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The map label for this gene is cheA [H]

Identifier: 21242647

GI number: 21242647

Start: 2226399

End: 2228405

Strand: Reverse

Name: cheA [H]

Synonym: XAC1903

Alternate gene names: 21242647

Gene position: 2228405-2226399 (Counterclockwise)

Preceding gene: 21242648

Following gene: 21242646

Centisome position: 43.06

GC content: 66.32

Gene sequence:

>2007_bases
ATGAGCATGGACCTGCAACGTTTCCACGCCACCTTTTTCGAGGAAAGCCGTGAAGGGCTCGACGCGATGGAGGCTGGGCT
GCTGTCGCTTGAAGAAGGCAACCGCGACCCGGAAATCATCAACTCGGTGTTCCGCGCCGCGCACTCGATCAAGGGCGGCG
CCGCCACCTTCGGCTTCGACGCCGTCGCCGGCCTGACCCACGTGCTGGAGACGCTGCTGGACGAGCTGCGCTCCAACAAG
CGCCAGCTCGAACCCAATGCGGTCGATGCCATGCTTGGCTCGGTCGACGTGCTGCGCGCCCTGTTGCGCGAAGCCGAACA
CGGCACCCCGGCCGACCCGGCTGCGGTCAAGGCCGTGCACACCCGGTTGAATGCCGTGCTTGCTGGCGAAGCGCCGGCGG
CCGCAGCGGTCGCCAAGCCGAAGGAAGAAGAACCCGAAGCCTGGCACATCGGTTTCACCCCGGCGCCGTCGCTGTTCATG
AGCGGCAACGACCCGTTGCGCATCATCCGCGAGCTCGAACACCTGGGCCCGCTGCAGATCGCCGCGCGTCTGGAGCGCAT
GCCGGGCTTTGAGAACATCGACCCGCTGGAAGCGTATCTGGCGTGGGACCTGGGCCTGATCGGCAAGATTCCGCGCAGCA
AGATCGAAGACACCTTCGCCTGGGTGGTGGACGATTGCGAGCTGGACATCCGCCCAATGGCGGTGCCCGGCCCGCCGCCG
AGCCTGGCCGTGGACGCTCCGGGTGCCGCACCGGTTGCAGCGGTCGCTGCCGCACCGAGTGCCGTTGCCGAACCTGCCGC
CGCGGCGACACCGGCCAAGGCCGCCGCTGCCGAAGCTGAAAGCTCGATCCGCGTCAGCGTCGACAAGGTCGATGCATTGA
TCAACCTGGTCGGCGAGCTGGTGATTACCCAGGCCATGCTCAAGCAGGTCTCCACCGGTCTGGACCCAGCGCATGCCGAA
CAACTGTTCGCCGGCCTGGATCTGCTCGAACGCAATACCCGCGATCTGCAGGAAGCGGTCATCGGCGTGCGCATGCTGCC
CGTCGATGCGGTGTTCCGCCGCTTCCCGCGCCTGGTGCGCGACCTCTCCAGCCGCCTCGGCAAGCAGGTGCGCCTGCGCA
CCATTGGCGAAAGTACCGAGTTGGACAAGGGGTTGATCGAGAAGATTGCCGATCCGTTGGTGCACCTGGTGCGCAACTCG
ATCGACCATGGCCTGGAAATGCCCGATGCGCGCCGCGCCTCCGGCAAGGACGAAACCGGCACGATTACCCTGGCGGCCTC
GCACCAGGGCGGCCACATCGTGATCGAAGTCAGCGACGACGGCCGTGGCCTCAATCGCGCCAAGATCCTGGAAAAAGCGG
CCGAGCGCGGCATCGCCGTGCCGGACAACCCGACCGATGCGCAGGTGTGGGACTTGATCTTCGCACCGGGCTTCTCCACC
GCCGATGCGGTGACCGACCTGTCCGGTCGTGGCGTGGGCATGGACGTGGTCCGCCGCAACATCCAGGGCCTGGGTGGCGA
AGTGCAGCTGGAAAGCAATGCCGGCAGCGGCACCCGCGTGTTGATCCGTCTGCCGCTGACCCTGGCCATCCTGGACGGCA
TGACCGTGTCGGTCGCCGGCGAAACCCTGATCCTGCCGCTGTCCTACGTGCTCGAAGCCCTGCAGCCGGCACCAGAAGAC
GTCCGTGCGATGGCCGGCGACGGTCGGGTACTGCGGGTGCGTGGCGAATATCTGCCGATCCTCTCGCTCACCAACTACTA
CGGCTTCGGCGGGCAGCAGTCCTCCAAGGAATCGCTGGTGGTGGTGGTCGAAGGCGACGGCCAGAAGATCGCGCTGGAAG
TGGACGAGTTGCTCGGCCAGCAGCAGGTGGTGGTCAAGAACATCGAGAACAATTACCGGCGCATTCCGGGCGTTTCCGGC
GCCACCATCCTCGGCGATGGGCGGGTTTCGCTGATCGTGGACATCGGCGGTCTGGTGCGCTCGCTCAAGGTGCCGCAAGC
CGCGTAA

Upstream 100 bases:

>100_bases
CGGTTGGCTGGTCAAGCCGTTCAATCCAGAACAGCTGATCGCCACCGTCCAGAAAGTTCTCGGTTAAACCCTTCTCGCTT
CAGCTTCGGATTTCACGCCC

Downstream 100 bases:

>100_bases
TGCAGTCGCCGCGGCGTGGATGCCGCGGCGCAAGACTCCGCCACGCCATCGACGCACGATGGTTGCTGGAGCGATCGCCG
GCAGTATGGGGACTGCCGGC

Product: chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 668; Mature: 667

Protein sequence:

>668_residues
MSMDLQRFHATFFEESREGLDAMEAGLLSLEEGNRDPEIINSVFRAAHSIKGGAATFGFDAVAGLTHVLETLLDELRSNK
RQLEPNAVDAMLGSVDVLRALLREAEHGTPADPAAVKAVHTRLNAVLAGEAPAAAAVAKPKEEEPEAWHIGFTPAPSLFM
SGNDPLRIIRELEHLGPLQIAARLERMPGFENIDPLEAYLAWDLGLIGKIPRSKIEDTFAWVVDDCELDIRPMAVPGPPP
SLAVDAPGAAPVAAVAAAPSAVAEPAAAATPAKAAAAEAESSIRVSVDKVDALINLVGELVITQAMLKQVSTGLDPAHAE
QLFAGLDLLERNTRDLQEAVIGVRMLPVDAVFRRFPRLVRDLSSRLGKQVRLRTIGESTELDKGLIEKIADPLVHLVRNS
IDHGLEMPDARRASGKDETGTITLAASHQGGHIVIEVSDDGRGLNRAKILEKAAERGIAVPDNPTDAQVWDLIFAPGFST
ADAVTDLSGRGVGMDVVRRNIQGLGGEVQLESNAGSGTRVLIRLPLTLAILDGMTVSVAGETLILPLSYVLEALQPAPED
VRAMAGDGRVLRVRGEYLPILSLTNYYGFGGQQSSKESLVVVVEGDGQKIALEVDELLGQQQVVVKNIENNYRRIPGVSG
ATILGDGRVSLIVDIGGLVRSLKVPQAA

Sequences:

>Translated_668_residues
MSMDLQRFHATFFEESREGLDAMEAGLLSLEEGNRDPEIINSVFRAAHSIKGGAATFGFDAVAGLTHVLETLLDELRSNK
RQLEPNAVDAMLGSVDVLRALLREAEHGTPADPAAVKAVHTRLNAVLAGEAPAAAAVAKPKEEEPEAWHIGFTPAPSLFM
SGNDPLRIIRELEHLGPLQIAARLERMPGFENIDPLEAYLAWDLGLIGKIPRSKIEDTFAWVVDDCELDIRPMAVPGPPP
SLAVDAPGAAPVAAVAAAPSAVAEPAAAATPAKAAAAEAESSIRVSVDKVDALINLVGELVITQAMLKQVSTGLDPAHAE
QLFAGLDLLERNTRDLQEAVIGVRMLPVDAVFRRFPRLVRDLSSRLGKQVRLRTIGESTELDKGLIEKIADPLVHLVRNS
IDHGLEMPDARRASGKDETGTITLAASHQGGHIVIEVSDDGRGLNRAKILEKAAERGIAVPDNPTDAQVWDLIFAPGFST
ADAVTDLSGRGVGMDVVRRNIQGLGGEVQLESNAGSGTRVLIRLPLTLAILDGMTVSVAGETLILPLSYVLEALQPAPED
VRAMAGDGRVLRVRGEYLPILSLTNYYGFGGQQSSKESLVVVVEGDGQKIALEVDELLGQQQVVVKNIENNYRRIPGVSG
ATILGDGRVSLIVDIGGLVRSLKVPQAA
>Mature_667_residues
SMDLQRFHATFFEESREGLDAMEAGLLSLEEGNRDPEIINSVFRAAHSIKGGAATFGFDAVAGLTHVLETLLDELRSNKR
QLEPNAVDAMLGSVDVLRALLREAEHGTPADPAAVKAVHTRLNAVLAGEAPAAAAVAKPKEEEPEAWHIGFTPAPSLFMS
GNDPLRIIRELEHLGPLQIAARLERMPGFENIDPLEAYLAWDLGLIGKIPRSKIEDTFAWVVDDCELDIRPMAVPGPPPS
LAVDAPGAAPVAAVAAAPSAVAEPAAAATPAKAAAAEAESSIRVSVDKVDALINLVGELVITQAMLKQVSTGLDPAHAEQ
LFAGLDLLERNTRDLQEAVIGVRMLPVDAVFRRFPRLVRDLSSRLGKQVRLRTIGESTELDKGLIEKIADPLVHLVRNSI
DHGLEMPDARRASGKDETGTITLAASHQGGHIVIEVSDDGRGLNRAKILEKAAERGIAVPDNPTDAQVWDLIFAPGFSTA
DAVTDLSGRGVGMDVVRRNIQGLGGEVQLESNAGSGTRVLIRLPLTLAILDGMTVSVAGETLILPLSYVLEALQPAPEDV
RAMAGDGRVLRVRGEYLPILSLTNYYGFGGQQSSKESLVVVVEGDGQKIALEVDELLGQQQVVVKNIENNYRRIPGVSGA
TILGDGRVSLIVDIGGLVRSLKVPQAA

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=668, Percent_Identity=45.8083832335329, Blast_Score=543, Evalue=1e-155,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR015162
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF09078 CheY-binding; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 71085; Mature: 70954

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMDLQRFHATFFEESREGLDAMEAGLLSLEEGNRDPEIINSVFRAAHSIKGGAATFGFD
CCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCHH
AVAGLTHVLETLLDELRSNKRQLEPNAVDAMLGSVDVLRALLREAEHGTPADPAAVKAVH
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHH
TRLNAVLAGEAPAAAAVAKPKEEEPEAWHIGFTPAPSLFMSGNDPLRIIRELEHLGPLQI
HHHHHHEECCCCCHHHHCCCCCCCCCEEEECCCCCCCEEECCCCHHHHHHHHHHCCHHHH
AARLERMPGFENIDPLEAYLAWDLGLIGKIPRSKIEDTFAWVVDDCELDIRPMAVPGPPP
HHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHEEEECCCCCEEEEECCCCCC
SLAVDAPGAAPVAAVAAAPSAVAEPAAAATPAKAAAAEAESSIRVSVDKVDALINLVGEL
CCEECCCCCCHHHHHHCCCHHHCCCCHHCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHH
VITQAMLKQVSTGLDPAHAEQLFAGLDLLERNTRDLQEAVIGVRMLPVDAVFRRFPRLVR
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
DLSSRLGKQVRLRTIGESTELDKGLIEKIADPLVHLVRNSIDHGLEMPDARRASGKDETG
HHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
TITLAASHQGGHIVIEVSDDGRGLNRAKILEKAAERGIAVPDNPTDAQVWDLIFAPGFST
EEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHEEECCCCCC
ADAVTDLSGRGVGMDVVRRNIQGLGGEVQLESNAGSGTRVLIRLPLTLAILDGMTVSVAG
HHHHHCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCHHHHHHCCCEEEECC
ETLILPLSYVLEALQPAPEDVRAMAGDGRVLRVRGEYLPILSLTNYYGFGGQQSSKESLV
CEEEEEHHHHHHHHCCCCHHHHHHCCCCCEEEECCCEECEEEECCCCCCCCCCCCCCCEE
VVVEGDGQKIALEVDELLGQQQVVVKNIENNYRRIPGVSGATILGDGRVSLIVDIGGLVR
EEEECCCCEEEEEHHHHCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEEHHHHHH
SLKVPQAA
HCCCCCCC
>Mature Secondary Structure 
SMDLQRFHATFFEESREGLDAMEAGLLSLEEGNRDPEIINSVFRAAHSIKGGAATFGFD
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCHH
AVAGLTHVLETLLDELRSNKRQLEPNAVDAMLGSVDVLRALLREAEHGTPADPAAVKAVH
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHH
TRLNAVLAGEAPAAAAVAKPKEEEPEAWHIGFTPAPSLFMSGNDPLRIIRELEHLGPLQI
HHHHHHEECCCCCHHHHCCCCCCCCCEEEECCCCCCCEEECCCCHHHHHHHHHHCCHHHH
AARLERMPGFENIDPLEAYLAWDLGLIGKIPRSKIEDTFAWVVDDCELDIRPMAVPGPPP
HHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHEEEECCCCCEEEEECCCCCC
SLAVDAPGAAPVAAVAAAPSAVAEPAAAATPAKAAAAEAESSIRVSVDKVDALINLVGEL
CCEECCCCCCHHHHHHCCCHHHCCCCHHCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHH
VITQAMLKQVSTGLDPAHAEQLFAGLDLLERNTRDLQEAVIGVRMLPVDAVFRRFPRLVR
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
DLSSRLGKQVRLRTIGESTELDKGLIEKIADPLVHLVRNSIDHGLEMPDARRASGKDETG
HHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
TITLAASHQGGHIVIEVSDDGRGLNRAKILEKAAERGIAVPDNPTDAQVWDLIFAPGFST
EEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHEEECCCCCC
ADAVTDLSGRGVGMDVVRRNIQGLGGEVQLESNAGSGTRVLIRLPLTLAILDGMTVSVAG
HHHHHCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCHHHHHHCCCEEEECC
ETLILPLSYVLEALQPAPEDVRAMAGDGRVLRVRGEYLPILSLTNYYGFGGQQSSKESLV
CEEEEEHHHHHHHHCCCCHHHHHHCCCCCEEEECCCEECEEEECCCCCCCCCCCCCCCEE
VVVEGDGQKIALEVDELLGQQQVVVKNIENNYRRIPGVSGATILGDGRVSLIVDIGGLVR
EEEECCCCEEEEEHHHHCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEEHHHHHH
SLKVPQAA
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2002011; 9097040; 9278503; 3510184; 2832069; 2068106; 8555213; 8639521; 9020767; 9437425; 9636149 [H]