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The map label for this gene is radA [H]

Identifier: 21242016

GI number: 21242016

Start: 1442157

End: 1443548

Strand: Direct

Name: radA [H]

Synonym: XAC1263

Alternate gene names: 21242016

Gene position: 1442157-1443548 (Clockwise)

Preceding gene: 21242015

Following gene: 21242017

Centisome position: 27.86

GC content: 66.52

Gene sequence:

>1392_bases
ATGGCGAAGGCGAAAACGGCCTATGTCTGCGGCGAGTGCGGTGCCGAGTACACCAAGTGGCAGGGGCAGTGCACCGAATG
CGGTGTCTGGAACACGCTGAGCGAAATCGTGCTCGAAAGCGCCACCCCGGGCGGCAAGACATCGCCAGCGGCATCGCGGC
GTAGCGGCTGGGCCGGCAAGGCCGAGGCACCCAAGATCACTGCGCTCAAGGACGTGCAGCAGTCCGAGCAGGCGCGCGTC
TCCACCGGTATCGGCGAGTTCGATCGGGTGCTGGGTGGCGGGCTGGTGGAAGGGGCGGTGGTGCTGATCGGCGGCGACCC
AGGGATCGGCAAGTCGACGTTGCTGCTGCAGGCGCTGGCGAGCATGGCCTCCACGTTGCCGGTGTTGTATGTGACCGGCG
AGGAATCGCTGGCCCAGGTGGCCGGGCGCGCGGTGCGCCTGGATCTGCCGCTGGAAGGCCTGAACGCCCTGGCCGAAACC
GGCATCGAAAACATCCTGCAGCACGCCAGCGTGGCCCGGCCGAAGCTGATCGTGGCCGATTCGGTACAAACCTTGTGGAC
CGAGTCGTTGACCGCAGCGCCGGGCTCGGTGAGCCAGGTGCGCGAGAGCGCAGCGCGGCTGGTGCGCTATGCCAAGGAAA
CCGGCACCGCGGTGTTTCTGGTCGGCCATGTGACCAAGGAAGGCGGCATCGCCGGGCCACGCGTGCTCGAGCACATGGTC
GATGCGGTGCTGTATTTCGAAGGCGAGAGCGGCAGCCGGTTCCGCCTGCTGCGTGCGTTCAAGAACCGCTTCGGTGCGGT
CAACGAACTGGGCGTGTTCGCCATGGGCGAGAAGGGCCTCAAGGAGGTCTCCAACCCGTCGGCGATCTTCCTGTCCGGCG
GTAGCACCCAGCAGCCGGGCAGTTGCGTGATGGTCACCCGCGAAGGCACCCGCCCGCTGATGGTGGAGGTACAGGCGCTG
GTGGATGCATCGCCGTTGTCCAACCCACGCCGGGTTGCGGTGGGTCTGGAGCAGAACCGGCTGGCGATGTTGCTGGCGGT
ACTGCATCGCCATGGCGGTATCGTGGTGGGCGACCAGGACGTGTTCGTCAATGTGGTGGGCGGCATCCGCGTGCAGGAAA
CCGCGGCCGATTTGCCGGTGCTGCTGGCAGTGCTGTCGTCGCTGCGCGACCGGCCGCTGTCCGAAAAGACCATCGCGTTC
GGCGAAGTGGGGCTGTCTGGCGAAATCCGCCCGGTGCCCAATGGCGAGGACCGCCTGAAGGAAGCAGCGACCCATGGTTT
CAAGCGTGCCATCGTGCCCCGCGCCAATGCGCCCAAGACCACCAGCATCAAGGGCATGGAAATCATTGCGGTGGAGCGCT
TGAGCCAGGCATTGGAAGCGGCGGCGGACTGA

Upstream 100 bases:

>100_bases
GATTCCCGATTCCCGATTCCCGATTCCGCAAAGCCCTGCGTCGCGTACACTGAGACCGTCAGCCACTATCCTGCTGCTTC
AGCAACGATGGGCAAGAACG

Downstream 100 bases:

>100_bases
AGCCGCGCGGTGCGCGCATGTTGCGATAGGCCAGGCCAGCGACCTGCCGACGCGACGCAAGCACCGCATTGGCCATGTTC
GGGAGCAGCATGCAGCCATC

Product: DNA repair protein RadA

Products: NA

Alternate protein names: DNA repair protein sms homolog [H]

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MAKAKTAYVCGECGAEYTKWQGQCTECGVWNTLSEIVLESATPGGKTSPAASRRSGWAGKAEAPKITALKDVQQSEQARV
STGIGEFDRVLGGGLVEGAVVLIGGDPGIGKSTLLLQALASMASTLPVLYVTGEESLAQVAGRAVRLDLPLEGLNALAET
GIENILQHASVARPKLIVADSVQTLWTESLTAAPGSVSQVRESAARLVRYAKETGTAVFLVGHVTKEGGIAGPRVLEHMV
DAVLYFEGESGSRFRLLRAFKNRFGAVNELGVFAMGEKGLKEVSNPSAIFLSGGSTQQPGSCVMVTREGTRPLMVEVQAL
VDASPLSNPRRVAVGLEQNRLAMLLAVLHRHGGIVVGDQDVFVNVVGGIRVQETAADLPVLLAVLSSLRDRPLSEKTIAF
GEVGLSGEIRPVPNGEDRLKEAATHGFKRAIVPRANAPKTTSIKGMEIIAVERLSQALEAAAD

Sequences:

>Translated_463_residues
MAKAKTAYVCGECGAEYTKWQGQCTECGVWNTLSEIVLESATPGGKTSPAASRRSGWAGKAEAPKITALKDVQQSEQARV
STGIGEFDRVLGGGLVEGAVVLIGGDPGIGKSTLLLQALASMASTLPVLYVTGEESLAQVAGRAVRLDLPLEGLNALAET
GIENILQHASVARPKLIVADSVQTLWTESLTAAPGSVSQVRESAARLVRYAKETGTAVFLVGHVTKEGGIAGPRVLEHMV
DAVLYFEGESGSRFRLLRAFKNRFGAVNELGVFAMGEKGLKEVSNPSAIFLSGGSTQQPGSCVMVTREGTRPLMVEVQAL
VDASPLSNPRRVAVGLEQNRLAMLLAVLHRHGGIVVGDQDVFVNVVGGIRVQETAADLPVLLAVLSSLRDRPLSEKTIAF
GEVGLSGEIRPVPNGEDRLKEAATHGFKRAIVPRANAPKTTSIKGMEIIAVERLSQALEAAAD
>Mature_462_residues
AKAKTAYVCGECGAEYTKWQGQCTECGVWNTLSEIVLESATPGGKTSPAASRRSGWAGKAEAPKITALKDVQQSEQARVS
TGIGEFDRVLGGGLVEGAVVLIGGDPGIGKSTLLLQALASMASTLPVLYVTGEESLAQVAGRAVRLDLPLEGLNALAETG
IENILQHASVARPKLIVADSVQTLWTESLTAAPGSVSQVRESAARLVRYAKETGTAVFLVGHVTKEGGIAGPRVLEHMVD
AVLYFEGESGSRFRLLRAFKNRFGAVNELGVFAMGEKGLKEVSNPSAIFLSGGSTQQPGSCVMVTREGTRPLMVEVQALV
DASPLSNPRRVAVGLEQNRLAMLLAVLHRHGGIVVGDQDVFVNVVGGIRVQETAADLPVLLAVLSSLRDRPLSEKTIAFG
EVGLSGEIRPVPNGEDRLKEAATHGFKRAIVPRANAPKTTSIKGMEIIAVERLSQALEAAAD

Specific function: May play a role in the repair of endogenous alkylation damage [H]

COG id: COG1066

COG function: function code O; Predicted ATP-dependent serine protease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recA family. RadA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790850, Length=467, Percent_Identity=59.9571734475375, Blast_Score=558, Evalue=1e-160,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR014774
- InterPro:   IPR004504
- InterPro:   IPR008269
- InterPro:   IPR020568 [H]

Pfam domain/function: PF06745 KaiC; PF05362 Lon_C [H]

EC number: NA

Molecular weight: Translated: 48687; Mature: 48556

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: PS50162 RECA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKAKTAYVCGECGAEYTKWQGQCTECGVWNTLSEIVLESATPGGKTSPAASRRSGWAGK
CCCCCCEEEEHHCCCCHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCC
AEAPKITALKDVQQSEQARVSTGIGEFDRVLGGGLVEGAVVLIGGDPGIGKSTLLLQALA
CCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHH
SMASTLPVLYVTGEESLAQVAGRAVRLDLPLEGLNALAETGIENILQHASVARPKLIVAD
HHHHCCCEEEEECCHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEC
SVQTLWTESLTAAPGSVSQVRESAARLVRYAKETGTAVFLVGHVTKEGGIAGPRVLEHMV
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCHHHHHHHH
DAVLYFEGESGSRFRLLRAFKNRFGAVNELGVFAMGEKGLKEVSNPSAIFLSGGSTQQPG
HHEEEEECCCCCHHHHHHHHHHHCCCHHHCCEEEECCHHHHHCCCCCEEEEECCCCCCCC
SCVMVTREGTRPLMVEVQALVDASPLSNPRRVAVGLEQNRLAMLLAVLHRHGGIVVGDQD
CEEEEEECCCCCCEEEHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCEEECCCC
VFVNVVGGIRVQETAADLPVLLAVLSSLRDRPLSEKTIAFGEVGLSGEIRPVPNGEDRLK
EEEEEECCEEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCHHHHH
EAATHGFKRAIVPRANAPKTTSIKGMEIIAVERLSQALEAAAD
HHHHHHHHHHCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AKAKTAYVCGECGAEYTKWQGQCTECGVWNTLSEIVLESATPGGKTSPAASRRSGWAGK
CCCCCEEEEHHCCCCHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCC
AEAPKITALKDVQQSEQARVSTGIGEFDRVLGGGLVEGAVVLIGGDPGIGKSTLLLQALA
CCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHH
SMASTLPVLYVTGEESLAQVAGRAVRLDLPLEGLNALAETGIENILQHASVARPKLIVAD
HHHHCCCEEEEECCHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEC
SVQTLWTESLTAAPGSVSQVRESAARLVRYAKETGTAVFLVGHVTKEGGIAGPRVLEHMV
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCHHHHHHHH
DAVLYFEGESGSRFRLLRAFKNRFGAVNELGVFAMGEKGLKEVSNPSAIFLSGGSTQQPG
HHEEEEECCCCCHHHHHHHHHHHCCCHHHCCEEEECCHHHHHCCCCCEEEEECCCCCCCC
SCVMVTREGTRPLMVEVQALVDASPLSNPRRVAVGLEQNRLAMLLAVLHRHGGIVVGDQD
CEEEEEECCCCCCEEEHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCEEECCCC
VFVNVVGGIRVQETAADLPVLLAVLSSLRDRPLSEKTIAFGEVGLSGEIRPVPNGEDRLK
EEEEEECCEEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCHHHHH
EAATHGFKRAIVPRANAPKTTSIKGMEIIAVERLSQALEAAAD
HHHHHHHHHHCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]