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The map label for this gene is wrbA [H]

Identifier: 21242967

GI number: 21242967

Start: 2615050

End: 2616132

Strand: Reverse

Name: wrbA [H]

Synonym: XAC2232

Alternate gene names: 21242967

Gene position: 2616132-2615050 (Counterclockwise)

Preceding gene: 21242968

Following gene: 21242966

Centisome position: 50.55

GC content: 60.66

Gene sequence:

>1083_bases
ATGGCGCAAGAAAAAGCAAAGATCCTCGTTCTGATCCATTCCGAGAACGGAGGAACCTATGAACTGGCCAAGGAAGTTGC
GGCGGGAATCCAAAGCATCGGAGAGGTCGAGTCTGTCATCAAGCAGGTGCGTGCCTCCGACAAGCCTGCTTTGAAAGACA
TCCCTGTCGCCACCACGCAGGAGTTGACGAATTACGACGGCATTGCATTCGGCTCCCCCGTCTACTTCGCCAATCCCAGT
CCTGCCATCGGAGCGTTTCTTGCGGGAACAGTGGACTTGTGGACCCGCCACGCACTCGAAGGCGTGCCCGCAACCGTGTT
CATGTCTGCCGGTAGCGGGGCTGGCAACGAGCTGGCGATTCAATCCTTCAGGAACAGCCTGGCGGCCCACGGCATGGTGC
TGGTTCCCAACGGGATTCGTGGCGCCGAAGCGGTCGACAACACGATTCCACAGGGCAATACCATCCTTGGCGCGACCAGC
CTTGCCGGACTCAAAGGCAGTCCGAGGCCGAGTCCCAGCGAGCGCCAGGTCGCGCGGCTGCAAGGCAGCCATTTCGCGAA
GGTAGCACTCGCACTGAGAGGCGTTCGTCCCCAGCCGACGGCACGCACTGAGGCATCTCGCCGCGTCGATATCAACACTG
CTCTCAGCGAGAAAGGCATCGTTCTTCCGCCGCCACCTGCGCCTGTGGGTAATTACACCCCCTTTGCACGCTCTGGCAAT
CTGGTCTTCATCAATCAGGTGGCATTGAAGGATGGTGCCATCGTGCATGCGGGCAAGGTTGGCGCGGGCGTTAGCGATGA
TCAAGCCAAGGAAGCTACCCGCGTCACCATGCTCAACGTGCTGGCGGTGCTGAAAGATGCCGTGGGTGGCGATCTGAACC
GAGTTCGGCGCACGGTTCAGTTGACCGGCCTGTTCAACACCACCAACGACTATGCCGATCACGCCAAGCTGCTGAATGTG
GCCTCGGACCTAACGGTCGAGGTCTTTGGTGAACGAGGCAAGCATGCCCGGGCCGCAGTGGGCGCCGCCTCGCTGCCAGT
GGCCTCGCCCGTGGAGATCCAAGCGATCTTCGAGGTCGAGTAG

Upstream 100 bases:

>100_bases
GGCTTCATCCTTTATGGCGCGGTTTGGCCGGTCACTTGGACGATCAAATATGAAGCGTTTGATGCTGCTGGTTGCGCTGA
TTTTCATGGGAGCGACCGCG

Downstream 100 bases:

>100_bases
CAGGCATAGAGGCAGCGGAAGTAGAGATAACCGAAGACTGGAAAGGAGACGTCATGCGCTGGAGTAAGCAGTTTTCCGTC
GTGGATTGCCACGCGGAAGG

Product: repressor-binding protein

Products: NA

Alternate protein names: Trp repressor-binding protein [H]

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MAQEKAKILVLIHSENGGTYELAKEVAAGIQSIGEVESVIKQVRASDKPALKDIPVATTQELTNYDGIAFGSPVYFANPS
PAIGAFLAGTVDLWTRHALEGVPATVFMSAGSGAGNELAIQSFRNSLAAHGMVLVPNGIRGAEAVDNTIPQGNTILGATS
LAGLKGSPRPSPSERQVARLQGSHFAKVALALRGVRPQPTARTEASRRVDINTALSEKGIVLPPPPAPVGNYTPFARSGN
LVFINQVALKDGAIVHAGKVGAGVSDDQAKEATRVTMLNVLAVLKDAVGGDLNRVRRTVQLTGLFNTTNDYADHAKLLNV
ASDLTVEVFGERGKHARAAVGAASLPVASPVEIQAIFEVE

Sequences:

>Translated_360_residues
MAQEKAKILVLIHSENGGTYELAKEVAAGIQSIGEVESVIKQVRASDKPALKDIPVATTQELTNYDGIAFGSPVYFANPS
PAIGAFLAGTVDLWTRHALEGVPATVFMSAGSGAGNELAIQSFRNSLAAHGMVLVPNGIRGAEAVDNTIPQGNTILGATS
LAGLKGSPRPSPSERQVARLQGSHFAKVALALRGVRPQPTARTEASRRVDINTALSEKGIVLPPPPAPVGNYTPFARSGN
LVFINQVALKDGAIVHAGKVGAGVSDDQAKEATRVTMLNVLAVLKDAVGGDLNRVRRTVQLTGLFNTTNDYADHAKLLNV
ASDLTVEVFGERGKHARAAVGAASLPVASPVEIQAIFEVE
>Mature_359_residues
AQEKAKILVLIHSENGGTYELAKEVAAGIQSIGEVESVIKQVRASDKPALKDIPVATTQELTNYDGIAFGSPVYFANPSP
AIGAFLAGTVDLWTRHALEGVPATVFMSAGSGAGNELAIQSFRNSLAAHGMVLVPNGIRGAEAVDNTIPQGNTILGATSL
AGLKGSPRPSPSERQVARLQGSHFAKVALALRGVRPQPTARTEASRRVDINTALSEKGIVLPPPPAPVGNYTPFARSGNL
VFINQVALKDGAIVHAGKVGAGVSDDQAKEATRVTMLNVLAVLKDAVGGDLNRVRRTVQLTGLFNTTNDYADHAKLLNVA
SDLTVEVFGERGKHARAAVGAASLPVASPVEIQAIFEVE

Specific function: Seems to enhance the formation and/or stability of noncovalent complexes between the trp repressor protein and operator-bearing DNA [H]

COG id: COG0655

COG function: function code R; Multimeric flavodoxin WrbA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain [H]

Homologues:

Organism=Escherichia coli, GI1787239, Length=197, Percent_Identity=41.6243654822335, Blast_Score=130, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6320235, Length=168, Percent_Identity=38.0952380952381, Blast_Score=95, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6319849, Length=217, Percent_Identity=32.7188940092166, Blast_Score=94, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6319526, Length=135, Percent_Identity=34.8148148148148, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008254
- InterPro:   IPR010089
- InterPro:   IPR005025 [H]

Pfam domain/function: PF03358 FMN_red [H]

EC number: NA

Molecular weight: Translated: 37540; Mature: 37409

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQEKAKILVLIHSENGGTYELAKEVAAGIQSIGEVESVIKQVRASDKPALKDIPVATTQ
CCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
ELTNYDGIAFGSPVYFANPSPAIGAFLAGTVDLWTRHALEGVPATVFMSAGSGAGNELAI
HHCCCCCEEECCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHH
QSFRNSLAAHGMVLVPNGIRGAEAVDNTIPQGNTILGATSLAGLKGSPRPSPSERQVARL
HHHHHHHHHCCEEEECCCCCCHHHHHHCCCCCCEEEEEHHHCCCCCCCCCCCCHHHHHHH
QGSHFAKVALALRGVRPQPTARTEASRRVDINTALSEKGIVLPPPPAPVGNYTPFARSGN
CCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHCCCCEEECCCCCCCCCCCCCCCCCC
LVFINQVALKDGAIVHAGKVGAGVSDDQAKEATRVTMLNVLAVLKDAVGGDLNRVRRTVQ
EEEEEEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHEEE
LTGLFNTTNDYADHAKLLNVASDLTVEVFGERGKHARAAVGAASLPVASPVEIQAIFEVE
EEEEECCCCCHHHHHHHHHHHHCCEEEEECCCCCHHHHHHCCCCCCCCCCCEEEEEEECC
>Mature Secondary Structure 
AQEKAKILVLIHSENGGTYELAKEVAAGIQSIGEVESVIKQVRASDKPALKDIPVATTQ
CCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
ELTNYDGIAFGSPVYFANPSPAIGAFLAGTVDLWTRHALEGVPATVFMSAGSGAGNELAI
HHCCCCCEEECCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHH
QSFRNSLAAHGMVLVPNGIRGAEAVDNTIPQGNTILGATSLAGLKGSPRPSPSERQVARL
HHHHHHHHHCCEEEECCCCCCHHHHHHCCCCCCEEEEEHHHCCCCCCCCCCCCHHHHHHH
QGSHFAKVALALRGVRPQPTARTEASRRVDINTALSEKGIVLPPPPAPVGNYTPFARSGN
CCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHCCCCEEECCCCCCCCCCCCCCCCCC
LVFINQVALKDGAIVHAGKVGAGVSDDQAKEATRVTMLNVLAVLKDAVGGDLNRVRRTVQ
EEEEEEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHEEE
LTGLFNTTNDYADHAKLLNVASDLTVEVFGERGKHARAAVGAASLPVASPVEIQAIFEVE
EEEEECCCCCHHHHHHHHHHHHCCEEEEECCCCCHHHHHHCCCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA