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The map label for this gene is surE

Identifier: 21242474

GI number: 21242474

Start: 1985854

End: 1986633

Strand: Direct

Name: surE

Synonym: XAC1725

Alternate gene names: 21242474

Gene position: 1985854-1986633 (Clockwise)

Preceding gene: 21242472

Following gene: 21242475

Centisome position: 38.37

GC content: 67.56

Gene sequence:

>780_bases
ATGCGCGTACTGGTTAGCAACGACGACGGTGTCGACGCCCCCGGCATCCAGGTTTTGGCCGAGGCGCTGCGCCATGCCGG
TCATGAAGTGATGGTGGTCGCGCCCGACCGCGACCGCTCCGGCGCCAGCAATTCGCTCACGCTGGATGTGCCGATCCGCA
CCCGCCGCATCGACGCGCAGACCTGCGCAGTGGCCGGCACGCCCACCGACTGCGTGCATCTGGCGCTCACCGGCATGCTC
GATTACGACCCGGACATCGTGGTCTCCGGCATCAACAACTCGGCCAATCTGGGCGACGACGTGATCTATTCGGGCACCGT
GTCGGCCGCAATGGAAGGCCGCTTCCTCGGCTTGCCGGCGGTGGCGGTGTCGCTGGTCACGCACAACCACCAAGCGCACA
ACTACGACACCGCCGCGCGCGCTGCGGTGGAAATCGTGGCGCGGCTGAAGGCCGACCCGTTGCCTGCCGACACCATCCTC
AACGTCAACGTGCCGGATCTGGCATGGTCGGATGTGCTCGGTTTCGAAGTCACCCGGCTCGGCAATCGCCACCGGTCCGA
GCCGTGCGTGCCGCAGCGCGATCCGCGCGGCCACACCGTGTACTGGATCGGCCCGGCCGGTCCCGAGCAGGATGCTGGCG
CCGGTACCGATTTCCACGCCGTGCGTACCGGACATATCTCGATCACGCCGATCCACGTCGATCTCACCCGTTACCAGGCA
CTGGACACCGTTGCCGGCTGGGTGGGTGGGCTGACCGCAGCGCTGGACGGCCCGGCATGA

Upstream 100 bases:

>100_bases
TTGGCACAGCGTACCCGGTCCAAGCGCAGACGCACGCGAAGATCAAGCGCGAAGGCGCGGGACGCATCCGGTATCATGGC
CCGGTTTTCCGAGGAGTCCC

Downstream 100 bases:

>100_bases
CGCCGAGGCTGCGCCTGCAACCGGAATCGGTCGGGATCGGCATGACCTCGCAGCGCGTGCGCGACCGCCTGGTCGAGCGC
CTGCGCGAGGCCGGCATCCA

Product: stationary phase survival protein SurE

Products: NA

Alternate protein names: Nucleoside 5'-monophosphate phosphohydrolase

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MRVLVSNDDGVDAPGIQVLAEALRHAGHEVMVVAPDRDRSGASNSLTLDVPIRTRRIDAQTCAVAGTPTDCVHLALTGML
DYDPDIVVSGINNSANLGDDVIYSGTVSAAMEGRFLGLPAVAVSLVTHNHQAHNYDTAARAAVEIVARLKADPLPADTIL
NVNVPDLAWSDVLGFEVTRLGNRHRSEPCVPQRDPRGHTVYWIGPAGPEQDAGAGTDFHAVRTGHISITPIHVDLTRYQA
LDTVAGWVGGLTAALDGPA

Sequences:

>Translated_259_residues
MRVLVSNDDGVDAPGIQVLAEALRHAGHEVMVVAPDRDRSGASNSLTLDVPIRTRRIDAQTCAVAGTPTDCVHLALTGML
DYDPDIVVSGINNSANLGDDVIYSGTVSAAMEGRFLGLPAVAVSLVTHNHQAHNYDTAARAAVEIVARLKADPLPADTIL
NVNVPDLAWSDVLGFEVTRLGNRHRSEPCVPQRDPRGHTVYWIGPAGPEQDAGAGTDFHAVRTGHISITPIHVDLTRYQA
LDTVAGWVGGLTAALDGPA
>Mature_259_residues
MRVLVSNDDGVDAPGIQVLAEALRHAGHEVMVVAPDRDRSGASNSLTLDVPIRTRRIDAQTCAVAGTPTDCVHLALTGML
DYDPDIVVSGINNSANLGDDVIYSGTVSAAMEGRFLGLPAVAVSLVTHNHQAHNYDTAARAAVEIVARLKADPLPADTIL
NVNVPDLAWSDVLGFEVTRLGNRHRSEPCVPQRDPRGHTVYWIGPAGPEQDAGAGTDFHAVRTGHISITPIHVDLTRYQA
LDTVAGWVGGLTAALDGPA

Specific function: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family

Homologues:

Organism=Escherichia coli, GI1789101, Length=249, Percent_Identity=58.2329317269076, Blast_Score=270, Evalue=1e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SURE_XANAC (Q8PLR4)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_642056.1
- ProteinModelPortal:   Q8PLR4
- SMR:   Q8PLR4
- GeneID:   1155796
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC1725
- NMPDR:   fig|190486.1.peg.1700
- HOGENOM:   HBG600532
- OMA:   SINVIYS
- ProtClustDB:   PRK00346
- BioCyc:   XAXO190486:XAC1725-MONOMER
- BRENDA:   3.1.3.5
- GO:   GO:0005737
- HAMAP:   MF_00060
- InterPro:   IPR002828
- Gene3D:   G3DSA:3.40.1210.10
- TIGRFAMs:   TIGR00087

Pfam domain/function: PF01975 SurE; SSF64167 SurE-like_Pase/nucleotidase

EC number: =3.1.3.5

Molecular weight: Translated: 27335; Mature: 27335

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLVSNDDGVDAPGIQVLAEALRHAGHEVMVVAPDRDRSGASNSLTLDVPIRTRRIDAQ
CEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEEECCEEEEECCH
TCAVAGTPTDCVHLALTGMLDYDPDIVVSGINNSANLGDDVIYSGTVSAAMEGRFLGLPA
HEEECCCCHHHHHEEECCCCCCCCCEEEECCCCCCCCCCCEEECCCHHHHHCCEEECCHH
VAVSLVTHNHQAHNYDTAARAAVEIVARLKADPLPADTILNVNVPDLAWSDVLGFEVTRL
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHH
GNRHRSEPCVPQRDPRGHTVYWIGPAGPEQDAGAGTDFHAVRTGHISITPIHVDLTRYQA
CCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCEEEEEEEEEHHHHHH
LDTVAGWVGGLTAALDGPA
HHHHHHHHHHHHEECCCCC
>Mature Secondary Structure
MRVLVSNDDGVDAPGIQVLAEALRHAGHEVMVVAPDRDRSGASNSLTLDVPIRTRRIDAQ
CEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEEECCEEEEECCH
TCAVAGTPTDCVHLALTGMLDYDPDIVVSGINNSANLGDDVIYSGTVSAAMEGRFLGLPA
HEEECCCCHHHHHEEECCCCCCCCCEEEECCCCCCCCCCCEEECCCHHHHHCCEEECCHH
VAVSLVTHNHQAHNYDTAARAAVEIVARLKADPLPADTILNVNVPDLAWSDVLGFEVTRL
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHH
GNRHRSEPCVPQRDPRGHTVYWIGPAGPEQDAGAGTDFHAVRTGHISITPIHVDLTRYQA
CCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCEEEEEEEEEHHHHHH
LDTVAGWVGGLTAALDGPA
HHHHHHHHHHHHEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217