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The map label for this gene is zupT

Identifier: 21242849

GI number: 21242849

Start: 2471843

End: 2472661

Strand: Reverse

Name: zupT

Synonym: XAC2114

Alternate gene names: 21242849

Gene position: 2472661-2471843 (Counterclockwise)

Preceding gene: 21242850

Following gene: 21242848

Centisome position: 47.78

GC content: 62.52

Gene sequence:

>819_bases
ATGCTTGCAGTGTCATCGCACAATCTCTGGATCGCGCTTGCGGTCACGCTGGCCGCCGGGCTGGCGACCGGGCTCGGCAG
CCTCATGGTGGTGTTCGCCAAAAAGCCCAATCCGCGGCTGTTGGCGTTCGGTCTGGCCTTCGCCGGCGGCGCAATGGTGT
ACGTGTCGCTCACCGAGATCCTCAACAAGTCGATCGCCGCGTTTTCCCAGGCCTACAACGACAAGCTCGGCTTTACCTTC
GGCACACTGACCTTTCTGGGCGGCATGCTGCTGATCATGGTGATCGACCGCCTGGTGCCGAATCCGCACCAGAGTTTGTC
CAGCGACGATCCGCAGTTTCGCGAAGACAACCGGGCCTATATCCGCCGGGTTGGCCTGATGACCGCCGTCGCGATCACCG
CGCACAATTTTCCGGAAGGATTGGCGACTTTCTTCGCAACGCTCGAAAGCCCGGCGGTCGGCATGCCGCTGGCGTTCGCG
ATCGCCATCCACAATATTCCCGAAGGCATTGCGATCGCGGTGCCGGTGTATTTCGCCACGCGCAACAAGTTCTATGCGGT
GGGCGCCAGCCTGCTCAGCGGGCTGGCCGAACCGGTCGGTGCAGGCATCGGATATCTGGCCTTGTTCAGCGTGCTCTCGG
ACGCGGTCTTCGGCACCGTGTTCGGGCTGATCTCCGGGGTCATGGTGTTTCTGGCACTGGACGAGTTACTGCCGGCTGCC
AAGCGTTACGCCCAGGGTCACGAGACCGTGTACGGCTTGGTCTCGGGCATGGGAACGCTGGCGATCAGCCTGGTGTTGTT
CCGCTTCGCAACGCCGTGA

Upstream 100 bases:

>100_bases
CATGGCCATCCTGCTTCCCCGGAGGTCGTGCGTATCTCGCGAGCTGCAGTTGCCACGCTCTCCGCAGGAAGTTCTTCATT
CCACCAGGACGTCGCGCCAC

Downstream 100 bases:

>100_bases
AGCGCGTCGTGCGCTGGCATCTCATGATGACCTGGCCGCAAAGTCTGCTGCGCCAGGGGCTGACAGCCGTCTTCAGCGAC
ACCATCGCTGTCTTGTCGAT

Product: zinc transporter ZupT

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MLAVSSHNLWIALAVTLAAGLATGLGSLMVVFAKKPNPRLLAFGLAFAGGAMVYVSLTEILNKSIAAFSQAYNDKLGFTF
GTLTFLGGMLLIMVIDRLVPNPHQSLSSDDPQFREDNRAYIRRVGLMTAVAITAHNFPEGLATFFATLESPAVGMPLAFA
IAIHNIPEGIAIAVPVYFATRNKFYAVGASLLSGLAEPVGAGIGYLALFSVLSDAVFGTVFGLISGVMVFLALDELLPAA
KRYAQGHETVYGLVSGMGTLAISLVLFRFATP

Sequences:

>Translated_272_residues
MLAVSSHNLWIALAVTLAAGLATGLGSLMVVFAKKPNPRLLAFGLAFAGGAMVYVSLTEILNKSIAAFSQAYNDKLGFTF
GTLTFLGGMLLIMVIDRLVPNPHQSLSSDDPQFREDNRAYIRRVGLMTAVAITAHNFPEGLATFFATLESPAVGMPLAFA
IAIHNIPEGIAIAVPVYFATRNKFYAVGASLLSGLAEPVGAGIGYLALFSVLSDAVFGTVFGLISGVMVFLALDELLPAA
KRYAQGHETVYGLVSGMGTLAISLVLFRFATP
>Mature_272_residues
MLAVSSHNLWIALAVTLAAGLATGLGSLMVVFAKKPNPRLLAFGLAFAGGAMVYVSLTEILNKSIAAFSQAYNDKLGFTF
GTLTFLGGMLLIMVIDRLVPNPHQSLSSDDPQFREDNRAYIRRVGLMTAVAITAHNFPEGLATFFATLESPAVGMPLAFA
IAIHNIPEGIAIAVPVYFATRNKFYAVGASLLSGLAEPVGAGIGYLALFSVLSDAVFGTVFGLISGVMVFLALDELLPAA
KRYAQGHETVYGLVSGMGTLAISLVLFRFATP

Specific function: Mediates zinc uptake. May also transport other divalent cations

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily

Homologues:

Organism=Escherichia coli, GI1789419, Length=264, Percent_Identity=38.2575757575758, Blast_Score=154, Evalue=8e-39,
Organism=Caenorhabditis elegans, GI17507805, Length=305, Percent_Identity=25.9016393442623, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24652846, Length=158, Percent_Identity=31.6455696202532, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ZUPT_XANAC (Q8PKQ5)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_642431.1
- GeneID:   1156185
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC2114
- NMPDR:   fig|190486.1.peg.2075
- HOGENOM:   HBG620552
- OMA:   FREDNRA
- ProtClustDB:   PRK04201
- BioCyc:   XAXO190486:XAC2114-MONOMER
- HAMAP:   MF_00548
- InterPro:   IPR003689

Pfam domain/function: PF02535 Zip

EC number: NA

Molecular weight: Translated: 28665; Mature: 28665

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: PS00485 A_DEAMINASE

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x101540a8)-; HASH(0x1033678c)-; HASH(0xe5ba230)-; HASH(0xffd0cc4)-; HASH(0x10321cd4)-; HASH(0x101bd288)-; HASH(0x10367704)-; HASH(0xff84e94)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAVSSHNLWIALAVTLAAGLATGLGSLMVVFAKKPNPRLLAFGLAFAGGAMVYVSLTEI
CCEECCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCEEEEHHHHHCCHHHHHHHHHH
LNKSIAAFSQAYNDKLGFTFGTLTFLGGMLLIMVIDRLVPNPHQSLSSDDPQFREDNRAY
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCHHHCCHHH
IRRVGLMTAVAITAHNFPEGLATFFATLESPAVGMPLAFAIAIHNIPEGIAIAVPVYFAT
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEEEEEHH
RNKFYAVGASLLSGLAEPVGAGIGYLALFSVLSDAVFGTVFGLISGVMVFLALDELLPAA
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRYAQGHETVYGLVSGMGTLAISLVLFRFATP
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MLAVSSHNLWIALAVTLAAGLATGLGSLMVVFAKKPNPRLLAFGLAFAGGAMVYVSLTEI
CCEECCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCEEEEHHHHHCCHHHHHHHHHH
LNKSIAAFSQAYNDKLGFTFGTLTFLGGMLLIMVIDRLVPNPHQSLSSDDPQFREDNRAY
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCHHHCCHHH
IRRVGLMTAVAITAHNFPEGLATFFATLESPAVGMPLAFAIAIHNIPEGIAIAVPVYFAT
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEEEEEHH
RNKFYAVGASLLSGLAEPVGAGIGYLALFSVLSDAVFGTVFGLISGVMVFLALDELLPAA
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRYAQGHETVYGLVSGMGTLAISLVLFRFATP
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12024217