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The map label for this gene is fabH [C]

Identifier: 21242708

GI number: 21242708

Start: 2296033

End: 2297034

Strand: Reverse

Name: fabH [C]

Synonym: XAC1964

Alternate gene names: 21242708

Gene position: 2297034-2296033 (Counterclockwise)

Preceding gene: 21242709

Following gene: 21242707

Centisome position: 44.38

GC content: 62.38

Gene sequence:

>1002_bases
ATGGCGACCTGCGTGCCCAAGCGCGTGGTGTCCAATCTCACCGATTGCCGCCCGCAAATCCGCACCGAGCGCGAGCGGCT
GGTGCGCAACATCGGCATCGAGACCCGCCGCATGGCCTCTGAATGGCAATGTTTTTCCGATCTGGCCTTCGACGCGACCG
AGGTGCTGCTGGAGCGTCTGCAGTGGAAGCGCGAGGAGATCGATGCACTGATCGTGGTGACGCAGTCGCCGGACTATCCG
ATTCCTGCCACCGCGATCATCCTGCAAGACAGGCTGGGGCTGTCGCATGCCACCGTCGCCTTCGACGTCAACCTGGGCTG
CTCGGCCTACCCGTTCGGCATCAACCTGCTCGGCTCGATGATCGCCGCCGGCGGCGTCAAGAAAGGCCTGCTACTGGTCG
GCGACCGTAGCGCGAACCTGGAAGACCCGATCTTCTCCGACTCGGGCACTGCCACCGCTTTGGAGTTCAGCGCCGACGCG
CCGCCGATGTATTTCGACCTCAATAGCGACGGCAGCGGCTATAAGGCAATCATCTTGCCGGTCGGCGGCCAACGCGAACC
GGTTGCCATACAGCATCTGATGCCGTTCCGCGAAGAACCCAACGGCCCGTGGCGACGCGGCACGGATCTGATCCTGGACG
GCGTGGCGGTGTTGAGCTTCTCCACTCAGCGCATTCCGCCAGCGGTACAGAAACTGCTCGACTACACCGGCGCTTCCAAG
GATGAGATCGACTACTTTGTGTTCCACCAAGCCAACCGCATGATCAACGAGACCATTCGCAAGAAACTCGGCCTGCCGGT
GGAAAAAGTGCCTTCGACGCTGCGCGACTTCGGCAACTCGAGCGGCGCCTCGCTGCCGGTGACCATGACCGCGCGCATCA
ACAAGGAGCTCGAATCCGGGTCCAAGCGCGTGTTGCTGTGCGGCTTCGGCATTGGCTTGTCGTGGGGCAGCTGTCTGCTC
GACATCGAAGGGGCCGTTTTTCCGGATCTGATCGAATCGTGA

Upstream 100 bases:

>100_bases
AAGATCTCAACGCTGCCATCACCGTCGGCGATCTCTACAAACTGACCGAGGCGTAAGCACCATGCCGACCTCCACGCTGC
ATAACGTCCGCTTTGCCGGT

Downstream 100 bases:

>100_bases
GTATCCCCCCCGACCCTTTCTCGCTTGCCGGCAAGCGCATCCTCGTCACTGGCGCATCCTCGGGTATTGGCCGCCAGATC
GCCATTTCCTGCGCCGAGCT

Product: 3-oxoacyl-[ACP] synthase

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MATCVPKRVVSNLTDCRPQIRTERERLVRNIGIETRRMASEWQCFSDLAFDATEVLLERLQWKREEIDALIVVTQSPDYP
IPATAIILQDRLGLSHATVAFDVNLGCSAYPFGINLLGSMIAAGGVKKGLLLVGDRSANLEDPIFSDSGTATALEFSADA
PPMYFDLNSDGSGYKAIILPVGGQREPVAIQHLMPFREEPNGPWRRGTDLILDGVAVLSFSTQRIPPAVQKLLDYTGASK
DEIDYFVFHQANRMINETIRKKLGLPVEKVPSTLRDFGNSSGASLPVTMTARINKELESGSKRVLLCGFGIGLSWGSCLL
DIEGAVFPDLIES

Sequences:

>Translated_333_residues
MATCVPKRVVSNLTDCRPQIRTERERLVRNIGIETRRMASEWQCFSDLAFDATEVLLERLQWKREEIDALIVVTQSPDYP
IPATAIILQDRLGLSHATVAFDVNLGCSAYPFGINLLGSMIAAGGVKKGLLLVGDRSANLEDPIFSDSGTATALEFSADA
PPMYFDLNSDGSGYKAIILPVGGQREPVAIQHLMPFREEPNGPWRRGTDLILDGVAVLSFSTQRIPPAVQKLLDYTGASK
DEIDYFVFHQANRMINETIRKKLGLPVEKVPSTLRDFGNSSGASLPVTMTARINKELESGSKRVLLCGFGIGLSWGSCLL
DIEGAVFPDLIES
>Mature_332_residues
ATCVPKRVVSNLTDCRPQIRTERERLVRNIGIETRRMASEWQCFSDLAFDATEVLLERLQWKREEIDALIVVTQSPDYPI
PATAIILQDRLGLSHATVAFDVNLGCSAYPFGINLLGSMIAAGGVKKGLLLVGDRSANLEDPIFSDSGTATALEFSADAP
PMYFDLNSDGSGYKAIILPVGGQREPVAIQHLMPFREEPNGPWRRGTDLILDGVAVLSFSTQRIPPAVQKLLDYTGASKD
EIDYFVFHQANRMINETIRKKLGLPVEKVPSTLRDFGNSSGASLPVTMTARINKELESGSKRVLLCGFGIGLSWGSCLLD
IEGAVFPDLIES

Specific function: May catalyze the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=323, Percent_Identity=26.625386996904, Blast_Score=115, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 36458; Mature: 36327

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATCVPKRVVSNLTDCRPQIRTERERLVRNIGIETRRMASEWQCFSDLAFDATEVLLERL
CCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QWKREEIDALIVVTQSPDYPIPATAIILQDRLGLSHATVAFDVNLGCSAYPFGINLLGSM
HHHHHCCCEEEEEECCCCCCCCCEEEEEEHHCCCCEEEEEEEECCCCCCCCCHHHHHHHH
IAAGGVKKGLLLVGDRSANLEDPIFSDSGTATALEFSADAPPMYFDLNSDGSGYKAIILP
HHHCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCEEEEEEE
VGGQREPVAIQHLMPFREEPNGPWRRGTDLILDGVAVLSFSTQRIPPAVQKLLDYTGASK
CCCCCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHEEECCCCCCHHHHHHHHHCCCCC
DEIDYFVFHQANRMINETIRKKLGLPVEKVPSTLRDFGNSSGASLPVTMTARINKELESG
CCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEEEEEHHHHHHHCC
SKRVLLCGFGIGLSWGSCLLDIEGAVFPDLIES
CCEEEEEEECCCCCCCCEEEEECCCCCHHHHCC
>Mature Secondary Structure 
ATCVPKRVVSNLTDCRPQIRTERERLVRNIGIETRRMASEWQCFSDLAFDATEVLLERL
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QWKREEIDALIVVTQSPDYPIPATAIILQDRLGLSHATVAFDVNLGCSAYPFGINLLGSM
HHHHHCCCEEEEEECCCCCCCCCEEEEEEHHCCCCEEEEEEEECCCCCCCCCHHHHHHHH
IAAGGVKKGLLLVGDRSANLEDPIFSDSGTATALEFSADAPPMYFDLNSDGSGYKAIILP
HHHCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCEEEEEEE
VGGQREPVAIQHLMPFREEPNGPWRRGTDLILDGVAVLSFSTQRIPPAVQKLLDYTGASK
CCCCCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHEEECCCCCCHHHHHHHHHCCCCC
DEIDYFVFHQANRMINETIRKKLGLPVEKVPSTLRDFGNSSGASLPVTMTARINKELESG
CCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEEEEEHHHHHHHCC
SKRVLLCGFGIGLSWGSCLLDIEGAVFPDLIES
CCEEEEEEECCCCCCCCEEEEECCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10688204 [H]