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The map label for this gene is rsbS [H]

Identifier: 21242023

GI number: 21242023

Start: 1453812

End: 1454174

Strand: Direct

Name: rsbS [H]

Synonym: XAC1270

Alternate gene names: 21242023

Gene position: 1453812-1454174 (Clockwise)

Preceding gene: 21242022

Following gene: 21242024

Centisome position: 28.09

GC content: 63.36

Gene sequence:

>363_bases
ATGGAGCGTATTCCGATCCTGCGGATGGGCCATCTGTTGTTGGTCACCATCCAGGTGGACATGCACGACCAGCTGGCGCT
GCAACTGCAAGACGATCTGTCCGAGAAGATCAGCGCCACCTCTGCGCGCGGCCTGTTGATCGACATTTCCGCGCTGGATA
TCGTCGATTCGTTCATCGGGCGCATGATCAGCACCATCTCCGGGCTGGCGACGCTGATGGGCGCACAAACCGTGGTGGTG
GGCATGCAGCCGGCGGTGGCGATTACCCTGGTGGAGTTGGGGCTGACCCTGCCGTCGGTGCGCACCGCGCTCGATGTCGA
GCGCGGCATGCGCCTGCTGCAGCAACCCGATGCGGCTCCATGA

Upstream 100 bases:

>100_bases
GGCCTGGACCTGCAGGGGATCGTGACCAAGGCCAACCTGGCCGATGCGTTGGCGCTGGCGCTCAAGCGCACTGGCGTGGC
CGTCAGCAGGGCGGACTGAC

Downstream 100 bases:

>100_bases
CGGCCGGCTCGCAACCGGTGCGCACCGAGCAGGATGTGGTGCTGGCGCGGCAGACCGTGCGCAAACTGGTGGTGCAATGC
GGGCTGCGGCTGGTCGATCA

Product: negative regulator of sigma-B

Products: NA

Alternate protein names: Stressosome protein rsbS [H]

Number of amino acids: Translated: 120; Mature: 120

Protein sequence:

>120_residues
MERIPILRMGHLLLVTIQVDMHDQLALQLQDDLSEKISATSARGLLIDISALDIVDSFIGRMISTISGLATLMGAQTVVV
GMQPAVAITLVELGLTLPSVRTALDVERGMRLLQQPDAAP

Sequences:

>Translated_120_residues
MERIPILRMGHLLLVTIQVDMHDQLALQLQDDLSEKISATSARGLLIDISALDIVDSFIGRMISTISGLATLMGAQTVVV
GMQPAVAITLVELGLTLPSVRTALDVERGMRLLQQPDAAP
>Mature_120_residues
MERIPILRMGHLLLVTIQVDMHDQLALQLQDDLSEKISATSARGLLIDISALDIVDSFIGRMISTISGLATLMGAQTVVV
GMQPAVAITLVELGLTLPSVRTALDVERGMRLLQQPDAAP

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645 [H]

Pfam domain/function: PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 12886; Mature: 12886

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERIPILRMGHLLLVTIQVDMHDQLALQLQDDLSEKISATSARGLLIDISALDIVDSFIG
CCCCCCEEECCEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHH
RMISTISGLATLMGAQTVVVGMQPAVAITLVELGLTLPSVRTALDVERGMRLLQQPDAAP
HHHHHHHHHHHHHCCHHEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MERIPILRMGHLLLVTIQVDMHDQLALQLQDDLSEKISATSARGLLIDISALDIVDSFIG
CCCCCCEEECCEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHH
RMISTISGLATLMGAQTVVVGMQPAVAITLVELGLTLPSVRTALDVERGMRLLQQPDAAP
HHHHHHHHHHHHHCCHHEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 8824586; 8682789 [H]