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The map label for this gene is smc [H]

Identifier: 21242373

GI number: 21242373

Start: 1866710

End: 1870345

Strand: Direct

Name: smc [H]

Synonym: XAC1623

Alternate gene names: 21242373

Gene position: 1866710-1870345 (Clockwise)

Preceding gene: 21242372

Following gene: 21242374

Centisome position: 36.07

GC content: 65.46

Gene sequence:

>3636_bases
ATGCCCGTTATACTCATGCCCCATTGCCGGTTCCACGGCCCGCGGATCTTATGGATCAAGGGCTTGGGCGCTGGCTTCAC
AGGAAAAGCGCCTGCCGGCCTCGTCCGTGCGGTGCCCGGAATCTCCAGCCCCATGCGCCTGTCCACGATCAAGCTGTCCG
GTTTCAAGTCGTTCGTCGACCCGACCACGTTGCACCTGCCCACCAACATGACCGGCATCGTCGGCCCCAATGGCTGCGGC
AAGTCCAACATCATCGATGCGGTGCGCTGGGTGATGGGCGAGAGCTCGGCCAGCCGCCTACGTGGCGATTCGTTGACCGA
CGTGATCTTTTCCGGCTCTTCGGCACGCAAGCCGGTGTCGCAGGCGACGGTGGAGCTGATCTTCGACAACTCCGACCACA
CCATCAGTGGCGAGTTCGCCTCGTTCAACGAGATTTCGGTCAAGCGCCTGGTCAGTCGCGACGGCAATAGCGCCTACTAC
CTCAATGGCACCAAGTGCCGGCGCCGCGACATCACCGATCTGTTCCTGGGCACCGGCCTTGGGCCGCGCAGCTACTCGAT
CATCGAGCAGGGCATGATCAGCCAAATCATCGAAGCACGCCCGGAAGACCTGCGCGTGTATCTGGAAGAAGCCGCCGGCA
TTTCCAAGTACAAGGAACGCCGCAAGGAAACCGAAACGCGGATTCGGCATACGCGCGAAAACCTCGACCGTCTGAGCGAC
CTGCGCGAAGAAATCACCAAGCAATTGGCGCATCTGCAGCGCCAGGCGCGGCAGGCCGAGCAATACCAGGCGTTGCAGGA
AGAGCGCCGGATCAAGGATGCCGAGTGGAAGGCGCTGGAATACCGCGGCCTGGATGGTCGGTTGCAGGGCCTGCGCGAGA
AGTTGAATCAGGAAGAGACACGCCTGCAGCAATTGATTGCCGAGCAGCGCGATGCCGAAGCACGCATCGAAACCGGCCGC
GTGCGCCGCGAAGAAGCCGCCGAAGCGGTGGCCAAGGCACAGGCCGATGTCTACCAGGTCGGTGGCGCCTTGGCGCGTAT
CGAGCAGCAGATCCAGCATCAGCGCGAACTCTCGCATCGCCTGCACAAGGCGCGCGATGAGGCGCAGAGCCAGCTGCAGG
AATTGACCCAGCACATCAGCGGCGACTCGGCCAAATTGAGCGTGCTGCGCGAAGCGGTGGCCACTGCCGAACCGCAACTG
GAGCAGCTGCGCGAAGACCACGAATTCCGCCAGGAGTCGCTACGCGAAGCCGAAGCGCGGCTGGCCGACTGGCAGCAGCG
CTGGGAAACGCATAACCGCGACACCGGCGAGGCCTCGCGTGCCGGTGAAGTGGAACGCACGCGCGTCGATTATCTGGATC
GCCAGGCGCTGGAAGCCGACCGCCGCCGCGAAGCGTTGGTCAATGAGCGCGCTGGGCTCGACCTCGAGGCATTGGCCGAG
GCGTTCGAGCAGATCGAACTGCGCCATGAAACCCAGAAGACCTCGCTGGACGGGCTGACCGAGCAGGTCGAGGCGCGCAA
GCACGCGCTCGCTGGGCTGCAGGAACAGCAACGCGCCAGCCAGGGCGAGCTGGCCGAAGTGCGCAAGCAGGCGCAGGCCG
CGCGCGGTCGGTTGTCGTCGCTGGAAACCTTGCAACAGGCCGCGCTTGGCCAGGAGCAGGGCGCCGCAGTGGCGTGGCTG
AAGTCGCGCGGACTGGATTCGTCCGCGCGCGTGGGCGAGCGCATCAGCGTCGAGAGCGGCTGGGAAAATGCAGTCGAAGG
CGCCCTGGGGCAGTTGATCGAAGGCGTGCTGGTGGAGGCGCCGGAACAATTGGTCGATGCGCTGGGCGAGTTGGGCGATG
GCCGCATCGCGTTGGTGTCCAGTGCGACTGACAATGCGAGCTTCGCGCCGACCTCGCTGGCCGCCAAGGTGCAGGGGCCG
ATCGCGATCCGTCGGCTGCTTGCGCGTCTGCACACCGCCGAGGACCTGGACGCTGCGCGCACGCTGCAACGCAGCCTGCC
CGAAGGCGATTCGGTGATCACCCGCAATGGCGAGCGGCTAGGCGAGGGTTGGGTGCGGGTCTCGCGCTCGGGCGCGGCCA
AGCAGGGCGCGCTGCTGCGTGAGCGCGAGATCCAGGAGCTGCGCACCCAGATCGAAACCCTGCAAGAGCGCGAAGCCGAG
CTTGAGCACCAGCTGTCCAGCTTCCGCGAACAACTGCTGGCGGCAGAGCAGCAGCGCGAAGACGCGCAGCGCCAGCTGTA
TATGGCGCACCGCAGCGTCTCCGAACTGGCTGGGCAATTGCAGAGTCAGCAAGGCAAGGTGGACGCGGCGCGCACGCGCA
TCGAGCGCATCGAAACCGAATTGGCGCAACTGCTGGAAACGCTCGATACCAGCCGCGAGCAGGCACGCGAAGCGCGCGCC
AAACTCGAAGACGCGGTCACCTTGATGGGCGATCTGCAGGGCACGCGCGAAGCGCTGGAAAGCGAGCGCCGTCAACTCAC
CGATGCACGCGATCAGGCGCGAGATGCCGCGCGCGGCGTGCGCGATGCAATGCATGCATTGGCGCTGACGCTGGAGTCGC
AACGCACCCAGATCGCATCGCTGAGCCAGACCCTGGAACGCATGGACAGCCAGCGCGGGCAGCTCGATACGCGCCTGGAA
GATCTGGTCGCCCAGCTGAGCGAAGGCGATTCGCCGGTGGAAACACTGGAACACGAACACCAGGCCGCGTTGAGCGAGCG
CGTACGCACCGAGCGCGCGCTGGGCGAAGCGCGCACCCTGCTCGACAGCATCGACAGCGAGCTGCGCAGCTTCGAACAGA
CCCGCCAGCAACGCGACGAACAAGCGTTGGCGCAGCGCGAACGCATTTCGCAACGCAAGCTCGATCAACAGGCGCTGGTG
CTCAATGCCGAGCAACTGGAAGCGGCGGTGGTCAAGGCAGGCTTCGTGCTGGAAGAGGTGGTCAACGGGTTGCCCGAGTC
GGCCAACGTGGCCGAATGGGAAGCGGCCGTTGGCCAGATCGACGGGCGCATGCGTCGCCTGGAGCCGGTGAACCTGGCCG
CCATCCAGGAATACGGCGAAGCCGCGCAACGCTCCGAGTATCTGGACGCGCAGAACCTGGACCTCAATACCGCGCTGGAA
ACGTTGGAAGAGGCCATTCGCAAGATCGATCGCGAGACCCGTGGCCGCTTCAAGGACACCTTCGACCGGGTCAATTCCGG
CGTGCAGGCGCTGTACCCGCGCCTGTTCGGCGGCGGCCATGCGTATCTGGAACTCACCGGCGAAGACCTGCTCGACACCG
GCGTCACCATCATGGCGCGCCCTCCGGGCAAGCGCGTGTCGAGCATTTCGCTGCTGTCCGGCGGCGAGAAGGCGATGACC
GCGGTGGCGCTGGTGTTTGCGATTTTCCAGCTCAACCCGGCGCCGTTCTGCCTGCTCGACGAAGTGGACGCGCCGCTTGA
CGAAGCCAACGTCGGTCGCCTTGCCAACATGGTGCGCGAGATGAGCGAGAAGGTGCAGTTCCTGTTCGTCAGCCATAACA
AGGCCACGATGGAGGCCGCGCGCCAGCTCTCCGGCGTGACCATGCGCGAGCCCGGCGTCAGCCGCCTGGTCAGCGTGGAC
CTGGAAGAGGCCGCACGTTTGGCGGGTGCGGCATGA

Upstream 100 bases:

>100_bases
TCATCGTCGAATCCGACGCCTGATCCAGGCCATATGTGTCACCCGAAGGGCGCCTTGTGAGGCGCCCTTCGTTTTTTGGG
GCGCCGCCGCCAGCGCTGGC

Downstream 100 bases:

>100_bases
CGTGCCATGCTTGCCGGAATATCGACACCTGTCACTCTTATGCGGAGGCACGCTGAATGTCCGACATGGCCATGATCCGG
ATCGGGATCCTGATCGCTGG

Product: chromosome segregation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1211; Mature: 1210

Protein sequence:

>1211_residues
MPVILMPHCRFHGPRILWIKGLGAGFTGKAPAGLVRAVPGISSPMRLSTIKLSGFKSFVDPTTLHLPTNMTGIVGPNGCG
KSNIIDAVRWVMGESSASRLRGDSLTDVIFSGSSARKPVSQATVELIFDNSDHTISGEFASFNEISVKRLVSRDGNSAYY
LNGTKCRRRDITDLFLGTGLGPRSYSIIEQGMISQIIEARPEDLRVYLEEAAGISKYKERRKETETRIRHTRENLDRLSD
LREEITKQLAHLQRQARQAEQYQALQEERRIKDAEWKALEYRGLDGRLQGLREKLNQEETRLQQLIAEQRDAEARIETGR
VRREEAAEAVAKAQADVYQVGGALARIEQQIQHQRELSHRLHKARDEAQSQLQELTQHISGDSAKLSVLREAVATAEPQL
EQLREDHEFRQESLREAEARLADWQQRWETHNRDTGEASRAGEVERTRVDYLDRQALEADRRREALVNERAGLDLEALAE
AFEQIELRHETQKTSLDGLTEQVEARKHALAGLQEQQRASQGELAEVRKQAQAARGRLSSLETLQQAALGQEQGAAVAWL
KSRGLDSSARVGERISVESGWENAVEGALGQLIEGVLVEAPEQLVDALGELGDGRIALVSSATDNASFAPTSLAAKVQGP
IAIRRLLARLHTAEDLDAARTLQRSLPEGDSVITRNGERLGEGWVRVSRSGAAKQGALLREREIQELRTQIETLQEREAE
LEHQLSSFREQLLAAEQQREDAQRQLYMAHRSVSELAGQLQSQQGKVDAARTRIERIETELAQLLETLDTSREQAREARA
KLEDAVTLMGDLQGTREALESERRQLTDARDQARDAARGVRDAMHALALTLESQRTQIASLSQTLERMDSQRGQLDTRLE
DLVAQLSEGDSPVETLEHEHQAALSERVRTERALGEARTLLDSIDSELRSFEQTRQQRDEQALAQRERISQRKLDQQALV
LNAEQLEAAVVKAGFVLEEVVNGLPESANVAEWEAAVGQIDGRMRRLEPVNLAAIQEYGEAAQRSEYLDAQNLDLNTALE
TLEEAIRKIDRETRGRFKDTFDRVNSGVQALYPRLFGGGHAYLELTGEDLLDTGVTIMARPPGKRVSSISLLSGGEKAMT
AVALVFAIFQLNPAPFCLLDEVDAPLDEANVGRLANMVREMSEKVQFLFVSHNKATMEAARQLSGVTMREPGVSRLVSVD
LEEAARLAGAA

Sequences:

>Translated_1211_residues
MPVILMPHCRFHGPRILWIKGLGAGFTGKAPAGLVRAVPGISSPMRLSTIKLSGFKSFVDPTTLHLPTNMTGIVGPNGCG
KSNIIDAVRWVMGESSASRLRGDSLTDVIFSGSSARKPVSQATVELIFDNSDHTISGEFASFNEISVKRLVSRDGNSAYY
LNGTKCRRRDITDLFLGTGLGPRSYSIIEQGMISQIIEARPEDLRVYLEEAAGISKYKERRKETETRIRHTRENLDRLSD
LREEITKQLAHLQRQARQAEQYQALQEERRIKDAEWKALEYRGLDGRLQGLREKLNQEETRLQQLIAEQRDAEARIETGR
VRREEAAEAVAKAQADVYQVGGALARIEQQIQHQRELSHRLHKARDEAQSQLQELTQHISGDSAKLSVLREAVATAEPQL
EQLREDHEFRQESLREAEARLADWQQRWETHNRDTGEASRAGEVERTRVDYLDRQALEADRRREALVNERAGLDLEALAE
AFEQIELRHETQKTSLDGLTEQVEARKHALAGLQEQQRASQGELAEVRKQAQAARGRLSSLETLQQAALGQEQGAAVAWL
KSRGLDSSARVGERISVESGWENAVEGALGQLIEGVLVEAPEQLVDALGELGDGRIALVSSATDNASFAPTSLAAKVQGP
IAIRRLLARLHTAEDLDAARTLQRSLPEGDSVITRNGERLGEGWVRVSRSGAAKQGALLREREIQELRTQIETLQEREAE
LEHQLSSFREQLLAAEQQREDAQRQLYMAHRSVSELAGQLQSQQGKVDAARTRIERIETELAQLLETLDTSREQAREARA
KLEDAVTLMGDLQGTREALESERRQLTDARDQARDAARGVRDAMHALALTLESQRTQIASLSQTLERMDSQRGQLDTRLE
DLVAQLSEGDSPVETLEHEHQAALSERVRTERALGEARTLLDSIDSELRSFEQTRQQRDEQALAQRERISQRKLDQQALV
LNAEQLEAAVVKAGFVLEEVVNGLPESANVAEWEAAVGQIDGRMRRLEPVNLAAIQEYGEAAQRSEYLDAQNLDLNTALE
TLEEAIRKIDRETRGRFKDTFDRVNSGVQALYPRLFGGGHAYLELTGEDLLDTGVTIMARPPGKRVSSISLLSGGEKAMT
AVALVFAIFQLNPAPFCLLDEVDAPLDEANVGRLANMVREMSEKVQFLFVSHNKATMEAARQLSGVTMREPGVSRLVSVD
LEEAARLAGAA
>Mature_1210_residues
PVILMPHCRFHGPRILWIKGLGAGFTGKAPAGLVRAVPGISSPMRLSTIKLSGFKSFVDPTTLHLPTNMTGIVGPNGCGK
SNIIDAVRWVMGESSASRLRGDSLTDVIFSGSSARKPVSQATVELIFDNSDHTISGEFASFNEISVKRLVSRDGNSAYYL
NGTKCRRRDITDLFLGTGLGPRSYSIIEQGMISQIIEARPEDLRVYLEEAAGISKYKERRKETETRIRHTRENLDRLSDL
REEITKQLAHLQRQARQAEQYQALQEERRIKDAEWKALEYRGLDGRLQGLREKLNQEETRLQQLIAEQRDAEARIETGRV
RREEAAEAVAKAQADVYQVGGALARIEQQIQHQRELSHRLHKARDEAQSQLQELTQHISGDSAKLSVLREAVATAEPQLE
QLREDHEFRQESLREAEARLADWQQRWETHNRDTGEASRAGEVERTRVDYLDRQALEADRRREALVNERAGLDLEALAEA
FEQIELRHETQKTSLDGLTEQVEARKHALAGLQEQQRASQGELAEVRKQAQAARGRLSSLETLQQAALGQEQGAAVAWLK
SRGLDSSARVGERISVESGWENAVEGALGQLIEGVLVEAPEQLVDALGELGDGRIALVSSATDNASFAPTSLAAKVQGPI
AIRRLLARLHTAEDLDAARTLQRSLPEGDSVITRNGERLGEGWVRVSRSGAAKQGALLREREIQELRTQIETLQEREAEL
EHQLSSFREQLLAAEQQREDAQRQLYMAHRSVSELAGQLQSQQGKVDAARTRIERIETELAQLLETLDTSREQAREARAK
LEDAVTLMGDLQGTREALESERRQLTDARDQARDAARGVRDAMHALALTLESQRTQIASLSQTLERMDSQRGQLDTRLED
LVAQLSEGDSPVETLEHEHQAALSERVRTERALGEARTLLDSIDSELRSFEQTRQQRDEQALAQRERISQRKLDQQALVL
NAEQLEAAVVKAGFVLEEVVNGLPESANVAEWEAAVGQIDGRMRRLEPVNLAAIQEYGEAAQRSEYLDAQNLDLNTALET
LEEAIRKIDRETRGRFKDTFDRVNSGVQALYPRLFGGGHAYLELTGEDLLDTGVTIMARPPGKRVSSISLLSGGEKAMTA
VALVFAIFQLNPAPFCLLDEVDAPLDEANVGRLANMVREMSEKVQFLFVSHNKATMEAARQLSGVTMREPGVSRLVSVDL
EEAARLAGAA

Specific function: Plays an important role in chromosome structure and partitioning. Essential for chromosome partition [H]

COG id: COG1196

COG function: function code D; Chromosome segregation ATPases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SMC family [H]

Homologues:

Organism=Homo sapiens, GI110347425, Length=486, Percent_Identity=25.9259259259259, Blast_Score=123, Evalue=1e-27,
Organism=Homo sapiens, GI110347420, Length=486, Percent_Identity=25.9259259259259, Blast_Score=123, Evalue=1e-27,
Organism=Homo sapiens, GI110347418, Length=486, Percent_Identity=25.9259259259259, Blast_Score=123, Evalue=1e-27,
Organism=Homo sapiens, GI50658065, Length=392, Percent_Identity=23.2142857142857, Blast_Score=98, Evalue=6e-20,
Organism=Homo sapiens, GI50658063, Length=392, Percent_Identity=23.2142857142857, Blast_Score=98, Evalue=6e-20,
Organism=Homo sapiens, GI4885399, Length=256, Percent_Identity=29.296875, Blast_Score=98, Evalue=6e-20,
Organism=Homo sapiens, GI30581135, Length=166, Percent_Identity=36.144578313253, Blast_Score=97, Evalue=1e-19,
Organism=Homo sapiens, GI71565160, Length=151, Percent_Identity=31.7880794701987, Blast_Score=90, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI212656546, Length=1306, Percent_Identity=20.6738131699847, Blast_Score=143, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI193210872, Length=1278, Percent_Identity=20.8920187793427, Blast_Score=138, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17553272, Length=195, Percent_Identity=31.2820512820513, Blast_Score=103, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17535279, Length=277, Percent_Identity=27.7978339350181, Blast_Score=102, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI193202684, Length=195, Percent_Identity=29.2307692307692, Blast_Score=91, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17552844, Length=136, Percent_Identity=32.3529411764706, Blast_Score=80, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI115532288, Length=100, Percent_Identity=41, Blast_Score=75, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322387, Length=1275, Percent_Identity=21.0980392156863, Blast_Score=147, Evalue=7e-36,
Organism=Saccharomyces cerevisiae, GI6321144, Length=265, Percent_Identity=30.5660377358491, Blast_Score=119, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6321104, Length=226, Percent_Identity=32.3008849557522, Blast_Score=114, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6323115, Length=223, Percent_Identity=31.8385650224215, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24642555, Length=1272, Percent_Identity=21.6194968553459, Blast_Score=147, Evalue=5e-35,
Organism=Drosophila melanogaster, GI24649535, Length=1300, Percent_Identity=21.7692307692308, Blast_Score=137, Evalue=5e-32,
Organism=Drosophila melanogaster, GI19922276, Length=423, Percent_Identity=28.3687943262411, Blast_Score=122, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24642557, Length=217, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24584683, Length=274, Percent_Identity=25.1824817518248, Blast_Score=68, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003395
- InterPro:   IPR010935
- InterPro:   IPR011890 [H]

Pfam domain/function: PF06470 SMC_hinge; PF02463 SMC_N [H]

EC number: NA

Molecular weight: Translated: 134804; Mature: 134673

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVILMPHCRFHGPRILWIKGLGAGFTGKAPAGLVRAVPGISSPMRLSTIKLSGFKSFVD
CCEEEECCCCCCCCEEEEEEECCCCCCCCCCHHHHHHCCCCCCCCEEEEEEEHHHHHHCC
PTTLHLPTNMTGIVGPNGCGKSNIIDAVRWVMGESSASRLRGDSLTDVIFSGSSARKPVS
CCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHCCCCHHHHHCCCCCCCCCHH
QATVELIFDNSDHTISGEFASFNEISVKRLVSRDGNSAYYLNGTKCRRRDITDLFLGTGL
HHHEEEEECCCCCEECCCCCCCHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHCCC
GPRSYSIIEQGMISQIIEARPEDLRVYLEEAAGISKYKERRKETETRIRHTRENLDRLSD
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LREEITKQLAHLQRQARQAEQYQALQEERRIKDAEWKALEYRGLDGRLQGLREKLNQEET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHCHHHH
RLQQLIAEQRDAEARIETGRVRREEAAEAVAKAQADVYQVGGALARIEQQIQHQRELSHR
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHKARDEAQSQLQELTQHISGDSAKLSVLREAVATAEPQLEQLREDHEFRQESLREAEAR
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
LADWQQRWETHNRDTGEASRAGEVERTRVDYLDRQALEADRRREALVNERAGLDLEALAE
HHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
AFEQIELRHETQKTSLDGLTEQVEARKHALAGLQEQQRASQGELAEVRKQAQAARGRLSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHH
LETLQQAALGQEQGAAVAWLKSRGLDSSARVGERISVESGWENAVEGALGQLIEGVLVEA
HHHHHHHHCCHHCCCHHHHHHHCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
PEQLVDALGELGDGRIALVSSATDNASFAPTSLAAKVQGPIAIRRLLARLHTAEDLDAAR
HHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHCHHHHHHHH
TLQRSLPEGDSVITRNGERLGEGWVRVSRSGAAKQGALLREREIQELRTQIETLQEREAE
HHHHHCCCCCCEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEHQLSSFREQLLAAEQQREDAQRQLYMAHRSVSELAGQLQSQQGKVDAARTRIERIETE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LAQLLETLDTSREQAREARAKLEDAVTLMGDLQGTREALESERRQLTDARDQARDAARGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDAMHALALTLESQRTQIASLSQTLERMDSQRGQLDTRLEDLVAQLSEGDSPVETLEHEH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
QAALSERVRTERALGEARTLLDSIDSELRSFEQTRQQRDEQALAQRERISQRKLDQQALV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNAEQLEAAVVKAGFVLEEVVNGLPESANVAEWEAAVGQIDGRMRRLEPVNLAAIQEYGE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AAQRSEYLDAQNLDLNTALETLEEAIRKIDRETRGRFKDTFDRVNSGVQALYPRLFGGGH
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
AYLELTGEDLLDTGVTIMARPPGKRVSSISLLSGGEKAMTAVALVFAIFQLNPAPFCLLD
EEEEECCHHHHHCCCEEEECCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEC
EVDAPLDEANVGRLANMVREMSEKVQFLFVSHNKATMEAARQLSGVTMREPGVSRLVSVD
CCCCCCCCCHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHCCCCCCCCCHHHHHHCC
LEEAARLAGAA
HHHHHHHCCCC
>Mature Secondary Structure 
PVILMPHCRFHGPRILWIKGLGAGFTGKAPAGLVRAVPGISSPMRLSTIKLSGFKSFVD
CEEEECCCCCCCCEEEEEEECCCCCCCCCCHHHHHHCCCCCCCCEEEEEEEHHHHHHCC
PTTLHLPTNMTGIVGPNGCGKSNIIDAVRWVMGESSASRLRGDSLTDVIFSGSSARKPVS
CCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHCCCCHHHHHCCCCCCCCCHH
QATVELIFDNSDHTISGEFASFNEISVKRLVSRDGNSAYYLNGTKCRRRDITDLFLGTGL
HHHEEEEECCCCCEECCCCCCCHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHCCC
GPRSYSIIEQGMISQIIEARPEDLRVYLEEAAGISKYKERRKETETRIRHTRENLDRLSD
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LREEITKQLAHLQRQARQAEQYQALQEERRIKDAEWKALEYRGLDGRLQGLREKLNQEET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHCHHHH
RLQQLIAEQRDAEARIETGRVRREEAAEAVAKAQADVYQVGGALARIEQQIQHQRELSHR
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHKARDEAQSQLQELTQHISGDSAKLSVLREAVATAEPQLEQLREDHEFRQESLREAEAR
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
LADWQQRWETHNRDTGEASRAGEVERTRVDYLDRQALEADRRREALVNERAGLDLEALAE
HHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
AFEQIELRHETQKTSLDGLTEQVEARKHALAGLQEQQRASQGELAEVRKQAQAARGRLSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHH
LETLQQAALGQEQGAAVAWLKSRGLDSSARVGERISVESGWENAVEGALGQLIEGVLVEA
HHHHHHHHCCHHCCCHHHHHHHCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
PEQLVDALGELGDGRIALVSSATDNASFAPTSLAAKVQGPIAIRRLLARLHTAEDLDAAR
HHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHCHHHHHHHH
TLQRSLPEGDSVITRNGERLGEGWVRVSRSGAAKQGALLREREIQELRTQIETLQEREAE
HHHHHCCCCCCEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEHQLSSFREQLLAAEQQREDAQRQLYMAHRSVSELAGQLQSQQGKVDAARTRIERIETE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LAQLLETLDTSREQAREARAKLEDAVTLMGDLQGTREALESERRQLTDARDQARDAARGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDAMHALALTLESQRTQIASLSQTLERMDSQRGQLDTRLEDLVAQLSEGDSPVETLEHEH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
QAALSERVRTERALGEARTLLDSIDSELRSFEQTRQQRDEQALAQRERISQRKLDQQALV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNAEQLEAAVVKAGFVLEEVVNGLPESANVAEWEAAVGQIDGRMRRLEPVNLAAIQEYGE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AAQRSEYLDAQNLDLNTALETLEEAIRKIDRETRGRFKDTFDRVNSGVQALYPRLFGGGH
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
AYLELTGEDLLDTGVTIMARPPGKRVSSISLLSGGEKAMTAVALVFAIFQLNPAPFCLLD
EEEEECCHHHHHCCCEEEECCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEC
EVDAPLDEANVGRLANMVREMSEKVQFLFVSHNKATMEAARQLSGVTMREPGVSRLVSVD
CCCCCCCCCHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHCCCCCCCCCHHHHHHCC
LEEAARLAGAA
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8654983; 9384377; 7584053; 9701812; 9573042 [H]