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The map label for this gene is trxB [H]

Identifier: 21242749

GI number: 21242749

Start: 2340636

End: 2341604

Strand: Reverse

Name: trxB [H]

Synonym: XAC2005

Alternate gene names: 21242749

Gene position: 2341604-2340636 (Counterclockwise)

Preceding gene: 77748626

Following gene: 21242748

Centisome position: 45.24

GC content: 65.63

Gene sequence:

>969_bases
ATGAGCGCCTCTTCTGCCAGCCCCGCCAAGCATTCCCGCCTGCTGATCCTGGGCTCCGGCCCGGCCGGCTGGACCGCCGC
GGTCTATGCCGCCCGCGCCAACCTCAAGCCGGTGGTCATCACCGGGTTGCAACAAGGCGGCCAGCTGATGACCACGACCG
AAGTGGACAACTGGCCGGGCGACCCCCATGGCCTGATGGGCCCGGACCTGATGAGCCGCATGCAGGCGCATGCCGAGCGC
TTCGAGACCGAGGTCATCTTCGACCATATCCACACGGCAGACCTGTCGCAACGCCCGTTCCGGCTGATCGGCGACGGTGC
CGAGTACACCTGCGACGCACTGATCATCGCCACCGGCGCCACCGCCAAGTACCTGGGCATCCCCACCGAAGAAGCCTTCA
AGGGCCGCGGCGTCTCCGCCTGCGCCACCTGCGACGGCTTCTTCTACAAGGACCAGGATGTGGTGGTGGTCGGCGGCGGC
AACACCGCGGTCGAAGAGGCGCTGTACCTGTCCAACATCGCCCGCAAGGTCTACCTGGTACATCGCCGCGACACCCTGCG
TGCGGAAAAGATCATGCAGGACAAGCTGTTCGCCAAGGTGGCCGCCGGCAAGATCGAGACCGTCTGGCACCATGCCATCG
ACGAAGTATTGGGCAACGATGCCGGGGTCACCGGCGTGAGGGTCAAGTCCACCATCGACGGCAGCACCCGCGATATCGAT
GCGCATGGTTTCTTCGTGGCGATCGGCCATCACCCGAATACGCAGTTGTTCGATGGCCAGCTGGCAATGAACAACGGCTA
CCTGGAGATTCGTTCCGGCCTGAACGGCGCGGCGACCGAAACCTCGGTGGCCGGCGTGTTCGCCGCCGGCGACGTGGCCG
ACCAGCATTACCGTCAGGCCATCACCTCGGCCGGCTTCGGCTGCATGGCCGCGCTGGATGCCGAACGCTTCCTCGACAAG
AGCGCCTGA

Upstream 100 bases:

>100_bases
CGCGCCGCCTTGATTCACCAGGTGGGGACCGCCACTCTATGCCGCCACGGGGACGCGAATGACTTCGCCTTCCCCACCAA
TTCCTAGATCGCGAGTATAC

Downstream 100 bases:

>100_bases
GATGGCGCCTGATTGCCGGCCGCGCCACGCGGCCAGCATCGCCAAAGGGCTGCCGGCATGGGCATAACCGCCCGCTGGTG
TCGCCAGCTGGACGAGTTGC

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MSASSASPAKHSRLLILGSGPAGWTAAVYAARANLKPVVITGLQQGGQLMTTTEVDNWPGDPHGLMGPDLMSRMQAHAER
FETEVIFDHIHTADLSQRPFRLIGDGAEYTCDALIIATGATAKYLGIPTEEAFKGRGVSACATCDGFFYKDQDVVVVGGG
NTAVEEALYLSNIARKVYLVHRRDTLRAEKIMQDKLFAKVAAGKIETVWHHAIDEVLGNDAGVTGVRVKSTIDGSTRDID
AHGFFVAIGHHPNTQLFDGQLAMNNGYLEIRSGLNGAATETSVAGVFAAGDVADQHYRQAITSAGFGCMAALDAERFLDK
SA

Sequences:

>Translated_322_residues
MSASSASPAKHSRLLILGSGPAGWTAAVYAARANLKPVVITGLQQGGQLMTTTEVDNWPGDPHGLMGPDLMSRMQAHAER
FETEVIFDHIHTADLSQRPFRLIGDGAEYTCDALIIATGATAKYLGIPTEEAFKGRGVSACATCDGFFYKDQDVVVVGGG
NTAVEEALYLSNIARKVYLVHRRDTLRAEKIMQDKLFAKVAAGKIETVWHHAIDEVLGNDAGVTGVRVKSTIDGSTRDID
AHGFFVAIGHHPNTQLFDGQLAMNNGYLEIRSGLNGAATETSVAGVFAAGDVADQHYRQAITSAGFGCMAALDAERFLDK
SA
>Mature_321_residues
SASSASPAKHSRLLILGSGPAGWTAAVYAARANLKPVVITGLQQGGQLMTTTEVDNWPGDPHGLMGPDLMSRMQAHAERF
ETEVIFDHIHTADLSQRPFRLIGDGAEYTCDALIIATGATAKYLGIPTEEAFKGRGVSACATCDGFFYKDQDVVVVGGGN
TAVEEALYLSNIARKVYLVHRRDTLRAEKIMQDKLFAKVAAGKIETVWHHAIDEVLGNDAGVTGVRVKSTIDGSTRDIDA
HGFFVAIGHHPNTQLFDGQLAMNNGYLEIRSGLNGAATETSVAGVFAAGDVADQHYRQAITSAGFGCMAALDAERFLDKS
A

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=311, Percent_Identity=67.524115755627, Blast_Score=446, Evalue=1e-127,
Organism=Escherichia coli, GI87081763, Length=323, Percent_Identity=31.5789473684211, Blast_Score=139, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6320560, Length=320, Percent_Identity=43.4375, Blast_Score=262, Evalue=7e-71,
Organism=Saccharomyces cerevisiae, GI6321898, Length=330, Percent_Identity=41.8181818181818, Blast_Score=251, Evalue=9e-68,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34324; Mature: 34193

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASSASPAKHSRLLILGSGPAGWTAAVYAARANLKPVVITGLQQGGQLMTTTEVDNWPG
CCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCCEEEEEEECCCCCC
DPHGLMGPDLMSRMQAHAERFETEVIFDHIHTADLSQRPFRLIGDGAEYTCDALIIATGA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEEEEEEECC
TAKYLGIPTEEAFKGRGVSACATCDGFFYKDQDVVVVGGGNTAVEEALYLSNIARKVYLV
CEEEECCCCHHHHCCCCCEEEEECCCCEECCCCEEEECCCCHHHHHHHHHHHHHHHEEEE
HRRDTLRAEKIMQDKLFAKVAAGKIETVWHHAIDEVLGNDAGVTGVRVKSTIDGSTRDID
ECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCEEC
AHGFFVAIGHHPNTQLFDGQLAMNNGYLEIRSGLNGAATETSVAGVFAAGDVADQHYRQA
CCEEEEEECCCCCCEEECCEEEECCCEEEEECCCCCCCCCHHHHEEEEECCHHHHHHHHH
ITSAGFGCMAALDAERFLDKSA
HHHCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SASSASPAKHSRLLILGSGPAGWTAAVYAARANLKPVVITGLQQGGQLMTTTEVDNWPG
CCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCCEEEEEEECCCCCC
DPHGLMGPDLMSRMQAHAERFETEVIFDHIHTADLSQRPFRLIGDGAEYTCDALIIATGA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEEEEEEECC
TAKYLGIPTEEAFKGRGVSACATCDGFFYKDQDVVVVGGGNTAVEEALYLSNIARKVYLV
CEEEECCCCHHHHCCCCCEEEEECCCCEECCCCEEEECCCCHHHHHHHHHHHHHHHEEEE
HRRDTLRAEKIMQDKLFAKVAAGKIETVWHHAIDEVLGNDAGVTGVRVKSTIDGSTRDID
ECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCEEC
AHGFFVAIGHHPNTQLFDGQLAMNNGYLEIRSGLNGAATETSVAGVFAAGDVADQHYRQA
CCEEEEEECCCCCCEEECCEEEECCCEEEEECCCCCCCCCHHHHEEEEECCHHHHHHHHH
ITSAGFGCMAALDAERFLDKSA
HHHCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]