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The map label for this gene is hmsH [H]

Identifier: 21242557

GI number: 21242557

Start: 2087115

End: 2089157

Strand: Reverse

Name: hmsH [H]

Synonym: XAC1813

Alternate gene names: 21242557

Gene position: 2089157-2087115 (Counterclockwise)

Preceding gene: 21242566

Following gene: 21242556

Centisome position: 40.37

GC content: 65.83

Gene sequence:

>2043_bases
TTGTTCACCGCATGTGTGCCACAGGCGCACAGCGGCGAAGTGCGGTCTGCGGACGTGTCTGGTGCCTCCACTGCCCTCAC
CCCCATGCAGCAGGCCGAGCAATTTCGCGGCCGGCAACGCTACGCGGACGCCTTGGCCATCTACGAGCGGGTCTTGCATG
CCGACCCACGCGATAGAGGCGCCTACACGATGCGCGCGCTCACGCTCAGCGACCTCGGCAGCGCGCAACTCGCGGCCGAG
GCGATGTGGCGGCATCCGAACTGGTTTTCGCAGCAGGAACGCGAGCGCCTGGATAACGACCGCGTCGCACGCATGATCGG
CTGGGCCAGCGCCGAGCCGGTGGATGCTACGCATCGCTATGCCGAGACCGATCAGGCGCTGGCCAATGCAGCCCGCATCC
AGCGCGACGCGCCTCCACAGGCTGCCTGGGAAGCGACACGATTGCGCGTGGACAGCCTGGTCGCGCTCAATCAACGCCAG
CGGCACCGCGATGTGATCGCCAACTATCAGGCGCTGCGTGCCGAAGGCGTCGATGTGCCGGCATACGTGCTGCCGACGGT
GGGCGATTCGCTGATGGGGCTGCGCCGCCCTGCCGAAGCGGAAAGCGTGCTTCGTCAAGCATTGCAGCACTCACCGAACG
ACTTCAATACGCAATTGCTGCTGGGCTACGCATTGCTGGAGCAGGAACGCTTCGACGAAGCAATGCCGCTATTCGAATCC
CTGGCCGCCACGCAAGCCCCATGGCCGCGCCGGGAAGGTGCCACCAGCGGTTACGAAAACTGGGACCGCTTCAGCGCCGA
TATCGCGCTGGCTACCGCACGTTCTGCGGCCAACGATAATCGCGGTGCGGAGGCATTGCTGCGCGAGCGTGCGGCCATTG
GCCCGGATAATGCCGAGCTACAAGCGGCACTGGCATCGATCGAAGCGCGTCGCGGCCAGACCATGCAGGCACTGCAGCGC
AATCGGATGGCGTTGACGCTGGATCCGCATCAGAAACAGGCGCGCAGCGGCGTGGTGGAAGCGCAACGCGATCTTGATCG
CCTGGATCTTGCGGATGCCGCGTTCGCGTCGCTGCAACAGGAGTATCCGGACGACGCCGGCCTGCAACGGCTTGGCGCAT
CGCTGGAACGTCAACGAGGCTGGCAGGTGCACCTGAGCCATGCCTGGGGACGCAGCGAGAATGACACGCTGACCAACAGC
ACCTCGCCGCTCGGCAATCACTTCGGCAGTTCGCTGCTGGAAGCCGAATCGCCGTTACTCGGCGAGCGTTGGCGGGTGGG
CCTGCGCGCGCGCGATGACTGGGCGGATTTCCAGGCCACCCGCGTGCGTTACCGCAGCTTCTGGCTGGGTGCGCATTACC
GCTACGACCGCCTGGATTTCAGCGCGTACGGCGGCCGCGCCCTGGATGATTTCGATCGCGACGGCACTGCCTGGGCGCTG
GATGCCGGCTGGCGCTTTTCCGATGCGTGGTATGGCAGCGTCGCCTGGCGCACACGCGACCCGGAGGCCTCGCTGCAGGC
GCGCCGCCTGGGCATCACCGGCGACAGCATCGGTGCTGCCGTGCGCTGGACGCCCAGCGACGAAAGCCGGTGGGAACTGC
AGGCACGCCAGTTGCGTTATAGCGACGGCAATCGACGCGATCAGCTGGATCTTTTCGGTAGCCAACGCCTGTGGGCCAAC
CCGCATGTCCTGGTCGATGGGCTGTTCGCCGCCTCGGCCGGGCGCGCCGAAGACGACCGCGCGGTCGATTACTTCAATCC
ACGCCATAGCTCTGCAGTTGCCGCCGGCGTACGGATCGAACAGATCGGCTGGCGCCGGTACGACGACGCGTTTCGGCAGC
GATTGGAAGTGACTGCCGGGCCGACCTACCAGTCCGGCTTCGGCAGCCGCTGGGTACCTGCGCTTGCCTATCGCCATCTG
TGGTCGCTGGGCGATGGCAGCGCATTGAGCTACGGCGTGAGTTGGTCGCGCCCGGTCTACGACGGCCAGCGCGAACAACA
ACTTGGATTGGACCTTGATTTCCGATGGGGAGGTACGCCGTGA

Upstream 100 bases:

>100_bases
GGATCGCTCGTGAATCTCCCCCTCCCCCTGTTCACGCAATCACGTGCAGCGCGGTCGTCCTGACCGTACAGGCGCACTCA
CTCCTCTGCTCAGCCTCGCT

Downstream 100 bases:

>100_bases
TCCGCCTGCCGCTGCTGCTGGTCGCATTGTTGCTGATGACGTTTGCCTCGTCGGCGCAGGCGGGCCTGCTCGTGCTCAGC
TACCACGATATTCGCGACGA

Product: HmsH protein

Products: NA

Alternate protein names: PGA export protein; Poly-beta-1,6-GlcNAc export protein [H]

Number of amino acids: Translated: 680; Mature: 680

Protein sequence:

>680_residues
MFTACVPQAHSGEVRSADVSGASTALTPMQQAEQFRGRQRYADALAIYERVLHADPRDRGAYTMRALTLSDLGSAQLAAE
AMWRHPNWFSQQERERLDNDRVARMIGWASAEPVDATHRYAETDQALANAARIQRDAPPQAAWEATRLRVDSLVALNQRQ
RHRDVIANYQALRAEGVDVPAYVLPTVGDSLMGLRRPAEAESVLRQALQHSPNDFNTQLLLGYALLEQERFDEAMPLFES
LAATQAPWPRREGATSGYENWDRFSADIALATARSAANDNRGAEALLRERAAIGPDNAELQAALASIEARRGQTMQALQR
NRMALTLDPHQKQARSGVVEAQRDLDRLDLADAAFASLQQEYPDDAGLQRLGASLERQRGWQVHLSHAWGRSENDTLTNS
TSPLGNHFGSSLLEAESPLLGERWRVGLRARDDWADFQATRVRYRSFWLGAHYRYDRLDFSAYGGRALDDFDRDGTAWAL
DAGWRFSDAWYGSVAWRTRDPEASLQARRLGITGDSIGAAVRWTPSDESRWELQARQLRYSDGNRRDQLDLFGSQRLWAN
PHVLVDGLFAASAGRAEDDRAVDYFNPRHSSAVAAGVRIEQIGWRRYDDAFRQRLEVTAGPTYQSGFGSRWVPALAYRHL
WSLGDGSALSYGVSWSRPVYDGQREQQLGLDLDFRWGGTP

Sequences:

>Translated_680_residues
MFTACVPQAHSGEVRSADVSGASTALTPMQQAEQFRGRQRYADALAIYERVLHADPRDRGAYTMRALTLSDLGSAQLAAE
AMWRHPNWFSQQERERLDNDRVARMIGWASAEPVDATHRYAETDQALANAARIQRDAPPQAAWEATRLRVDSLVALNQRQ
RHRDVIANYQALRAEGVDVPAYVLPTVGDSLMGLRRPAEAESVLRQALQHSPNDFNTQLLLGYALLEQERFDEAMPLFES
LAATQAPWPRREGATSGYENWDRFSADIALATARSAANDNRGAEALLRERAAIGPDNAELQAALASIEARRGQTMQALQR
NRMALTLDPHQKQARSGVVEAQRDLDRLDLADAAFASLQQEYPDDAGLQRLGASLERQRGWQVHLSHAWGRSENDTLTNS
TSPLGNHFGSSLLEAESPLLGERWRVGLRARDDWADFQATRVRYRSFWLGAHYRYDRLDFSAYGGRALDDFDRDGTAWAL
DAGWRFSDAWYGSVAWRTRDPEASLQARRLGITGDSIGAAVRWTPSDESRWELQARQLRYSDGNRRDQLDLFGSQRLWAN
PHVLVDGLFAASAGRAEDDRAVDYFNPRHSSAVAAGVRIEQIGWRRYDDAFRQRLEVTAGPTYQSGFGSRWVPALAYRHL
WSLGDGSALSYGVSWSRPVYDGQREQQLGLDLDFRWGGTP
>Mature_680_residues
MFTACVPQAHSGEVRSADVSGASTALTPMQQAEQFRGRQRYADALAIYERVLHADPRDRGAYTMRALTLSDLGSAQLAAE
AMWRHPNWFSQQERERLDNDRVARMIGWASAEPVDATHRYAETDQALANAARIQRDAPPQAAWEATRLRVDSLVALNQRQ
RHRDVIANYQALRAEGVDVPAYVLPTVGDSLMGLRRPAEAESVLRQALQHSPNDFNTQLLLGYALLEQERFDEAMPLFES
LAATQAPWPRREGATSGYENWDRFSADIALATARSAANDNRGAEALLRERAAIGPDNAELQAALASIEARRGQTMQALQR
NRMALTLDPHQKQARSGVVEAQRDLDRLDLADAAFASLQQEYPDDAGLQRLGASLERQRGWQVHLSHAWGRSENDTLTNS
TSPLGNHFGSSLLEAESPLLGERWRVGLRARDDWADFQATRVRYRSFWLGAHYRYDRLDFSAYGGRALDDFDRDGTAWAL
DAGWRFSDAWYGSVAWRTRDPEASLQARRLGITGDSIGAAVRWTPSDESRWELQARQLRYSDGNRRDQLDLFGSQRLWAN
PHVLVDGLFAASAGRAEDDRAVDYFNPRHSSAVAAGVRIEQIGWRRYDDAFRQRLEVTAGPTYQSGFGSRWVPALAYRHL
WSLGDGSALSYGVSWSRPVYDGQREQQLGLDLDFRWGGTP

Specific function: Exports the biofilm adhesin polysaccharide poly-beta- 1,6-N-acetyl-D-glucosamine (PGA) across the outer membrane. The PGA transported seems to be partially N-deacetylated since N- deacetylation of PGA by PgaB is needed for PGA export through the PgaA pori

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 TPR repeats [H]

Homologues:

Organism=Escherichia coli, GI1787261, Length=571, Percent_Identity=25.569176882662, Blast_Score=142, Evalue=5e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 76314; Mature: 76314

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS50293 TPR_REGION L=RR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTACVPQAHSGEVRSADVSGASTALTPMQQAEQFRGRQRYADALAIYERVLHADPRDRG
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
AYTMRALTLSDLGSAQLAAEAMWRHPNWFSQQERERLDNDRVARMIGWASAEPVDATHRY
CEEEEEEEHHHCCHHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHCCCCCCCCHHHHH
AETDQALANAARIQRDAPPQAAWEATRLRVDSLVALNQRQRHRDVIANYQALRAEGVDVP
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AYVLPTVGDSLMGLRRPAEAESVLRQALQHSPNDFNTQLLLGYALLEQERFDEAMPLFES
EEECCCCCHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LAATQAPWPRREGATSGYENWDRFSADIALATARSAANDNRGAEALLRERAAIGPDNAEL
HHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHH
QAALASIEARRGQTMQALQRNRMALTLDPHQKQARSGVVEAQRDLDRLDLADAAFASLQQ
HHHHHHHHHHCCHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EYPDDAGLQRLGASLERQRGWQVHLSHAWGRSENDTLTNSTSPLGNHFGSSLLEAESPLL
HCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCC
GERWRVGLRARDDWADFQATRVRYRSFWLGAHYRYDRLDFSAYGGRALDDFDRDGTAWAL
CHHHHCCCCCCCCHHHHHHHHHHHHHEEECCCEEECCCCCCCCCCCCCCCCCCCCCEEEE
DAGWRFSDAWYGSVAWRTRDPEASLQARRLGITGDSIGAAVRWTPSDESRWELQARQLRY
ECCCEECCCCCCEEEEECCCCCHHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHHHHC
SDGNRRDQLDLFGSQRLWANPHVLVDGLFAASAGRAEDDRAVDYFNPRHSSAVAAGVRIE
CCCCCCCCHHHCCCCCCCCCCCEEEHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHCCCHH
QIGWRRYDDAFRQRLEVTAGPTYQSGFGSRWVPALAYRHLWSLGDGSALSYGVSWSRPVY
HHCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCC
DGQREQQLGLDLDFRWGGTP
CCCHHHHCCCEEEECCCCCC
>Mature Secondary Structure
MFTACVPQAHSGEVRSADVSGASTALTPMQQAEQFRGRQRYADALAIYERVLHADPRDRG
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
AYTMRALTLSDLGSAQLAAEAMWRHPNWFSQQERERLDNDRVARMIGWASAEPVDATHRY
CEEEEEEEHHHCCHHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHCCCCCCCCHHHHH
AETDQALANAARIQRDAPPQAAWEATRLRVDSLVALNQRQRHRDVIANYQALRAEGVDVP
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AYVLPTVGDSLMGLRRPAEAESVLRQALQHSPNDFNTQLLLGYALLEQERFDEAMPLFES
EEECCCCCHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LAATQAPWPRREGATSGYENWDRFSADIALATARSAANDNRGAEALLRERAAIGPDNAEL
HHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHH
QAALASIEARRGQTMQALQRNRMALTLDPHQKQARSGVVEAQRDLDRLDLADAAFASLQQ
HHHHHHHHHHCCHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EYPDDAGLQRLGASLERQRGWQVHLSHAWGRSENDTLTNSTSPLGNHFGSSLLEAESPLL
HCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCC
GERWRVGLRARDDWADFQATRVRYRSFWLGAHYRYDRLDFSAYGGRALDDFDRDGTAWAL
CHHHHCCCCCCCCHHHHHHHHHHHHHEEECCCEEECCCCCCCCCCCCCCCCCCCCCEEEE
DAGWRFSDAWYGSVAWRTRDPEASLQARRLGITGDSIGAAVRWTPSDESRWELQARQLRY
ECCCEECCCCCCEEEEECCCCCHHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHHHHC
SDGNRRDQLDLFGSQRLWANPHVLVDGLFAASAGRAEDDRAVDYFNPRHSSAVAAGVRIE
CCCCCCCCHHHCCCCCCCCCCCEEEHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHCCCHH
QIGWRRYDDAFRQRLEVTAGPTYQSGFGSRWVPALAYRHLWSLGDGSALSYGVSWSRPVY
HHCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCC
DGQREQQLGLDLDFRWGGTP
CCCHHHHCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]