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The map label for this gene is trx [C]

Identifier: 21242030

GI number: 21242030

Start: 1462928

End: 1463374

Strand: Reverse

Name: trx [C]

Synonym: XAC1277

Alternate gene names: 21242030

Gene position: 1463374-1462928 (Counterclockwise)

Preceding gene: 21242031

Following gene: 77748573

Centisome position: 28.27

GC content: 66.22

Gene sequence:

>447_bases
ATGACCGACGCACCGCTACTGATCGCCTGTCCGAGCTGCGCTGCGATGAACCGTATTGCGCCCACGCGCCTGCGCGATGC
ACCCAACTGCGGCAGCTGCCACAAGCCGCTGTTCCCGGGGACGCCGGTGGCCTTGTCGGCTGCAGATTTCGACAAGCATG
CGGTGCGCAGCGCATTGCCGTTGGTGGTGGATTTCTGGGCGCCCTGGTGCGGGCCATGCCTGAGCATGGCGCCGCAATTT
GCCGCAGCCGCCGCAGCATTGGAACCGCAGGTGCGCCTGGCCAAGGTGGATACCGACCTGCATCCGGCGCTGGGCACGCG
CTTTGGCATCCGCAGCATTCCCACCTTGCTGGTCATCCAGGGTGGCCAGGAACTGGGCCGTCATTCCGGCGCGGTGAGCA
GCACGCAAATCGTCACCTGGGTGCGCTCTGTCCTGAGCAAGCGGTGA

Upstream 100 bases:

>100_bases
ACGGAATCGTTTGTGGTGATCGCTACACTGGCGGCATGCAGCATGCGCCGCCAGCGATGGCCGGAGATAGCGCAGGCAGC
GCCGCCGACTGGAGACCCAC

Downstream 100 bases:

>100_bases
CGCAACACGAAGGTCAGCTGCGCATGCACGCAGCTGGCCTGCCCACCTGCAGGAAACATCACTGCGGCGCAGACGCCGCA
GTGACTGCAATCAGGCGATC

Product: thioredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 148; Mature: 147

Protein sequence:

>148_residues
MTDAPLLIACPSCAAMNRIAPTRLRDAPNCGSCHKPLFPGTPVALSAADFDKHAVRSALPLVVDFWAPWCGPCLSMAPQF
AAAAAALEPQVRLAKVDTDLHPALGTRFGIRSIPTLLVIQGGQELGRHSGAVSSTQIVTWVRSVLSKR

Sequences:

>Translated_148_residues
MTDAPLLIACPSCAAMNRIAPTRLRDAPNCGSCHKPLFPGTPVALSAADFDKHAVRSALPLVVDFWAPWCGPCLSMAPQF
AAAAAALEPQVRLAKVDTDLHPALGTRFGIRSIPTLLVIQGGQELGRHSGAVSSTQIVTWVRSVLSKR
>Mature_147_residues
TDAPLLIACPSCAAMNRIAPTRLRDAPNCGSCHKPLFPGTPVALSAADFDKHAVRSALPLVVDFWAPWCGPCLSMAPQFA
AAAAALEPQVRLAKVDTDLHPALGTRFGIRSIPTLLVIQGGQELGRHSGAVSSTQIVTWVRSVLSKR

Specific function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI5031973, Length=101, Percent_Identity=35.6435643564356, Blast_Score=77, Evalue=7e-15,
Organism=Homo sapiens, GI21361403, Length=97, Percent_Identity=31.9587628865979, Blast_Score=71, Evalue=3e-13,
Organism=Homo sapiens, GI21361657, Length=86, Percent_Identity=37.2093023255814, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788936, Length=136, Percent_Identity=41.1764705882353, Blast_Score=120, Evalue=4e-29,
Organism=Escherichia coli, GI87082331, Length=104, Percent_Identity=32.6923076923077, Blast_Score=76, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI212646193, Length=101, Percent_Identity=30.6930693069307, Blast_Score=77, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17549970, Length=101, Percent_Identity=35.6435643564356, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193209454, Length=104, Percent_Identity=29.8076923076923, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI32566189, Length=106, Percent_Identity=31.1320754716981, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17556044, Length=105, Percent_Identity=30.4761904761905, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25144092, Length=106, Percent_Identity=33.0188679245283, Blast_Score=70, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17554386, Length=85, Percent_Identity=37.6470588235294, Blast_Score=69, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17569137, Length=103, Percent_Identity=30.0970873786408, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28573567, Length=96, Percent_Identity=36.4583333333333, Blast_Score=80, Evalue=5e-16,
Organism=Drosophila melanogaster, GI21358065, Length=96, Percent_Identity=37.5, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17647799, Length=84, Percent_Identity=36.9047619047619, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19921434, Length=102, Percent_Identity=30.3921568627451, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: 1.8.1.8 [C]

Molecular weight: Translated: 15664; Mature: 15533

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDAPLLIACPSCAAMNRIAPTRLRDAPNCGSCHKPLFPGTPVALSAADFDKHAVRSALP
CCCCCEEEECCCHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHH
LVVDFWAPWCGPCLSMAPQFAAAAAALEPQVRLAKVDTDLHPALGTRFGIRSIPTLLVIQ
HHHHHHCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHCCCCHHHCCEEEEEE
GGQELGRHSGAVSSTQIVTWVRSVLSKR
CCHHHHHHCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDAPLLIACPSCAAMNRIAPTRLRDAPNCGSCHKPLFPGTPVALSAADFDKHAVRSALP
CCCCEEEECCCHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHH
LVVDFWAPWCGPCLSMAPQFAAAAAALEPQVRLAKVDTDLHPALGTRFGIRSIPTLLVIQ
HHHHHHCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHCCCCHHHCCEEEEEE
GGQELGRHSGAVSSTQIVTWVRSVLSKR
CCHHHHHHCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8652661 [H]