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The map label for this gene is glk

Identifier: 21242809

GI number: 21242809

Start: 2418338

End: 2419345

Strand: Reverse

Name: glk

Synonym: XAC2070

Alternate gene names: 21242809

Gene position: 2419345-2418338 (Counterclockwise)

Preceding gene: 21242810

Following gene: 21242808

Centisome position: 46.75

GC content: 67.06

Gene sequence:

>1008_bases
ATGACCGCTCCTTCCAAGCCGGTGCTGGTTGCCGATATCGGCGGTACCAATGCGCGCTTCGCGCTGGCCGATGTCGACGC
CTCGGTGCCGTTGCTGGATGACACCTCGCGCGAATTTGCGGTGGTGGATTTCGGTTCGCTGGGCGAAGCGGCGCGCTATT
ACCTGGACCAGATCGGCGTGCAGGCCACCCAGGGCGTGTTCGCCGTGGCGGGCCGCGTGGACGGCGACGAGGCACGCATC
ACCAACCATCCCTGGGTGATCTCGCGCTCGCGCACCGCCACCATGCTGGGTTTCAGTACCTTGCATCTGATCAACGACTT
TGCCGCGCAGGCGATGGCGATCAGCCTGCTGCGTCCACAGGACGTGGTGCAGGTAGGCGGCGCCAGCTGGCGTCCGGCAC
CGATCGATCAAGCGCGCAACTATGGCGTGATCGGCCCGGGCACCGGCCTGGGCGTGGGCGGCCTGATCATCCGCAACGGG
CGCTGCTTTCCGCTGGAAACCGAAGGCGGCCATGTCAGCTTCCCGCCCGGCACGCCGGAAGAAATCCGCATCCTGGAAAT
CCTGTCCGAGCAGTTCGGCCGGGTCTCCAACGAGCGGCTGATCTGCGGTCCGGGCCTGGTCAATATCCATCGCGCGTTGA
GCGAGATCGCGGGGGTCGATCCGGGCCCGCTGCAACCCAAGGACATCACCGCACGCGCGGCTGCGGGCGACCCGCGGTCC
TCGCGCACCATCGATCTGTTCTGCGCCATCTTCGGTGCGATCGCCGGCGACATGGTGCTGATGCAGGGCGCCTGGGACGG
CGTGTTCCTCACCGGCGGGCTGGTGCCCAAGGTGCTGGATTCGCTGCAGCATTCCGGCTTTCGCCAGCGCTTCGAACACA
AGGGCCGTTTCTCCGCGATCATGTCGAAGGTGCCATCGCTGGCGGTCATGCACCCGCATGCCGGCCTGCTGGGCGCCGCC
GCCTACGCGGTGGATGCACAACGTCAGCACCCCGGGGAGCAGCGATGA

Upstream 100 bases:

>100_bases
ACGCCGCGCTGCCGCTGCAGCCCTACCCGGCCGGCAGCTGGGGTCCCGAATCGGCCGCCCACTTCCTGCCCCCGGCCACC
GACGCACAGGGAAACAACGC

Downstream 100 bases:

>100_bases
ATCTGCAGGACAACCCGCGCATCACCCTGGTGCGCTACGACGACCCGGCCGAATGGACCGAGGCGGTGGCCAGCGAAATG
GCCGACCTGCTGGAACAGGA

Product: glucokinase

Products: NA

Alternate protein names: Glucose kinase

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MTAPSKPVLVADIGGTNARFALADVDASVPLLDDTSREFAVVDFGSLGEAARYYLDQIGVQATQGVFAVAGRVDGDEARI
TNHPWVISRSRTATMLGFSTLHLINDFAAQAMAISLLRPQDVVQVGGASWRPAPIDQARNYGVIGPGTGLGVGGLIIRNG
RCFPLETEGGHVSFPPGTPEEIRILEILSEQFGRVSNERLICGPGLVNIHRALSEIAGVDPGPLQPKDITARAAAGDPRS
SRTIDLFCAIFGAIAGDMVLMQGAWDGVFLTGGLVPKVLDSLQHSGFRQRFEHKGRFSAIMSKVPSLAVMHPHAGLLGAA
AYAVDAQRQHPGEQR

Sequences:

>Translated_335_residues
MTAPSKPVLVADIGGTNARFALADVDASVPLLDDTSREFAVVDFGSLGEAARYYLDQIGVQATQGVFAVAGRVDGDEARI
TNHPWVISRSRTATMLGFSTLHLINDFAAQAMAISLLRPQDVVQVGGASWRPAPIDQARNYGVIGPGTGLGVGGLIIRNG
RCFPLETEGGHVSFPPGTPEEIRILEILSEQFGRVSNERLICGPGLVNIHRALSEIAGVDPGPLQPKDITARAAAGDPRS
SRTIDLFCAIFGAIAGDMVLMQGAWDGVFLTGGLVPKVLDSLQHSGFRQRFEHKGRFSAIMSKVPSLAVMHPHAGLLGAA
AYAVDAQRQHPGEQR
>Mature_334_residues
TAPSKPVLVADIGGTNARFALADVDASVPLLDDTSREFAVVDFGSLGEAARYYLDQIGVQATQGVFAVAGRVDGDEARIT
NHPWVISRSRTATMLGFSTLHLINDFAAQAMAISLLRPQDVVQVGGASWRPAPIDQARNYGVIGPGTGLGVGGLIIRNGR
CFPLETEGGHVSFPPGTPEEIRILEILSEQFGRVSNERLICGPGLVNIHRALSEIAGVDPGPLQPKDITARAAAGDPRSS
RTIDLFCAIFGAIAGDMVLMQGAWDGVFLTGGLVPKVLDSLQHSGFRQRFEHKGRFSAIMSKVPSLAVMHPHAGLLGAAA
YAVDAQRQHPGEQR

Specific function: Not Highly Important In E.Coli As Glucose Is Transported Into The Cell By The Pts System Already As Glucose 6-Phosphate. [C]

COG id: COG0837

COG function: function code G; Glucokinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial glucokinase family

Homologues:

Organism=Escherichia coli, GI1788732, Length=319, Percent_Identity=41.692789968652, Blast_Score=236, Evalue=2e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLK_XANAC (Q8PKU2)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_642391.1
- ProteinModelPortal:   Q8PKU2
- GeneID:   1156141
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC2070
- HOGENOM:   HBG644410
- OMA:   VDIGGTH
- ProtClustDB:   PRK00292
- BioCyc:   XAXO190486:XAC2070-MONOMER
- BRENDA:   2.7.1.2
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_00524
- InterPro:   IPR003836
- TIGRFAMs:   TIGR00749

Pfam domain/function: PF02685 Glucokinase

EC number: =2.7.1.2

Molecular weight: Translated: 35518; Mature: 35387

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPSKPVLVADIGGTNARFALADVDASVPLLDDTSREFAVVDFGSLGEAARYYLDQIGV
CCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCC
QATQGVFAVAGRVDGDEARITNHPWVISRSRTATMLGFSTLHLINDFAAQAMAISLLRPQ
HHHCCEEEEEECCCCCCCEECCCCEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCH
DVVQVGGASWRPAPIDQARNYGVIGPGTGLGVGGLIIRNGRCFPLETEGGHVSFPPGTPE
HHHHHCCCCCCCCCHHHHCCCCEECCCCCCCCCEEEEECCEEEEEECCCCEEECCCCCHH
EIRILEILSEQFGRVSNERLICGPGLVNIHRALSEIAGVDPGPLQPKDITARAAAGDPRS
HHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCC
SRTIDLFCAIFGAIAGDMVLMQGAWDGVFLTGGLVPKVLDSLQHSGFRQRFEHKGRFSAI
CCHHHHHHHHHHHHHCCEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHH
MSKVPSLAVMHPHAGLLGAAAYAVDAQRQHPGEQR
HHHCCCEEEECCCCCHHHHHHHHHCHHHCCCCCCC
>Mature Secondary Structure 
TAPSKPVLVADIGGTNARFALADVDASVPLLDDTSREFAVVDFGSLGEAARYYLDQIGV
CCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCC
QATQGVFAVAGRVDGDEARITNHPWVISRSRTATMLGFSTLHLINDFAAQAMAISLLRPQ
HHHCCEEEEEECCCCCCCEECCCCEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCH
DVVQVGGASWRPAPIDQARNYGVIGPGTGLGVGGLIIRNGRCFPLETEGGHVSFPPGTPE
HHHHHCCCCCCCCCHHHHCCCCEECCCCCCCCCEEEEECCEEEEEECCCCEEECCCCCHH
EIRILEILSEQFGRVSNERLICGPGLVNIHRALSEIAGVDPGPLQPKDITARAAAGDPRS
HHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCC
SRTIDLFCAIFGAIAGDMVLMQGAWDGVFLTGGLVPKVLDSLQHSGFRQRFEHKGRFSAI
CCHHHHHHHHHHHHHCCEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHH
MSKVPSLAVMHPHAGLLGAAAYAVDAQRQHPGEQR
HHHCCCEEEECCCCCHHHHHHHHHCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217