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The map label for this gene is int [H]

Identifier: 21242957

GI number: 21242957

Start: 2606638

End: 2607837

Strand: Direct

Name: int [H]

Synonym: XAC2222

Alternate gene names: 21242957

Gene position: 2606638-2607837 (Clockwise)

Preceding gene: 21242956

Following gene: 21242958

Centisome position: 50.36

GC content: 63.5

Gene sequence:

>1200_bases
ATGGCGAAGATCAAGCTCACCAAGTCCGCAGTCGATGCGGCACAACCCCAAGACAAGGCCATCGAACTGCGGGATACCGT
GGTGCCTGGCTTCCTGTGCAAGATCACACCGGCGGGCCGCAAGGTGTTCATGCTCCAGTACCGCACGAACGCCGGCGAGC
GCCGCAAGCCCGCCTTGGGCCAGTACGGAGAACTGACGGTCGATCAGGCGCGCACGATGGCGCAGGAGTGGCTGGCCGAG
GTGCGCAAGGGCGGCGACCCCAGCGCAGCCAAGAACGCCGCCCGCAAGGCACCGACCATGAGGGAGTTTTGCCATACCTT
CATGGAGGACTACTCCAAGCAGCGTAACAAGCCCAGCACGCAGCGCGGCTACCAGGGCGTCATTGACCGTTGCATCATCC
CGATCATGGGCCGGATGAAGGTGCAGGACGTGAAGCGCCCGGACGTGGCCGCGCTGATGAAGAGGCTGGCCTACAAGCAG
GCCGAGGCGAATCGCACCTTTGGCGTGCTGCGCAAGATGTTCAACCTGGCCGAAGTGTGGGGGCTGCGCCCTGACGGCAC
GAATCCGTGCCGCCACGTCCCGATGTACCCGCCCGGCAAGGAAACTCGGCTCATCGTGGATGACGAGTTGGTACGGATCT
TCCGTCACCTGGAGCATCTGGAAGCCGAGGGGCTGGAGAACTACGTCATCCCGCTGGCGATTCGCCTGCAATTCGAGTTC
GCCGCCCGTCGCTCCGAAATCTGCCCGCTCGAATGGGCATGGGTTGATCTGGAAAACCGCCGTGTCGTCTGGCCCGACAG
CAAGACCGGCGGCATTTCCAAGCCTATGAGCGAGGAAGCCTATCGGCTGCTGTCCACAGCGCCGCGCCGGGAAGGTTGCC
CCTATGTCCTGCCGTCGCCGAATGACCCGACCCGGCACATGACCCACGGCGAACACTACGGCGGCTGGACGCGCGTGCTG
AAGGCTGCTGGCGTGCCGCACGTTGGCACGCACGGTATCCGTCACCGAGCGACGACCGATATTGCCAATTCGGGCGTTCC
AACCAAGGTGGGCATGAAGCTCACAGGCCACAAGACTGTGGCGATGTTTATGCACTATGTTCATACCGAGGACAAGCCGG
TGCGGGATGCGGCCGAACTGGTGGCGAATCGGCGGCTGGCAATCACCGGGGCTTCCCGCTCTATGGAGGCAACAGCATGA

Upstream 100 bases:

>100_bases
GCGAGTTCAAGATATGCCGGTGCTTTCCGAAACTTGACCCGGCTTCCCCTCGCGTGGCTCCCATGCGGCTCCCGGAAACC
GGGCTTTCCGAGGAGTCATC

Downstream 100 bases:

>100_bases
AAAGGAAGATGCCTACGGCGGCGGGGAAAAGCGCCGCCTTACCGGCTGGCTATGCCGGCATCCACGGCGGCATCGTGGAA
CTGCTGGATGCGGCGCGCCA

Product: phage-related integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MAKIKLTKSAVDAAQPQDKAIELRDTVVPGFLCKITPAGRKVFMLQYRTNAGERRKPALGQYGELTVDQARTMAQEWLAE
VRKGGDPSAAKNAARKAPTMREFCHTFMEDYSKQRNKPSTQRGYQGVIDRCIIPIMGRMKVQDVKRPDVAALMKRLAYKQ
AEANRTFGVLRKMFNLAEVWGLRPDGTNPCRHVPMYPPGKETRLIVDDELVRIFRHLEHLEAEGLENYVIPLAIRLQFEF
AARRSEICPLEWAWVDLENRRVVWPDSKTGGISKPMSEEAYRLLSTAPRREGCPYVLPSPNDPTRHMTHGEHYGGWTRVL
KAAGVPHVGTHGIRHRATTDIANSGVPTKVGMKLTGHKTVAMFMHYVHTEDKPVRDAAELVANRRLAITGASRSMEATA

Sequences:

>Translated_399_residues
MAKIKLTKSAVDAAQPQDKAIELRDTVVPGFLCKITPAGRKVFMLQYRTNAGERRKPALGQYGELTVDQARTMAQEWLAE
VRKGGDPSAAKNAARKAPTMREFCHTFMEDYSKQRNKPSTQRGYQGVIDRCIIPIMGRMKVQDVKRPDVAALMKRLAYKQ
AEANRTFGVLRKMFNLAEVWGLRPDGTNPCRHVPMYPPGKETRLIVDDELVRIFRHLEHLEAEGLENYVIPLAIRLQFEF
AARRSEICPLEWAWVDLENRRVVWPDSKTGGISKPMSEEAYRLLSTAPRREGCPYVLPSPNDPTRHMTHGEHYGGWTRVL
KAAGVPHVGTHGIRHRATTDIANSGVPTKVGMKLTGHKTVAMFMHYVHTEDKPVRDAAELVANRRLAITGASRSMEATA
>Mature_398_residues
AKIKLTKSAVDAAQPQDKAIELRDTVVPGFLCKITPAGRKVFMLQYRTNAGERRKPALGQYGELTVDQARTMAQEWLAEV
RKGGDPSAAKNAARKAPTMREFCHTFMEDYSKQRNKPSTQRGYQGVIDRCIIPIMGRMKVQDVKRPDVAALMKRLAYKQA
EANRTFGVLRKMFNLAEVWGLRPDGTNPCRHVPMYPPGKETRLIVDDELVRIFRHLEHLEAEGLENYVIPLAIRLQFEFA
ARRSEICPLEWAWVDLENRRVVWPDSKTGGISKPMSEEAYRLLSTAPRREGCPYVLPSPNDPTRHMTHGEHYGGWTRVLK
AAGVPHVGTHGIRHRATTDIANSGVPTKVGMKLTGHKTVAMFMHYVHTEDKPVRDAAELVANRRLAITGASRSMEATA

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI145693166, Length=363, Percent_Identity=26.7217630853994, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1788690, Length=349, Percent_Identity=24.0687679083095, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 44915; Mature: 44784

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKIKLTKSAVDAAQPQDKAIELRDTVVPGFLCKITPAGRKVFMLQYRTNAGERRKPALG
CCEEEECHHHHHHCCCCCCCEEHHHHCCCCEEEEECCCCCEEEEEEEECCCCCCCCCCCC
QYGELTVDQARTMAQEWLAEVRKGGDPSAAKNAARKAPTMREFCHTFMEDYSKQRNKPST
CCCCEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCH
QRGYQGVIDRCIIPIMGRMKVQDVKRPDVAALMKRLAYKQAEANRTFGVLRKMFNLAEVW
HHHHHHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
GLRPDGTNPCRHVPMYPPGKETRLIVDDELVRIFRHLEHLEAEGLENYVIPLAIRLQFEF
CCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEHH
AARRSEICPLEWAWVDLENRRVVWPDSKTGGISKPMSEEAYRLLSTAPRREGCPYVLPSP
HHHCCCCCCCEEEEEEECCCEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEECCCC
NDPTRHMTHGEHYGGWTRVLKAAGVPHVGTHGIRHRATTDIANSGVPTKVGMKLTGHKTV
CCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEECCCHHH
AMFMHYVHTEDKPVRDAAELVANRRLAITGASRSMEATA
HHHHHHHHCCCCCHHHHHHHHHCCEEEEECCCCCCCCCC
>Mature Secondary Structure 
AKIKLTKSAVDAAQPQDKAIELRDTVVPGFLCKITPAGRKVFMLQYRTNAGERRKPALG
CEEEECHHHHHHCCCCCCCEEHHHHCCCCEEEEECCCCCEEEEEEEECCCCCCCCCCCC
QYGELTVDQARTMAQEWLAEVRKGGDPSAAKNAARKAPTMREFCHTFMEDYSKQRNKPST
CCCCEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCH
QRGYQGVIDRCIIPIMGRMKVQDVKRPDVAALMKRLAYKQAEANRTFGVLRKMFNLAEVW
HHHHHHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
GLRPDGTNPCRHVPMYPPGKETRLIVDDELVRIFRHLEHLEAEGLENYVIPLAIRLQFEF
CCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEHH
AARRSEICPLEWAWVDLENRRVVWPDSKTGGISKPMSEEAYRLLSTAPRREGCPYVLPSP
HHHCCCCCCCEEEEEEECCCEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEECCCC
NDPTRHMTHGEHYGGWTRVLKAAGVPHVGTHGIRHRATTDIANSGVPTKVGMKLTGHKTV
CCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEECCCHHH
AMFMHYVHTEDKPVRDAAELVANRRLAITGASRSMEATA
HHHHHHHHCCCCCHHHHHHHHHCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]