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The map label for this gene is ppsA [H]

Identifier: 21242785

GI number: 21242785

Start: 2385040

End: 2387418

Strand: Reverse

Name: ppsA [H]

Synonym: XAC2041

Alternate gene names: 21242785

Gene position: 2387418-2385040 (Counterclockwise)

Preceding gene: 21242789

Following gene: 21242784

Centisome position: 46.13

GC content: 63.05

Gene sequence:

>2379_bases
TTGAACGAGAATATCCTGTGGTTGCATGAGCTACGCCTGGCCGACCTGGCCCGCGTGGGCGGTAAAAATTCCTCGCTTGG
CGAGATGATCGGCAACCTGGCTGGGTTGGGCGTCTCGGTTCCTGGTGGATATGCGACCACCGCGGAAGCTTTCAAGGACT
TCATCGCGCACAACGATCTGTCCAAGCGCATCTTCGACAGGCTGGCAACGCTGGATGTCGAAGACGTCAATGCACTCACG
CTGGCCGGCAAGGAAATCCGCGGCTGGGTGATCGATGCCCCACTGCAGCCGGACCTGGACCGCGACATCCGCAGCGCCTA
CGCCCAGTTGTGCGCCGAGAACGGCGGCGGCGACGTTGCCGTGGCCGTGCGCTCCTCGGCAACCGCCGAGGACCTTCCGG
ACGCCTCGTTCGCAGGCCAGCAGGAGACCTTCCTCAATGTGACCGGCGCCGACGATGTGGTGCACAAGGTCAAGGAAGTG
TTCGCCAGCCTCTACAACGATCGTGCGATTGCCTATCGCGTGCATCACGGCTTCAAGCATGAAGACGTGTTCCTGTCGGC
CGGCGTGCAGTTGATGGTGCGCTCGGGCGTAGGCGCGGCAGGCGTGTTGTTCACGCTGGACACCGAATCCGGTTTCCGCG
ACGTGGTGTTCGTCACATCGAGCTTCGGCCTGGGCGAAATGGTCGTGCAGGGCGCGGTCAACCCGGACGAGTTCTATGTC
TACAAGCCCACGCTCACTGCAGGCAAGCCGGCGATCCTGCGCCGCTCGCTCGGCAGCAAGGCCATTCGCATGGTCTATTC
GGATGTGCCCGGCGAACGGGTGCGCACCGAAGACACGCCGGTGGAACTGCGCAGCACCTTTTCGATCAGCGACGAAGACG
TGCAGGAACTGTCCAAGCAGGCACTGGTGATCGAAAAGCATTACGGCCGCCCGATGGACATCGAGTGGGCCAAGGACGGG
GTCAGCGGCAAGCTGTTCATCGTGCAGGCGCGTCCGGAGACGGTGAAGTCGCGCAGTCATGCGACCCAGATCGAACGGTT
TGCGCTGGAAGCCAAGGGCGCCAAGATCCTGGCCGAAGGCCGCGCCGTCGGTGCCAAGATCGGTAGCGGCGTGGCACGCG
TGGTGCGCTCGCTGGACGACATGAATCGCGTCCAGGCTGGCGATGTGTTGATCGCGGACATGACCGACCCCGATTGGGAG
CCGGTGATGAAGCGCGCCTCTGCCATCGTCACCAACCGCGGCGGCCGCACCTGCCATGCAGCGATCATCGCGCGTGAGCT
CGGCGTGCCGGCGGTGGTGGGCTCGGGCAATGCCACCGACGTGCTCAGCGACGGCCAGGAAGTGACGGTCAGTTGCGCCG
AAGGCGACACCGGCTTCATCTACGATGGCCTGCTGCCGTTCGAGCGCACCACCACCGATCTGGGCAACATGCCGCCTGCC
CCGCTCAAGATCATGATGAACGTGGCAAACCCGGAGCGGGCCTTCGACTTCGGCCAGTTGCCCAATGCCGGCATTGGTCT
TGCGCGTCTTGAGATGATCATCGCCGCGCACATCGGCATCCACCCGAACGCGCTGCTGGAATACGACAAGCAGGACGCCG
ACGTCCTCAAGAAGATCGACGCCAAGATTGCCGGTTACGGCGATCCGGTGAGCTTCTACGTCAATCGCCTGGCCGAAGGT
ATCGCCACGCTGACCGCGTCGGTTGCGCCCAATACGGTGATCGTCCGTCTGTCGGACTTCAAGTCCAACGAATACGCCAA
CCTGATCGGCGGTTCGCGTTACGAGCCGCATGAAGAAAACCCGATGATCGGCTTCCGCGGCGCCAGCCGTTATGTCGATC
CCTCCTTCACCAAGGCGTTCGCGCTGGAGTGCAAGGCGGTGCTGAAGGTGCGTAACGAGATGGGCCTGGACAACCTCTGG
GTGATGATCCCGTTCGTGCGCACGCTGGAAGAAGGTCGCAAGGTGATCGAAGTGCTGGAGCAGAACGGGCTCAAGCAGGG
AGAGAACGGGCTGAAGATCATCATGATGTGCGAGCTGCCGTCCAACGCGCTGCTGGCCGACGAGTTCTTGGAGATCTTCG
ACGGCTTCTCGATCGGCTCCAACGACCTGACCCAGCTCACCCTGGGCCTGGATCGCGATTCGTCGATCGTCGCGCACCTG
TTCGACGAGCGGAACCCGGCGGTGAAGAAGCTGCTGTCGATGGCGATCAAGTCGGCGCGCGCCAAGGGCAAGTACGTGGG
TATCTGCGGCCAGGGGCCGTCCGACCACCCGGAGCTGGCCGAGTGGCTGATGCAGGAAGGAATCGAATCGGTGTCGTTGA
ATCCCGATACCGTGGTCGACACCTGGCTGCGTCTGGCCAAGCTCAAGAGCGAGGGCTGA

Upstream 100 bases:

>100_bases
ATGCTTGTGCAGGTTCCGCTGTGCACTGCATCATAGCGGCTTCTTCCTACGGTCGCGGCCATTCAGCCCGCTCGGGCGAT
GGCCTTACGGAGCATCGCGC

Downstream 100 bases:

>100_bases
TGGGACCGATGGGTGCAATGTGGGCGGCAGCTGCAGGAGCAGCTGCTGCAAAACCGGTTGCGGCAGCAGGAGCGGCAGCC
GCGAAGCCGGCCGCGACCAG

Product: phosphoenolpyruvate synthase

Products: NA

Alternate protein names: PEP synthase; Pyruvate, water dikinase [H]

Number of amino acids: Translated: 792; Mature: 792

Protein sequence:

>792_residues
MNENILWLHELRLADLARVGGKNSSLGEMIGNLAGLGVSVPGGYATTAEAFKDFIAHNDLSKRIFDRLATLDVEDVNALT
LAGKEIRGWVIDAPLQPDLDRDIRSAYAQLCAENGGGDVAVAVRSSATAEDLPDASFAGQQETFLNVTGADDVVHKVKEV
FASLYNDRAIAYRVHHGFKHEDVFLSAGVQLMVRSGVGAAGVLFTLDTESGFRDVVFVTSSFGLGEMVVQGAVNPDEFYV
YKPTLTAGKPAILRRSLGSKAIRMVYSDVPGERVRTEDTPVELRSTFSISDEDVQELSKQALVIEKHYGRPMDIEWAKDG
VSGKLFIVQARPETVKSRSHATQIERFALEAKGAKILAEGRAVGAKIGSGVARVVRSLDDMNRVQAGDVLIADMTDPDWE
PVMKRASAIVTNRGGRTCHAAIIARELGVPAVVGSGNATDVLSDGQEVTVSCAEGDTGFIYDGLLPFERTTTDLGNMPPA
PLKIMMNVANPERAFDFGQLPNAGIGLARLEMIIAAHIGIHPNALLEYDKQDADVLKKIDAKIAGYGDPVSFYVNRLAEG
IATLTASVAPNTVIVRLSDFKSNEYANLIGGSRYEPHEENPMIGFRGASRYVDPSFTKAFALECKAVLKVRNEMGLDNLW
VMIPFVRTLEEGRKVIEVLEQNGLKQGENGLKIIMMCELPSNALLADEFLEIFDGFSIGSNDLTQLTLGLDRDSSIVAHL
FDERNPAVKKLLSMAIKSARAKGKYVGICGQGPSDHPELAEWLMQEGIESVSLNPDTVVDTWLRLAKLKSEG

Sequences:

>Translated_792_residues
MNENILWLHELRLADLARVGGKNSSLGEMIGNLAGLGVSVPGGYATTAEAFKDFIAHNDLSKRIFDRLATLDVEDVNALT
LAGKEIRGWVIDAPLQPDLDRDIRSAYAQLCAENGGGDVAVAVRSSATAEDLPDASFAGQQETFLNVTGADDVVHKVKEV
FASLYNDRAIAYRVHHGFKHEDVFLSAGVQLMVRSGVGAAGVLFTLDTESGFRDVVFVTSSFGLGEMVVQGAVNPDEFYV
YKPTLTAGKPAILRRSLGSKAIRMVYSDVPGERVRTEDTPVELRSTFSISDEDVQELSKQALVIEKHYGRPMDIEWAKDG
VSGKLFIVQARPETVKSRSHATQIERFALEAKGAKILAEGRAVGAKIGSGVARVVRSLDDMNRVQAGDVLIADMTDPDWE
PVMKRASAIVTNRGGRTCHAAIIARELGVPAVVGSGNATDVLSDGQEVTVSCAEGDTGFIYDGLLPFERTTTDLGNMPPA
PLKIMMNVANPERAFDFGQLPNAGIGLARLEMIIAAHIGIHPNALLEYDKQDADVLKKIDAKIAGYGDPVSFYVNRLAEG
IATLTASVAPNTVIVRLSDFKSNEYANLIGGSRYEPHEENPMIGFRGASRYVDPSFTKAFALECKAVLKVRNEMGLDNLW
VMIPFVRTLEEGRKVIEVLEQNGLKQGENGLKIIMMCELPSNALLADEFLEIFDGFSIGSNDLTQLTLGLDRDSSIVAHL
FDERNPAVKKLLSMAIKSARAKGKYVGICGQGPSDHPELAEWLMQEGIESVSLNPDTVVDTWLRLAKLKSEG
>Mature_792_residues
MNENILWLHELRLADLARVGGKNSSLGEMIGNLAGLGVSVPGGYATTAEAFKDFIAHNDLSKRIFDRLATLDVEDVNALT
LAGKEIRGWVIDAPLQPDLDRDIRSAYAQLCAENGGGDVAVAVRSSATAEDLPDASFAGQQETFLNVTGADDVVHKVKEV
FASLYNDRAIAYRVHHGFKHEDVFLSAGVQLMVRSGVGAAGVLFTLDTESGFRDVVFVTSSFGLGEMVVQGAVNPDEFYV
YKPTLTAGKPAILRRSLGSKAIRMVYSDVPGERVRTEDTPVELRSTFSISDEDVQELSKQALVIEKHYGRPMDIEWAKDG
VSGKLFIVQARPETVKSRSHATQIERFALEAKGAKILAEGRAVGAKIGSGVARVVRSLDDMNRVQAGDVLIADMTDPDWE
PVMKRASAIVTNRGGRTCHAAIIARELGVPAVVGSGNATDVLSDGQEVTVSCAEGDTGFIYDGLLPFERTTTDLGNMPPA
PLKIMMNVANPERAFDFGQLPNAGIGLARLEMIIAAHIGIHPNALLEYDKQDADVLKKIDAKIAGYGDPVSFYVNRLAEG
IATLTASVAPNTVIVRLSDFKSNEYANLIGGSRYEPHEENPMIGFRGASRYVDPSFTKAFALECKAVLKVRNEMGLDNLW
VMIPFVRTLEEGRKVIEVLEQNGLKQGENGLKIIMMCELPSNALLADEFLEIFDGFSIGSNDLTQLTLGLDRDSSIVAHL
FDERNPAVKKLLSMAIKSARAKGKYVGICGQGPSDHPELAEWLMQEGIESVSLNPDTVVDTWLRLAKLKSEG

Specific function: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate [H]

COG id: COG0574

COG function: function code G; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PEP-utilizing enzyme family [H]

Homologues:

Organism=Escherichia coli, GI1787994, Length=787, Percent_Identity=64.8030495552732, Blast_Score=1073, Evalue=0.0,
Organism=Escherichia coli, GI1788756, Length=440, Percent_Identity=26.1363636363636, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI1788726, Length=189, Percent_Identity=33.3333333333333, Blast_Score=103, Evalue=5e-23,
Organism=Escherichia coli, GI48994992, Length=375, Percent_Identity=25.8666666666667, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1789193, Length=395, Percent_Identity=24.3037974683544, Blast_Score=89, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17564524, Length=483, Percent_Identity=25.2587991718427, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR008279
- InterPro:   IPR006319
- InterPro:   IPR018274
- InterPro:   IPR023151
- InterPro:   IPR000121
- InterPro:   IPR002192
- InterPro:   IPR015813 [H]

Pfam domain/function: PF00391 PEP-utilizers; PF02896 PEP-utilizers_C; PF01326 PPDK_N [H]

EC number: =2.7.9.2 [H]

Molecular weight: Translated: 85837; Mature: 85837

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00370 PEP_ENZYMES_PHOS_SITE ; PS00742 PEP_ENZYMES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNENILWLHELRLADLARVGGKNSSLGEMIGNLAGLGVSVPGGYATTAEAFKDFIAHNDL
CCCCEEEEEHHHHHHHHHHCCCCCHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHCCCH
SKRIFDRLATLDVEDVNALTLAGKEIRGWVIDAPLQPDLDRDIRSAYAQLCAENGGGDVA
HHHHHHHHHHCCCCCCCEEEECCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEE
VAVRSSATAEDLPDASFAGQQETFLNVTGADDVVHKVKEVFASLYNDRAIAYRVHHGFKH
EEEECCCCHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCC
EDVFLSAGVQLMVRSGVGAAGVLFTLDTESGFRDVVFVTSSFGLGEMVVQGAVNPDEFYV
CCEEHHCCHHHEEECCCCCCEEEEEEECCCCCCEEEEEECCCCHHHHHHHCCCCCCCEEE
YKPTLTAGKPAILRRSLGSKAIRMVYSDVPGERVRTEDTPVELRSTFSISDEDVQELSKQ
ECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEHEEECCCHHHHHHHHHH
ALVIEKHYGRPMDIEWAKDGVSGKLFIVQARPETVKSRSHATQIERFALEAKGAKILAEG
EEEEHHHCCCCCCCEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCEEEECC
RAVGAKIGSGVARVVRSLDDMNRVQAGDVLIADMTDPDWEPVMKRASAIVTNRGGRTCHA
CHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCHHH
AIIARELGVPAVVGSGNATDVLSDGQEVTVSCAEGDTGFIYDGLLPFERTTTDLGNMPPA
HHHHHHCCCCEEECCCCCCHHHCCCCEEEEEEECCCCCEEECCCCCCCCCCCCCCCCCCC
PLKIMMNVANPERAFDFGQLPNAGIGLARLEMIIAAHIGIHPNALLEYDKQDADVLKKID
CEEEEEECCCCHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHH
AKIAGYGDPVSFYVNRLAEGIATLTASVAPNTVIVRLSDFKSNEYANLIGGSRYEPHEEN
HHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHCCCCCCCCCCCC
PMIGFRGASRYVDPSFTKAFALECKAVLKVRNEMGLDNLWVMIPFVRTLEEGRKVIEVLE
CEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
QNGLKQGENGLKIIMMCELPSNALLADEFLEIFDGFSIGSNDLTQLTLGLDRDSSIVAHL
HCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHH
FDERNPAVKKLLSMAIKSARAKGKYVGICGQGPSDHPELAEWLMQEGIESVSLNPDTVVD
HHCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCHHHHH
TWLRLAKLKSEG
HHHHHHHHHCCC
>Mature Secondary Structure
MNENILWLHELRLADLARVGGKNSSLGEMIGNLAGLGVSVPGGYATTAEAFKDFIAHNDL
CCCCEEEEEHHHHHHHHHHCCCCCHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHCCCH
SKRIFDRLATLDVEDVNALTLAGKEIRGWVIDAPLQPDLDRDIRSAYAQLCAENGGGDVA
HHHHHHHHHHCCCCCCCEEEECCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEE
VAVRSSATAEDLPDASFAGQQETFLNVTGADDVVHKVKEVFASLYNDRAIAYRVHHGFKH
EEEECCCCHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCC
EDVFLSAGVQLMVRSGVGAAGVLFTLDTESGFRDVVFVTSSFGLGEMVVQGAVNPDEFYV
CCEEHHCCHHHEEECCCCCCEEEEEEECCCCCCEEEEEECCCCHHHHHHHCCCCCCCEEE
YKPTLTAGKPAILRRSLGSKAIRMVYSDVPGERVRTEDTPVELRSTFSISDEDVQELSKQ
ECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEHEEECCCHHHHHHHHHH
ALVIEKHYGRPMDIEWAKDGVSGKLFIVQARPETVKSRSHATQIERFALEAKGAKILAEG
EEEEHHHCCCCCCCEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCEEEECC
RAVGAKIGSGVARVVRSLDDMNRVQAGDVLIADMTDPDWEPVMKRASAIVTNRGGRTCHA
CHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCHHH
AIIARELGVPAVVGSGNATDVLSDGQEVTVSCAEGDTGFIYDGLLPFERTTTDLGNMPPA
HHHHHHCCCCEEECCCCCCHHHCCCCEEEEEEECCCCCEEECCCCCCCCCCCCCCCCCCC
PLKIMMNVANPERAFDFGQLPNAGIGLARLEMIIAAHIGIHPNALLEYDKQDADVLKKID
CEEEEEECCCCHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHH
AKIAGYGDPVSFYVNRLAEGIATLTASVAPNTVIVRLSDFKSNEYANLIGGSRYEPHEEN
HHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHCCCCCCCCCCCC
PMIGFRGASRYVDPSFTKAFALECKAVLKVRNEMGLDNLWVMIPFVRTLEEGRKVIEVLE
CEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
QNGLKQGENGLKIIMMCELPSNALLADEFLEIFDGFSIGSNDLTQLTLGLDRDSSIVAHL
HCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHH
FDERNPAVKKLLSMAIKSARAKGKYVGICGQGPSDHPELAEWLMQEGIESVSLNPDTVVD
HHCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCHHHHH
TWLRLAKLKSEG
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]