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The map label for this gene is scoF [H]

Identifier: 21242090

GI number: 21242090

Start: 1542586

End: 1542792

Strand: Direct

Name: scoF [H]

Synonym: XAC1337

Alternate gene names: 21242090

Gene position: 1542586-1542792 (Clockwise)

Preceding gene: 21242089

Following gene: 21242091

Centisome position: 29.81

GC content: 59.9

Gene sequence:

>207_bases
ATGCCGAACGGTACCGTCAAGTGGTTCAACGACGCCAAGGGATTTGGCTTCATCTCACCGGAGGACGGCAGCGCCGATGT
CTTCGCGCACTTCTCCGCGATCAATTCCAAGGGCTTCCGCAGCCTGCAGGAAGGCCAGCGCGTCAGTTATGACGTGACCC
AGGGTCCCAAGGGTGCCCAGGCTTCGAACATCACGCCTGTCGAGTAA

Upstream 100 bases:

>100_bases
TGCACGCGGGTGATTGTCATCGGGGCATAAGCTTTGCATACTCGGCGCGTACGCACCGCCGTACACCACCCATTAATTAT
TGCAAAGGTCTCGCATCACC

Downstream 100 bases:

>100_bases
TCTGACTCGATTGTGCGGTTGAAAACCCCGCCACGGCGGGGTTTTTTTTCGCCGGTTGTGCGCGGGCAGCGATAGCCAAA
CAGAGCAGGGACGATGCTAC

Product: cold shock protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 68; Mature: 67

Protein sequence:

>68_residues
MPNGTVKWFNDAKGFGFISPEDGSADVFAHFSAINSKGFRSLQEGQRVSYDVTQGPKGAQASNITPVE

Sequences:

>Translated_68_residues
MPNGTVKWFNDAKGFGFISPEDGSADVFAHFSAINSKGFRSLQEGQRVSYDVTQGPKGAQASNITPVE
>Mature_67_residues
PNGTVKWFNDAKGFGFISPEDGSADVFAHFSAINSKGFRSLQEGQRVSYDVTQGPKGAQASNITPVE

Specific function: Inhibits DNA Replication At Both Initiation And Elongation Steps, Most Probably By Binding To The Opened, Single- Stranded Regions At Replication Forks. Plays A Regulatory Role In Chromosomal Replication In Nutrient-Depleted Cells. [C]

COG id: COG1278

COG function: function code K; Cold shock proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CSD (cold-shock) domain [H]

Homologues:

Organism=Homo sapiens, GI224586884, Length=66, Percent_Identity=48.4848484848485, Blast_Score=64, Evalue=3e-11,
Organism=Homo sapiens, GI224586882, Length=66, Percent_Identity=48.4848484848485, Blast_Score=64, Evalue=3e-11,
Organism=Homo sapiens, GI34098946, Length=66, Percent_Identity=48.4848484848485, Blast_Score=64, Evalue=3e-11,
Organism=Homo sapiens, GI156415990, Length=66, Percent_Identity=50, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1787107, Length=68, Percent_Identity=63.2352941176471, Blast_Score=95, Evalue=8e-22,
Organism=Escherichia coli, GI1786841, Length=64, Percent_Identity=60.9375, Blast_Score=92, Evalue=6e-21,
Organism=Escherichia coli, GI1789979, Length=64, Percent_Identity=59.375, Blast_Score=85, Evalue=9e-19,
Organism=Escherichia coli, GI1788126, Length=64, Percent_Identity=57.8125, Blast_Score=84, Evalue=1e-18,
Organism=Escherichia coli, GI2367114, Length=64, Percent_Identity=54.6875, Blast_Score=81, Evalue=1e-17,
Organism=Escherichia coli, GI1787839, Length=61, Percent_Identity=59.0163934426229, Blast_Score=79, Evalue=4e-17,
Organism=Escherichia coli, GI1787834, Length=64, Percent_Identity=54.6875, Blast_Score=79, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24658520, Length=62, Percent_Identity=43.5483870967742, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019844
- InterPro:   IPR012156
- InterPro:   IPR011129
- InterPro:   IPR002059
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00313 CSD [H]

EC number: NA

Molecular weight: Translated: 7293; Mature: 7162

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS00352 COLD_SHOCK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNGTVKWFNDAKGFGFISPEDGSADVFAHFSAINSKGFRSLQEGQRVSYDVTQGPKGAQ
CCCCCEEECCCCCCCCCCCCCCCCCCEEEHHHHHCCCCCHHHHCCCEEEEECCCCCCCCC
ASNITPVE
CCCCCCCC
>Mature Secondary Structure 
PNGTVKWFNDAKGFGFISPEDGSADVFAHFSAINSKGFRSLQEGQRVSYDVTQGPKGAQ
CCCCEEECCCCCCCCCCCCCCCCCCEEEHHHHHCCCCCHHHHCCCEEEEECCCCCCCCC
ASNITPVE
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA