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The map label for this gene is fliM [H]

Identifier: 21242691

GI number: 21242691

Start: 2277843

End: 2278856

Strand: Reverse

Name: fliM [H]

Synonym: XAC1947

Alternate gene names: 21242691

Gene position: 2278856-2277843 (Counterclockwise)

Preceding gene: 21242692

Following gene: 21242690

Centisome position: 44.03

GC content: 64.4

Gene sequence:

>1014_bases
ATGAGCGTCAGTGATCTGCTTTCCCAGGACGAGATCGATGCCCTGCTGCACGGCGTGGATTCGGGCGCGGTCAACACCGA
GCCGGAGCCGCTGCCCGGCGAGGCGCGCCAATACGATCTGTCCAGCCAGGACCGCATCATCCGTGGGCGCATGCCGACCC
TGGAGATGGTCAACGAGCGCTTCGCGCGGTTGTGGCGGATCGGCCTGTTCAACCTGATCCGGCGCTCGGCCGACCTGTCG
GTGCGCGGCATCGACCTGGTCAAGTTCAACGAGTACATGCACTCGCTGTACGTGCCGACCAACCTCAACCTGATTCGGTT
CAAGCCGCTGCGCGGCACCGGCCTGATCGTGTTCGAACCCACCCTGGTGTTCACCGTGGTGGACAACTTCTTCGGTGGCG
ACGGCCGCTTCCACACCCGCATCGAAGGCCGCGAATTCACCGCCACCGAGATGCGCGTGATCCAGCTGATGCTCAAGCAG
ACCTTCGCCGACCTGAAGGAAGCCTGGGCGCCGGTGATGGACGTGGACTTCGAGTACATCAACTCGGAGATCAACCCGCA
CTTCGCCAACATCGTCACCCCGCGCGAGTACGTGGTGGTGTGCCGGTTCCATGTGGAGCTGGAAGGCGGCGGCGGCGAGA
TCCACATCACCCTGCCGTATTCGATGCTGGAGCCGATCCGCGAACTGCTCGATGCCGGCATCCAGAGCGACCGCAACGAC
CGCGACGACTCCTGGAACGTGATGCTGCGCGAGCAGCTGGACACCGCCGAGGTGACCCTGTCCAGCGTGCTGGCCAGCAA
GCGCATGAGCCTGCGCCAGCTCACCGGTTTGAAGGTCGGCGACATCCTGCCGATCGACCTGCCCGCCCAGGTGCCGCTGT
GCGTGGAAGACATCCCGTTATTCACCGGCGAATTCGGCGTTTCCAATGGCAACAACGCCGTCAAGATCACCGCCGTACGC
CCGCCCGGCGTGCAAGCCCCACGCGCCGTTCCCTCCCAGGACTCCAGCAAATGA

Upstream 100 bases:

>100_bases
GCCCTGGCCGAAGCGCAGAAGGTCATGACCAGCGAGACCGGCAAGAAGTGCGTCGAAGAATTGCTGTTCACCAGTTTCGT
GACCCAGTAAGGCCTGCCCG

Downstream 100 bases:

>100_bases
TCAACTCCGACACCCTCGACGCCTCGCCTGCCACCTTCGACAGCCTGCAGGCCGAGCAGGACCAGAACGCGGCCGACCTC
AACCTGGACGTGATCCTGGA

Product: flagellar motor switch protein FliM

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MSVSDLLSQDEIDALLHGVDSGAVNTEPEPLPGEARQYDLSSQDRIIRGRMPTLEMVNERFARLWRIGLFNLIRRSADLS
VRGIDLVKFNEYMHSLYVPTNLNLIRFKPLRGTGLIVFEPTLVFTVVDNFFGGDGRFHTRIEGREFTATEMRVIQLMLKQ
TFADLKEAWAPVMDVDFEYINSEINPHFANIVTPREYVVVCRFHVELEGGGGEIHITLPYSMLEPIRELLDAGIQSDRND
RDDSWNVMLREQLDTAEVTLSSVLASKRMSLRQLTGLKVGDILPIDLPAQVPLCVEDIPLFTGEFGVSNGNNAVKITAVR
PPGVQAPRAVPSQDSSK

Sequences:

>Translated_337_residues
MSVSDLLSQDEIDALLHGVDSGAVNTEPEPLPGEARQYDLSSQDRIIRGRMPTLEMVNERFARLWRIGLFNLIRRSADLS
VRGIDLVKFNEYMHSLYVPTNLNLIRFKPLRGTGLIVFEPTLVFTVVDNFFGGDGRFHTRIEGREFTATEMRVIQLMLKQ
TFADLKEAWAPVMDVDFEYINSEINPHFANIVTPREYVVVCRFHVELEGGGGEIHITLPYSMLEPIRELLDAGIQSDRND
RDDSWNVMLREQLDTAEVTLSSVLASKRMSLRQLTGLKVGDILPIDLPAQVPLCVEDIPLFTGEFGVSNGNNAVKITAVR
PPGVQAPRAVPSQDSSK
>Mature_336_residues
SVSDLLSQDEIDALLHGVDSGAVNTEPEPLPGEARQYDLSSQDRIIRGRMPTLEMVNERFARLWRIGLFNLIRRSADLSV
RGIDLVKFNEYMHSLYVPTNLNLIRFKPLRGTGLIVFEPTLVFTVVDNFFGGDGRFHTRIEGREFTATEMRVIQLMLKQT
FADLKEAWAPVMDVDFEYINSEINPHFANIVTPREYVVVCRFHVELEGGGGEIHITLPYSMLEPIRELLDAGIQSDRNDR
DDSWNVMLREQLDTAEVTLSSVLASKRMSLRQLTGLKVGDILPIDLPAQVPLCVEDIPLFTGEFGVSNGNNAVKITAVRP
PGVQAPRAVPSQDSSK

Specific function: FliM is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the mot

COG id: COG1868

COG function: function code N; Flagellar motor switch protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential). Bacterial flagellum basal body [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FliM family [H]

Homologues:

Organism=Escherichia coli, GI1788255, Length=315, Percent_Identity=46.031746031746, Blast_Score=271, Evalue=6e-74,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001689
- InterPro:   IPR001543 [H]

Pfam domain/function: PF02154 FliM; PF01052 SpoA [H]

EC number: NA

Molecular weight: Translated: 37824; Mature: 37693

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVSDLLSQDEIDALLHGVDSGAVNTEPEPLPGEARQYDLSSQDRIIRGRMPTLEMVNER
CCHHHHHCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHH
FARLWRIGLFNLIRRSADLSVRGIDLVKFNEYMHSLYVPTNLNLIRFKPLRGTGLIVFEP
HHHHHHHHHHHHHHHCCCCEEEEEEEEEHHHHHHHEECCCCCCEEEEECCCCCEEEEECC
TLVFTVVDNFFGGDGRFHTRIEGREFTATEMRVIQLMLKQTFADLKEAWAPVMDVDFEYI
CEEEEEHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHH
NSEINPHFANIVTPREYVVVCRFHVELEGGGGEIHITLPYSMLEPIRELLDAGIQSDRND
CCCCCCCHHEECCCCEEEEEEEEEEEEECCCCEEEEEECHHHHHHHHHHHHCCCCCCCCC
RDDSWNVMLREQLDTAEVTLSSVLASKRMSLRQLTGLKVGDILPIDLPAQVPLCVEDIPL
CCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCEEHHCCCC
FTGEFGVSNGNNAVKITAVRPPGVQAPRAVPSQDSSK
EECCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SVSDLLSQDEIDALLHGVDSGAVNTEPEPLPGEARQYDLSSQDRIIRGRMPTLEMVNER
CHHHHHCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHH
FARLWRIGLFNLIRRSADLSVRGIDLVKFNEYMHSLYVPTNLNLIRFKPLRGTGLIVFEP
HHHHHHHHHHHHHHHCCCCEEEEEEEEEHHHHHHHEECCCCCCEEEEECCCCCEEEEECC
TLVFTVVDNFFGGDGRFHTRIEGREFTATEMRVIQLMLKQTFADLKEAWAPVMDVDFEYI
CEEEEEHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHH
NSEINPHFANIVTPREYVVVCRFHVELEGGGGEIHITLPYSMLEPIRELLDAGIQSDRND
CCCCCCCHHEECCCCEEEEEEEEEEEEECCCCEEEEEECHHHHHHHHHHHHCCCCCCCCC
RDDSWNVMLREQLDTAEVTLSSVLASKRMSLRQLTGLKVGDILPIDLPAQVPLCVEDIPL
CCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCEEHHCCCC
FTGEFGVSNGNNAVKITAVRPPGVQAPRAVPSQDSSK
EECCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10984043; 7622217 [H]