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The map label for this gene is bioC [H]

Identifier: 21242447

GI number: 21242447

Start: 1955347

End: 1956045

Strand: Direct

Name: bioC [H]

Synonym: XAC1698

Alternate gene names: 21242447

Gene position: 1955347-1956045 (Clockwise)

Preceding gene: 21242446

Following gene: 21242448

Centisome position: 37.78

GC content: 68.1

Gene sequence:

>699_bases
GTGAGCGCAGTGCCGGTGCTCGAGCCCGCTGCTGCGTACGCACTGTGGGCGCAGGCGTATCCACCGCATGCGCACAACCC
GGTGATGCTGGCCGAAGAGCGCGCCATGCTCGCATTGATGCCGTCCAGCCTGCAGGGCCAACACGTGCTGGACGCCGGCT
GCGGCAGCGGCCGCTACATGCTGCACGCACTGCGCCGTGGCGCCCGGCAAGTGACCGGTGTCGACCTGTCGCCGCAGATG
CTGCACCGTGCCGGTGCCGAGCTCGCACAGGACTGGCCGGCCGCACGCATCGTTTTGCAACAAGGCAGCCTGGATCAGTT
GCCGTTGGCCGATACGGTGGCCGACCTGAGCGTGTGCGGTCTGGTGCTGGGGCACCTGCAACAGCTGTGGCCGGCGCTGG
AAGAACTGCATCGCGTCACCCGCGTCGGCGGCATCGTGCTGTGCAGCGACGTCCACCCGATCGGCCACGCATTGGGCTGG
CGGCGCGACTTCAAGGCCGATGGGCAGCACTACGCGGTCCGCCACACCCAGCATCTCTATAGCCACTGGCATTCGGCATG
CACCGCACTCGGGTTCGCGATCCAAGCCGTGTCCGAGCCGATGCTGGACCCTGCGGATATCCCGGCCGGGGCGCGTTTCG
ACCAGATGGCGTTGCAGGTGCCGGTTGCGCTGGTGCTACGGCTGAGACGGATCGCGTGA

Upstream 100 bases:

>100_bases
TCTCAACGTGCATAACACGCTCTAAGCGTTTAACGCGGGAGCAGCCGGCGCAGGCCACCGCGCAGGTGACCCATGCGCTG
GCTGCCAACCGAGCGCTTTC

Downstream 100 bases:

>100_bases
GCAAGATCTTGCACACCGCAGCGGCTGTCTGTGCGTTGGGCGCTGCCGATCAGTGGCACGCTGCGGTCGCAGCGGCACAC
GGCAACGACGTGGCGTCGAT

Product: biotin synthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MSAVPVLEPAAAYALWAQAYPPHAHNPVMLAEERAMLALMPSSLQGQHVLDAGCGSGRYMLHALRRGARQVTGVDLSPQM
LHRAGAELAQDWPAARIVLQQGSLDQLPLADTVADLSVCGLVLGHLQQLWPALEELHRVTRVGGIVLCSDVHPIGHALGW
RRDFKADGQHYAVRHTQHLYSHWHSACTALGFAIQAVSEPMLDPADIPAGARFDQMALQVPVALVLRLRRIA

Sequences:

>Translated_232_residues
MSAVPVLEPAAAYALWAQAYPPHAHNPVMLAEERAMLALMPSSLQGQHVLDAGCGSGRYMLHALRRGARQVTGVDLSPQM
LHRAGAELAQDWPAARIVLQQGSLDQLPLADTVADLSVCGLVLGHLQQLWPALEELHRVTRVGGIVLCSDVHPIGHALGW
RRDFKADGQHYAVRHTQHLYSHWHSACTALGFAIQAVSEPMLDPADIPAGARFDQMALQVPVALVLRLRRIA
>Mature_231_residues
SAVPVLEPAAAYALWAQAYPPHAHNPVMLAEERAMLALMPSSLQGQHVLDAGCGSGRYMLHALRRGARQVTGVDLSPQML
HRAGAELAQDWPAARIVLQQGSLDQLPLADTVADLSVCGLVLGHLQQLWPALEELHRVTRVGGIVLCSDVHPIGHALGWR
RDFKADGQHYAVRHTQHLYSHWHSACTALGFAIQAVSEPMLDPADIPAGARFDQMALQVPVALVLRLRRIA

Specific function: BioC is involved in an early, but chemically unexplored, step in the conversion of pimelic acid to biotin [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

Organism=Escherichia coli, GI1786994, Length=112, Percent_Identity=41.9642857142857, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011814
- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: NA

Molecular weight: Translated: 25227; Mature: 25095

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVPVLEPAAAYALWAQAYPPHAHNPVMLAEERAMLALMPSSLQGQHVLDAGCGSGRYM
CCCCCCCCHHHHHHHHHHCCCCCCCCCEEEECCCHHEEECCCCCCCCCCCCCCCCCCHHH
LHALRRGARQVTGVDLSPQMLHRAGAELAQDWPAARIVLQQGSLDQLPLADTVADLSVCG
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHEEECCCCCCCCCCHHHHHHHHHHH
LVLGHLQQLWPALEELHRVTRVGGIVLCSDVHPIGHALGWRRDFKADGQHYAVRHTQHLY
HHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHH
SHWHSACTALGFAIQAVSEPMLDPADIPAGARFDQMALQVPVALVLRLRRIA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SAVPVLEPAAAYALWAQAYPPHAHNPVMLAEERAMLALMPSSLQGQHVLDAGCGSGRYM
CCCCCCCHHHHHHHHHHCCCCCCCCCEEEECCCHHEEECCCCCCCCCCCCCCCCCCHHH
LHALRRGARQVTGVDLSPQMLHRAGAELAQDWPAARIVLQQGSLDQLPLADTVADLSVCG
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHEEECCCCCCCCCCHHHHHHHHHHH
LVLGHLQQLWPALEELHRVTRVGGIVLCSDVHPIGHALGWRRDFKADGQHYAVRHTQHLY
HHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHH
SHWHSACTALGFAIQAVSEPMLDPADIPAGARFDQMALQVPVALVLRLRRIA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8250549 [H]