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The map label for this gene is ugd [H]

Identifier: 21242302

GI number: 21242302

Start: 1791818

End: 1793167

Strand: Direct

Name: ugd [H]

Synonym: XAC1551

Alternate gene names: 21242302

Gene position: 1791818-1793167 (Clockwise)

Preceding gene: 21242301

Following gene: 21242303

Centisome position: 34.62

GC content: 62.96

Gene sequence:

>1350_bases
ATGCGCGTTGCGATCTTCGGCACCGGCTACGTGGGTCTTGTGACCGGTGCCTGCCTGGCGGAAGTGGGGCATCAGGTCGT
CTGTGTGGATATCGATCAAGCCAAGCTTGATGCCCTCAATCGCGGGCTGATTCCGATCTACGAGCCCGGCCTGGAGCCGA
TGGTGAAGGCCAACCATGCCGCCGGCAGGTTGCGCTTCACCAGCGACGCGGCTGCCGCGATCGCGCATGGCGAGATCACC
TTCATTGCCGTAGGCACGCCGGCCGACCAGGATGGGAGTGCCGACCTGCAATACGTGCTGGCAGTTGCGCGCACGGTGGG
CCGGCATATCGACGGCCCGGCGATCGTGGTCAACAAGTCAACGGTGCCGGTCGGCACGGCCGATCGCGTACGCGTGGCGA
TCCAGGAAGAACTGGCCGCGCGCGGAGTGGCGCACGACTTCGATGTCGTCTCCAACCCCGAATTCCTCAAGGAAGGCGAC
GCGGTGGCCGACTGCATGCGCCCCGACCGCATCGTGATCGGCGCCAAGAAGCCGGCAGCCATTGCGCGCATGCGTCGCCT
GTACGCACCGTTCAATCGCAACCGCGATCGCATCGTCGAAATGGACGTGCGTTCGGCCGAGCTGACCAAGTACGCGGCCA
ACGCGATGCTGGCGACCAAGATCAGTTTCATGAACGAGATCGCCAATATTGCCGAGCGTGTCGGTGCCGACGTCGAACAG
GTGCGTAACGGCATCGGCTCTGATCCGCGTATTGGCTGGCACTTCATCTATCCCGGCGCCGGTTACGGCGGCTCGTGCTT
CCCGAAGGACGTGCAGGCATTGGCCAAGACGGCCGAGCAGTACGGCATGCAGCCGACCCTGCTCAACGCAGTGGAAAGCG
TCAATAACGCGCAGAAGGGCCATCTGTTCGAACTGGTGCAGCGGCATTACGGCACCGAGGGTGCCGGCATTGTGGCCGGC
AAGACCTTCGCGGTGTGGGGTCTGGCGTTCAAGCCCAATACCGACGACATGCGTGCTGCGTCCAGCCGTCGCTTGATGGA
ACAGTTGTGGGAAGCCGGTGCCACCGTGCGCGTCTACGACCCTGAAGCCACTCGCGAAGCCAGGCGCATCTTCGGCGAGC
GCGATGATCTGACCTTCTGCGACAATGCCTTTTCTGCACTGGAAGATGCCGACGCACTGGTCGTGGTTACCGAGTGGAAG
CAGTTCCGGAGCCCGGACTTCGGCAAGATCAAGCAGGCCTTGAAGGACGATGTCGTCTTCGACGGCCGCAACCTTTACGA
CCCGCAAGAGATCGAAGCCGCAGGTCTGGCGTACTACGCCATTGGACGAGGCCGTTCGCTGTATGCATGA

Upstream 100 bases:

>100_bases
GGCACGCAAGGAGGGCCGATCGGACCTGACGCAACGTTGACGTTCGATGTCGAACTGATGGGTATCCTTCCCTGATCTTC
CGCAGGAGGCAGTTCATTCC

Downstream 100 bases:

>100_bases
GCAACTCCCGCTGCAAGACCGCGCGCTGGAAGCGCGGTTGATCGAATTGGAAACGCGCCTCTCCTTCCAGGAGCAGGCGC
TCAACGAACTGAGTGAAGCA

Product: UDP-glucose dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MRVAIFGTGYVGLVTGACLAEVGHQVVCVDIDQAKLDALNRGLIPIYEPGLEPMVKANHAAGRLRFTSDAAAAIAHGEIT
FIAVGTPADQDGSADLQYVLAVARTVGRHIDGPAIVVNKSTVPVGTADRVRVAIQEELAARGVAHDFDVVSNPEFLKEGD
AVADCMRPDRIVIGAKKPAAIARMRRLYAPFNRNRDRIVEMDVRSAELTKYAANAMLATKISFMNEIANIAERVGADVEQ
VRNGIGSDPRIGWHFIYPGAGYGGSCFPKDVQALAKTAEQYGMQPTLLNAVESVNNAQKGHLFELVQRHYGTEGAGIVAG
KTFAVWGLAFKPNTDDMRAASSRRLMEQLWEAGATVRVYDPEATREARRIFGERDDLTFCDNAFSALEDADALVVVTEWK
QFRSPDFGKIKQALKDDVVFDGRNLYDPQEIEAAGLAYYAIGRGRSLYA

Sequences:

>Translated_449_residues
MRVAIFGTGYVGLVTGACLAEVGHQVVCVDIDQAKLDALNRGLIPIYEPGLEPMVKANHAAGRLRFTSDAAAAIAHGEIT
FIAVGTPADQDGSADLQYVLAVARTVGRHIDGPAIVVNKSTVPVGTADRVRVAIQEELAARGVAHDFDVVSNPEFLKEGD
AVADCMRPDRIVIGAKKPAAIARMRRLYAPFNRNRDRIVEMDVRSAELTKYAANAMLATKISFMNEIANIAERVGADVEQ
VRNGIGSDPRIGWHFIYPGAGYGGSCFPKDVQALAKTAEQYGMQPTLLNAVESVNNAQKGHLFELVQRHYGTEGAGIVAG
KTFAVWGLAFKPNTDDMRAASSRRLMEQLWEAGATVRVYDPEATREARRIFGERDDLTFCDNAFSALEDADALVVVTEWK
QFRSPDFGKIKQALKDDVVFDGRNLYDPQEIEAAGLAYYAIGRGRSLYA
>Mature_449_residues
MRVAIFGTGYVGLVTGACLAEVGHQVVCVDIDQAKLDALNRGLIPIYEPGLEPMVKANHAAGRLRFTSDAAAAIAHGEIT
FIAVGTPADQDGSADLQYVLAVARTVGRHIDGPAIVVNKSTVPVGTADRVRVAIQEELAARGVAHDFDVVSNPEFLKEGD
AVADCMRPDRIVIGAKKPAAIARMRRLYAPFNRNRDRIVEMDVRSAELTKYAANAMLATKISFMNEIANIAERVGADVEQ
VRNGIGSDPRIGWHFIYPGAGYGGSCFPKDVQALAKTAEQYGMQPTLLNAVESVNNAQKGHLFELVQRHYGTEGAGIVAG
KTFAVWGLAFKPNTDDMRAASSRRLMEQLWEAGATVRVYDPEATREARRIFGERDDLTFCDNAFSALEDADALVVVTEWK
QFRSPDFGKIKQALKDDVVFDGRNLYDPQEIEAAGLAYYAIGRGRSLYA

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=471, Percent_Identity=33.7579617834395, Blast_Score=235, Evalue=6e-62,
Organism=Homo sapiens, GI296040438, Length=373, Percent_Identity=34.5844504021448, Blast_Score=188, Evalue=9e-48,
Organism=Homo sapiens, GI296040443, Length=317, Percent_Identity=34.7003154574132, Blast_Score=164, Evalue=1e-40,
Organism=Escherichia coli, GI1788340, Length=388, Percent_Identity=27.8350515463918, Blast_Score=152, Evalue=6e-38,
Organism=Escherichia coli, GI48994968, Length=445, Percent_Identity=28.5393258426966, Blast_Score=148, Evalue=8e-37,
Organism=Caenorhabditis elegans, GI17560350, Length=468, Percent_Identity=35.042735042735, Blast_Score=249, Evalue=2e-66,
Organism=Drosophila melanogaster, GI17136908, Length=474, Percent_Identity=32.7004219409283, Blast_Score=229, Evalue=3e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 48807; Mature: 48807

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVAIFGTGYVGLVTGACLAEVGHQVVCVDIDQAKLDALNRGLIPIYEPGLEPMVKANHA
CEEEEEECCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCCEEECCCCCHHHHCCCC
AGRLRFTSDAAAAIAHGEITFIAVGTPADQDGSADLQYVLAVARTVGRHIDGPAIVVNKS
CCEEEECCCHHHHEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECC
TVPVGTADRVRVAIQEELAARGVAHDFDVVSNPEFLKEGDAVADCMRPDRIVIGAKKPAA
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCHHHHHCCCCEEEEECCCCHH
IARMRRLYAPFNRNRDRIVEMDVRSAELTKYAANAMLATKISFMNEIANIAERVGADVEQ
HHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRNGIGSDPRIGWHFIYPGAGYGGSCFPKDVQALAKTAEQYGMQPTLLNAVESVNNAQKG
HHHCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC
HLFELVQRHYGTEGAGIVAGKTFAVWGLAFKPNTDDMRAASSRRLMEQLWEAGATVRVYD
HHHHHHHHHCCCCCCEEEECCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEEEC
PEATREARRIFGERDDLTFCDNAFSALEDADALVVVTEWKQFRSPDFGKIKQALKDDVVF
CHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEEECHHHHCCCCHHHHHHHHHHCEEE
DGRNLYDPQEIEAAGLAYYAIGRGRSLYA
CCCCCCCHHHHHHCCEEEEEECCCCCCCC
>Mature Secondary Structure
MRVAIFGTGYVGLVTGACLAEVGHQVVCVDIDQAKLDALNRGLIPIYEPGLEPMVKANHA
CEEEEEECCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCCEEECCCCCHHHHCCCC
AGRLRFTSDAAAAIAHGEITFIAVGTPADQDGSADLQYVLAVARTVGRHIDGPAIVVNKS
CCEEEECCCHHHHEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECC
TVPVGTADRVRVAIQEELAARGVAHDFDVVSNPEFLKEGDAVADCMRPDRIVIGAKKPAA
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCHHHHHCCCCEEEEECCCCHH
IARMRRLYAPFNRNRDRIVEMDVRSAELTKYAANAMLATKISFMNEIANIAERVGADVEQ
HHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRNGIGSDPRIGWHFIYPGAGYGGSCFPKDVQALAKTAEQYGMQPTLLNAVESVNNAQKG
HHHCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC
HLFELVQRHYGTEGAGIVAGKTFAVWGLAFKPNTDDMRAASSRRLMEQLWEAGATVRVYD
HHHHHHHHHCCCCCCEEEECCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEEEC
PEATREARRIFGERDDLTFCDNAFSALEDADALVVVTEWKQFRSPDFGKIKQALKDDVVF
CHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEEECHHHHCCCCHHHHHHHHHHCEEE
DGRNLYDPQEIEAAGLAYYAIGRGRSLYA
CCCCCCCHHHHHHCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]