970

End: 2901322

Strand: Direct

Name: ygjG [C]

Synonym: XAC2489

Alternate gene names: 21243222

Gene position: 2899970-2901322 (Clockwise)

Preceding gene: 21243216

Following gene: 21243223

Centisome position: 56.03

GC content: 66.89

Gene sequence:

>1353_bases
ATGCCCGACCACCTTCCCAGCGATGCCGCCGATGCGCTGCAGGCACCGACGCAGCTGGATGCCTTCTGGATGCCGTTCAC
CGCCAATCGCCAGTTCAAGGCACGGCCTCGCCTGCTGGCCTCGGCGCAGGGCATGTATTACCGCGATGTCCAAGGACGCC
AGATTCTGGACGGCACGGCAGGCCTGTGGTGCTGCAATGCAGGACATAGCCGCGAGCGCATCGTGGCAGCCATCCGCGAC
CAGGCCGGCACGCTGGATTTCGCGCCGACCTTCCAGATGGGCTCGCCGCTGCCCTTCGTGCTGGCGCAGCGGTTGGCCGC
AATCGCCCCGCCGGGCCTGGGCCATGTGTTCTTCACCAACTCCGGCTCGGAAGCGGTGGATAGCGCGATGAAGATCGTGC
TTGCCTACCACCGGCTGCGCGGCGAAGGCCAGCGCACCCGCTTCATCGGTCGCGAGAAGGCCTACCACGGGGTCGGCTTC
GGCGGCATGTCGATCGGCGGGCTGCCCAACAACCGCAAGTGGTTCGGCCCATTGCTGGCCGGCACCGACCATTTGCCGCA
TACGCTGGATCTGCAGCACAACGCCTACGCGCGCGGGCTGCCTGTGCATGGCGCGGAACTGGCCGACGATCTGGAACGGC
TGATCACCTTGCACGATGCGTCCACCATCGCGGCGGTTTTCGTCGAACCGGTGTCCGGTTCGGCCGGTGTGATCCTGCCG
CCGGAGGGCTACCTGCAGCGGTTGCGCGCCATCTGCGACCGCCACGGCATTGTATTGGTGTTCGACGAGGTGATCACCGG
CTTCGGCCGCGTGGGCGACGCCTTCGCCGCACAGCGCTTCGGCGTCATCCCGGACATCATCACCGCCGCCAAGGGCCTGA
CCAGCGGCACCGTGCCGATGGGCGCGGTGCTGGTGGCCGATGCGATCCACGATGCCTTCATGCACGGGCCGCAAAACGCG
ATCGAGCTCTTTCACGGCTACACCTATTCCGGCCATCCGCTGGCCTGTGCAGCGGCGATCGCCACGCTGGACACCTATGC
CGAGGAAGAGCTGTTCACGCGCGCGATCACGCTTGGCCCGCAGTGGGAAGACGCATTGCACGGCCTGCGCGGCTCGCCGC
ATGTGATCGACATCCGCAACATCGGCCTGATCGGCGCGATCGAACTGGCACCACGCGACGGCGCCCCGGGCGCGCGCGGT
TACGACGTCTTCGAGCGCTGTTTCCACGAGGGCGGCCTGCTGGTGCGCGTCACCGGCGATGTCATCGCACTGTCACCGCC
GCTGATCGTCACCCCGGAGCAGATCGGGCAGATGGTGGAGACGCTAGGCAAGATTCTTCGCCAGGTGGACTAA

Upstream 100 bases:

>100_bases
TGCACGACGCGCCTGCTTGCTGTGCGTCTGCGGGCGTCTCAGGTGACGGCCCAGGCGCCAGCTGCGTACAGTCGGGCGAT
CCCGAACGACGGAGCCTGCC

Downstream 100 bases:

>100_bases
GCCCGGCTGGCCACGGGCGATGACCACAAACTGCGCTGGCGACGGGCGCCCGCGTGTCACGCATGCAGGCACCCGTCAAG
CGCGCAAAGCCGGGGCAGGC

Product: beta alanine--pyruvate transaminase

Products: NA

Alternate protein names: Omega-APT; Beta-alanine--pyruvate aminotransferase [H]

Number of amino acids: Translated: 450; Mature: 449

Protein sequence:

>450_residues
MPDHLPSDAADALQAPTQLDAFWMPFTANRQFKARPRLLASAQGMYYRDVQGRQILDGTAGLWCCNAGHSRERIVAAIRD
QAGTLDFAPTFQMGSPLPFVLAQRLAAIAPPGLGHVFFTNSGSEAVDSAMKIVLAYHRLRGEGQRTRFIGREKAYHGVGF
GGMSIGGLPNNRKWFGPLLAGTDHLPHTLDLQHNAYARGLPVHGAELADDLERLITLHDASTIAAVFVEPVSGSAGVILP
PEGYLQRLRAICDRHGIVLVFDEVITGFGRVGDAFAAQRFGVIPDIITAAKGLTSGTVPMGAVLVADAIHDAFMHGPQNA
IELFHGYTYSGHPLACAAAIATLDTYAEEELFTRAITLGPQWEDALHGLRGSPHVIDIRNIGLIGAIELAPRDGAPGARG
YDVFERCFHEGGLLVRVTGDVIALSPPLIVTPEQIGQMVETLGKILRQVD

Sequences:

>Translated_450_residues
MPDHLPSDAADALQAPTQLDAFWMPFTANRQFKARPRLLASAQGMYYRDVQGRQILDGTAGLWCCNAGHSRERIVAAIRD
QAGTLDFAPTFQMGSPLPFVLAQRLAAIAPPGLGHVFFTNSGSEAVDSAMKIVLAYHRLRGEGQRTRFIGREKAYHGVGF
GGMSIGGLPNNRKWFGPLLAGTDHLPHTLDLQHNAYARGLPVHGAELADDLERLITLHDASTIAAVFVEPVSGSAGVILP
PEGYLQRLRAICDRHGIVLVFDEVITGFGRVGDAFAAQRFGVIPDIITAAKGLTSGTVPMGAVLVADAIHDAFMHGPQNA
IELFHGYTYSGHPLACAAAIATLDTYAEEELFTRAITLGPQWEDALHGLRGSPHVIDIRNIGLIGAIELAPRDGAPGARG
YDVFERCFHEGGLLVRVTGDVIALSPPLIVTPEQIGQMVETLGKILRQVD
>Mature_449_residues
PDHLPSDAADALQAPTQLDAFWMPFTANRQFKARPRLLASAQGMYYRDVQGRQILDGTAGLWCCNAGHSRERIVAAIRDQ
AGTLDFAPTFQMGSPLPFVLAQRLAAIAPPGLGHVFFTNSGSEAVDSAMKIVLAYHRLRGEGQRTRFIGREKAYHGVGFG
GMSIGGLPNNRKWFGPLLAGTDHLPHTLDLQHNAYARGLPVHGAELADDLERLITLHDASTIAAVFVEPVSGSAGVILPP
EGYLQRLRAICDRHGIVLVFDEVITGFGRVGDAFAAQRFGVIPDIITAAKGLTSGTVPMGAVLVADAIHDAFMHGPQNAI
ELFHGYTYSGHPLACAAAIATLDTYAEEELFTRAITLGPQWEDALHGLRGSPHVIDIRNIGLIGAIELAPRDGAPGARGY
DVFERCFHEGGLLVRVTGDVIALSPPLIVTPEQIGQMVETLGKILRQVD

Specific function: Catalyzes transamination between a variety of omega- amino acids, mono and diamines, and pyruvate. Plays a pivotal role in the metabolism of the omega amino acids [H]

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=438, Percent_Identity=29.4520547945205, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI284507298, Length=332, Percent_Identity=30.7228915662651, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI37574042, Length=428, Percent_Identity=29.4392523364486, Blast_Score=135, Evalue=9e-32,
Organism=Homo sapiens, GI226442705, Length=428, Percent_Identity=29.4392523364486, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI13994255, Length=441, Percent_Identity=27.891156462585, Blast_Score=130, Evalue=4e-30,
Organism=Homo sapiens, GI226442709, Length=392, Percent_Identity=29.5918367346939, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI24119277, Length=437, Percent_Identity=26.5446224256293, Blast_Score=122, Evalue=6e-28,
Organism=Escherichia coli, GI145693181, Length=402, Percent_Identity=32.5870646766169, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1786991, Length=435, Percent_Identity=31.264367816092, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1789759, Length=432, Percent_Identity=30.5555555555556, Blast_Score=161, Evalue=8e-41,
Organism=Escherichia coli, GI1789016, Length=414, Percent_Identity=31.1594202898551, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1787560, Length=438, Percent_Identity=30.8219178082192, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1788044, Length=402, Percent_Identity=28.6069651741293, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1786349, Length=335, Percent_Identity=28.955223880597, Blast_Score=95, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI25144271, Length=422, Percent_Identity=27.9620853080569, Blast_Score=157, Evalue=9e-39,
Organism=Caenorhabditis elegans, GI32564660, Length=439, Percent_Identity=27.5626423690205, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI25144274, Length=298, Percent_Identity=29.8657718120805, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI71992977, Length=445, Percent_Identity=26.7415730337079, Blast_Score=128, Evalue=8e-30,
Organism=Saccharomyces cerevisiae, GI6323470, Length=437, Percent_Identity=27.6887871853547, Blast_Score=169, Evalue=9e-43,
Organism=Saccharomyces cerevisiae, GI6324386, Length=443, Percent_Identity=26.410835214447, Blast_Score=141, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6324432, Length=430, Percent_Identity=26.046511627907, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21357415, Length=417, Percent_Identity=26.8585131894484, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI161085790, Length=441, Percent_Identity=28.7981859410431, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI28574759, Length=429, Percent_Identity=29.1375291375291, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI21356575, Length=434, Percent_Identity=28.110599078341, Blast_Score=115, Evalue=8e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.18 [H]

Molecular weight: Translated: 48332; Mature: 48201

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDHLPSDAADALQAPTQLDAFWMPFTANRQFKARPRLLASAQGMYYRDVQGRQILDGTA
CCCCCCCCHHHHHCCCCCCCEEECCCCCCCCCCCCCHHHHHCCCCEEECCCCCEEECCCC
GLWCCNAGHSRERIVAAIRDQAGTLDFAPTFQMGSPLPFVLAQRLAAIAPPGLGHVFFTN
CEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEC
SGSEAVDSAMKIVLAYHRLRGEGQRTRFIGREKAYHGVGFGGMSIGGLPNNRKWFGPLLA
CCHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHCCCCCCCCCCEECCCCCCCCCCCHHHC
GTDHLPHTLDLQHNAYARGLPVHGAELADDLERLITLHDASTIAAVFVEPVSGSAGVILP
CCCCCCCEEECCCCCHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCEEEC
PEGYLQRLRAICDRHGIVLVFDEVITGFGRVGDAFAAQRFGVIPDIITAAKGLTSGTVPM
CHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCH
GAVLVADAIHDAFMHGPQNAIELFHGYTYSGHPLACAAAIATLDTYAEEELFTRAITLGP
HHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QWEDALHGLRGSPHVIDIRNIGLIGAIELAPRDGAPGARGYDVFERCFHEGGLLVRVTGD
CHHHHHHCCCCCCCEEEEECCCEEEEEEECCCCCCCCCCCHHHHHHHHHCCCEEEEEECC
VIALSPPLIVTPEQIGQMVETLGKILRQVD
EEEECCCEEECHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PDHLPSDAADALQAPTQLDAFWMPFTANRQFKARPRLLASAQGMYYRDVQGRQILDGTA
CCCCCCCHHHHHCCCCCCCEEECCCCCCCCCCCCCHHHHHCCCCEEECCCCCEEECCCC
GLWCCNAGHSRERIVAAIRDQAGTLDFAPTFQMGSPLPFVLAQRLAAIAPPGLGHVFFTN
CEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEC
SGSEAVDSAMKIVLAYHRLRGEGQRTRFIGREKAYHGVGFGGMSIGGLPNNRKWFGPLLA
CCHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHCCCCCCCCCCEECCCCCCCCCCCHHHC
GTDHLPHTLDLQHNAYARGLPVHGAELADDLERLITLHDASTIAAVFVEPVSGSAGVILP
CCCCCCCEEECCCCCHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCEEEC
PEGYLQRLRAICDRHGIVLVFDEVITGFGRVGDAFAAQRFGVIPDIITAAKGLTSGTVPM
CHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCH
GAVLVADAIHDAFMHGPQNAIELFHGYTYSGHPLACAAAIATLDTYAEEELFTRAITLGP
HHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QWEDALHGLRGSPHVIDIRNIGLIGAIELAPRDGAPGARGYDVFERCFHEGGLLVRVTGD
CHHHHHHCCCCCCCEEEEECCCEEEEEEECCCCCCCCCCCHHHHHHHHHCCCEEEEEECC
VIALSPPLIVTPEQIGQMVETLGKILRQVD
EEEECCCEEECHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1618757; 6822556; 2500426 [H]