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The map label for this gene is pgl [H]

Identifier: 21242808

GI number: 21242808

Start: 2417622

End: 2418341

Strand: Reverse

Name: pgl [H]

Synonym: XAC2069

Alternate gene names: 21242808

Gene position: 2418341-2417622 (Counterclockwise)

Preceding gene: 21242809

Following gene: 21242807

Centisome position: 46.73

GC content: 67.92

Gene sequence:

>720_bases
ATGAATCTGCAGGACAACCCGCGCATCACCCTGGTGCGCTACGACGACCCGGCCGAATGGACCGAGGCGGTGGCCAGCGA
AATGGCCGACCTGCTGGAACAGGAGATCTCCCGGCGTGGCCAAGCACGCATGCTGCTGTCCGGCGGCACCACGCCAGCGC
CGGTGTACGAGTCCCTCGCCCACCGGCCGCTGGACTGGTCGCGGGTGGAAGTGGGCCTGGTCGATGAACGCTGGTTGTCG
CCGCAGGATCAGGACAGCAATGCCTGGCTGGTCAATCACAGCTTCCTGACCCACGCATCGGCCGCGACCTTCATTCCGCT
GGTCCGTCCGGGCAAGCAACTGCCCGAATGCGTGCACACCGCCAACCTGCAGGCCAGGCATGCCGAACCGGCCTGCCTGG
CAGTGCTGGGCATGGGCGGCGACGGGCACACCGCGTCGTTGTTCCCGGGTGCCACCGACCTGCCGAAGGCGCTCGCCAGC
CCGCAGCCGTACGCATCGCTGGATGCCACCGGCTGCCCGGGCTCGAACCAATGGCCGTTGCGCATCACCCTGACGCCCGC
AGGGCTTGCCAGCATTCCAACGCGCCTGCTGCTGTTGCGTGGCAAGCAGAAGCTGGACGTGCTGCAGGCCGCGTTGGCCG
GCGACGACATCAATGAGTATCCGATCCGCGTGGCGCTGCAGCAGCCCGGTCCGCGGTTGCGGGTGCATTGGTGCGCTTGA

Upstream 100 bases:

>100_bases
CGAAGGTGCCATCGCTGGCGGTCATGCACCCGCATGCCGGCCTGCTGGGCGCCGCCGCCTACGCGGTGGATGCACAACGT
CAGCACCCCGGGGAGCAGCG

Downstream 100 bases:

>100_bases
GTGCGAGTCCCTCGCAAGAGCCCGCACATCCTTGTGCGGGGATTTAAGAAAAACGCTTTCTTCCCCCGTTTCTCATAGCC
GGTAGCCAATGAGCCTGCAT

Product: 6-phosphogluconolactonase

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MNLQDNPRITLVRYDDPAEWTEAVASEMADLLEQEISRRGQARMLLSGGTTPAPVYESLAHRPLDWSRVEVGLVDERWLS
PQDQDSNAWLVNHSFLTHASAATFIPLVRPGKQLPECVHTANLQARHAEPACLAVLGMGGDGHTASLFPGATDLPKALAS
PQPYASLDATGCPGSNQWPLRITLTPAGLASIPTRLLLLRGKQKLDVLQAALAGDDINEYPIRVALQQPGPRLRVHWCA

Sequences:

>Translated_239_residues
MNLQDNPRITLVRYDDPAEWTEAVASEMADLLEQEISRRGQARMLLSGGTTPAPVYESLAHRPLDWSRVEVGLVDERWLS
PQDQDSNAWLVNHSFLTHASAATFIPLVRPGKQLPECVHTANLQARHAEPACLAVLGMGGDGHTASLFPGATDLPKALAS
PQPYASLDATGCPGSNQWPLRITLTPAGLASIPTRLLLLRGKQKLDVLQAALAGDDINEYPIRVALQQPGPRLRVHWCA
>Mature_239_residues
MNLQDNPRITLVRYDDPAEWTEAVASEMADLLEQEISRRGQARMLLSGGTTPAPVYESLAHRPLDWSRVEVGLVDERWLS
PQDQDSNAWLVNHSFLTHASAATFIPLVRPGKQLPECVHTANLQARHAEPACLAVLGMGGDGHTASLFPGATDLPKALAS
PQPYASLDATGCPGSNQWPLRITLTPAGLASIPTRLLLLRGKQKLDVLQAALAGDDINEYPIRVALQQPGPRLRVHWCA

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI52145310, Length=227, Percent_Identity=27.3127753303965, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900 [H]

Pfam domain/function: NA

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 25997; Mature: 25997

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLQDNPRITLVRYDDPAEWTEAVASEMADLLEQEISRRGQARMLLSGGTTPAPVYESLA
CCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHH
HRPLDWSRVEVGLVDERWLSPQDQDSNAWLVNHSFLTHASAATFIPLVRPGKQLPECVHT
CCCCCCCEEEEEEEHHHCCCCCCCCCCEEEEECHHHHHCCHHHEEECCCCCHHHHHHHHH
ANLQARHAEPACLAVLGMGGDGHTASLFPGATDLPKALASPQPYASLDATGCPGSNQWPL
CCCCCCCCCCEEEEEEECCCCCCEEEECCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCE
RITLTPAGLASIPTRLLLLRGKQKLDVLQAALAGDDINEYPIRVALQQPGPRLRVHWCA
EEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEECC
>Mature Secondary Structure
MNLQDNPRITLVRYDDPAEWTEAVASEMADLLEQEISRRGQARMLLSGGTTPAPVYESLA
CCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHH
HRPLDWSRVEVGLVDERWLSPQDQDSNAWLVNHSFLTHASAATFIPLVRPGKQLPECVHT
CCCCCCCEEEEEEEHHHCCCCCCCCCCEEEEECHHHHHCCHHHEEECCCCCHHHHHHHHH
ANLQARHAEPACLAVLGMGGDGHTASLFPGATDLPKALASPQPYASLDATGCPGSNQWPL
CCCCCCCCCCEEEEEEECCCCCCEEEECCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCE
RITLTPAGLASIPTRLLLLRGKQKLDVLQAALAGDDINEYPIRVALQQPGPRLRVHWCA
EEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]