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The map label for this gene is flhA [H]

Identifier: 21242680

GI number: 21242680

Start: 2262166

End: 2264259

Strand: Reverse

Name: flhA [H]

Synonym: XAC1936

Alternate gene names: 21242680

Gene position: 2264259-2262166 (Counterclockwise)

Preceding gene: 21242681

Following gene: 21242679

Centisome position: 43.75

GC content: 68.0

Gene sequence:

>2094_bases
ATGAGCGCCCGCCCAGCGCCGATGAATGCCCGCCGCGTCATGGAGTTGCTGCGCAACGGCCTGGGCGCCCCGCTGGCGTT
GATGGCCATGCTGGCCATGCTGATGGTGCCGCTGGCCGCGCCGGTGCTGGATGCGCTGTTCACCTTCAACATCGCCATCT
CGCTGATGGTGCTGCTGGCGGTGGTGTACGTGCAGCGCCCGCTGGAATTCACCATTTTCCCGATCGTGCTGTTGATGACC
ACGATGCTGCGGCTGGCGCTGAACGTCGCCTCCAGCCGCGTGATCCTGATCAACGGCCAGGACGGTCACGCCGCCGCCGG
CAAGGTCATCGAGGCCTTCGGCCAGTTCGTGATCGGCGGCAATTACGCCGTGGGTATCGTGGTCTTCGCGATCCTGACCA
TCATCAACTTCGTGGTCATCACCAAGGGTGCCGGACGCGTGTCGGAAGTGACCGCGCGCTTCATCCTGGACGCCATGCCC
GGCAAGCAGATGGCCATCGACGCCGACCTCAACGCCGGTTTGCTGACGCGCGAGGAGGCCAAGGCCCGCCGCGAGGAAGT
GCGCGAGGAAGCCGACTTCTACGGTGCGATGGACGGCGCCAACAAGTTCATCCGCGGCGACGCCATCGCCGCCATCCTGA
TCCTGTTCATCAACCTCATCGGCGGCATGGCGGTGGGCATGCTCCAGCACGGCATGAGCTTCATGGACGCCGCCTCCACC
TATACCCTGCTGTCGATCGGCGACGGCCTGGTGGCGCAGCTGCCGGCCTTGCTGGTCTCCTCGTCGGTCGCCTTGCTGGT
GACCCGCGCCTCGCGTGCGCAGGACATGCGCGGGGCCATGGTCAGCCAGGTGTTCGGCCAGCACCGCGCCTTGGCGGTGG
CTGCGGCCATCCTCGGGCTGGTCGGCCTGGTGCCGGGCATGCCGAACGTCGCGTTTTTGACGCTGGGCCTGGTCCTGGGC
GTGATCGCCTGGAAGCTGTACAAGCGCAGCCTGGCAAAACCGGCGTCCGGCGATCCGGCGGCCGATCCGCAGGCGGCCGC
CGCTGCGACCGCCGCCCAGGCCAGCGCCGAACTGAGCTGGGACGAACTGCGCCCGATCGACCCGCTGGGCCTGGAAGTGG
GCTATCGGCTGATCCCGCTGGTGGACAAGAACCAGGGCGGCGAGCTGATGGCGCGCATCAAGGGCGTGCGCCGCAAGCTC
ACCCAGGACATCGGTTTCCTGGTGCCGCCGGTGCACATCCGCGACAACCTGGAACTGTCGGCCAATGCCTACCGGCTACT
GGTGCATGGCGTGCCGGTGGCCACCGCAGAAATCTATTCCGACCGCGAACTGGCGCTGGACCCGGGCGGTGCGCTCGGCC
AGCTCGACGGCATCCCCGGCAAGGACCCGGCATTCGGCCTGGACGCCACCTGGATCCAGCCGCACCAGCGCGCCTATGCC
GAATCGATGGGCTACACCGTGGTCGACCCGGCGACCGTGGTCGCCACCCACCTGTCGCACCTGATCCGCGAGCATGCCCC
CGAACTGCTCGGCCACGAGGAGGTCCAGCAGTTGCTGGCGACCCTGGCCAAGACCGCGCCGAAGATGGTCGAAGACCTCA
CCCCGAAGGCGCTGCCGCTGTCGGTGGTGGTGCGCGTGCTGCAGAACCTGCTGATCGAGAAAATCCCGGTGCGGCAGTTG
CGCAAGATCGTCGAAGCGCTGGTCGAACACGCCCCGCATAGCCAGGACCCGGCCACCCTCACCGCCGCCGTGCGTACCTC
GCTGGGCCGCTTCATCGTGCAGGAAATCGCCGGCATGTCGGCCGAGCTGCCGGTGTTCACCCTGGCCCCGCAGCTGGAGC
GCGTCCTGCAGGAATCCACCCACGGCAACGGCGTGGCGCTGGAGCCCGGGCTGGCCGAACGCCTGCACCAAAGCCTGGCC
GATTGCGTGGGCAAGCAGGAAGCCCGCAACGAACCGGCGGTGGTGCTGGTCCCCGGGCAGGTGCGCGCCGCACTTGCCCG
CCTGGTCCGCCACAGCGTGCCCAGCCTATCGGTGCTGGCCTATAGCGAAGTCCCGGAAGACAAGCGCCTGAAGCTGGTGG
GCACGATCAGCTGA

Upstream 100 bases:

>100_bases
AGGTGCTCTCCTACGTCTACCAGCTGCGTGGCTGGAACGGCGGCCCGATGCCGGAACTGCCGTCGCTTGAGGTGGACGAG
TTCGGCAAGGGAGCCAGCGC

Downstream 100 bases:

>100_bases
GACCGCCCCGGCAACCACGCACCCGTCGCGCGCCGGGTTTGCCGGGGCCGCCCGTCGCGCCCGGGTGCGCTCCTACGACA
TTGAAGGCAATGCCGCCCAC

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 697; Mature: 696

Protein sequence:

>697_residues
MSARPAPMNARRVMELLRNGLGAPLALMAMLAMLMVPLAAPVLDALFTFNIAISLMVLLAVVYVQRPLEFTIFPIVLLMT
TMLRLALNVASSRVILINGQDGHAAAGKVIEAFGQFVIGGNYAVGIVVFAILTIINFVVITKGAGRVSEVTARFILDAMP
GKQMAIDADLNAGLLTREEAKARREEVREEADFYGAMDGANKFIRGDAIAAILILFINLIGGMAVGMLQHGMSFMDAAST
YTLLSIGDGLVAQLPALLVSSSVALLVTRASRAQDMRGAMVSQVFGQHRALAVAAAILGLVGLVPGMPNVAFLTLGLVLG
VIAWKLYKRSLAKPASGDPAADPQAAAAATAAQASAELSWDELRPIDPLGLEVGYRLIPLVDKNQGGELMARIKGVRRKL
TQDIGFLVPPVHIRDNLELSANAYRLLVHGVPVATAEIYSDRELALDPGGALGQLDGIPGKDPAFGLDATWIQPHQRAYA
ESMGYTVVDPATVVATHLSHLIREHAPELLGHEEVQQLLATLAKTAPKMVEDLTPKALPLSVVVRVLQNLLIEKIPVRQL
RKIVEALVEHAPHSQDPATLTAAVRTSLGRFIVQEIAGMSAELPVFTLAPQLERVLQESTHGNGVALEPGLAERLHQSLA
DCVGKQEARNEPAVVLVPGQVRAALARLVRHSVPSLSVLAYSEVPEDKRLKLVGTIS

Sequences:

>Translated_697_residues
MSARPAPMNARRVMELLRNGLGAPLALMAMLAMLMVPLAAPVLDALFTFNIAISLMVLLAVVYVQRPLEFTIFPIVLLMT
TMLRLALNVASSRVILINGQDGHAAAGKVIEAFGQFVIGGNYAVGIVVFAILTIINFVVITKGAGRVSEVTARFILDAMP
GKQMAIDADLNAGLLTREEAKARREEVREEADFYGAMDGANKFIRGDAIAAILILFINLIGGMAVGMLQHGMSFMDAAST
YTLLSIGDGLVAQLPALLVSSSVALLVTRASRAQDMRGAMVSQVFGQHRALAVAAAILGLVGLVPGMPNVAFLTLGLVLG
VIAWKLYKRSLAKPASGDPAADPQAAAAATAAQASAELSWDELRPIDPLGLEVGYRLIPLVDKNQGGELMARIKGVRRKL
TQDIGFLVPPVHIRDNLELSANAYRLLVHGVPVATAEIYSDRELALDPGGALGQLDGIPGKDPAFGLDATWIQPHQRAYA
ESMGYTVVDPATVVATHLSHLIREHAPELLGHEEVQQLLATLAKTAPKMVEDLTPKALPLSVVVRVLQNLLIEKIPVRQL
RKIVEALVEHAPHSQDPATLTAAVRTSLGRFIVQEIAGMSAELPVFTLAPQLERVLQESTHGNGVALEPGLAERLHQSLA
DCVGKQEARNEPAVVLVPGQVRAALARLVRHSVPSLSVLAYSEVPEDKRLKLVGTIS
>Mature_696_residues
SARPAPMNARRVMELLRNGLGAPLALMAMLAMLMVPLAAPVLDALFTFNIAISLMVLLAVVYVQRPLEFTIFPIVLLMTT
MLRLALNVASSRVILINGQDGHAAAGKVIEAFGQFVIGGNYAVGIVVFAILTIINFVVITKGAGRVSEVTARFILDAMPG
KQMAIDADLNAGLLTREEAKARREEVREEADFYGAMDGANKFIRGDAIAAILILFINLIGGMAVGMLQHGMSFMDAASTY
TLLSIGDGLVAQLPALLVSSSVALLVTRASRAQDMRGAMVSQVFGQHRALAVAAAILGLVGLVPGMPNVAFLTLGLVLGV
IAWKLYKRSLAKPASGDPAADPQAAAAATAAQASAELSWDELRPIDPLGLEVGYRLIPLVDKNQGGELMARIKGVRRKLT
QDIGFLVPPVHIRDNLELSANAYRLLVHGVPVATAEIYSDRELALDPGGALGQLDGIPGKDPAFGLDATWIQPHQRAYAE
SMGYTVVDPATVVATHLSHLIREHAPELLGHEEVQQLLATLAKTAPKMVEDLTPKALPLSVVVRVLQNLLIEKIPVRQLR
KIVEALVEHAPHSQDPATLTAAVRTSLGRFIVQEIAGMSAELPVFTLAPQLERVLQESTHGNGVALEPGLAERLHQSLAD
CVGKQEARNEPAVVLVPGQVRAALARLVRHSVPSLSVLAYSEVPEDKRLKLVGTIS

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=676, Percent_Identity=52.2189349112426, Blast_Score=669, Evalue=0.0,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 74339; Mature: 74208

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSARPAPMNARRVMELLRNGLGAPLALMAMLAMLMVPLAAPVLDALFTFNIAISLMVLLA
CCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVYVQRPLEFTIFPIVLLMTTMLRLALNVASSRVILINGQDGHAAAGKVIEAFGQFVIGG
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCEECC
NYAVGIVVFAILTIINFVVITKGAGRVSEVTARFILDAMPGKQMAIDADLNAGLLTREEA
CHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHH
KARREEVREEADFYGAMDGANKFIRGDAIAAILILFINLIGGMAVGMLQHGMSFMDAAST
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
YTLLSIGDGLVAQLPALLVSSSVALLVTRASRAQDMRGAMVSQVFGQHRALAVAAAILGL
EEHEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGLVPGMPNVAFLTLGLVLGVIAWKLYKRSLAKPASGDPAADPQAAAAATAAQASAELSW
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCH
DELRPIDPLGLEVGYRLIPLVDKNQGGELMARIKGVRRKLTQDIGFLVPPVHIRDNLELS
HHCCCCCCCCHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCEEC
ANAYRLLVHGVPVATAEIYSDRELALDPGGALGQLDGIPGKDPAFGLDATWIQPHQRAYA
CCCEEEEEECCCHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
ESMGYTVVDPATVVATHLSHLIREHAPELLGHEEVQQLLATLAKTAPKMVEDLTPKALPL
HHCCCEEECHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
SVVVRVLQNLLIEKIPVRQLRKIVEALVEHAPHSQDPATLTAAVRTSLGRFIVQEIAGMS
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
AELPVFTLAPQLERVLQESTHGNGVALEPGLAERLHQSLADCVGKQEARNEPAVVLVPGQ
CCCCHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHCHHHHCCCCEEEEECCH
VRAALARLVRHSVPSLSVLAYSEVPEDKRLKLVGTIS
HHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEECC
>Mature Secondary Structure 
SARPAPMNARRVMELLRNGLGAPLALMAMLAMLMVPLAAPVLDALFTFNIAISLMVLLA
CCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVYVQRPLEFTIFPIVLLMTTMLRLALNVASSRVILINGQDGHAAAGKVIEAFGQFVIGG
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCEECC
NYAVGIVVFAILTIINFVVITKGAGRVSEVTARFILDAMPGKQMAIDADLNAGLLTREEA
CHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHH
KARREEVREEADFYGAMDGANKFIRGDAIAAILILFINLIGGMAVGMLQHGMSFMDAAST
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
YTLLSIGDGLVAQLPALLVSSSVALLVTRASRAQDMRGAMVSQVFGQHRALAVAAAILGL
EEHEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGLVPGMPNVAFLTLGLVLGVIAWKLYKRSLAKPASGDPAADPQAAAAATAAQASAELSW
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCH
DELRPIDPLGLEVGYRLIPLVDKNQGGELMARIKGVRRKLTQDIGFLVPPVHIRDNLELS
HHCCCCCCCCHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCEEC
ANAYRLLVHGVPVATAEIYSDRELALDPGGALGQLDGIPGKDPAFGLDATWIQPHQRAYA
CCCEEEEEECCCHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
ESMGYTVVDPATVVATHLSHLIREHAPELLGHEEVQQLLATLAKTAPKMVEDLTPKALPL
HHCCCEEECHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
SVVVRVLQNLLIEKIPVRQLRKIVEALVEHAPHSQDPATLTAAVRTSLGRFIVQEIAGMS
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
AELPVFTLAPQLERVLQESTHGNGVALEPGLAERLHQSLADCVGKQEARNEPAVVLVPGQ
CCCCHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHCHHHHCCCCEEEEECCH
VRAALARLVRHSVPSLSVLAYSEVPEDKRLKLVGTIS
HHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]