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The map label for this gene is pgsA [H]

Identifier: 21242832

GI number: 21242832

Start: 2442689

End: 2443321

Strand: Direct

Name: pgsA [H]

Synonym: XAC2093

Alternate gene names: 21242832

Gene position: 2442689-2443321 (Clockwise)

Preceding gene: 21242831

Following gene: 21242833

Centisome position: 47.2

GC content: 60.66

Gene sequence:

>633_bases
ATGAAGTTGACCATCCCCACGTGGCTGACACTGCTGAGGATCGTGATGATCCCGGTGTTGGTCGTGGTGTTCTACCTGCC
CTACACGTGGACGAACTTCGCGTCCGCCGGCGTGTTTGCGCTGGCCGCCATCACCGACTGGCTGGATGGCTGGGTCGCGC
GGCGTTATCACCAATATTCCGCATTCGGCGCATTTCTGGACCCGGTCGCCGACAAGTTGATGGTCGCGGTGGCGCTGTTC
CTGATTGTGCAGGGCCATCCCACGCCGTGGATGGCGTTCTGGGCGGCAGTCATCGTCGGACGCGAGATTGCCGTCTCTGC
ACTCCGCGAATGGATGGCCGAGATCGGCCAGCGCGCCAAGGTGCGCGTGGCGGCCATCGGCAAGATCAAAACCACCGCAC
AAATGGTGGCGTTGCTGTGCCTGTTGTATTCGGTCACCCCAGGGCAGATGCCTACGCATGAAATCTGGCTGGGCAACCTG
ATTTTTCGTGCGGGCTACTGGACGCTGGCCATTGCGGCCTTGCTGACGCTGTGGTCAGGGTTTCAGTATCTGCAGGCCGC
GTGGCCAAGCCTGCGCGCCGACGAGAAAGCAGCGATCAGCAACAAGCCGAAAAAAATCGAAAGCAACAGTTGA

Upstream 100 bases:

>100_bases
TTGCACGGGTGGAGGGGGTCAATGCCGCACTTGCCGCGCGAATCTACGCTAACCTGCACGGGCTGGCGCTTCCCGATGCG
GCAGGCGAGGCAAGTCCGCA

Downstream 100 bases:

>100_bases
CAGCTATCCCGTTCACTGTAGAATTTCGCCTCCCAAGCGGGAATAGCTCAGTTGGTAGAGCGCAACCTTGCCAAGGTTGA
GGTCGCGAGTTCGAGTCTCG

Product: CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MKLTIPTWLTLLRIVMIPVLVVVFYLPYTWTNFASAGVFALAAITDWLDGWVARRYHQYSAFGAFLDPVADKLMVAVALF
LIVQGHPTPWMAFWAAVIVGREIAVSALREWMAEIGQRAKVRVAAIGKIKTTAQMVALLCLLYSVTPGQMPTHEIWLGNL
IFRAGYWTLAIAALLTLWSGFQYLQAAWPSLRADEKAAISNKPKKIESNS

Sequences:

>Translated_210_residues
MKLTIPTWLTLLRIVMIPVLVVVFYLPYTWTNFASAGVFALAAITDWLDGWVARRYHQYSAFGAFLDPVADKLMVAVALF
LIVQGHPTPWMAFWAAVIVGREIAVSALREWMAEIGQRAKVRVAAIGKIKTTAQMVALLCLLYSVTPGQMPTHEIWLGNL
IFRAGYWTLAIAALLTLWSGFQYLQAAWPSLRADEKAAISNKPKKIESNS
>Mature_210_residues
MKLTIPTWLTLLRIVMIPVLVVVFYLPYTWTNFASAGVFALAAITDWLDGWVARRYHQYSAFGAFLDPVADKLMVAVALF
LIVQGHPTPWMAFWAAVIVGREIAVSALREWMAEIGQRAKVRVAAIGKIKTTAQMVALLCLLYSVTPGQMPTHEIWLGNL
IFRAGYWTLAIAALLTLWSGFQYLQAAWPSLRADEKAAISNKPKKIESNS

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=194, Percent_Identity=51.5463917525773, Blast_Score=181, Evalue=3e-47,
Organism=Saccharomyces cerevisiae, GI6320059, Length=208, Percent_Identity=32.2115384615385, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 23440; Mature: 23440

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTIPTWLTLLRIVMIPVLVVVFYLPYTWTNFASAGVFALAAITDWLDGWVARRYHQYS
CCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFGAFLDPVADKLMVAVALFLIVQGHPTPWMAFWAAVIVGREIAVSALREWMAEIGQRAK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
VRVAAIGKIKTTAQMVALLCLLYSVTPGQMPTHEIWLGNLIFRAGYWTLAIAALLTLWSG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FQYLQAAWPSLRADEKAAISNKPKKIESNS
HHHHHHHCCCCCCCCHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKLTIPTWLTLLRIVMIPVLVVVFYLPYTWTNFASAGVFALAAITDWLDGWVARRYHQYS
CCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFGAFLDPVADKLMVAVALFLIVQGHPTPWMAFWAAVIVGREIAVSALREWMAEIGQRAK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
VRVAAIGKIKTTAQMVALLCLLYSVTPGQMPTHEIWLGNLIFRAGYWTLAIAALLTLWSG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FQYLQAAWPSLRADEKAAISNKPKKIESNS
HHHHHHHCCCCCCCCHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA