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The map label for this gene is amiC [H]

Identifier: 21242526

GI number: 21242526

Start: 2049724

End: 2050878

Strand: Direct

Name: amiC [H]

Synonym: XAC1780

Alternate gene names: 21242526

Gene position: 2049724-2050878 (Clockwise)

Preceding gene: 21242524

Following gene: 21242527

Centisome position: 39.6

GC content: 66.23

Gene sequence:

>1155_bases
ATGAAGCGCCGTCAACTACTACAGGGAGGCGCTGCCGCGGTGATGCTTTTGCCGGCGTTGGGGGCTGCACAAGGACTTCC
CGTCCTGCGGGGATGCAGCGTGCAGCAGCAGGGCCAGTCGCTGCGCCTTCGGCTGGAACTGGGCGCACAGGTTGCCTATC
GCAGTTTCCGGTTGACCGATCCCGAGCGGGTGGTCATCGACCTCTCTGGCGTGTCTTCGCAGTCGCCGCGCATCGATCCG
ATGCCTGCCGGTGCTGCGGTGGCCCGCATACGCAGCGCGCCACATCTGGATGGTCTGCGCGTCGTGCTCGACCTCCAGCA
GCCATGTTCGACCAACATGCACTGGGAAGGTGGCGCGCTAGTGCTGGAGCTTGCCGCCGCTGGCAGCGTCGCGTTGTCCA
CGAGCGACGCCGCTGCAGCGGCAGCGCCGACGGAGCCGACCCGCTCACGCCTGCGCCCCTACGTGGTTGCGATCGATGCC
GGCCACGGCGGCAAGGATCCGGGGGCGGTCAGTGTCGATGCGCGTTACGAAAAACATGTCGCCATGGCGGTCGCCGGGCG
GCTGCATCGACGCCTGGCGGCCGATGCGCGCTACCGGCCGACCATGATCCGCAGCGATGACCGCTTCGTGCCGTTGCACG
AGCGCGTGTTGATCGCGCATCGCCACAATGCGGACCTGTTCGTCTCCATCCATGCCGATGCCGCACCAACGCGCCAAGCG
CGCGGCGCCTCGGTCTTTGCGCTGTCGCAGACTGGCGCCAGCTCTGCGCTGGCGCGCTGGATCGCCGATAGCGAAAACGC
TGCCGACGACATGGGCGATATCGCGCGCCGGCTGCGGGTGCCGAGCAATCCGGTGTTGTCGCAGGTGCTGGCCGATCTGT
CGCTGAGCGGCACCATCGCCAGCAGCCTGGCATTCGGCACGTTGATGTTGGAGCGCCTGCAGCAGGTGACGCGCCTGCAT
CAAAACCAGGTGGGGCAGGCCGGTTTTGCGGTGTTGAAGTCGCCGGACATTCCGTCGCTGCTGGTAGAAACCGGCTTCAT
GAGCAATCGCGACGATTGCAGCCGCCTGTGCAGCGATACGCATCAGGACGAACTCGCGCAGACATTGCATGCGGGAATCG
ACGATTACTTCGCTGCGTTTCCTGGCCGCGCCTGA

Upstream 100 bases:

>100_bases
CCTGCCTCCCCTTGTGTTGGATGTGCTGTCTGGAATCGCGCCGCAGTCGGTGCTGCCGTCTGCTGTGTCGCGTCGACTGC
TTGGGTTTTGAGGTGCAGGC

Downstream 100 bases:

>100_bases
GGCGCGGTCGTCACCTTTATCTTCGACGAGACCCCGATGTCCCCTACGCTTCCCGATGTTGCTGTGACCGAACCATCAAC
GCTGAGCGCGCCCCTGCGAT

Product: N-acetylmuramoyl-L-alanine amidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MKRRQLLQGGAAAVMLLPALGAAQGLPVLRGCSVQQQGQSLRLRLELGAQVAYRSFRLTDPERVVIDLSGVSSQSPRIDP
MPAGAAVARIRSAPHLDGLRVVLDLQQPCSTNMHWEGGALVLELAAAGSVALSTSDAAAAAAPTEPTRSRLRPYVVAIDA
GHGGKDPGAVSVDARYEKHVAMAVAGRLHRRLAADARYRPTMIRSDDRFVPLHERVLIAHRHNADLFVSIHADAAPTRQA
RGASVFALSQTGASSALARWIADSENAADDMGDIARRLRVPSNPVLSQVLADLSLSGTIASSLAFGTLMLERLQQVTRLH
QNQVGQAGFAVLKSPDIPSLLVETGFMSNRDDCSRLCSDTHQDELAQTLHAGIDDYFAAFPGRA

Sequences:

>Translated_384_residues
MKRRQLLQGGAAAVMLLPALGAAQGLPVLRGCSVQQQGQSLRLRLELGAQVAYRSFRLTDPERVVIDLSGVSSQSPRIDP
MPAGAAVARIRSAPHLDGLRVVLDLQQPCSTNMHWEGGALVLELAAAGSVALSTSDAAAAAAPTEPTRSRLRPYVVAIDA
GHGGKDPGAVSVDARYEKHVAMAVAGRLHRRLAADARYRPTMIRSDDRFVPLHERVLIAHRHNADLFVSIHADAAPTRQA
RGASVFALSQTGASSALARWIADSENAADDMGDIARRLRVPSNPVLSQVLADLSLSGTIASSLAFGTLMLERLQQVTRLH
QNQVGQAGFAVLKSPDIPSLLVETGFMSNRDDCSRLCSDTHQDELAQTLHAGIDDYFAAFPGRA
>Mature_384_residues
MKRRQLLQGGAAAVMLLPALGAAQGLPVLRGCSVQQQGQSLRLRLELGAQVAYRSFRLTDPERVVIDLSGVSSQSPRIDP
MPAGAAVARIRSAPHLDGLRVVLDLQQPCSTNMHWEGGALVLELAAAGSVALSTSDAAAAAAPTEPTRSRLRPYVVAIDA
GHGGKDPGAVSVDARYEKHVAMAVAGRLHRRLAADARYRPTMIRSDDRFVPLHERVLIAHRHNADLFVSIHADAAPTRQA
RGASVFALSQTGASSALARWIADSENAADDMGDIARRLRVPSNPVLSQVLADLSLSGTIASSLAFGTLMLERLQQVTRLH
QNQVGQAGFAVLKSPDIPSLLVETGFMSNRDDCSRLCSDTHQDELAQTLHAGIDDYFAAFPGRA

Specific function: Cell-wall hydrolase involved in septum cleavage during cell division [H]

COG id: COG0860

COG function: function code M; N-acetylmuramoyl-L-alanine amidase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family [H]

Homologues:

Organism=Escherichia coli, GI87082163, Length=408, Percent_Identity=36.0294117647059, Blast_Score=225, Evalue=3e-60,
Organism=Escherichia coli, GI1788776, Length=229, Percent_Identity=42.7947598253275, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1790611, Length=228, Percent_Identity=39.9122807017544, Blast_Score=173, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021731
- InterPro:   IPR002508
- InterPro:   IPR006311 [H]

Pfam domain/function: PF01520 Amidase_3; PF11741 AMIN [H]

EC number: =3.5.1.28 [H]

Molecular weight: Translated: 40954; Mature: 40954

Theoretical pI: Translated: 8.65; Mature: 8.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRRQLLQGGAAAVMLLPALGAAQGLPVLRGCSVQQQGQSLRLRLELGAQVAYRSFRLTD
CCHHHHHCCCCHHHHHHHHHCCCCCCCHHHCCCHHHCCCEEEEEEEECCHHHHHEEECCC
PERVVIDLSGVSSQSPRIDPMPAGAAVARIRSAPHLDGLRVVLDLQQPCSTNMHWEGGAL
CCEEEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCEE
VLELAAAGSVALSTSDAAAAAAPTEPTRSRLRPYVVAIDAGHGGKDPGAVSVDARYEKHV
EEEEECCCCEEEECCCCHHCCCCCCCHHHCCCCEEEEEECCCCCCCCCEEEECCHHHHHH
AMAVAGRLHRRLAADARYRPTMIRSDDRFVPLHERVLIAHRHNADLFVSIHADAAPTRQA
HHHHHHHHHHHHHHCCCCCCCEECCCCCEECHHHEEEEEEECCCEEEEEEECCCCCCCCC
RGASVFALSQTGASSALARWIADSENAADDMGDIARRLRVPSNPVLSQVLADLSLSGTIA
CCCEEEEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHH
SSLAFGTLMLERLQQVTRLHQNQVGQAGFAVLKSPDIPSLLVETGFMSNRDDCSRLCSDT
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEECCCCCCHHHHHHCCCCCHHHHHHHHCCC
HQDELAQTLHAGIDDYFAAFPGRA
CHHHHHHHHHHCHHHHHHHCCCCC
>Mature Secondary Structure
MKRRQLLQGGAAAVMLLPALGAAQGLPVLRGCSVQQQGQSLRLRLELGAQVAYRSFRLTD
CCHHHHHCCCCHHHHHHHHHCCCCCCCHHHCCCHHHCCCEEEEEEEECCHHHHHEEECCC
PERVVIDLSGVSSQSPRIDPMPAGAAVARIRSAPHLDGLRVVLDLQQPCSTNMHWEGGAL
CCEEEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCEE
VLELAAAGSVALSTSDAAAAAAPTEPTRSRLRPYVVAIDAGHGGKDPGAVSVDARYEKHV
EEEEECCCCEEEECCCCHHCCCCCCCHHHCCCCEEEEEECCCCCCCCCEEEECCHHHHHH
AMAVAGRLHRRLAADARYRPTMIRSDDRFVPLHERVLIAHRHNADLFVSIHADAAPTRQA
HHHHHHHHHHHHHHCCCCCCCEECCCCCEECHHHEEEEEEECCCEEEEEEECCCCCCCCC
RGASVFALSQTGASSALARWIADSENAADDMGDIARRLRVPSNPVLSQVLADLSLSGTIA
CCCEEEEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHH
SSLAFGTLMLERLQQVTRLHQNQVGQAGFAVLKSPDIPSLLVETGFMSNRDDCSRLCSDT
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEECCCCCCHHHHHHCCCCCHHHHHHHHCCC
HQDELAQTLHAGIDDYFAAFPGRA
CHHHHHHHHHHCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]