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The map label for this gene is czcB [H]

Identifier: 21242881

GI number: 21242881

Start: 2502758

End: 2504008

Strand: Direct

Name: czcB [H]

Synonym: XAC2145

Alternate gene names: 21242881

Gene position: 2502758-2504008 (Clockwise)

Preceding gene: 21242879

Following gene: 21242882

Centisome position: 48.36

GC content: 67.55

Gene sequence:

>1251_bases
ATGGGTGCCAGGCGATGCCGATGGACGCCGCTGCCGGCAGCGAGCGTAGATCCCTCGCCGATGCAACCGCGCCCTGCGTT
CGCGCATCGCCGACCGCGGGTGCAAGGCCTTCCCTCTCCCCGTTCGAGTCATCGCATGCCGTCCCCCTTCCCGCGTTCTA
CGCTGGCAGCTGCCTGTGTGTGCAGCTTGCTCGCTGGCTGCGGAGCAACGCCGCCGCCGGCCGCTCCCTCGCCGCTGCTG
ATCCACACCAACATGCAGGTGATGGTGCCGGCGCACTCGCCCTTGCGTGCCAGCCTGCGCGTGCAGGCGGTGCGCAGCCA
ACCCATCGCACCGCTGCTGCAGATGCCGGCCGTGATCGAGGTCTTGCCCGAGCGGCTGGTGCGGGTCGTGCCGCCGTTGG
CCGGGCGCGTGGTCGCACTGCCCAAGACCCTGGGCGACACCGTGCGTGCTGGCGATGTGCTGTGCGTGCTGGATTCTGCC
GAACTTGCCAGTGCCTACAGCGATGCCGGCAAGGCGCGCGCCACGCTGGAACAGGCACGTCTGGAACTTGCCCGGCAGAA
GGCGCTGGCAGCGGACAGCATTTCCGCTGCACGCGATCTGCAGGCAGCGCAGCAGGCCTTCGACAGCGCGCAGAACGATG
CACGGGCGGCCAGCGATCGCCTGGCCCAGCTGGGTGTTGCTGCGCAGGCGAGCTCGCACCGGCGCTATGTCGTGCGTGCG
CCCATTGCAGGCCGCTTGGTGGACCTGAGCGCTGCGCTGGGCGGCTTCTGGAACGACACGTCAGCGTCACTGATGACGGT
GGCCGATATCTCGCAGGTGTGGCTCACCGCCAGCGTGCCGGAACGCGAGATTGGCCAGGTCTTCGAAGGTCAGCCGGTCA
CTGCCAGCCTGGAGGCCTATCCAGCCCAACGCTTCGTCGGCCAGGTGCAACACCTGGATGATTTGCTCGACCCCGCCACC
CGCACATTGAAAGTCAGGGTGGCCTTAGAGAACCGCGATGGCCTGCTCAAGCCGGGCATGTTTGCGCGCGCCCAGTTCCA
CTCGCGTCCCCGACAGGCCCTGCTGGTGCCCGACAGCGCGCTCTTGCAGATGGGACTGTACACGCGGGTGTTCATCGAAA
CCGCGCCGTTCGCTTATCGCTCGCGCATCGTGGCCACCGGCCGCGCGATGGATGGGTATACCGAGATCCTGTCCGGCCTG
AAGGCCGGCGAGCGTGTGGTGATCAAGGACGGAGCCTTGCTCAATGATTGA

Upstream 100 bases:

>100_bases
CGGCTGGCACCATGCACGCCATCGACGCGGCTGCAGCACGCGTTGCAACTGCCCCAGCCCCGATGGCTGGCGCGCAACCT
CACACCTGTGGCGATGCGCC

Downstream 100 bases:

>100_bases
GGCGATCACCACCACCTGCTTCCAGCGGCGCGGCATCGTCTGGCTGGTCTTCGTACTCATTGCGTTATACGGCACATGGA
GCTGGACGCAGCTGCCGGTG

Product: cation efflux system protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 415

Protein sequence:

>416_residues
MGARRCRWTPLPAASVDPSPMQPRPAFAHRRPRVQGLPSPRSSHRMPSPFPRSTLAAACVCSLLAGCGATPPPAAPSPLL
IHTNMQVMVPAHSPLRASLRVQAVRSQPIAPLLQMPAVIEVLPERLVRVVPPLAGRVVALPKTLGDTVRAGDVLCVLDSA
ELASAYSDAGKARATLEQARLELARQKALAADSISAARDLQAAQQAFDSAQNDARAASDRLAQLGVAAQASSHRRYVVRA
PIAGRLVDLSAALGGFWNDTSASLMTVADISQVWLTASVPEREIGQVFEGQPVTASLEAYPAQRFVGQVQHLDDLLDPAT
RTLKVRVALENRDGLLKPGMFARAQFHSRPRQALLVPDSALLQMGLYTRVFIETAPFAYRSRIVATGRAMDGYTEILSGL
KAGERVVIKDGALLND

Sequences:

>Translated_416_residues
MGARRCRWTPLPAASVDPSPMQPRPAFAHRRPRVQGLPSPRSSHRMPSPFPRSTLAAACVCSLLAGCGATPPPAAPSPLL
IHTNMQVMVPAHSPLRASLRVQAVRSQPIAPLLQMPAVIEVLPERLVRVVPPLAGRVVALPKTLGDTVRAGDVLCVLDSA
ELASAYSDAGKARATLEQARLELARQKALAADSISAARDLQAAQQAFDSAQNDARAASDRLAQLGVAAQASSHRRYVVRA
PIAGRLVDLSAALGGFWNDTSASLMTVADISQVWLTASVPEREIGQVFEGQPVTASLEAYPAQRFVGQVQHLDDLLDPAT
RTLKVRVALENRDGLLKPGMFARAQFHSRPRQALLVPDSALLQMGLYTRVFIETAPFAYRSRIVATGRAMDGYTEILSGL
KAGERVVIKDGALLND
>Mature_415_residues
GARRCRWTPLPAASVDPSPMQPRPAFAHRRPRVQGLPSPRSSHRMPSPFPRSTLAAACVCSLLAGCGATPPPAAPSPLLI
HTNMQVMVPAHSPLRASLRVQAVRSQPIAPLLQMPAVIEVLPERLVRVVPPLAGRVVALPKTLGDTVRAGDVLCVLDSAE
LASAYSDAGKARATLEQARLELARQKALAADSISAARDLQAAQQAFDSAQNDARAASDRLAQLGVAAQASSHRRYVVRAP
IAGRLVDLSAALGGFWNDTSASLMTVADISQVWLTASVPEREIGQVFEGQPVTASLEAYPAQRFVGQVQHLDDLLDPATR
TLKVRVALENRDGLLKPGMFARAQFHSRPRQALLVPDSALLQMGLYTRVFIETAPFAYRSRIVATGRAMDGYTEILSGLK
AGERVVIKDGALLND

Specific function: CzcA and CzcB together would act in zinc efflux nearly as effectively as the complete czc efflux system (CzcABC). The CzcB protein is thought to funnel zinc cations to the CzcA transport protein [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=337, Percent_Identity=28.486646884273, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1786787, Length=186, Percent_Identity=32.258064516129, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1789929, Length=307, Percent_Identity=26.3843648208469, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005695
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 44540; Mature: 44409

Theoretical pI: Translated: 10.50; Mature: 10.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGARRCRWTPLPAASVDPSPMQPRPAFAHRRPRVQGLPSPRSSHRMPSPFPRSTLAAACV
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
CSLLAGCGATPPPAAPSPLLIHTNMQVMVPAHSPLRASLRVQAVRSQPIAPLLQMPAVIE
HHHHHHCCCCCCCCCCCCEEEECCCEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHH
VLPERLVRVVPPLAGRVVALPKTLGDTVRAGDVLCVLDSAELASAYSDAGKARATLEQAR
HHHHHHHHHCCCCCCCEEECCHHHCCHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHH
LELARQKALAADSISAARDLQAAQQAFDSAQNDARAASDRLAQLGVAAQASSHRRYVVRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
PIAGRLVDLSAALGGFWNDTSASLMTVADISQVWLTASVPEREIGQVFEGQPVTASLEAY
CCCCHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHEECCCCHHHHHHHHCCCCCEEHHHHC
PAQRFVGQVQHLDDLLDPATRTLKVRVALENRDGLLKPGMFARAQFHSRPRQALLVPDSA
CHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHCCCCCEEECCCHH
LLQMGLYTRVFIETAPFAYRSRIVATGRAMDGYTEILSGLKAGERVVIKDGALLND
HHHHHHHHEEEHCCCCHHHHHHHEECCCCCCCHHHHHHHHCCCCEEEEECCCCCCC
>Mature Secondary Structure 
GARRCRWTPLPAASVDPSPMQPRPAFAHRRPRVQGLPSPRSSHRMPSPFPRSTLAAACV
CCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
CSLLAGCGATPPPAAPSPLLIHTNMQVMVPAHSPLRASLRVQAVRSQPIAPLLQMPAVIE
HHHHHHCCCCCCCCCCCCEEEECCCEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHH
VLPERLVRVVPPLAGRVVALPKTLGDTVRAGDVLCVLDSAELASAYSDAGKARATLEQAR
HHHHHHHHHCCCCCCCEEECCHHHCCHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHH
LELARQKALAADSISAARDLQAAQQAFDSAQNDARAASDRLAQLGVAAQASSHRRYVVRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
PIAGRLVDLSAALGGFWNDTSASLMTVADISQVWLTASVPEREIGQVFEGQPVTASLEAY
CCCCHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHEECCCCHHHHHHHHCCCCCEEHHHHC
PAQRFVGQVQHLDDLLDPATRTLKVRVALENRDGLLKPGMFARAQFHSRPRQALLVPDSA
CHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHCCCCCEEECCCHH
LLQMGLYTRVFIETAPFAYRSRIVATGRAMDGYTEILSGLKAGERVVIKDGALLND
HHHHHHHHEEEHCCCCHHHHHHHEECCCCCCCHHHHHHHHCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8829543 [H]