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The map label for this gene is btuE [C]

Identifier: 21242300

GI number: 21242300

Start: 1790173

End: 1790730

Strand: Direct

Name: btuE [C]

Synonym: XAC1549

Alternate gene names: 21242300

Gene position: 1790173-1790730 (Clockwise)

Preceding gene: 21242293

Following gene: 21242301

Centisome position: 34.59

GC content: 60.75

Gene sequence:

>558_bases
ATGTTGCTCAATCGTCTGCTAGCTCTTGTATTGACTGGCTTTTTTGCAACGCCTGCGTTCGCTGCCGGCACCCCGGTACT
GGATGTGGAGTACCGGCCGCTGGCCGGCAAGACGCCGATCAACCTGAACCGTACCTACGGCGGCAAGGTTGTCATGGTGG
TCAACACCGCCAGCAAGTGCGGCTTCACCCCGCAGTACGAAGGTCTGGAAGCGCTCAACCATCGCTTCGGCAGCCGCGGC
TTCACCGTGCTGGGCTTTCCGTCCAACGATTTCCAAGGACAGGAACCGGGATCTGAGAAGCAGATCCAGGAATTCTGCAC
GCTGACCTATGGCGTGAAGTTCCCGATGTTTGAGAAGGTCCATGTGCTGGGTGCCGAGGCAACGCCGCTGTATCAGCGCC
TGACCCAGGCCACTGGCGTGGCGCCGGGCTGGAATTTCCACAAGTATCTGATCGGTCGCGATGGCCGGGTGGTTGCGCAG
TTCCCCAGCAAGATCAAACCGGACGATCCGAGCGTGCTGGCAGCAATCGAACGCGAGCTCAAGGCGCCGGCGCGCTGA

Upstream 100 bases:

>100_bases
CAACTATAACACCGACACGCAGGTAGTCAACTGTTTGTCATCCCCAACTGATGGCACCCCTTTATCGGTGCGCCGCCTCA
ACTATCGAAGGGCATTGCTC

Downstream 100 bases:

>100_bases
GCGCAGCGCTCGCATCGCCGCGCGCGCGTGCGACAATGCGCATTCAGCGCCATCGGTGGCGTGTCTTTTCACTTTTGGGA
AGTGCATCGAATGAAGATGG

Product: ABC transporter vitamin B12 uptake permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MLLNRLLALVLTGFFATPAFAAGTPVLDVEYRPLAGKTPINLNRTYGGKVVMVVNTASKCGFTPQYEGLEALNHRFGSRG
FTVLGFPSNDFQGQEPGSEKQIQEFCTLTYGVKFPMFEKVHVLGAEATPLYQRLTQATGVAPGWNFHKYLIGRDGRVVAQ
FPSKIKPDDPSVLAAIERELKAPAR

Sequences:

>Translated_185_residues
MLLNRLLALVLTGFFATPAFAAGTPVLDVEYRPLAGKTPINLNRTYGGKVVMVVNTASKCGFTPQYEGLEALNHRFGSRG
FTVLGFPSNDFQGQEPGSEKQIQEFCTLTYGVKFPMFEKVHVLGAEATPLYQRLTQATGVAPGWNFHKYLIGRDGRVVAQ
FPSKIKPDDPSVLAAIERELKAPAR
>Mature_185_residues
MLLNRLLALVLTGFFATPAFAAGTPVLDVEYRPLAGKTPINLNRTYGGKVVMVVNTASKCGFTPQYEGLEALNHRFGSRG
FTVLGFPSNDFQGQEPGSEKQIQEFCTLTYGVKFPMFEKVHVLGAEATPLYQRLTQATGVAPGWNFHKYLIGRDGRVVAQ
FPSKIKPDDPSVLAAIERELKAPAR

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI15618997, Length=136, Percent_Identity=43.3823529411765, Blast_Score=117, Evalue=6e-27,
Organism=Homo sapiens, GI192455698, Length=142, Percent_Identity=40.1408450704225, Blast_Score=107, Evalue=4e-24,
Organism=Homo sapiens, GI75709200, Length=196, Percent_Identity=34.1836734693878, Blast_Score=87, Evalue=9e-18,
Organism=Homo sapiens, GI90903240, Length=129, Percent_Identity=40.3100775193798, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI90903238, Length=171, Percent_Identity=34.5029239766082, Blast_Score=75, Evalue=2e-14,
Organism=Homo sapiens, GI41406084, Length=178, Percent_Identity=32.0224719101124, Blast_Score=71, Evalue=6e-13,
Organism=Homo sapiens, GI4557629, Length=145, Percent_Identity=31.0344827586207, Blast_Score=64, Evalue=7e-11,
Organism=Escherichia coli, GI1788003, Length=159, Percent_Identity=44.6540880503145, Blast_Score=144, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17506887, Length=141, Percent_Identity=36.8794326241135, Blast_Score=97, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17535473, Length=143, Percent_Identity=37.7622377622378, Blast_Score=97, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI71993584, Length=129, Percent_Identity=34.1085271317829, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI193210707, Length=156, Percent_Identity=35.8974358974359, Blast_Score=84, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17550320, Length=166, Percent_Identity=27.1084337349398, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6319721, Length=140, Percent_Identity=45.7142857142857, Blast_Score=134, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6322228, Length=139, Percent_Identity=47.4820143884892, Blast_Score=132, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6322826, Length=141, Percent_Identity=36.8794326241135, Blast_Score=105, Evalue=4e-24,
Organism=Drosophila melanogaster, GI85726443, Length=142, Percent_Identity=36.6197183098592, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24656772, Length=131, Percent_Identity=38.1679389312977, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24656777, Length=142, Percent_Identity=37.3239436619718, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24656767, Length=142, Percent_Identity=37.3239436619718, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 20277; Mature: 20277

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLNRLLALVLTGFFATPAFAAGTPVLDVEYRPLAGKTPINLNRTYGGKVVMVVNTASKC
CHHHHHHHHHHHHHHHCCHHHCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEEECHHHC
GFTPQYEGLEALNHRFGSRGFTVLGFPSNDFQGQEPGSEKQIQEFCTLTYGVKFPMFEKV
CCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHH
HVLGAEATPLYQRLTQATGVAPGWNFHKYLIGRDGRVVAQFPSKIKPDDPSVLAAIEREL
EEECCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHH
KAPAR
CCCCC
>Mature Secondary Structure
MLLNRLLALVLTGFFATPAFAAGTPVLDVEYRPLAGKTPINLNRTYGGKVVMVVNTASKC
CHHHHHHHHHHHHHHHCCHHHCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEEECHHHC
GFTPQYEGLEALNHRFGSRGFTVLGFPSNDFQGQEPGSEKQIQEFCTLTYGVKFPMFEKV
CCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHH
HVLGAEATPLYQRLTQATGVAPGWNFHKYLIGRDGRVVAQFPSKIKPDDPSVLAAIEREL
EEECCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHH
KAPAR
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]